MersV1, PubMed, Checkpoint, bibRecord, 000784

Reported Direct and Indirect Contact with Dromedary Camels among Laboratory-Confirmed MERS-CoV Cases.

Identifieur interne : 000784 ( PubMed/Checkpoint ); précédent : 000783; suivant : 000785

Reported Direct and Indirect Contact with Dromedary Camels among Laboratory-Confirmed MERS-CoV Cases.

Auteurs : Romy Conzade [Suisse] ; Rebecca Grant [Suisse] ; Mamunur Rahman Malik [Égypte] ; Amgad Elkholy [Égypte] ; Mohamed Elhakim [Égypte] ; Dalia Samhouri [Égypte] ; Peter K. Ben Embarek [Suisse] ; Maria D. Van Kerkhove [Suisse]

Source :

Viruses [ 1999-4915 ] ; 2018.

RBID : pubmed:30104551

Descripteurs français

KwdFr :
- Adulte, Adulte d'âge moyen, Animaux, Arabie saoudite (épidémiologie), Chameaux (virologie), Coronavirus du syndrome respiratoire du Moyen-Orient (isolement et purification), Femelle, Humains, Infections à coronavirus (diagnostic), Infections à coronavirus (transmission), Infections à coronavirus (épidémiologie), Mâle, Organisation mondiale de la santé, Réservoirs d'agents pathogènes (médecine vétérinaire), Réservoirs d'agents pathogènes (virologie), Sujet âgé, Zoonoses (transmission), Zoonoses (virologie), Zoonoses (épidémiologie), Études rétrospectives.
MESH :
- diagnostic : Infections à coronavirus.
- isolement et purification : Coronavirus du syndrome respiratoire du Moyen-Orient.
- médecine vétérinaire : Réservoirs d'agents pathogènes.
- virologie : Chameaux, Réservoirs d'agents pathogènes, Zoonoses.
- épidémiologie : Arabie saoudite, Infections à coronavirus, Zoonoses.
- Adulte, Adulte d'âge moyen, Animaux, Femelle, Humains, Mâle, Organisation mondiale de la santé, Sujet âgé, Études rétrospectives.
Wicri :
- geographic : Arabie saoudite.

English descriptors

KwdEn :
- Adult, Aged, Animals, Camelus (virology), Coronavirus Infections (diagnosis), Coronavirus Infections (epidemiology), Coronavirus Infections (transmission), Disease Reservoirs (veterinary), Disease Reservoirs (virology), Female, Humans, Male, Middle Aged, Middle East Respiratory Syndrome Coronavirus (isolation & purification), Retrospective Studies, Saudi Arabia (epidemiology), World Health Organization, Zoonoses (epidemiology), Zoonoses (transmission), Zoonoses (virology).
MESH :
- geographic , epidemiology : Saudi Arabia.
- diagnosis : Coronavirus Infections.
- epidemiology : Coronavirus Infections, Zoonoses.
- isolation & purification : Middle East Respiratory Syndrome Coronavirus.
- transmission : Coronavirus Infections, Zoonoses.
- veterinary : Disease Reservoirs.
- virology : Camelus, Disease Reservoirs, Zoonoses.
- Adult, Aged, Animals, Female, Humans, Male, Middle Aged, Retrospective Studies, World Health Organization.

Abstract

Dromedary camels (Camelus dromedarius) are now known to be the vertebrate animal reservoir that intermittently transmits the Middle East respiratory syndrome coronavirus (MERS-CoV) to humans. Yet, details as to the specific mechanism(s) of zoonotic transmission from dromedaries to humans remain unclear. The aim of this study was to describe direct and indirect contact with dromedaries among all cases, and then separately for primary, non-primary, and unclassified cases of laboratory-confirmed MERS-CoV reported to the World Health Organization (WHO) between 1 January 2015 and 13 April 2018. We present any reported dromedary contact: direct, indirect, and type of indirect contact. Of all 1125 laboratory-confirmed MERS-CoV cases reported to WHO during the time period, there were 348 (30.9%) primary cases, 455 (40.4%) non-primary cases, and 322 (28.6%) unclassified cases. Among primary cases, 191 (54.9%) reported contact with dromedaries: 164 (47.1%) reported direct contact, 155 (44.5%) reported indirect contact. Five (1.1%) non-primary cases also reported contact with dromedaries. Overall, unpasteurized milk was the most frequent type of dromedary product consumed. Among cases for whom exposure was systematically collected and reported to WHO, contact with dromedaries or dromedary products has played an important role in zoonotic transmission.

DOI: 10.3390/v10080425
PubMed: 30104551

Affiliations:

Suisse, Égypte

Links toward previous steps (curation, corpus...)

to stream PubMed, to step Corpus: 000816
to stream PubMed, to step Curation: 000816

Links to Exploration step

pubmed:30104551

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Reported Direct and Indirect Contact with Dromedary Camels among Laboratory-Confirmed MERS-CoV Cases.</title>
<author><name sortKey="Conzade, Romy" sort="Conzade, Romy" uniqKey="Conzade R" first="Romy" last="Conzade">Romy Conzade</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization, 1202 Geneva, Switzerland. romy.conzade@helmholtz-muenchen.de.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization, 1202 Geneva</wicri:regionArea>
<wicri:noRegion>1202 Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Grant, Rebecca" sort="Grant, Rebecca" uniqKey="Grant R" first="Rebecca" last="Grant">Rebecca Grant</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization, 1202 Geneva, Switzerland. grantr@who.int.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization, 1202 Geneva</wicri:regionArea>
<wicri:noRegion>1202 Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Malik, Mamunur Rahman" sort="Malik, Mamunur Rahman" uniqKey="Malik M" first="Mamunur Rahman" last="Malik">Mamunur Rahman Malik</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization Regional Office for the Eastern Mediterranean, 11371 Cairo, Egypt. malikm@who.int.</nlm:affiliation>
<country xml:lang="fr">Égypte</country>
<wicri:regionArea>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization Regional Office for the Eastern Mediterranean, 11371 Cairo</wicri:regionArea>
<wicri:noRegion>11371 Cairo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Elkholy, Amgad" sort="Elkholy, Amgad" uniqKey="Elkholy A" first="Amgad" last="Elkholy">Amgad Elkholy</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization Regional Office for the Eastern Mediterranean, 11371 Cairo, Egypt. elkholya@who.int.</nlm:affiliation>
<country xml:lang="fr">Égypte</country>
<wicri:regionArea>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization Regional Office for the Eastern Mediterranean, 11371 Cairo</wicri:regionArea>
<wicri:noRegion>11371 Cairo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Elhakim, Mohamed" sort="Elhakim, Mohamed" uniqKey="Elhakim M" first="Mohamed" last="Elhakim">Mohamed Elhakim</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization Regional Office for the Eastern Mediterranean, 11371 Cairo, Egypt. elhakimm@who.int.</nlm:affiliation>
<country xml:lang="fr">Égypte</country>
<wicri:regionArea>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization Regional Office for the Eastern Mediterranean, 11371 Cairo</wicri:regionArea>
<wicri:noRegion>11371 Cairo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Samhouri, Dalia" sort="Samhouri, Dalia" uniqKey="Samhouri D" first="Dalia" last="Samhouri">Dalia Samhouri</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Country Preparedness and International Health Regulations, World Health Organization Regional Office for the Eastern Mediterranean, 11371 Cairo, Egypt. samhourid@who.int.</nlm:affiliation>
<country xml:lang="fr">Égypte</country>
<wicri:regionArea>Department of Country Preparedness and International Health Regulations, World Health Organization Regional Office for the Eastern Mediterranean, 11371 Cairo</wicri:regionArea>
<wicri:noRegion>11371 Cairo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ben Embarek, Peter K" sort="Ben Embarek, Peter K" uniqKey="Ben Embarek P" first="Peter K" last="Ben Embarek">Peter K. Ben Embarek</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Food Safety and Zoonoses, World Health Organization, 1201 Geneva, Switzerland. benembarekp@who.int.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Food Safety and Zoonoses, World Health Organization, 1201 Geneva</wicri:regionArea>
<wicri:noRegion>1201 Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Van Kerkhove, Maria D" sort="Van Kerkhove, Maria D" uniqKey="Van Kerkhove M" first="Maria D" last="Van Kerkhove">Maria D. Van Kerkhove</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization, 1202 Geneva, Switzerland. vankerkhovem@who.int.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization, 1202 Geneva</wicri:regionArea>
<wicri:noRegion>1202 Geneva</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2018">2018</date>
<idno type="RBID">pubmed:30104551</idno>
<idno type="pmid">30104551</idno>
<idno type="doi">10.3390/v10080425</idno>
<idno type="wicri:Area/PubMed/Corpus">000816</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000816</idno>
<idno type="wicri:Area/PubMed/Curation">000816</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000816</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000784</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000784</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Reported Direct and Indirect Contact with Dromedary Camels among Laboratory-Confirmed MERS-CoV Cases.</title>
<author><name sortKey="Conzade, Romy" sort="Conzade, Romy" uniqKey="Conzade R" first="Romy" last="Conzade">Romy Conzade</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization, 1202 Geneva, Switzerland. romy.conzade@helmholtz-muenchen.de.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization, 1202 Geneva</wicri:regionArea>
<wicri:noRegion>1202 Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Grant, Rebecca" sort="Grant, Rebecca" uniqKey="Grant R" first="Rebecca" last="Grant">Rebecca Grant</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization, 1202 Geneva, Switzerland. grantr@who.int.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization, 1202 Geneva</wicri:regionArea>
<wicri:noRegion>1202 Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Malik, Mamunur Rahman" sort="Malik, Mamunur Rahman" uniqKey="Malik M" first="Mamunur Rahman" last="Malik">Mamunur Rahman Malik</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization Regional Office for the Eastern Mediterranean, 11371 Cairo, Egypt. malikm@who.int.</nlm:affiliation>
<country xml:lang="fr">Égypte</country>
<wicri:regionArea>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization Regional Office for the Eastern Mediterranean, 11371 Cairo</wicri:regionArea>
<wicri:noRegion>11371 Cairo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Elkholy, Amgad" sort="Elkholy, Amgad" uniqKey="Elkholy A" first="Amgad" last="Elkholy">Amgad Elkholy</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization Regional Office for the Eastern Mediterranean, 11371 Cairo, Egypt. elkholya@who.int.</nlm:affiliation>
<country xml:lang="fr">Égypte</country>
<wicri:regionArea>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization Regional Office for the Eastern Mediterranean, 11371 Cairo</wicri:regionArea>
<wicri:noRegion>11371 Cairo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Elhakim, Mohamed" sort="Elhakim, Mohamed" uniqKey="Elhakim M" first="Mohamed" last="Elhakim">Mohamed Elhakim</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization Regional Office for the Eastern Mediterranean, 11371 Cairo, Egypt. elhakimm@who.int.</nlm:affiliation>
<country xml:lang="fr">Égypte</country>
<wicri:regionArea>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization Regional Office for the Eastern Mediterranean, 11371 Cairo</wicri:regionArea>
<wicri:noRegion>11371 Cairo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Samhouri, Dalia" sort="Samhouri, Dalia" uniqKey="Samhouri D" first="Dalia" last="Samhouri">Dalia Samhouri</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Country Preparedness and International Health Regulations, World Health Organization Regional Office for the Eastern Mediterranean, 11371 Cairo, Egypt. samhourid@who.int.</nlm:affiliation>
<country xml:lang="fr">Égypte</country>
<wicri:regionArea>Department of Country Preparedness and International Health Regulations, World Health Organization Regional Office for the Eastern Mediterranean, 11371 Cairo</wicri:regionArea>
<wicri:noRegion>11371 Cairo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ben Embarek, Peter K" sort="Ben Embarek, Peter K" uniqKey="Ben Embarek P" first="Peter K" last="Ben Embarek">Peter K. Ben Embarek</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Food Safety and Zoonoses, World Health Organization, 1201 Geneva, Switzerland. benembarekp@who.int.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Food Safety and Zoonoses, World Health Organization, 1201 Geneva</wicri:regionArea>
<wicri:noRegion>1201 Geneva</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Van Kerkhove, Maria D" sort="Van Kerkhove, Maria D" uniqKey="Van Kerkhove M" first="Maria D" last="Van Kerkhove">Maria D. Van Kerkhove</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization, 1202 Geneva, Switzerland. vankerkhovem@who.int.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization, 1202 Geneva</wicri:regionArea>
<wicri:noRegion>1202 Geneva</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Viruses</title>
<idno type="eISSN">1999-4915</idno>
<imprint><date when="2018" type="published">2018</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Animals</term>
<term>Camelus (virology)</term>
<term>Coronavirus Infections (diagnosis)</term>
<term>Coronavirus Infections (epidemiology)</term>
<term>Coronavirus Infections (transmission)</term>
<term>Disease Reservoirs (veterinary)</term>
<term>Disease Reservoirs (virology)</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Middle East Respiratory Syndrome Coronavirus (isolation & purification)</term>
<term>Retrospective Studies</term>
<term>Saudi Arabia (epidemiology)</term>
<term>World Health Organization</term>
<term>Zoonoses (epidemiology)</term>
<term>Zoonoses (transmission)</term>
<term>Zoonoses (virology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Animaux</term>
<term>Arabie saoudite (épidémiologie)</term>
<term>Chameaux (virologie)</term>
<term>Coronavirus du syndrome respiratoire du Moyen-Orient (isolement et purification)</term>
<term>Femelle</term>
<term>Humains</term>
<term>Infections à coronavirus (diagnostic)</term>
<term>Infections à coronavirus (transmission)</term>
<term>Infections à coronavirus (épidémiologie)</term>
<term>Mâle</term>
<term>Organisation mondiale de la santé</term>
<term>Réservoirs d'agents pathogènes (médecine vétérinaire)</term>
<term>Réservoirs d'agents pathogènes (virologie)</term>
<term>Sujet âgé</term>
<term>Zoonoses (transmission)</term>
<term>Zoonoses (virologie)</term>
<term>Zoonoses (épidémiologie)</term>
<term>Études rétrospectives</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Saudi Arabia</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Coronavirus Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Infections à coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Zoonoses</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Middle East Respiratory Syndrome Coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Coronavirus du syndrome respiratoire du Moyen-Orient</term>
</keywords>
<keywords scheme="MESH" qualifier="médecine vétérinaire" xml:lang="fr"><term>Réservoirs d'agents pathogènes</term>
</keywords>
<keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Coronavirus Infections</term>
<term>Zoonoses</term>
</keywords>
<keywords scheme="MESH" qualifier="veterinary" xml:lang="en"><term>Disease Reservoirs</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Chameaux</term>
<term>Réservoirs d'agents pathogènes</term>
<term>Zoonoses</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Camelus</term>
<term>Disease Reservoirs</term>
<term>Zoonoses</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Arabie saoudite</term>
<term>Infections à coronavirus</term>
<term>Zoonoses</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Animals</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Retrospective Studies</term>
<term>World Health Organization</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Animaux</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Organisation mondiale de la santé</term>
<term>Sujet âgé</term>
<term>Études rétrospectives</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Arabie saoudite</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Dromedary camels (<i>Camelus dromedarius</i>
) are now known to be the vertebrate animal reservoir that intermittently transmits the Middle East respiratory syndrome coronavirus (MERS-CoV) to humans. Yet, details as to the specific mechanism(s) of zoonotic transmission from dromedaries to humans remain unclear. The aim of this study was to describe direct and indirect contact with dromedaries among all cases, and then separately for primary, non-primary, and unclassified cases of laboratory-confirmed MERS-CoV reported to the World Health Organization (WHO) between 1 January 2015 and 13 April 2018. We present any reported dromedary contact: direct, indirect, and type of indirect contact. Of all 1125 laboratory-confirmed MERS-CoV cases reported to WHO during the time period, there were 348 (30.9%) primary cases, 455 (40.4%) non-primary cases, and 322 (28.6%) unclassified cases. Among primary cases, 191 (54.9%) reported contact with dromedaries: 164 (47.1%) reported direct contact, 155 (44.5%) reported indirect contact. Five (1.1%) non-primary cases also reported contact with dromedaries. Overall, unpasteurized milk was the most frequent type of dromedary product consumed. Among cases for whom exposure was systematically collected and reported to WHO, contact with dromedaries or dromedary products has played an important role in zoonotic transmission.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">30104551</PMID>
<DateCompleted><Year>2019</Year>
<Month>03</Month>
<Day>13</Day>
</DateCompleted>
<DateRevised><Year>2019</Year>
<Month>08</Month>
<Day>07</Day>
</DateRevised>
<Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1999-4915</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>10</Volume>
<Issue>8</Issue>
<PubDate><Year>2018</Year>
<Month>08</Month>
<Day>13</Day>
</PubDate>
</JournalIssue>
<Title>Viruses</Title>
<ISOAbbreviation>Viruses</ISOAbbreviation>
</Journal>
<ArticleTitle>Reported Direct and Indirect Contact with Dromedary Camels among Laboratory-Confirmed MERS-CoV Cases.</ArticleTitle>
<ELocationID EIdType="pii" ValidYN="Y">E425</ELocationID>
<ELocationID EIdType="doi" ValidYN="Y">10.3390/v10080425</ELocationID>
<Abstract><AbstractText>Dromedary camels (<i>Camelus dromedarius</i>
) are now known to be the vertebrate animal reservoir that intermittently transmits the Middle East respiratory syndrome coronavirus (MERS-CoV) to humans. Yet, details as to the specific mechanism(s) of zoonotic transmission from dromedaries to humans remain unclear. The aim of this study was to describe direct and indirect contact with dromedaries among all cases, and then separately for primary, non-primary, and unclassified cases of laboratory-confirmed MERS-CoV reported to the World Health Organization (WHO) between 1 January 2015 and 13 April 2018. We present any reported dromedary contact: direct, indirect, and type of indirect contact. Of all 1125 laboratory-confirmed MERS-CoV cases reported to WHO during the time period, there were 348 (30.9%) primary cases, 455 (40.4%) non-primary cases, and 322 (28.6%) unclassified cases. Among primary cases, 191 (54.9%) reported contact with dromedaries: 164 (47.1%) reported direct contact, 155 (44.5%) reported indirect contact. Five (1.1%) non-primary cases also reported contact with dromedaries. Overall, unpasteurized milk was the most frequent type of dromedary product consumed. Among cases for whom exposure was systematically collected and reported to WHO, contact with dromedaries or dromedary products has played an important role in zoonotic transmission.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Conzade</LastName>
<ForeName>Romy</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization, 1202 Geneva, Switzerland. romy.conzade@helmholtz-muenchen.de.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Institute of Epidemiology, D-85764 Neuherberg, Germany. romy.conzade@helmholtz-muenchen.de.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Grant</LastName>
<ForeName>Rebecca</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization, 1202 Geneva, Switzerland. grantr@who.int.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Institut Pasteur, Centre for Global Health Research and Education, 75015 Paris, France. grantr@who.int.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Malik</LastName>
<ForeName>Mamunur Rahman</ForeName>
<Initials>MR</Initials>
<AffiliationInfo><Affiliation>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization Regional Office for the Eastern Mediterranean, 11371 Cairo, Egypt. malikm@who.int.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Elkholy</LastName>
<ForeName>Amgad</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization Regional Office for the Eastern Mediterranean, 11371 Cairo, Egypt. elkholya@who.int.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Elhakim</LastName>
<ForeName>Mohamed</ForeName>
<Initials>M</Initials>
<Identifier Source="ORCID">0000-0001-5785-1592</Identifier>
<AffiliationInfo><Affiliation>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization Regional Office for the Eastern Mediterranean, 11371 Cairo, Egypt. elhakimm@who.int.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Samhouri</LastName>
<ForeName>Dalia</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Department of Country Preparedness and International Health Regulations, World Health Organization Regional Office for the Eastern Mediterranean, 11371 Cairo, Egypt. samhourid@who.int.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ben Embarek</LastName>
<ForeName>Peter K</ForeName>
<Initials>PK</Initials>
<AffiliationInfo><Affiliation>Department of Food Safety and Zoonoses, World Health Organization, 1201 Geneva, Switzerland. benembarekp@who.int.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Van Kerkhove</LastName>
<ForeName>Maria D</ForeName>
<Initials>MD</Initials>
<AffiliationInfo><Affiliation>Department of Infectious Hazard Management, Health Emergencies Programme, World Health Organization, 1202 Geneva, Switzerland. vankerkhovem@who.int.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<GrantList CompleteYN="Y"><Grant><GrantID>001</GrantID>
<Agency>World Health Organization</Agency>
<Country>International</Country>
</Grant>
</GrantList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2018</Year>
<Month>08</Month>
<Day>13</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>Switzerland</Country>
<MedlineTA>Viruses</MedlineTA>
<NlmUniqueID>101509722</NlmUniqueID>
<ISSNLinking>1999-4915</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002162" MajorTopicYN="N">Camelus</DescriptorName>
<QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
<QualifierName UI="Q000635" MajorTopicYN="Y">transmission</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004197" MajorTopicYN="N">Disease Reservoirs</DescriptorName>
<QualifierName UI="Q000662" MajorTopicYN="Y">veterinary</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D065207" MajorTopicYN="N">Middle East Respiratory Syndrome Coronavirus</DescriptorName>
<QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012529" MajorTopicYN="N" Type="Geographic">Saudi Arabia</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014944" MajorTopicYN="N">World Health Organization</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015047" MajorTopicYN="N">Zoonoses</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
<QualifierName UI="Q000635" MajorTopicYN="Y">transmission</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">MERS-CoV</Keyword>
<Keyword MajorTopicYN="Y">dromedary camels</Keyword>
<Keyword MajorTopicYN="Y">zoonotic transmission</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2018</Year>
<Month>07</Month>
<Day>18</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised"><Year>2018</Year>
<Month>07</Month>
<Day>30</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2018</Year>
<Month>08</Month>
<Day>09</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2018</Year>
<Month>8</Month>
<Day>15</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2018</Year>
<Month>8</Month>
<Day>15</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2019</Year>
<Month>3</Month>
<Day>14</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>epublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">30104551</ArticleId>
<ArticleId IdType="pii">v10080425</ArticleId>
<ArticleId IdType="doi">10.3390/v10080425</ArticleId>
<ArticleId IdType="pmc">PMC6115845</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>Emerg Infect Dis. 2014 Jul;20(7):1231-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24964193</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Zoonoses Public Health. 2016 Feb;63(1):1-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25545147</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2016 Mar;22(3):555-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26889787</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Infect Ecol Epidemiol. 2015 Jul 15;5:28305</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26183160</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2014 Oct 2;371(14):1359-60</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25271615</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Euro Surveill. 2015 Jun 25;20(25):1-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26132766</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2014 Dec;20(12):1999-2005</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25418529</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>One Health. 2017 Mar 10;3:41-43</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28616502</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>One Health. 2016 Dec 23;3:11-16</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28616497</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Sci Transl Med. 2014 Apr 30;6(234):234ra59</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24778414</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2015 Feb 1;60(3):369-77</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25323704</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2014 Jun;20(6):1012-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24857749</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2012 Nov 8;367(19):1814-20</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23075143</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2014 Jun 26;370(26):2499-505</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24896817</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>East Mediterr Health J. 2013;19 Suppl 1:S12-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23888790</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2014 Dec;20(12):2093-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25425139</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Opin Virol. 2016 Feb;16:55-62</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26826951</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2017 Mar;23(3):550-551</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28221127</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2014 Nov 1;59(9):1225-33</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24829216</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2015 Apr;21(4):699-701</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25811546</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2016 Aug;22(8):1395-402</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27191038</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Euro Surveill. 2014 Apr 24;19(16):20781</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24786259</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):3144-3149</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29507189</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Epidemiol Health. 2015 Jul 21;37:e2015033</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26212508</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Euro Surveill. 2014 Jun 12;19(23):null</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24957744</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2014 Aug;20(8):1339-42</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25075761</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virus Genes. 2016 Dec;52(6):848-854</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27357298</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Euro Surveill. 2017 Mar 16;22(11):</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28333616</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>MBio. 2014 Feb 25;5(2):e00884-14</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24570370</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2013 Aug 1;369(5):407-16</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23782161</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2014 Jun;20(6):1049-53</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24856660</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Hosp Infect. 2018 Jun 1;:null</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29864486</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet Infect Dis. 2014 Feb;14(2):140-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24355866</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Euro Surveill. 2014 Jun 12;19(23):null</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24957745</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vector Borne Zoonotic Dis. 2017 Feb;17(2):155-159</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28009529</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2014 Aug;20(8):1319-22</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25075637</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2016 Jan;22(1):49-55</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26692185</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect Dis. 2017 Jun 1;215(11):1702-1705</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28387845</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Euro Surveill. 2013 Dec 12;18(50):20662</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24342516</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2016 Jul;22(7):1162-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27314227</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2015 Jun;21(6):1019-22</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25989145</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2014 Aug;20(8):1370-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25062254</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Euro Surveill. 2017 Mar 30;22(13):</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28382915</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Suisse</li>
<li>Égypte</li>
</country>
</list>
<tree><country name="Suisse"><noRegion><name sortKey="Conzade, Romy" sort="Conzade, Romy" uniqKey="Conzade R" first="Romy" last="Conzade">Romy Conzade</name>
</noRegion>
<name sortKey="Ben Embarek, Peter K" sort="Ben Embarek, Peter K" uniqKey="Ben Embarek P" first="Peter K" last="Ben Embarek">Peter K. Ben Embarek</name>
<name sortKey="Grant, Rebecca" sort="Grant, Rebecca" uniqKey="Grant R" first="Rebecca" last="Grant">Rebecca Grant</name>
<name sortKey="Van Kerkhove, Maria D" sort="Van Kerkhove, Maria D" uniqKey="Van Kerkhove M" first="Maria D" last="Van Kerkhove">Maria D. Van Kerkhove</name>
</country>
<country name="Égypte"><noRegion><name sortKey="Malik, Mamunur Rahman" sort="Malik, Mamunur Rahman" uniqKey="Malik M" first="Mamunur Rahman" last="Malik">Mamunur Rahman Malik</name>
</noRegion>
<name sortKey="Elhakim, Mohamed" sort="Elhakim, Mohamed" uniqKey="Elhakim M" first="Mohamed" last="Elhakim">Mohamed Elhakim</name>
<name sortKey="Elkholy, Amgad" sort="Elkholy, Amgad" uniqKey="Elkholy A" first="Amgad" last="Elkholy">Amgad Elkholy</name>
<name sortKey="Samhouri, Dalia" sort="Samhouri, Dalia" uniqKey="Samhouri D" first="Dalia" last="Samhouri">Dalia Samhouri</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/PubMed/Checkpoint

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000784 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 000784 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    MersV1
   |flux=    PubMed
   |étape=   Checkpoint
   |type=    RBID
   |clé=     pubmed:30104551
   |texte=   Reported Direct and Indirect Contact with Dromedary Camels among Laboratory-Confirmed MERS-CoV Cases.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i   -Sk "pubmed:30104551" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd   \
       | NlmPubMed2Wicri -a MersV1

This area was generated with Dilib version V0.6.33.
Data generation: Mon Apr 20 23:26:43 2020. Site generation: Sat Mar 27 09:06:09 2021

	Serveur d'exploration MERS
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration MERS

Reported Direct and Indirect Contact with Dromedary Camels among Laboratory-Confirmed MERS-CoV Cases.

Reported Direct and Indirect Contact with Dromedary Camels among Laboratory-Confirmed MERS-CoV Cases.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki