MersV1, PubMed, Checkpoint, bibRecord, 000685

Absence of neutralizing activity in serum 1 year after successful treatment with antivirals and recovery from MERS in South Korea.

Identifieur interne : 000685 ( PubMed/Checkpoint ); précédent : 000684; suivant : 000686

Absence of neutralizing activity in serum 1 year after successful treatment with antivirals and recovery from MERS in South Korea.

Auteurs : Jun Yong Choi [Corée du Sud] ; Jin Ok Oh [Corée du Sud] ; Jin Young Ahn [Corée du Sud] ; Heun Choi [Corée du Sud] ; Jung Ho Kim [Corée du Sud] ; Hye Seong [Corée du Sud] ; Su Jin Jeong [Corée du Sud] ; Nam Su Ku [Corée du Sud] ; Joon-Sup Yeom [Corée du Sud] ; Jae-Phil Choi [Corée du Sud]

Source :

Clinical and experimental vaccine research [ 2287-3651 ] ; 2019.

RBID : pubmed:30775355

Abstract

We evaluated the neutralizing activity in serum from three patients >1 year after recovery from Middle East respiratory syndrome (MERS) associated with mild pneumonia treated with antivirals during the MERS outbreak in South Korea at 2015. The neutralizing activity in serum was measured by pseudovirus inhibition assays. Three-fold diluted serum of subjects showed only 9.7%, 10.3%, and 2.2% reductions in relative light units. So, significant neutralizing activity was not demonstrated in any sera of three patients with mild pneumonia >1 year after being successfully treated with antiviral agents and recovering from MERS coronavirus infection.

DOI: 10.7774/cevr.2019.8.1.86
PubMed: 30775355

Affiliations:

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<front><div type="abstract" xml:lang="en">We evaluated the neutralizing activity in serum from three patients >1 year after recovery from Middle East respiratory syndrome (MERS) associated with mild pneumonia treated with antivirals during the MERS outbreak in South Korea at 2015. The neutralizing activity in serum was measured by pseudovirus inhibition assays. Three-fold diluted serum of subjects showed only 9.7%, 10.3%, and 2.2% reductions in relative light units. So, significant neutralizing activity was not demonstrated in any sera of three patients with mild pneumonia >1 year after being successfully treated with antiviral agents and recovering from MERS coronavirus infection.</div>
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<Abstract><AbstractText>We evaluated the neutralizing activity in serum from three patients >1 year after recovery from Middle East respiratory syndrome (MERS) associated with mild pneumonia treated with antivirals during the MERS outbreak in South Korea at 2015. The neutralizing activity in serum was measured by pseudovirus inhibition assays. Three-fold diluted serum of subjects showed only 9.7%, 10.3%, and 2.2% reductions in relative light units. So, significant neutralizing activity was not demonstrated in any sera of three patients with mild pneumonia >1 year after being successfully treated with antiviral agents and recovering from MERS coronavirus infection.</AbstractText>
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<AffiliationInfo><Affiliation>AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea.</Affiliation>
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<name sortKey="Choi, Jae Phil" sort="Choi, Jae Phil" uniqKey="Choi J" first="Jae-Phil" last="Choi">Jae-Phil Choi</name>
<name sortKey="Jeong, Su Jin" sort="Jeong, Su Jin" uniqKey="Jeong S" first="Su Jin" last="Jeong">Su Jin Jeong</name>
<name sortKey="Kim, Jung Ho" sort="Kim, Jung Ho" uniqKey="Kim J" first="Jung Ho" last="Kim">Jung Ho Kim</name>
<name sortKey="Ku, Nam Su" sort="Ku, Nam Su" uniqKey="Ku N" first="Nam Su" last="Ku">Nam Su Ku</name>
<name sortKey="Oh, Jin Ok" sort="Oh, Jin Ok" uniqKey="Oh J" first="Jin Ok" last="Oh">Jin Ok Oh</name>
<name sortKey="Seong, Hye" sort="Seong, Hye" uniqKey="Seong H" first="Hye" last="Seong">Hye Seong</name>
<name sortKey="Yeom, Joon Sup" sort="Yeom, Joon Sup" uniqKey="Yeom J" first="Joon-Sup" last="Yeom">Joon-Sup Yeom</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/PubMed/Checkpoint

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000685 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 000685 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    MersV1
   |flux=    PubMed
   |étape=   Checkpoint
   |type=    RBID
   |clé=     pubmed:30775355
   |texte=   Absence of neutralizing activity in serum 1 year after successful treatment with antivirals and recovery from MERS in South Korea.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i   -Sk "pubmed:30775355" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd   \
       | NlmPubMed2Wicri -a MersV1

This area was generated with Dilib version V0.6.33.
Data generation: Mon Apr 20 23:26:43 2020. Site generation: Sat Mar 27 09:06:09 2021

	Serveur d'exploration MERS
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration MERS

Absence of neutralizing activity in serum 1 year after successful treatment with antivirals and recovery from MERS in South Korea.

Absence of neutralizing activity in serum 1 year after successful treatment with antivirals and recovery from MERS in South Korea.

Source :

Abstract

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Le document en format XML

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Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki