Infection control and MERS-CoV in health-care workers
Identifieur interne : 000812 ( Pmc/Corpus ); précédent : 000811; suivant : 000813Infection control and MERS-CoV in health-care workers
Auteurs : Alimuddin Zumla ; David S. HuiSource :
- Lancet (London, England) [ 0140-6736 ] ; 2014.
Url:
DOI: 10.1016/S0140-6736(14)60852-7
PubMed: 24857701
PubMed Central: 7138072
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Infection control and MERS-CoV in health-care workers</title><author><name sortKey="Zumla, Alimuddin" sort="Zumla, Alimuddin" uniqKey="Zumla A" first="Alimuddin" last="Zumla">Alimuddin Zumla</name><affiliation><nlm:aff id="aff1">Department of Infection, Division of Infection and Immunity, Centre for Clinical Microbiology, University College London, London, UK</nlm:aff></affiliation><affiliation><nlm:aff id="aff2">NIHR Biomedical Research Centre, University College London Hospitals, London, UK</nlm:aff></affiliation></author><author><name sortKey="Hui, David S" sort="Hui, David S" uniqKey="Hui D" first="David S" last="Hui">David S. Hui</name><affiliation><nlm:aff id="aff3">Department of Medicine and Therapeutics and Stanley Ho Center for Emerging Infectious Diseases, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24857701</idno><idno type="pmc">7138072</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138072</idno><idno type="RBID">PMC:7138072</idno><idno type="doi">10.1016/S0140-6736(14)60852-7</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">000812</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000812</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Infection control and MERS-CoV in health-care workers</title><author><name sortKey="Zumla, Alimuddin" sort="Zumla, Alimuddin" uniqKey="Zumla A" first="Alimuddin" last="Zumla">Alimuddin Zumla</name><affiliation><nlm:aff id="aff1">Department of Infection, Division of Infection and Immunity, Centre for Clinical Microbiology, University College London, London, UK</nlm:aff></affiliation><affiliation><nlm:aff id="aff2">NIHR Biomedical Research Centre, University College London Hospitals, London, UK</nlm:aff></affiliation></author><author><name sortKey="Hui, David S" sort="Hui, David S" uniqKey="Hui D" first="David S" last="Hui">David S. Hui</name><affiliation><nlm:aff id="aff3">Department of Medicine and Therapeutics and Stanley Ho Center for Emerging Infectious Diseases, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong</nlm:aff></affiliation></author></analytic><series><title level="j">Lancet (London, England)</title><idno type="ISSN">0140-6736</idno><idno type="eISSN">1474-547X</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Zaki, Am" uniqKey="Zaki A">AM Zaki</name></author><author><name sortKey="Van Boheemen, S" uniqKey="Van Boheemen S">S van Boheemen</name></author><author><name sortKey="Bestebroer, Tm" uniqKey="Bestebroer T">TM Bestebroer</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Hijawi, B" uniqKey="Hijawi B">B Hijawi</name></author><author><name sortKey="Abdallat, M" uniqKey="Abdallat M">M Abdallat</name></author><author><name sortKey="Sayaydeh, A" uniqKey="Sayaydeh A">A Sayaydeh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Assiri, A" uniqKey="Assiri A">A Assiri</name></author><author><name sortKey="Mcgeer, A" uniqKey="Mcgeer A">A McGeer</name></author><author><name sortKey="Perl, Tm" uniqKey="Perl T">TM Perl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hui, Ds" uniqKey="Hui D">DS Hui</name></author><author><name sortKey="Memish, Za" uniqKey="Memish Z">ZA Memish</name></author><author><name sortKey="Zumla, A" uniqKey="Zumla A">A Zumla</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Seto, Wh" uniqKey="Seto W">WH Seto</name></author><author><name sortKey="Conly, Jm" uniqKey="Conly J">JM Conly</name></author><author><name sortKey="Pessoa Silva, Cl" uniqKey="Pessoa Silva C">CL Pessoa-Silva</name></author><author><name sortKey="Malik, M" uniqKey="Malik M">M Malik</name></author><author><name sortKey="Eremin, S" uniqKey="Eremin S">S Eremin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Riley, S" uniqKey="Riley S">S Riley</name></author><author><name sortKey="Fraser, C" uniqKey="Fraser C">C Fraser</name></author><author><name sortKey="Donnelly, Ca" uniqKey="Donnelly C">CA Donnelly</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, N" uniqKey="Lee N">N Lee</name></author><author><name sortKey="Hui, Ds" uniqKey="Hui D">DS Hui</name></author><author><name sortKey="Wu, A" uniqKey="Wu A">A Wu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tomlinson, B" uniqKey="Tomlinson B">B Tomlinson</name></author><author><name sortKey="Cockram, C" uniqKey="Cockram C">C Cockram</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Booth, Tf" uniqKey="Booth T">TF Booth</name></author><author><name sortKey="Kournikakis, B" uniqKey="Kournikakis B">B Kournikakis</name></author><author><name sortKey="Bastien, N" uniqKey="Bastien N">N Bastien</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yu, It" uniqKey="Yu I">IT Yu</name></author><author><name sortKey="Xie, Zh" uniqKey="Xie Z">ZH Xie</name></author><author><name sortKey="Tsoi, Kk" uniqKey="Tsoi K">KK Tsoi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tran, K" uniqKey="Tran K">K Tran</name></author><author><name sortKey="Cimon, K" uniqKey="Cimon K">K Cimon</name></author><author><name sortKey="Severn, M" uniqKey="Severn M">M Severn</name></author><author><name sortKey="Pessoa Silva, Cl" uniqKey="Pessoa Silva C">CL Pessoa-Silva</name></author><author><name sortKey="Conly, J" uniqKey="Conly J">J Conly</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Siegel, Jd" uniqKey="Siegel J">JD Siegel</name></author><author><name sortKey="Rhinehart, E" uniqKey="Rhinehart E">E Rhinehart</name></author><author><name sortKey="Jackson, M" uniqKey="Jackson M">M Jackson</name></author><author><name sortKey="Chiarello, L" uniqKey="Chiarello L">L Chiarello</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Sehulster, L" uniqKey="Sehulster L">L Sehulster</name></author><author><name sortKey="Chinn, Ry" uniqKey="Chinn R">RY Chinn</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="discussion"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Lancet</journal-id><journal-id journal-id-type="iso-abbrev">Lancet</journal-id><journal-title-group><journal-title>Lancet (London, England)</journal-title></journal-title-group><issn pub-type="ppub">0140-6736</issn><issn pub-type="epub">1474-547X</issn><publisher><publisher-name>Elsevier Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">24857701</article-id><article-id pub-id-type="pmc">7138072</article-id><article-id pub-id-type="publisher-id">S0140-6736(14)60852-7</article-id><article-id pub-id-type="doi">10.1016/S0140-6736(14)60852-7</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Infection control and MERS-CoV in health-care workers</article-title></title-group><contrib-group><contrib contrib-type="author" id="au10"><name><surname>Zumla</surname><given-names>Alimuddin</given-names></name><xref rid="aff1" ref-type="aff">a</xref><xref rid="aff2" ref-type="aff">b</xref></contrib><contrib contrib-type="author" id="au20"><name><surname>Hui</surname><given-names>David S</given-names></name><email>dschui@cuhk.edu.hk</email><xref rid="aff3" ref-type="aff">c</xref></contrib></contrib-group><aff id="aff1"><label>a</label>Department of Infection, Division of Infection and Immunity, Centre for Clinical Microbiology, University College London, London, UK</aff><aff id="aff2"><label>b</label>NIHR Biomedical Research Centre, University College London Hospitals, London, UK</aff><aff id="aff3"><label>c</label>Department of Medicine and Therapeutics and Stanley Ho Center for Emerging Infectious Diseases, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong</aff><pub-date pub-type="pmc-release"><day>20</day><month>5</month><year>2014</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub" iso-8601-date="2014-06-06"><season>31 May-6 June</season><year>2014</year></pub-date><pub-date pub-type="epub"><day>20</day><month>5</month><year>2014</year></pub-date><volume>383</volume><issue>9932</issue><fpage>1869</fpage><lpage>1871</lpage><permissions><copyright-statement>Copyright © 2014 Elsevier Ltd. All rights reserved.</copyright-statement><copyright-year>2014</copyright-year><copyright-holder>Elsevier Ltd</copyright-holder><license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p></license></permissions></article-meta></front><body><p id="para10">The recent exponential rise in the number of reported cases of Middle East respiratory syndrome coronavirus (MERS-CoV) is of major global concern. The Fifth Meeting of the International Health Regulations Emergency Committee concerning MERS-CoV was convened on May 13, 2014, by WHO's Director-General and concluded that, although the seriousness of the situation had increased, there was no evidence of sustained human-to-human transmission and that conditions for a Public Health Emergency of International Concern have not yet been met.<xref rid="bib1" ref-type="bibr"><sup>1</sup></xref></p><p id="para20">MERS-CoV was first reported in September, 2012, when a novel β coronavirus was isolated from a Saudi Arabian patient in Jeddah, who had died of severe pneumonia and multiple organ failure in June, 2012.<xref rid="bib2" ref-type="bibr"><sup>2</sup></xref> More recently, a large number of MERS-CoV cases have been reported from Saudi Arabia and for the first time cases have been detected in Malaysia, Philippines, Greece, Egypt, Netherlands, and the USA. There have been a total of 572 cases of MERS-CoV infection reported to WHO globally as of May 15, 2014, with 173 deaths (30% mortality rate).<xref rid="bib3" ref-type="bibr"><sup>3</sup></xref></p><p id="para60"><fig id="f10"><graphic xlink:href="fx1_lrg"></graphic><permissions><copyright-statement>© 2014 Science Photo Library</copyright-statement><copyright-year>2014</copyright-year><license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p></license></permissions></fig></p><p id="para30">The large number of MERS-CoV cases (229 cases) reported between April 11, 2014, and May 4, 2014, by Saudi Arabia were probably seasonal (related to the camel birthing season), reminiscent of the clusters of hospital cases that were previously confirmed in a hospital in Jordan in April, 2012,<xref rid="bib4" ref-type="bibr"><sup>4</sup></xref> which involved haemodialysis units within hospitals in Al Hasa in April and May, 2013.<xref rid="bib5" ref-type="bibr"><sup>5</sup></xref> Sequencing of the MERS-CoV isolates from the Jeddah outbreak has shown no substantial genetic changes.<xref rid="bib1" ref-type="bibr"><sup>1</sup></xref> The WHO Emergency Committee concluded that the increase in cases reported among health-care workers from hospitals in Jeddah was amplified due to overcrowding and inadequate infection control measures.<xref rid="bib1" ref-type="bibr">1</xref>, <xref rid="bib3" ref-type="bibr">3</xref></p><p id="para40">Acute viral respiratory tract infections, such as severe acute respiratory syndrome (SARS) and MERS, are predominantly spread by large respiratory droplets (≥10 μm in diameter) during coughing and sneezing, whereas contact with fomite (including hand contamination with subsequent self-inoculation) might be another potential route of transmission.<xref rid="bib6" ref-type="bibr">6</xref>, <xref rid="bib7" ref-type="bibr">7</xref> The SARS outbreak in 2003 provided good lessons for the evaluation of environmental influences on the aerosol transmission of communicable respiratory diseases and the importance of good infection control measures in the prevention of nosocomial infections. One intriguing aspect of the 2003 SARS epidemic was the occurrence of super-spreading events, which accounted for 71·1% and 74·8% of SARS cases in Hong Kong and Singapore, respectively.<xref rid="bib8" ref-type="bibr"><sup>8</sup></xref> During the SARS outbreak in 2003, SARS-coronavirus (CoV) was moderately transmissible, with 2·7 secondary infections for every index case.<xref rid="bib8" ref-type="bibr"><sup>8</sup></xref> However, infectivity was substantially increased when coupled with environmental factors: 138 patients, many of whom were health-care workers, were infected within 2 weeks as a result of exposure to one patient with community-acquired pneumonia who was admitted to a general medical ward.<xref rid="bib9" ref-type="bibr"><sup>9</sup></xref> This super-spreading event seemed to be related to overcrowding and poor ventilation in the dry air-conditioned hospital ward, together with some contribution by the use of a jet nebuliser for the index case.<xref rid="bib10" ref-type="bibr"><sup>10</sup></xref> Evidence of airborne transmission of SARS-CoV was also supported by positive air samples of the virus obtained from a hospital room occupied by a patient with SARS in Toronto, Canada.<xref rid="bib11" ref-type="bibr"><sup>11</sup></xref></p><p id="para50">On the basis of analysis of data in a case-control study that involved 124 medical wards in 26 hospitals in Guangzhou, China, and Hong Kong, the risk factors for super-spreading events of SARS-CoV in the hospital setting were: close separation between beds of less than 1 m; performance of resuscitation; staff working while experiencing symptoms; and patients requiring oxygen or non-invasive ventilation therapy.<xref rid="bib12" ref-type="bibr"><sup>12</sup></xref> This study also showed that the availability of washing or changing facilities for health-care staff was a protective factor.<xref rid="bib12" ref-type="bibr"><sup>12</sup></xref> These findings have important clinical implications in the prevention of nosocomial infections of MERS-CoV in health-care facilities in the Middle East.</p><p id="para70">A systematic review of five case-control and five retrospective cohort studies identified tracheal intubation, tracheotomy, and manual ventilation before intubation as procedures associated with risk of transmission of SARS-CoV to health-care workers.<xref rid="bib13" ref-type="bibr"><sup>13</sup></xref> Opportunistic airborne transmission might occur through fine particle aerosols as an efficient means of propagation under special environmental conditions, such as with aerosol-generating procedures in a ward environment with poor ventilation and insufficient air changes.<xref rid="bib7" ref-type="bibr"><sup>7</sup></xref></p><p id="para80">The main infection prevention and control measures for managing acute viral respiratory tract infections are simple and well documented: droplet precaution (wearing a surgical mask within 1 m of the patient) and contact precaution (wearing gown and gloves on entering the room and removing them on leaving).<xref rid="bib14" ref-type="bibr"><sup>14</sup></xref> Droplet precautions should be added to standard precautions for patients with symptoms of acute respiratory infection. Contact precautions and eye protection should be added when caring for probable or confirmed cases of MERS-CoV infection. Airborne precautions should be applied when performing aerosol-generating procedures.<xref rid="bib3" ref-type="bibr">3</xref>, <xref rid="bib6" ref-type="bibr">6</xref>, <xref rid="bib7" ref-type="bibr">7</xref>, <xref rid="bib15" ref-type="bibr">15</xref> To reduce room contamination in the hospital setting, major health organisations have recommended the application of a minimum room ventilation rate of six air changes per hour in existing facility, whereas a higher ventilation rate of 12 air changes per hour is recommended for new or renovated construction, especially when caring for patients receiving mechanical ventilation and during aerosol-generating procedures.<xref rid="bib16" ref-type="bibr">16</xref>, <xref rid="bib17" ref-type="bibr">17</xref> Infection source and engineering control, including avoidance of aerosol generation with appropriate airborne precautions, and improvement of ventilation design in hospital wards warrant serious consideration for the prevention of nosocomial outbreaks. The MERS-CoV outbreak in Jeddah, and the increasing number of health-care workers acquiring the infection as a result of poor infection control measures, remind us of the need to go back to the basics of infection control to help prevent MERS-CoV infection in health-care workers.</p><p id="para80a"><boxed-text id="cetextbox10"><p id="para80b"><bold>This online publication has been corrected. The corrected version first appeared at thelancet.com on May 21, 2014</bold></p></boxed-text></p></body><back><ref-list id="bibl10"><title>References</title><ref id="bib1"><label>1</label><element-citation publication-type="other" id="sbref10"><person-group person-group-type="author"><collab>WHO</collab></person-group><article-title>WHO statement on the Fifth Meeting of the IHR Emergency Committee concerning MERS-CoV</article-title><ext-link ext-link-type="uri" xlink:href="http://www.who.int/mediacentre/news/statements/2014/mers-20140514/en/" id="interrefs10">http://www.who.int/mediacentre/news/statements/2014/mers-20140514/en/</ext-link><year>May 14, 2014</year><comment>(accessed May 15, 2014).</comment></element-citation></ref><ref id="bib2"><label>2</label><element-citation publication-type="journal" id="sbref20"><person-group person-group-type="author"><name><surname>Zaki</surname><given-names>AM</given-names></name><name><surname>van Boheemen</surname><given-names>S</given-names></name><name><surname>Bestebroer</surname><given-names>TM</given-names></name></person-group><article-title>Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia</article-title><source>N Engl J Med</source><volume>367</volume><year>2012</year><fpage>1814</fpage><lpage>1820</lpage><pub-id pub-id-type="pmid">23075143</pub-id></element-citation></ref><ref id="bib3"><label>3</label><element-citation publication-type="other" id="sbref30"><person-group person-group-type="author"><collab>WHO</collab></person-group><article-title>Global alert and response. Middle East respiratory syndrome coronavirus (MERS-CoV)—update</article-title><ext-link ext-link-type="uri" xlink:href="http://www.who.int/csr/don/2014_05_15_mers/en/" id="interrefs20">http://www.who.int/csr/don/2014_05_15_mers/en/</ext-link><year>May 15, 2014</year><comment>(accessed May 19, 2014).</comment></element-citation></ref><ref id="bib4"><label>4</label><element-citation publication-type="journal" id="sbref40"><person-group person-group-type="author"><name><surname>Hijawi</surname><given-names>B</given-names></name><name><surname>Abdallat</surname><given-names>M</given-names></name><name><surname>Sayaydeh</surname><given-names>A</given-names></name></person-group><article-title>Novel coronavirus infections in Jordan, April 2012: epidemiological findings from a retrospective investigation</article-title><source>East Mediterr Health J</source><volume>19</volume><issue>suppl 1</issue><year>2013</year><fpage>S12</fpage><lpage>S18</lpage><pub-id pub-id-type="pmid">23888790</pub-id></element-citation></ref><ref id="bib5"><label>5</label><element-citation publication-type="journal" id="sbref50"><person-group person-group-type="author"><name><surname>Assiri</surname><given-names>A</given-names></name><name><surname>McGeer</surname><given-names>A</given-names></name><name><surname>Perl</surname><given-names>TM</given-names></name></person-group><article-title>Hospital outbreak of Middle East respiratory syndrome coronavirus</article-title><source>N Engl J Med</source><volume>369</volume><year>2013</year><fpage>407</fpage><lpage>416</lpage><pub-id pub-id-type="pmid">23782161</pub-id></element-citation></ref><ref id="bib6"><label>6</label><element-citation publication-type="journal" id="sbref60"><person-group person-group-type="author"><name><surname>Hui</surname><given-names>DS</given-names></name><name><surname>Memish</surname><given-names>ZA</given-names></name><name><surname>Zumla</surname><given-names>A</given-names></name></person-group><article-title>Severe acute respiratory syndrome vs the Middle East respiratory syndrome</article-title><source>Curr Opin Pulm Med</source><volume>20</volume><year>2014</year><fpage>233</fpage><lpage>241</lpage><pub-id pub-id-type="pmid">24626235</pub-id></element-citation></ref><ref id="bib7"><label>7</label><element-citation publication-type="journal" id="sbref70"><person-group person-group-type="author"><name><surname>Seto</surname><given-names>WH</given-names></name><name><surname>Conly</surname><given-names>JM</given-names></name><name><surname>Pessoa-Silva</surname><given-names>CL</given-names></name><name><surname>Malik</surname><given-names>M</given-names></name><name><surname>Eremin</surname><given-names>S</given-names></name></person-group><article-title>Infection prevention and control measures for acute respiratory infections in healthcare settings: an update</article-title><source>East Mediterr Health J</source><volume>19</volume><issue>suppl 1</issue><year>2013</year><fpage>S39</fpage><lpage>47</lpage><pub-id pub-id-type="pmid">23888794</pub-id></element-citation></ref><ref id="bib8"><label>8</label><element-citation publication-type="journal" id="sbref80"><person-group person-group-type="author"><name><surname>Riley</surname><given-names>S</given-names></name><name><surname>Fraser</surname><given-names>C</given-names></name><name><surname>Donnelly</surname><given-names>CA</given-names></name></person-group><article-title>Transmission dynamics of the etiological agent of SARS in Hong Kong: impact of public health interventions</article-title><source>Science</source><volume>300</volume><year>2003</year><fpage>1961</fpage><lpage>1966</lpage><pub-id pub-id-type="pmid">12766206</pub-id></element-citation></ref><ref id="bib9"><label>9</label><element-citation publication-type="journal" id="sbref90"><person-group person-group-type="author"><name><surname>Lee</surname><given-names>N</given-names></name><name><surname>Hui</surname><given-names>DS</given-names></name><name><surname>Wu</surname><given-names>A</given-names></name></person-group><article-title>A major outbreak of severe acute respiratory syndrome in Hong Kong</article-title><source>N Engl J Med</source><volume>348</volume><year>2003</year><fpage>1986</fpage><lpage>1994</lpage><pub-id pub-id-type="pmid">12682352</pub-id></element-citation></ref><ref id="bib10"><label>10</label><element-citation publication-type="journal" id="sbref100"><person-group person-group-type="author"><name><surname>Tomlinson</surname><given-names>B</given-names></name><name><surname>Cockram</surname><given-names>C</given-names></name></person-group><article-title>SARS: experience at Prince of Wales Hospital, Hong Kong</article-title><source>Lancet</source><volume>361</volume><year>2003</year><fpage>1486</fpage><lpage>1487</lpage><pub-id pub-id-type="pmid">12737853</pub-id></element-citation></ref><ref id="bib11"><label>11</label><element-citation publication-type="journal" id="sbref110"><person-group person-group-type="author"><name><surname>Booth</surname><given-names>TF</given-names></name><name><surname>Kournikakis</surname><given-names>B</given-names></name><name><surname>Bastien</surname><given-names>N</given-names></name></person-group><article-title>Detection of airborne severe acute respiratory syndrome (SARS) coronavirus and environmental contamination in SARS outbreak units</article-title><source>J Infect Dis</source><volume>191</volume><year>2005</year><fpage>1472</fpage><lpage>1477</lpage><pub-id pub-id-type="pmid">15809906</pub-id></element-citation></ref><ref id="bib12"><label>12</label><element-citation publication-type="journal" id="sbref120"><person-group person-group-type="author"><name><surname>Yu</surname><given-names>IT</given-names></name><name><surname>Xie</surname><given-names>ZH</given-names></name><name><surname>Tsoi</surname><given-names>KK</given-names></name></person-group><article-title>Why did outbreaks of severe acute respiratory syndrome occur in some hospital wards but not in others?</article-title><source>Clin Infect Dis</source><volume>44</volume><year>2007</year><fpage>1017</fpage><lpage>1025</lpage><pub-id pub-id-type="pmid">17366443</pub-id></element-citation></ref><ref id="bib13"><label>13</label><element-citation publication-type="journal" id="sbref130"><person-group person-group-type="author"><name><surname>Tran</surname><given-names>K</given-names></name><name><surname>Cimon</surname><given-names>K</given-names></name><name><surname>Severn</surname><given-names>M</given-names></name><name><surname>Pessoa-Silva</surname><given-names>CL</given-names></name><name><surname>Conly</surname><given-names>J</given-names></name></person-group><article-title>Aerosol generating procedures and risk of transmission of acute respiratory infections to healthcare workers: a systematic review</article-title><source>PLoS One</source><volume>7</volume><year>2012</year><fpage>e35797</fpage><pub-id pub-id-type="pmid">22563403</pub-id></element-citation></ref><ref id="bib14"><label>14</label><element-citation publication-type="other" id="sbref140"><person-group person-group-type="author"><name><surname>Siegel</surname><given-names>JD</given-names></name><name><surname>Rhinehart</surname><given-names>E</given-names></name><name><surname>Jackson</surname><given-names>M</given-names></name><name><surname>Chiarello</surname><given-names>L</given-names></name><collab>the Healthcare Infection Control Practices Advisory Committee</collab></person-group><article-title>2007 guideline for isolation precautions: preventing transmission of infectious agents in healthcare settings. 2007</article-title><ext-link ext-link-type="uri" xlink:href="http://www.cdc.gov/hicpac/2007IP/2007isolationPrecautions.html" id="interrefs30">http://www.cdc.gov/hicpac/2007IP/2007isolationPrecautions.html</ext-link><comment>(accessed May 18, 2014).</comment></element-citation></ref><ref id="bib15"><label>15</label><element-citation publication-type="other" id="sbref150"><person-group person-group-type="author"><collab>CDC</collab></person-group><article-title>Interim infection prevention and control recommendations for hospitalized patients with Middle East respiratory syndrome coronavirus (MERS-CoV)</article-title><ext-link ext-link-type="uri" xlink:href="http://www.cdc.gov/coronavirus/mers/infection-prevention-control.html#infection-prevention" id="interrefs40">http://www.cdc.gov/coronavirus/mers/infection-prevention-control.html#infection-prevention</ext-link><year>May 15, 2014</year><comment>(accessed May 17, 2014).</comment></element-citation></ref><ref id="bib16"><label>16</label><element-citation publication-type="book" id="sbref160"><person-group person-group-type="author"><collab>WHO</collab></person-group><source>WHO guidelines on natural ventilation for infection control in health-care settings</source><year>2009</year><publisher-name>World Health Organization</publisher-name><publisher-loc>Geneva</publisher-loc><ext-link ext-link-type="uri" xlink:href="http://whqlibdoc.who.int/publications/2009/9789241547857_eng.pdf" id="interrefs50">http://whqlibdoc.who.int/publications/2009/9789241547857_eng.pdf</ext-link><comment>(accessed May 12, 2104).</comment></element-citation></ref><ref id="bib17"><label>17</label><element-citation publication-type="journal" id="sbref170"><person-group person-group-type="author"><name><surname>Sehulster</surname><given-names>L</given-names></name><name><surname>Chinn</surname><given-names>RY</given-names></name><collab>CDC</collab><collab>HICPAC</collab></person-group><article-title>Guidelines for environmental infection control in health-care facilities. Recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee (HICPAC)</article-title><source>MMWR Recomm Rep</source><volume>52</volume><issue>RR-10</issue><year>2003</year><fpage>1</fpage><lpage>42</lpage></element-citation></ref></ref-list><ack><p>AZ and DSH serve on the Scientific Advisory Committee of the Saudi Ministry of Health Global Centre for Mass Gathering Medicine. We declare no competing interests.</p></ack></back></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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