MersV1, PubMed, Corpus, bibRecord, 001613

Staphylococcus aureus Bloodstream Infection and Endocarditis--A Prospective Cohort Study.

Identifieur interne : 001613 ( PubMed/Corpus ); précédent : 001612; suivant : 001614

Staphylococcus aureus Bloodstream Infection and Endocarditis--A Prospective Cohort Study.

Auteurs : Vincent Le Moing ; François Alla ; Thanh Doco-Lecompte ; François Delahaye ; Lionel Piroth ; Catherine Chirouze ; Pierre Tattevin ; Jean-Philippe Lavigne ; Marie-Line Erpelding ; Bruno Hoen ; François Vandenesch ; Xavier Duval

Source :

PloS one [ 1932-6203 ] ; 2015.

RBID : pubmed:26020939

English descriptors

KwdEn :
- Adult, Aged, Aged, 80 and over, Bacteremia (blood), Bacteremia (mortality), Endocarditis, Bacterial (blood), Endocarditis, Bacterial (microbiology), Endocarditis, Bacterial (mortality), Female, France (epidemiology), Hospital Mortality, Humans, Male, Middle Aged, Pneumonia, Staphylococcal (blood), Pneumonia, Staphylococcal (mortality), Prospective Studies, Risk Factors, Staphylococcus aureus.
MESH :
- geographic , epidemiology : France.
- blood : Bacteremia, Endocarditis, Bacterial, Pneumonia, Staphylococcal.
- microbiology : Endocarditis, Bacterial.
- mortality : Bacteremia, Endocarditis, Bacterial, Pneumonia, Staphylococcal.
- Adult, Aged, Aged, 80 and over, Female, Hospital Mortality, Humans, Male, Middle Aged, Prospective Studies, Risk Factors, Staphylococcus aureus.

Abstract

To update the epidemiology of S. aureus bloodstream infection (SAB) in a high-income country and its link with infective endocarditis (IE).

DOI: 10.1371/journal.pone.0127385
PubMed: 26020939

Links to Exploration step

pubmed:26020939

Le document en format XML

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<author><name sortKey="Le Moing, Vincent" sort="Le Moing, Vincent" uniqKey="Le Moing V" first="Vincent" last="Le Moing">Vincent Le Moing</name>
<affiliation><nlm:affiliation>Maladies infectieuses, CHU de Montpellier, UMI 233 Université Montpellier 1, Institut de Recherche pour le Développement, Montpellier, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Alla, Francois" sort="Alla, Francois" uniqKey="Alla F" first="François" last="Alla">François Alla</name>
<affiliation><nlm:affiliation>Université de Lorraine, Université Paris Descartes, Apemac, EA 4360, INSERM, CIC-EC, CIE6, CHU Nancy, Nancy, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Doco Lecompte, Thanh" sort="Doco Lecompte, Thanh" uniqKey="Doco Lecompte T" first="Thanh" last="Doco-Lecompte">Thanh Doco-Lecompte</name>
<affiliation><nlm:affiliation>CHU de Nancy, Nancy, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Delahaye, Francois" sort="Delahaye, Francois" uniqKey="Delahaye F" first="François" last="Delahaye">François Delahaye</name>
<affiliation><nlm:affiliation>Hospices Civils de Lyon, Université Claude Bernard, Lyon, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Piroth, Lionel" sort="Piroth, Lionel" uniqKey="Piroth L" first="Lionel" last="Piroth">Lionel Piroth</name>
<affiliation><nlm:affiliation>CHU de Dijon, UMR 1347-MERS, Université de Bourgogne, Dijon, France.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Chirouze, Catherine" sort="Chirouze, Catherine" uniqKey="Chirouze C" first="Catherine" last="Chirouze">Catherine Chirouze</name>
<affiliation><nlm:affiliation>UMR CNRS 6249 Chrono-environnement, Université de Franche-Comté, CHU de Besançon, Besançon, France.</nlm:affiliation>
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<author><name sortKey="Tattevin, Pierre" sort="Tattevin, Pierre" uniqKey="Tattevin P" first="Pierre" last="Tattevin">Pierre Tattevin</name>
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<author><name sortKey="Lavigne, Jean Philippe" sort="Lavigne, Jean Philippe" uniqKey="Lavigne J" first="Jean-Philippe" last="Lavigne">Jean-Philippe Lavigne</name>
<affiliation><nlm:affiliation>CHU Carémeau, INSERM U1047, Université Montpellier 1, Nîmes, France.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Erpelding, Marie Line" sort="Erpelding, Marie Line" uniqKey="Erpelding M" first="Marie-Line" last="Erpelding">Marie-Line Erpelding</name>
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<author><name sortKey="Hoen, Bruno" sort="Hoen, Bruno" uniqKey="Hoen B" first="Bruno" last="Hoen">Bruno Hoen</name>
<affiliation><nlm:affiliation>Université des Antilles et de la Guyane, Faculté de Médecine Hyacinthe Bastaraud, Pointe-à-Pitre, Guadeloupe, Service des maladies infectieuses, CHU, Pointe-à-Pitre, Guadeloupe, France.</nlm:affiliation>
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<author><name sortKey="Vandenesch, Francois" sort="Vandenesch, Francois" uniqKey="Vandenesch F" first="François" last="Vandenesch">François Vandenesch</name>
<affiliation><nlm:affiliation>Centre National de Référence des Staphylocoques, Hospices Civils de Lyon, Centre International de Recherche en Infectiologie, INSERM U1111, Université Lyon 1, CNRS, UMR 5308, Lyon, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Duval, Xavier" sort="Duval, Xavier" uniqKey="Duval X" first="Xavier" last="Duval">Xavier Duval</name>
<affiliation><nlm:affiliation>Université Paris Diderot, INSERM, UMR 1137, CIC 1425, AP-HP, Hôpital Bichat Claude Bernard, Paris, France.</nlm:affiliation>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Staphylococcus aureus Bloodstream Infection and Endocarditis--A Prospective Cohort Study.</title>
<author><name sortKey="Le Moing, Vincent" sort="Le Moing, Vincent" uniqKey="Le Moing V" first="Vincent" last="Le Moing">Vincent Le Moing</name>
<affiliation><nlm:affiliation>Maladies infectieuses, CHU de Montpellier, UMI 233 Université Montpellier 1, Institut de Recherche pour le Développement, Montpellier, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Alla, Francois" sort="Alla, Francois" uniqKey="Alla F" first="François" last="Alla">François Alla</name>
<affiliation><nlm:affiliation>Université de Lorraine, Université Paris Descartes, Apemac, EA 4360, INSERM, CIC-EC, CIE6, CHU Nancy, Nancy, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Doco Lecompte, Thanh" sort="Doco Lecompte, Thanh" uniqKey="Doco Lecompte T" first="Thanh" last="Doco-Lecompte">Thanh Doco-Lecompte</name>
<affiliation><nlm:affiliation>CHU de Nancy, Nancy, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Delahaye, Francois" sort="Delahaye, Francois" uniqKey="Delahaye F" first="François" last="Delahaye">François Delahaye</name>
<affiliation><nlm:affiliation>Hospices Civils de Lyon, Université Claude Bernard, Lyon, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Piroth, Lionel" sort="Piroth, Lionel" uniqKey="Piroth L" first="Lionel" last="Piroth">Lionel Piroth</name>
<affiliation><nlm:affiliation>CHU de Dijon, UMR 1347-MERS, Université de Bourgogne, Dijon, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chirouze, Catherine" sort="Chirouze, Catherine" uniqKey="Chirouze C" first="Catherine" last="Chirouze">Catherine Chirouze</name>
<affiliation><nlm:affiliation>UMR CNRS 6249 Chrono-environnement, Université de Franche-Comté, CHU de Besançon, Besançon, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Tattevin, Pierre" sort="Tattevin, Pierre" uniqKey="Tattevin P" first="Pierre" last="Tattevin">Pierre Tattevin</name>
<affiliation><nlm:affiliation>Hôpital Pontchaillou, INSERM U835, Faculté de Médecine, Université Rennes 1, IFR140, Rennes, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lavigne, Jean Philippe" sort="Lavigne, Jean Philippe" uniqKey="Lavigne J" first="Jean-Philippe" last="Lavigne">Jean-Philippe Lavigne</name>
<affiliation><nlm:affiliation>CHU Carémeau, INSERM U1047, Université Montpellier 1, Nîmes, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Erpelding, Marie Line" sort="Erpelding, Marie Line" uniqKey="Erpelding M" first="Marie-Line" last="Erpelding">Marie-Line Erpelding</name>
<affiliation><nlm:affiliation>Université de Lorraine, Université Paris Descartes, Apemac, EA 4360, INSERM, CIC-EC, CIE6, CHU Nancy, Nancy, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Hoen, Bruno" sort="Hoen, Bruno" uniqKey="Hoen B" first="Bruno" last="Hoen">Bruno Hoen</name>
<affiliation><nlm:affiliation>Université des Antilles et de la Guyane, Faculté de Médecine Hyacinthe Bastaraud, Pointe-à-Pitre, Guadeloupe, Service des maladies infectieuses, CHU, Pointe-à-Pitre, Guadeloupe, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Vandenesch, Francois" sort="Vandenesch, Francois" uniqKey="Vandenesch F" first="François" last="Vandenesch">François Vandenesch</name>
<affiliation><nlm:affiliation>Centre National de Référence des Staphylocoques, Hospices Civils de Lyon, Centre International de Recherche en Infectiologie, INSERM U1111, Université Lyon 1, CNRS, UMR 5308, Lyon, France.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Duval, Xavier" sort="Duval, Xavier" uniqKey="Duval X" first="Xavier" last="Duval">Xavier Duval</name>
<affiliation><nlm:affiliation>Université Paris Diderot, INSERM, UMR 1137, CIC 1425, AP-HP, Hôpital Bichat Claude Bernard, Paris, France.</nlm:affiliation>
</affiliation>
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<series><title level="j">PloS one</title>
<idno type="eISSN">1932-6203</idno>
<imprint><date when="2015" type="published">2015</date>
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<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Bacteremia (blood)</term>
<term>Bacteremia (mortality)</term>
<term>Endocarditis, Bacterial (blood)</term>
<term>Endocarditis, Bacterial (microbiology)</term>
<term>Endocarditis, Bacterial (mortality)</term>
<term>Female</term>
<term>France (epidemiology)</term>
<term>Hospital Mortality</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Pneumonia, Staphylococcal (blood)</term>
<term>Pneumonia, Staphylococcal (mortality)</term>
<term>Prospective Studies</term>
<term>Risk Factors</term>
<term>Staphylococcus aureus</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>France</term>
</keywords>
<keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Bacteremia</term>
<term>Endocarditis, Bacterial</term>
<term>Pneumonia, Staphylococcal</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Endocarditis, Bacterial</term>
</keywords>
<keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Bacteremia</term>
<term>Endocarditis, Bacterial</term>
<term>Pneumonia, Staphylococcal</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Female</term>
<term>Hospital Mortality</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Prospective Studies</term>
<term>Risk Factors</term>
<term>Staphylococcus aureus</term>
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<front><div type="abstract" xml:lang="en">To update the epidemiology of S. aureus bloodstream infection (SAB) in a high-income country and its link with infective endocarditis (IE).</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26020939</PMID>
<DateCompleted><Year>2016</Year>
<Month>04</Month>
<Day>01</Day>
</DateCompleted>
<DateRevised><Year>2018</Year>
<Month>11</Month>
<Day>13</Day>
</DateRevised>
<Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Electronic">1932-6203</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>10</Volume>
<Issue>5</Issue>
<PubDate><Year>2015</Year>
</PubDate>
</JournalIssue>
<Title>PloS one</Title>
<ISOAbbreviation>PLoS ONE</ISOAbbreviation>
</Journal>
<ArticleTitle>Staphylococcus aureus Bloodstream Infection and Endocarditis--A Prospective Cohort Study.</ArticleTitle>
<Pagination><MedlinePgn>e0127385</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1371/journal.pone.0127385</ELocationID>
<Abstract><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">To update the epidemiology of S. aureus bloodstream infection (SAB) in a high-income country and its link with infective endocarditis (IE).</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">All consecutive adult patients with incident SAB (n = 2008) were prospectively enrolled between 2009 and 2011 in 8 university hospitals in France.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">SAB was nosocomial in 54%, non-nosocomial healthcare related in 18% and community-acquired in 26%. Methicillin resistance was present in 19% of isolates. SAB Incidence of nosocomial SAB was 0.159/1000 patients-days of hospitalization (95% confidence interval [CI] 0.111-0.219). A deep focus of infection was detected in 37%, the two most frequent were IE (11%) and pneumonia (8%). The higher rates of IE were observed in injecting drug users (IE: 38%) and patients with prosthetic (IE: 33%) or native valve disease (IE: 20%) but 40% of IE occurred in patients without heart disease nor injecting drug use. IE was more frequent in case of community-acquired (IE: 21%, adjusted odds-ratio (aOR) = 2.9, CI = 2.0-4.3) or non-nosocomial healthcare-related SAB (IE: 12%, aOR = 2.3, CI = 1.4-3.5). S. aureus meningitis (IE: 59%), persistent bacteremia at 48 hours (IE: 25%) and C-reactive protein > 190 mg/L (IE: 15%) were also independently associated with IE. Criteria for severe sepsis or septic shock were met in 30% of SAB without IE (overall in hospital mortality rate 24%) and in 51% of IE (overall in hospital mortality rate 35%).</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">SAB is still a severe disease, mostly related to healthcare in a high-income country. IE is the most frequent complication and occurs frequently in patients without known predisposing conditions.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Le Moing</LastName>
<ForeName>Vincent</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>Maladies infectieuses, CHU de Montpellier, UMI 233 Université Montpellier 1, Institut de Recherche pour le Développement, Montpellier, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Alla</LastName>
<ForeName>François</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Université de Lorraine, Université Paris Descartes, Apemac, EA 4360, INSERM, CIC-EC, CIE6, CHU Nancy, Nancy, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Doco-Lecompte</LastName>
<ForeName>Thanh</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>CHU de Nancy, Nancy, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Delahaye</LastName>
<ForeName>François</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Hospices Civils de Lyon, Université Claude Bernard, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Piroth</LastName>
<ForeName>Lionel</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>CHU de Dijon, UMR 1347-MERS, Université de Bourgogne, Dijon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chirouze</LastName>
<ForeName>Catherine</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>UMR CNRS 6249 Chrono-environnement, Université de Franche-Comté, CHU de Besançon, Besançon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Tattevin</LastName>
<ForeName>Pierre</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Hôpital Pontchaillou, INSERM U835, Faculté de Médecine, Université Rennes 1, IFR140, Rennes, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lavigne</LastName>
<ForeName>Jean-Philippe</ForeName>
<Initials>JP</Initials>
<AffiliationInfo><Affiliation>CHU Carémeau, INSERM U1047, Université Montpellier 1, Nîmes, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Erpelding</LastName>
<ForeName>Marie-Line</ForeName>
<Initials>ML</Initials>
<AffiliationInfo><Affiliation>Université de Lorraine, Université Paris Descartes, Apemac, EA 4360, INSERM, CIC-EC, CIE6, CHU Nancy, Nancy, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hoen</LastName>
<ForeName>Bruno</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Université des Antilles et de la Guyane, Faculté de Médecine Hyacinthe Bastaraud, Pointe-à-Pitre, Guadeloupe, Service des maladies infectieuses, CHU, Pointe-à-Pitre, Guadeloupe, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Vandenesch</LastName>
<ForeName>François</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Centre National de Référence des Staphylocoques, Hospices Civils de Lyon, Centre International de Recherche en Infectiologie, INSERM U1111, Université Lyon 1, CNRS, UMR 5308, Lyon, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Duval</LastName>
<ForeName>Xavier</ForeName>
<Initials>X</Initials>
<AffiliationInfo><Affiliation>Université Paris Diderot, INSERM, UMR 1137, CIC 1425, AP-HP, Hôpital Bichat Claude Bernard, Paris, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><CollectiveName>VIRSTA study group</CollectiveName>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016430">Clinical Trial</PublicationType>
<PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D016448">Multicenter Study</PublicationType>
<PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2015</Year>
<Month>05</Month>
<Day>28</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>PLoS One</MedlineTA>
<NlmUniqueID>101285081</NlmUniqueID>
<ISSNLinking>1932-6203</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016470" MajorTopicYN="Y">Bacteremia</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName>
<QualifierName UI="Q000401" MajorTopicYN="N">mortality</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004697" MajorTopicYN="Y">Endocarditis, Bacterial</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
<QualifierName UI="Q000401" MajorTopicYN="N">mortality</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005602" MajorTopicYN="N" Type="Geographic">France</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D017052" MajorTopicYN="Y">Hospital Mortality</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011023" MajorTopicYN="Y">Pneumonia, Staphylococcal</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName>
<QualifierName UI="Q000401" MajorTopicYN="N">mortality</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012307" MajorTopicYN="N">Risk Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013211" MajorTopicYN="Y">Staphylococcus aureus</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<InvestigatorList><Investigator ValidYN="Y"><LastName>Chirouze</LastName>
<ForeName>Catherine</ForeName>
<Initials>C</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Curlier</LastName>
<ForeName>Elodie</ForeName>
<Initials>E</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Descottes-Genon</LastName>
<ForeName>Cécile</ForeName>
<Initials>C</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Hoen</LastName>
<ForeName>Bruno</ForeName>
<Initials>B</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Patry</LastName>
<ForeName>Isabelle</ForeName>
<Initials>I</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Vettoretti</LastName>
<ForeName>Lucie</ForeName>
<Initials>L</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Chavanet</LastName>
<ForeName>Pascal</ForeName>
<Initials>P</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Eicher</LastName>
<ForeName>Jean-Christophe</ForeName>
<Initials>JC</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Gohier-Treuvelot</LastName>
<ForeName>Sandrine</ForeName>
<Initials>S</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Greusard</LastName>
<ForeName>Marie-Christine</ForeName>
<Initials>MC</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Neuwirth</LastName>
<ForeName>Catherine</ForeName>
<Initials>C</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Péchinot</LastName>
<ForeName>André</ForeName>
<Initials>A</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Piroth</LastName>
<ForeName>Lionel</ForeName>
<Initials>L</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Célard</LastName>
<ForeName>Marie</ForeName>
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Staphylococcus aureus Bloodstream Infection and Endocarditis--A Prospective Cohort Study.

Staphylococcus aureus Bloodstream Infection and Endocarditis--A Prospective Cohort Study.

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