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Coronaviruses

Identifieur interne : 000781 ( Pmc/Curation ); précédent : 000780; suivant : 000782

Coronaviruses

Auteurs : Christopher J. Burrell

Source :

RBID : PMC:7149368

Abstract

Coronaviruses possess a distinctive morphology, the name being derived from the outer fringe, or “corona” of embedded envelope protein. Members of the family Coronaviridae cause a broad spectrum of animal and human diseases. Uniquely, replication of the RNA genome proceeds through the generation of a nested set of viral mRNA molecules. Until 2003, coronaviruses attracted little interest beyond causing mild upper respiratory tract infections. This changed dramatically in 2003 with the zoonotic SARS-CoV and the more recent emergence of MERS-CoV has confirmed the coronaviruses as significant causes of severe respiratory disease.


Url:
DOI: 10.1016/B978-0-12-375156-0.00031-X
PubMed: NONE
PubMed Central: 7149368

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PMC:7149368

Le document en format XML

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<p>Coronaviruses possess a distinctive morphology, the name being derived from the outer fringe, or “corona” of embedded envelope protein. Members of the family
<italic>Coronaviridae</italic>
cause a broad spectrum of animal and human diseases. Uniquely, replication of the RNA genome proceeds through the generation of a nested set of viral mRNA molecules. Until 2003, coronaviruses attracted little interest beyond causing mild upper respiratory tract infections. This changed dramatically in 2003 with the zoonotic SARS-CoV and the more recent emergence of MERS-CoV has confirmed the coronaviruses as significant causes of severe respiratory disease.</p>
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<name sortKey="Donaldson, E F" uniqKey="Donaldson E">E.F. Donaldson</name>
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<name sortKey="Baric, R S" uniqKey="Baric R">R.S. Baric</name>
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<name sortKey="Pyrc, K" uniqKey="Pyrc K">K. Pyrc</name>
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<aff id="aff1">School of Molecular and Biomedical Science, University of Adelaide, Adelaide, South Australia, Australia</aff>
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<name>
<surname>Howard</surname>
<given-names>Colin R.</given-names>
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<aff id="aff2">College of Medicine and Dentistry, University of Birmingham, United Kingdom</aff>
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<contrib contrib-type="author" id="au0020">
<name>
<surname>Murphy</surname>
<given-names>Frederick A.</given-names>
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<aff id="aff3">University of Texas Medical Branch, Galveston, Texas, USA</aff>
<pub-date pub-type="pmc-release">
<day>11</day>
<month>11</month>
<year>2016</year>
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<copyright-statement>Copyright © 2017 Elsevier Inc. All rights reserved.</copyright-statement>
<copyright-year>2017</copyright-year>
<copyright-holder>Elsevier Inc.</copyright-holder>
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<license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p>
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<abstract id="ab0010">
<p>Coronaviruses possess a distinctive morphology, the name being derived from the outer fringe, or “corona” of embedded envelope protein. Members of the family
<italic>Coronaviridae</italic>
cause a broad spectrum of animal and human diseases. Uniquely, replication of the RNA genome proceeds through the generation of a nested set of viral mRNA molecules. Until 2003, coronaviruses attracted little interest beyond causing mild upper respiratory tract infections. This changed dramatically in 2003 with the zoonotic SARS-CoV and the more recent emergence of MERS-CoV has confirmed the coronaviruses as significant causes of severe respiratory disease.</p>
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<kwd>severe acute respiratory virus</kwd>
<kwd>Middle East respiratory virus</kwd>
<kwd>pathogenesis</kwd>
<kwd>immunity</kwd>
<kwd>human coronavirus infections</kwd>
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