MersV1, PubMed, Checkpoint, bibRecord, 000F70

Multifacility Outbreak of Middle East Respiratory Syndrome in Taif, Saudi Arabia.

Identifieur interne : 000F70 ( PubMed/Checkpoint ); précédent : 000F69; suivant : 000F71

Multifacility Outbreak of Middle East Respiratory Syndrome in Taif, Saudi Arabia.

Auteurs : Abdullah Assiri ; Glen R. Abedi ; Abdulaziz A. Bin Saeed ; Mutwakil A. Abdalla ; Malak Al-Masry ; Abdul Jamil Choudhry ; Xiaoyan Lu ; Dean D. Erdman ; Kathleen Tatti ; Alison M. Binder ; Jessica Rudd ; Jerome Tokars ; Congrong Miao ; Hussain Alarbash ; Randa Nooh ; Mark Pallansch ; Susan I. Gerber ; John T. Watson

Source :

Emerging infectious diseases [ 1080-6059 ] ; 2016.

RBID : pubmed:26692003

Descripteurs français

KwdFr :
- ARN viral (génétique), Adolescent, Adulte, Adulte d'âge moyen, Arabie saoudite (épidémiologie), Coronavirus du syndrome respiratoire du Moyen-Orient (génétique), Coronavirus du syndrome respiratoire du Moyen-Orient (isolement et purification), Femelle, Flambées de maladies, Humains, Infection croisée (virologie), Infection croisée (épidémiologie), Infections à coronavirus (virologie), Infections à coronavirus (épidémiologie), Jeune adulte, Lutte contre l'infection (), Mâle, Personnel de santé, Sujet âgé, Sujet âgé de 80 ans ou plus.
MESH :
- génétique : ARN viral, Coronavirus du syndrome respiratoire du Moyen-Orient.
- isolement et purification : Coronavirus du syndrome respiratoire du Moyen-Orient.
- virologie : Infection croisée, Infections à coronavirus.
- épidémiologie : Arabie saoudite, Infection croisée, Infections à coronavirus.
- Adolescent, Adulte, Adulte d'âge moyen, Femelle, Flambées de maladies, Humains, Jeune adulte, Lutte contre l'infection, Mâle, Personnel de santé, Sujet âgé, Sujet âgé de 80 ans ou plus.
Wicri :
- geographic : Arabie saoudite.

English descriptors

KwdEn :
- Adolescent, Adult, Aged, Aged, 80 and over, Coronavirus Infections (epidemiology), Coronavirus Infections (virology), Cross Infection (epidemiology), Cross Infection (virology), Disease Outbreaks, Female, Health Personnel, Humans, Infection Control (methods), Male, Middle Aged, Middle East Respiratory Syndrome Coronavirus (genetics), Middle East Respiratory Syndrome Coronavirus (isolation & purification), RNA, Viral (genetics), Saudi Arabia (epidemiology), Young Adult.
MESH :
- chemical , genetics : RNA, Viral.
- geographic , epidemiology : Saudi Arabia.
- epidemiology : Coronavirus Infections, Cross Infection.
- genetics : Middle East Respiratory Syndrome Coronavirus.
- isolation & purification : Middle East Respiratory Syndrome Coronavirus.
- methods : Infection Control.
- virology : Coronavirus Infections, Cross Infection.
- Adolescent, Adult, Aged, Aged, 80 and over, Disease Outbreaks, Female, Health Personnel, Humans, Male, Middle Aged, Young Adult.

Abstract

Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) is a novel respiratory pathogen first reported in 2012. During September 2014-January 2015, an outbreak of 38 cases of MERS was reported from 4 healthcare facilities in Taif, Saudi Arabia; 21 of the 38 case-patients died. Clinical and public health records showed that 13 patients were healthcare personnel (HCP). Fifteen patients, including 4 HCP, were associated with 1 dialysis unit. Three additional HCP in this dialysis unit had serologic evidence of MERS-CoV infection. Viral RNA was amplified from acute-phase serum specimens of 15 patients, and full spike gene-coding sequencing was obtained from 10 patients who formed a discrete cluster; sequences from specimens of 9 patients were closely related. Similar gene sequences among patients unlinked by time or location suggest unrecognized viral transmission. Circulation persisted in multiple healthcare settings over an extended period, underscoring the importance of strengthening MERS-CoV surveillance and infection-control practices.

DOI: 10.3201/eid2201.151370
PubMed: 26692003

Affiliations:

Links toward previous steps (curation, corpus...)

to stream PubMed, to step Corpus: 001331
to stream PubMed, to step Curation: 001331

Links to Exploration step

pubmed:26692003

Le document en format XML

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<front><div type="abstract" xml:lang="en">Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) is a novel respiratory pathogen first reported in 2012. During September 2014-January 2015, an outbreak of 38 cases of MERS was reported from 4 healthcare facilities in Taif, Saudi Arabia; 21 of the 38 case-patients died. Clinical and public health records showed that 13 patients were healthcare personnel (HCP). Fifteen patients, including 4 HCP, were associated with 1 dialysis unit. Three additional HCP in this dialysis unit had serologic evidence of MERS-CoV infection. Viral RNA was amplified from acute-phase serum specimens of 15 patients, and full spike gene-coding sequencing was obtained from 10 patients who formed a discrete cluster; sequences from specimens of 9 patients were closely related. Similar gene sequences among patients unlinked by time or location suggest unrecognized viral transmission. Circulation persisted in multiple healthcare settings over an extended period, underscoring the importance of strengthening MERS-CoV surveillance and infection-control practices. </div>
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<Day>19</Day>
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<Month>11</Month>
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<Abstract><AbstractText>Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) is a novel respiratory pathogen first reported in 2012. During September 2014-January 2015, an outbreak of 38 cases of MERS was reported from 4 healthcare facilities in Taif, Saudi Arabia; 21 of the 38 case-patients died. Clinical and public health records showed that 13 patients were healthcare personnel (HCP). Fifteen patients, including 4 HCP, were associated with 1 dialysis unit. Three additional HCP in this dialysis unit had serologic evidence of MERS-CoV infection. Viral RNA was amplified from acute-phase serum specimens of 15 patients, and full spike gene-coding sequencing was obtained from 10 patients who formed a discrete cluster; sequences from specimens of 9 patients were closely related. Similar gene sequences among patients unlinked by time or location suggest unrecognized viral transmission. Circulation persisted in multiple healthcare settings over an extended period, underscoring the importance of strengthening MERS-CoV surveillance and infection-control practices. </AbstractText>
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   |texte=   Multifacility Outbreak of Middle East Respiratory Syndrome in Taif, Saudi Arabia.
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Multifacility Outbreak of Middle East Respiratory Syndrome in Taif, Saudi Arabia.

Multifacility Outbreak of Middle East Respiratory Syndrome in Taif, Saudi Arabia.

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