Multifacility Outbreak of Middle East Respiratory Syndrome in Taif, Saudi Arabia.
Identifieur interne : 001331 ( PubMed/Corpus ); précédent : 001330; suivant : 001332Multifacility Outbreak of Middle East Respiratory Syndrome in Taif, Saudi Arabia.
Auteurs : Abdullah Assiri ; Glen R. Abedi ; Abdulaziz A. Bin Saeed ; Mutwakil A. Abdalla ; Malak Al-Masry ; Abdul Jamil Choudhry ; Xiaoyan Lu ; Dean D. Erdman ; Kathleen Tatti ; Alison M. Binder ; Jessica Rudd ; Jerome Tokars ; Congrong Miao ; Hussain Alarbash ; Randa Nooh ; Mark Pallansch ; Susan I. Gerber ; John T. WatsonSource :
- Emerging infectious diseases [ 1080-6059 ] ; 2016.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Aged, 80 and over, Coronavirus Infections (epidemiology), Coronavirus Infections (virology), Cross Infection (epidemiology), Cross Infection (virology), Disease Outbreaks, Female, Health Personnel, Humans, Infection Control (methods), Male, Middle Aged, Middle East Respiratory Syndrome Coronavirus (genetics), Middle East Respiratory Syndrome Coronavirus (isolation & purification), RNA, Viral (genetics), Saudi Arabia (epidemiology), Young Adult.
- MESH :
- chemical , genetics : RNA, Viral.
- geographic , epidemiology : Saudi Arabia.
- epidemiology : Coronavirus Infections, Cross Infection.
- genetics : Middle East Respiratory Syndrome Coronavirus.
- isolation & purification : Middle East Respiratory Syndrome Coronavirus.
- methods : Infection Control.
- virology : Coronavirus Infections, Cross Infection.
- Adolescent, Adult, Aged, Aged, 80 and over, Disease Outbreaks, Female, Health Personnel, Humans, Male, Middle Aged, Young Adult.
Abstract
Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) is a novel respiratory pathogen first reported in 2012. During September 2014-January 2015, an outbreak of 38 cases of MERS was reported from 4 healthcare facilities in Taif, Saudi Arabia; 21 of the 38 case-patients died. Clinical and public health records showed that 13 patients were healthcare personnel (HCP). Fifteen patients, including 4 HCP, were associated with 1 dialysis unit. Three additional HCP in this dialysis unit had serologic evidence of MERS-CoV infection. Viral RNA was amplified from acute-phase serum specimens of 15 patients, and full spike gene-coding sequencing was obtained from 10 patients who formed a discrete cluster; sequences from specimens of 9 patients were closely related. Similar gene sequences among patients unlinked by time or location suggest unrecognized viral transmission. Circulation persisted in multiple healthcare settings over an extended period, underscoring the importance of strengthening MERS-CoV surveillance and infection-control practices.
DOI: 10.3201/eid2201.151370
PubMed: 26692003
Links to Exploration step
pubmed:26692003Le document en format XML
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<front><div type="abstract" xml:lang="en">Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) is a novel respiratory pathogen first reported in 2012. During September 2014-January 2015, an outbreak of 38 cases of MERS was reported from 4 healthcare facilities in Taif, Saudi Arabia; 21 of the 38 case-patients died. Clinical and public health records showed that 13 patients were healthcare personnel (HCP). Fifteen patients, including 4 HCP, were associated with 1 dialysis unit. Three additional HCP in this dialysis unit had serologic evidence of MERS-CoV infection. Viral RNA was amplified from acute-phase serum specimens of 15 patients, and full spike gene-coding sequencing was obtained from 10 patients who formed a discrete cluster; sequences from specimens of 9 patients were closely related. Similar gene sequences among patients unlinked by time or location suggest unrecognized viral transmission. Circulation persisted in multiple healthcare settings over an extended period, underscoring the importance of strengthening MERS-CoV surveillance and infection-control practices. </div>
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Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001331 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 001331 | SxmlIndent | more
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{{Explor lien |wiki= Sante |area= MersV1 |flux= PubMed |étape= Corpus |type= RBID |clé= pubmed:26692003 |texte= Multifacility Outbreak of Middle East Respiratory Syndrome in Taif, Saudi Arabia. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:26692003" \ | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \ | NlmPubMed2Wicri -a MersV1
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