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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Serological Study of An Imported Case of Middle East Respiratory Syndrome and His Close Contacts in China, 2015</title><author><name sortKey="Wang, Wen Ling" sort="Wang, Wen Ling" uniqKey="Wang W" first="Wen Ling" last="Wang">Wen Ling Wang</name><affiliation><nlm:aff id="aff1">Key Laboratory of Medical Virology and Virus Disease, National Health and Family Planning Commission of the People's Republic of China; National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China</nlm:aff></affiliation></author><author><name sortKey="Wang, Hui Juan" sort="Wang, Hui Juan" uniqKey="Wang H" first="Hui Juan" last="Wang">Hui Juan Wang</name><affiliation><nlm:aff id="aff1">Key Laboratory of Medical Virology and Virus Disease, National Health and Family Planning Commission of the People's Republic of China; National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China</nlm:aff></affiliation></author><author><name sortKey="Deng, Yao" sort="Deng, Yao" uniqKey="Deng Y" first="Yao" last="Deng">Yao Deng</name><affiliation><nlm:aff id="aff1">Key Laboratory of Medical Virology and Virus Disease, National Health and Family Planning Commission of the People's Republic of China; National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China</nlm:aff></affiliation></author><author><name sortKey="Song, Tie" sort="Song, Tie" uniqKey="Song T" first="Tie" last="Song">Tie Song</name><affiliation><nlm:aff id="aff2">Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, Guangdong, China</nlm:aff></affiliation></author><author><name sortKey="Lan, Jia Ming" sort="Lan, Jia Ming" uniqKey="Lan J" first="Jia Ming" last="Lan">Jia Ming Lan</name><affiliation><nlm:aff id="aff1">Key Laboratory of Medical Virology and Virus Disease, National Health and Family Planning Commission of the People's Republic of China; National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China</nlm:aff></affiliation></author><author><name sortKey="Wu, Gui Zhen" sort="Wu, Gui Zhen" uniqKey="Wu G" first="Gui Zhen" last="Wu">Gui Zhen Wu</name><affiliation><nlm:aff id="aff1">Key Laboratory of Medical Virology and Virus Disease, National Health and Family Planning Commission of the People's Republic of China; National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China</nlm:aff></affiliation></author><author><name sortKey="Ke, Chang Wen" sort="Ke, Chang Wen" uniqKey="Ke C" first="Chang Wen" last="Ke">Chang Wen Ke</name><affiliation><nlm:aff id="aff2">Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, Guangdong, China</nlm:aff></affiliation></author><author><name sortKey="Tan, Wen Jie" sort="Tan, Wen Jie" uniqKey="Tan W" first="Wen Jie" last="Tan">Wen Jie Tan</name><affiliation><nlm:aff id="aff1">Key Laboratory of Medical Virology and Virus Disease, National Health and Family Planning Commission of the People's Republic of China; National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27109133</idno><idno type="pmc">7135062</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135062</idno><idno type="RBID">PMC:7135062</idno><idno type="doi">10.3967/bes2016.027</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000861</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000861</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Serological Study of An Imported Case of Middle East Respiratory Syndrome and His Close Contacts in China, 2015</title><author><name sortKey="Wang, Wen Ling" sort="Wang, Wen Ling" uniqKey="Wang W" first="Wen Ling" last="Wang">Wen Ling Wang</name><affiliation><nlm:aff id="aff1">Key Laboratory of Medical Virology and Virus Disease, National Health and Family Planning Commission of the People's Republic of China; National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China</nlm:aff></affiliation></author><author><name sortKey="Wang, Hui Juan" sort="Wang, Hui Juan" uniqKey="Wang H" first="Hui Juan" last="Wang">Hui Juan Wang</name><affiliation><nlm:aff id="aff1">Key Laboratory of Medical Virology and Virus Disease, National Health and Family Planning Commission of the People's Republic of China; National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China</nlm:aff></affiliation></author><author><name sortKey="Deng, Yao" sort="Deng, Yao" uniqKey="Deng Y" first="Yao" last="Deng">Yao Deng</name><affiliation><nlm:aff id="aff1">Key Laboratory of Medical Virology and Virus Disease, National Health and Family Planning Commission of the People's Republic of China; National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China</nlm:aff></affiliation></author><author><name sortKey="Song, Tie" sort="Song, Tie" uniqKey="Song T" first="Tie" last="Song">Tie Song</name><affiliation><nlm:aff id="aff2">Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, Guangdong, China</nlm:aff></affiliation></author><author><name sortKey="Lan, Jia Ming" sort="Lan, Jia Ming" uniqKey="Lan J" first="Jia Ming" last="Lan">Jia Ming Lan</name><affiliation><nlm:aff id="aff1">Key Laboratory of Medical Virology and Virus Disease, National Health and Family Planning Commission of the People's Republic of China; National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China</nlm:aff></affiliation></author><author><name sortKey="Wu, Gui Zhen" sort="Wu, Gui Zhen" uniqKey="Wu G" first="Gui Zhen" last="Wu">Gui Zhen Wu</name><affiliation><nlm:aff id="aff1">Key Laboratory of Medical Virology and Virus Disease, National Health and Family Planning Commission of the People's Republic of China; National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China</nlm:aff></affiliation></author><author><name sortKey="Ke, Chang Wen" sort="Ke, Chang Wen" uniqKey="Ke C" first="Chang Wen" last="Ke">Chang Wen Ke</name><affiliation><nlm:aff id="aff2">Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, Guangdong, China</nlm:aff></affiliation></author><author><name sortKey="Tan, Wen Jie" sort="Tan, Wen Jie" uniqKey="Tan W" first="Wen Jie" last="Tan">Wen Jie Tan</name><affiliation><nlm:aff id="aff1">Key Laboratory of Medical Virology and Virus Disease, National Health and Family Planning Commission of the People's Republic of China; National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China</nlm:aff></affiliation></author></analytic><series><title level="j">Biomedical and Environmental Sciences</title><idno type="ISSN">0895-3988</idno><idno type="eISSN">2214-0190</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The first imported Middle East respiratory syndrome (MERS) case in China was identified in May 2015. We determined the kinetics of antibody (IgG and IgM) and neutralizing antibodies against MERS-coronavirus (MERS-CoV) in this case before discharge. Moreover, no seroconversion was found among 53 close contacts by anti-MERS IgG antibody enzyme-linked immunosorbent assay (ELISA) of paired serum samples. These findings suggest that neither community nor nosocomial transmission of MERS-CoV occurred in China.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Zaki, Am" uniqKey="Zaki A">AM Zaki</name></author><author><name sortKey="Van Boheemen, S" uniqKey="Van Boheemen S">S Van Boheemen</name></author><author><name sortKey="Bestebroer, Tm" uniqKey="Bestebroer T">TM Bestebroer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name></author><author><name sortKey="Liu, D" uniqKey="Liu D">D Liu</name></author><author><name sortKey="Shi, W" uniqKey="Shi W">W Shi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, J" uniqKey="Wu J">J Wu</name></author><author><name sortKey="Yi, L" uniqKey="Yi L">L Yi</name></author><author><name sortKey="Zou, L" uniqKey="Zou L">L Zou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Who" uniqKey="Who">WHO</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Petersen, E" uniqKey="Petersen E">E Petersen</name></author><author><name sortKey="Hui, Ds" uniqKey="Hui D">DS Hui</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S Perlman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lan, J" uniqKey="Lan J">J Lan</name></author><author><name sortKey="Deng, Y" uniqKey="Deng Y">Y Deng</name></author><author><name sortKey="Chen, H" uniqKey="Chen H">H Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Da Guan, W" uniqKey="Da Guan W">W Da Guan</name></author><author><name sortKey="Mok, Ck" uniqKey="Mok C">CK Mok</name></author><author><name sortKey="Chen, Zl" uniqKey="Chen Z">ZL Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Al Abdallat, Mm" uniqKey="Al Abdallat M">MM Al-Abdallat</name></author><author><name sortKey="Payne, Dc" uniqKey="Payne D">DC Payne</name></author><author><name sortKey="Alqasrawi, S" uniqKey="Alqasrawi S">S Alqasrawi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Breakwell, L" uniqKey="Breakwell L">L Breakwell</name></author><author><name sortKey="Pringle, K" uniqKey="Pringle K">K Pringle</name></author><author><name sortKey="Chea, N" uniqKey="Chea N">N Chea</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Gao, J" uniqKey="Gao J">J Gao</name></author><author><name sortKey="Song, P" uniqKey="Song P">P Song</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="letter"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Biomed Environ Sci</journal-id><journal-id journal-id-type="iso-abbrev">Biomed. Environ. Sci</journal-id><journal-title-group><journal-title>Biomedical and Environmental Sciences</journal-title></journal-title-group><issn pub-type="ppub">0895-3988</issn><issn pub-type="epub">2214-0190</issn><publisher><publisher-name>The Editorial Board of Biomedical and Environmental Sciences. Published by Elsevier (Singapore) Pte Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">27109133</article-id><article-id pub-id-type="pmc">7135062</article-id><article-id pub-id-type="publisher-id">S0895-3988(16)30038-1</article-id><article-id pub-id-type="doi">10.3967/bes2016.027</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Serological Study of An Imported Case of Middle East Respiratory Syndrome and His Close Contacts in China, 2015</article-title></title-group><contrib-group><contrib contrib-type="author" id="au10a"><name><surname>WANG</surname><given-names>Wen Ling</given-names></name><xref rid="aff1" ref-type="aff">a</xref><xref rid="fn1" ref-type="fn">⁁</xref></contrib><contrib contrib-type="author" id="au10b"><name><surname>WANG</surname><given-names>Hui Juan</given-names></name><xref rid="aff1" ref-type="aff">a</xref><xref rid="fn1" ref-type="fn">⁁</xref></contrib><contrib contrib-type="author" id="au10"><name><surname>DENG</surname><given-names>Yao</given-names></name><xref rid="aff1" ref-type="aff">a</xref></contrib><contrib contrib-type="author" id="au20"><name><surname>SONG</surname><given-names>Tie</given-names></name><xref rid="aff2" ref-type="aff">b</xref></contrib><contrib contrib-type="author" id="au30"><name><surname>LAN</surname><given-names>Jia Ming</given-names></name><xref rid="aff1" ref-type="aff">a</xref></contrib><contrib contrib-type="author" id="au40"><name><surname>WU</surname><given-names>Gui Zhen</given-names></name><xref rid="aff1" ref-type="aff">a</xref></contrib><contrib contrib-type="author" id="au50"><name><surname>KE</surname><given-names>Chang Wen</given-names></name><xref rid="aff2" ref-type="aff">b</xref></contrib><contrib contrib-type="author" id="au60"><name><surname>TAN</surname><given-names>Wen Jie</given-names></name><email>tanwj28@163.com</email><xref rid="aff1" ref-type="aff">a</xref><xref rid="cor1" ref-type="corresp">#</xref></contrib></contrib-group><aff id="aff1"><label>a</label>Key Laboratory of Medical Virology and Virus Disease, National Health and Family Planning Commission of the People's Republic of China; National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China</aff><aff id="aff2"><label>b</label>Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, Guangdong, China</aff><author-notes><corresp id="cor1"><label>#</label>Corresponding should be addressed to TAN Wen Jie, MD, PhD <email>tanwj28@163.com</email></corresp><fn id="fn1"><label>⁁</label><p id="cenpara20">WANG Wen Ling and WANG Hui Juan contributed equally to this work.</p></fn></author-notes><pub-date pub-type="pmc-release"><day>25</day><month>4</month><year>2016</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub"><month>3</month><year>2016</year></pub-date><pub-date pub-type="epub"><day>25</day><month>4</month><year>2016</year></pub-date><volume>29</volume><issue>3</issue><fpage>219</fpage><lpage>223</lpage><history><date date-type="received"><day>23</day><month>12</month><year>2015</year></date><date date-type="accepted"><day>2</day><month>3</month><year>2016</year></date></history><permissions><copyright-statement>© 2016 The Editorial Board of Biomedical and Environmental Sciences</copyright-statement><copyright-year>2016</copyright-year><license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p></license></permissions><abstract id="ceab10"><p>The first imported Middle East respiratory syndrome (MERS) case in China was identified in May 2015. We determined the kinetics of antibody (IgG and IgM) and neutralizing antibodies against MERS-coronavirus (MERS-CoV) in this case before discharge. Moreover, no seroconversion was found among 53 close contacts by anti-MERS IgG antibody enzyme-linked immunosorbent assay (ELISA) of paired serum samples. 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Prevention and Control Plan (2nd edition)</article-title><ext-link ext-link-type="uri" xlink:href="http://www.nhfpc.gov.cn/jkj/s3577/201506/f47f22f526144067898df6363d3e2d199.shtml" id="interrefs20">http://www.nhfpc.gov.cn/jkj/s3577/201506/f47f22f526144067898df6363d3e2d199.shtml</ext-link><comment>[2015-06-08].</comment></element-citation></ref><ref id="bib11"><label>11</label><element-citation publication-type="journal" id="sbref110"><person-group person-group-type="author"><name><surname>Gao</surname><given-names>J</given-names></name><name><surname>Song</surname><given-names>P</given-names></name></person-group><article-title>China upgrades surveillance and control measures of Middle East respiratory syndrome (MERS)</article-title><source>Biosci Trends</source><volume>9</volume><year>2015</year><fpage>203</fpage><lpage>204</lpage><pub-id pub-id-type="pmid">26063202</pub-id></element-citation></ref></ref-list><bio><p>Biographical notes of the first authors: WANG Wen Ling, female, born in 1973, PhD, Researcher, majoring in pathogen biology</p></bio><bio><p>WANG Hui Juan, female, born in 1972, Bachelor, Associate Chief Technician, majoring in pathogen biology.</p></bio><fn-group><fn id="d32e239"><p id="cenpara10">Funds from the <funding-source id="GS1">Nationl Health and Family Planning Commission of China</funding-source>: grants 2014ZX10004-001 and 2013ZX10004601.</p></fn></fn-group></back></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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