New and Emerging Infections of the Lung
Identifieur interne : 000782 ( Pmc/Curation ); précédent : 000781; suivant : 000783New and Emerging Infections of the Lung
Auteurs : Paul Tambyah ; Mas Suhaila Isa ; Christelle Xian-Ting TanSource :
- Kendig's Disorders of the Respiratory Tract in Children ; 2018.
Abstract
In this era of rapid globalization and frequent travel, emerging viral infections have gained an immense potential to spread at an unprecedented speed and scale compared with the past. This poses a significant challenge to coordinated international efforts in global surveillance and infection control.
Significantly, respiratory viral infections, spread mostly via droplet transmission, are extremely contagious and have caused significant morbidity and mortality during outbreaks in the last decade. Molecular diagnostics via reverse transcriptase polymerase chain reaction (RT-PCR) have been key in the rapid diagnosis of most of these viral infections. However, a high index of suspicion and early institution of appropriate isolation measures remain as the mainstay in the control and containment of the spread of these viral infections. Although treatment for most of the viral infections remains supportive, efficacious antiviral agents against influenza infections exist.
The infections discussed in this chapter include those first described in the 2000s: Middle East respiratory syndrome coronavirus (MERS-CoV) and metapneumovirus and rhinovirus C as well as those that have been described in the past but have reemerged in the last decade in outbreaks resulting in significant morbidity and mortality, including adenovirus, influenza virus, and enterovirus D68 (EV-D68).
Url:
DOI: 10.1016/B978-0-323-44887-1.00028-6
PubMed: NONE
PubMed Central: 7151841
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PMC:7151841Le document en format XML
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<author><name sortKey="Isa, Mas Suhaila" sort="Isa, Mas Suhaila" uniqKey="Isa M" first="Mas Suhaila" last="Isa">Mas Suhaila Isa</name>
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<front><div type="abstract" xml:lang="en"><p>In this era of rapid globalization and frequent travel, emerging viral infections have gained an immense potential to spread at an unprecedented speed and scale compared with the past. This poses a significant challenge to coordinated international efforts in global surveillance and infection control.</p>
<p>Significantly, respiratory viral infections, spread mostly via droplet transmission, are extremely contagious and have caused significant morbidity and mortality during outbreaks in the last decade. Molecular diagnostics via reverse transcriptase polymerase chain reaction (RT-PCR) have been key in the rapid diagnosis of most of these viral infections. However, a high index of suspicion and early institution of appropriate isolation measures remain as the mainstay in the control and containment of the spread of these viral infections. Although treatment for most of the viral infections remains supportive, efficacious antiviral agents against influenza infections exist.</p>
<p>The infections discussed in this chapter include those first described in the 2000s: Middle East respiratory syndrome coronavirus (MERS-CoV) and metapneumovirus and rhinovirus C as well as those that have been described in the past but have reemerged in the last decade in outbreaks resulting in significant morbidity and mortality, including adenovirus, influenza virus, and enterovirus D68 (EV-D68).</p>
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<front><journal-meta><journal-id journal-id-type="nlm-ta">Kendig's Disorders of the Respiratory Tract in Children</journal-id>
<journal-title-group><journal-title>Kendig's Disorders of the Respiratory Tract in Children</journal-title>
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<article-id pub-id-type="doi">10.1016/B978-0-323-44887-1.00028-6</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
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<title-group><article-title>New and Emerging Infections of the Lung</article-title>
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<contrib-group><contrib contrib-type="author" id="au0010"><name><surname>Tambyah</surname>
<given-names>Paul</given-names>
</name>
<degrees>MD</degrees>
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<contrib contrib-type="author" id="au0015"><name><surname>Isa</surname>
<given-names>Mas Suhaila</given-names>
</name>
<degrees>MBBS, MRCPCH (UK)</degrees>
</contrib>
<contrib contrib-type="author" id="au0020"><name><surname>Tan</surname>
<given-names>Christelle Xian-Ting</given-names>
</name>
<degrees>MBBS (S'pore), MRCPCH (UK), MMed (Paeds)</degrees>
</contrib>
</contrib-group>
<contrib-group><contrib contrib-type="editor"><name><surname>Wilmott</surname>
<given-names>Robert William</given-names>
</name>
<degrees>BSc, MB, BS, MD, FRCP (UK)</degrees>
</contrib>
</contrib-group>
<aff>IMMUNO Professor and Chair, Department of Pediatrics, Saint Louis University</aff>
<aff>Pediatrician in Chief, SSM Cardinal Glennon Children's Medical Center, St. Louis, Missouri, United States</aff>
<contrib-group><contrib contrib-type="editor"><name><surname>Deterding</surname>
<given-names>Robin</given-names>
</name>
<degrees>MD</degrees>
</contrib>
</contrib-group>
<aff>Chief, Pediatric Pulmonary Medicine, Professor of Pediatrics, Department of Pediatrics, University of Colorado, Aurora, Colorado, United States</aff>
<contrib-group><contrib contrib-type="editor"><name><surname>Li</surname>
<given-names>Albert</given-names>
</name>
<degrees>MBBch, MD, MRCPCH, MRCP(UK), FHKAM(Paeds), FHKCPaed</degrees>
</contrib>
</contrib-group>
<aff>Assistant Dean (Education), Faculty of Medicine, Professor of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong</aff>
<contrib-group><contrib contrib-type="editor"><name><surname>Ratjen</surname>
<given-names>Felix</given-names>
</name>
<degrees>MD, PhD, FRCP(C), FERS</degrees>
</contrib>
</contrib-group>
<aff>Head, Division of Respiratory Medicine</aff>
<aff>Program Head, Translational Medicine, Sellers Chair of Cystic Fibrosis</aff>
<aff>Professor, University of Toronto, Hospital for Sick Children, Toronto, Ontario, Canada</aff>
<contrib-group><contrib contrib-type="editor"><name><surname>Sly</surname>
<given-names>Peter</given-names>
</name>
<degrees>MBBS, MD, FRACP, DSc</degrees>
</contrib>
</contrib-group>
<aff>Director, Children's Lung Environment and Asthma Research Group, University of Queensland, Brisbane, Australia</aff>
<contrib-group><contrib contrib-type="editor"><name><surname>Zar</surname>
<given-names>Heather J.</given-names>
</name>
<degrees>MBBCh, FCPaeds, FRCP (Edinburgh), PhD</degrees>
</contrib>
</contrib-group>
<aff>Professor and Chair, Department of Paediatrics & Child Health</aff>
<aff>Director MRC Unit on Child & Adolescent Health, Red Cross War Memorial Children's Hospital, University of Cape Town, Cape Town, South Africa</aff>
<contrib-group><contrib contrib-type="editor"><name><surname>Bush</surname>
<given-names>Andrew</given-names>
</name>
<degrees>MB BS(Hons), MA, MD, FRCP, FRCPCH, FERS</degrees>
</contrib>
</contrib-group>
<aff>Professor of Paediatrics and Head of Section, Imperial College London</aff>
<aff>Professor of Paediatric Respirology, National Heart and Lung Institute</aff>
<aff>Consultant Paediatric Chest Physician, Royal Brompton Harefield NHS Foundation Trust, London, Great Britain</aff>
<pub-date pub-type="pmc-release"><day>13</day>
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<pub-date pub-type="ppub"><year>2019</year>
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<pub-date pub-type="epub"><day>13</day>
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<fpage>466</fpage>
<lpage>474.e2</lpage>
<permissions><copyright-statement>Copyright © 2019 Elsevier Inc. All rights reserved.</copyright-statement>
<copyright-year>2019</copyright-year>
<copyright-holder>Elsevier Inc.</copyright-holder>
<license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p>
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<abstract id="ab0010"><p>In this era of rapid globalization and frequent travel, emerging viral infections have gained an immense potential to spread at an unprecedented speed and scale compared with the past. This poses a significant challenge to coordinated international efforts in global surveillance and infection control.</p>
<p>Significantly, respiratory viral infections, spread mostly via droplet transmission, are extremely contagious and have caused significant morbidity and mortality during outbreaks in the last decade. Molecular diagnostics via reverse transcriptase polymerase chain reaction (RT-PCR) have been key in the rapid diagnosis of most of these viral infections. However, a high index of suspicion and early institution of appropriate isolation measures remain as the mainstay in the control and containment of the spread of these viral infections. Although treatment for most of the viral infections remains supportive, efficacious antiviral agents against influenza infections exist.</p>
<p>The infections discussed in this chapter include those first described in the 2000s: Middle East respiratory syndrome coronavirus (MERS-CoV) and metapneumovirus and rhinovirus C as well as those that have been described in the past but have reemerged in the last decade in outbreaks resulting in significant morbidity and mortality, including adenovirus, influenza virus, and enterovirus D68 (EV-D68).</p>
</abstract>
<kwd-group id="kwd0010"><title>Keywords</title>
<kwd>emerging infections</kwd>
<kwd>virus</kwd>
<kwd>respiratory</kwd>
</kwd-group>
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