Influenza virus emitted by naturally-infected hosts in a healthcare setting
Identifieur interne : 000E24 ( Pmc/Checkpoint ); précédent : 000E23; suivant : 000E25Influenza virus emitted by naturally-infected hosts in a healthcare setting
Auteurs : Samira Mubareka [Canada] ; Andrea Granados [Canada] ; Ushma Naik [Canada] ; Ilyse Darwish [Canada] ; Todd A. Cutts [Canada] ; George Astrakianakis [Canada] ; Jonathan B. Gubbay [Canada] ; Adriana Peci [Canada] ; James A. Scott [Canada]Source :
- Journal of Clinical Virology [ 1386-6532 ] ; 2015.
Abstract
This pilot study examined the viral content of bioaerosols emitted by patients with laboratory-confirmed influenza. Nine out of fifteen patients emitted variable amounts of viral RNA. Patients with influenza may emit virus into the air which disperses >1 m and may reach the breathing zone of a healthcare worker.
Url:
DOI: 10.1016/j.jcv.2015.11.002
PubMed: 26590688
PubMed Central: 7106343
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Influenza virus emitted by naturally-infected hosts in a healthcare setting</title><author><name sortKey="Mubareka, Samira" sort="Mubareka, Samira" uniqKey="Mubareka S" first="Samira" last="Mubareka">Samira Mubareka</name><affiliation wicri:level="1"><nlm:aff id="aff0005">Sunnybrook Research Institute, 2075 Bayview Avenue suite B103, Toronto, ON M4N 3M1, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Sunnybrook Research Institute, 2075 Bayview Avenue suite B103, Toronto, ON M4N 3M1</wicri:regionArea><wicri:noRegion>ON M4N 3M1</wicri:noRegion></affiliation></author><author><name sortKey="Granados, Andrea" sort="Granados, Andrea" uniqKey="Granados A" first="Andrea" last="Granados">Andrea Granados</name><affiliation wicri:level="1"><nlm:aff id="aff0010">Public Health Ontario, 661 University Avenue, Suite 1701, Toronto, ON M5G 1M1, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Public Health Ontario, 661 University Avenue, Suite 1701, Toronto, ON M5G 1M1</wicri:regionArea><wicri:noRegion>ON M5G 1M1</wicri:noRegion></affiliation></author><author><name sortKey="Naik, Ushma" sort="Naik, Ushma" uniqKey="Naik U" first="Ushma" last="Naik">Ushma Naik</name><affiliation wicri:level="1"><nlm:aff id="aff0015">Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON M4N 3M1, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON M4N 3M1</wicri:regionArea><wicri:noRegion>ON M4N 3M1</wicri:noRegion></affiliation></author><author><name sortKey="Darwish, Ilyse" sort="Darwish, Ilyse" uniqKey="Darwish I" first="Ilyse" last="Darwish">Ilyse Darwish</name><affiliation wicri:level="1"><nlm:aff id="aff0015">Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON M4N 3M1, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON M4N 3M1</wicri:regionArea><wicri:noRegion>ON M4N 3M1</wicri:noRegion></affiliation></author><author><name sortKey="Cutts, Todd A" sort="Cutts, Todd A" uniqKey="Cutts T" first="Todd A." last="Cutts">Todd A. Cutts</name><affiliation wicri:level="1"><nlm:aff id="aff0020">National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, MB R3E 3R2, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, MB R3E 3R2</wicri:regionArea><wicri:noRegion>MB R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Astrakianakis, George" sort="Astrakianakis, George" uniqKey="Astrakianakis G" first="George" last="Astrakianakis">George Astrakianakis</name><affiliation wicri:level="1"><nlm:aff id="aff0025">School of Population and Public Health, University of British Columbia, Rm 366C 2206 East Mall, Vancouver, BC V6T 1Z3, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>School of Population and Public Health, University of British Columbia, Rm 366C 2206 East Mall, Vancouver, BC V6T 1Z3</wicri:regionArea><wicri:noRegion>BC V6T 1Z3</wicri:noRegion></affiliation></author><author><name sortKey="Gubbay, Jonathan B" sort="Gubbay, Jonathan B" uniqKey="Gubbay J" first="Jonathan B." last="Gubbay">Jonathan B. Gubbay</name><affiliation wicri:level="1"><nlm:aff id="aff0010">Public Health Ontario, 661 University Avenue, Suite 1701, Toronto, ON M5G 1M1, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Public Health Ontario, 661 University Avenue, Suite 1701, Toronto, ON M5G 1M1</wicri:regionArea><wicri:noRegion>ON M5G 1M1</wicri:noRegion></affiliation></author><author><name sortKey="Peci, Adriana" sort="Peci, Adriana" uniqKey="Peci A" first="Adriana" last="Peci">Adriana Peci</name><affiliation wicri:level="1"><nlm:aff id="aff0010">Public Health Ontario, 661 University Avenue, Suite 1701, Toronto, ON M5G 1M1, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Public Health Ontario, 661 University Avenue, Suite 1701, Toronto, ON M5G 1M1</wicri:regionArea><wicri:noRegion>ON M5G 1M1</wicri:noRegion></affiliation></author><author><name sortKey="Scott, James A" sort="Scott, James A" uniqKey="Scott J" first="James A." last="Scott">James A. Scott</name><affiliation wicri:level="4"><nlm:aff id="aff0030">Division of Occupational and Environmental Health, Dalla Lana School of Public Health, University of Toronto, 223 College Street, Toronto, ON M5T 1R4, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Occupational and Environmental Health, Dalla Lana School of Public Health, University of Toronto, 223 College Street, Toronto, ON M5T 1R4</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26590688</idno><idno type="pmc">7106343</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106343</idno><idno type="RBID">PMC:7106343</idno><idno type="doi">10.1016/j.jcv.2015.11.002</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">000708</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000708</idno><idno type="wicri:Area/Pmc/Curation">000708</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000708</idno><idno type="wicri:Area/Pmc/Checkpoint">000E24</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000E24</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Influenza virus emitted by naturally-infected hosts in a healthcare setting</title><author><name sortKey="Mubareka, Samira" sort="Mubareka, Samira" uniqKey="Mubareka S" first="Samira" last="Mubareka">Samira Mubareka</name><affiliation wicri:level="1"><nlm:aff id="aff0005">Sunnybrook Research Institute, 2075 Bayview Avenue suite B103, Toronto, ON M4N 3M1, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Sunnybrook Research Institute, 2075 Bayview Avenue suite B103, Toronto, ON M4N 3M1</wicri:regionArea><wicri:noRegion>ON M4N 3M1</wicri:noRegion></affiliation></author><author><name sortKey="Granados, Andrea" sort="Granados, Andrea" uniqKey="Granados A" first="Andrea" last="Granados">Andrea Granados</name><affiliation wicri:level="1"><nlm:aff id="aff0010">Public Health Ontario, 661 University Avenue, Suite 1701, Toronto, ON M5G 1M1, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Public Health Ontario, 661 University Avenue, Suite 1701, Toronto, ON M5G 1M1</wicri:regionArea><wicri:noRegion>ON M5G 1M1</wicri:noRegion></affiliation></author><author><name sortKey="Naik, Ushma" sort="Naik, Ushma" uniqKey="Naik U" first="Ushma" last="Naik">Ushma Naik</name><affiliation wicri:level="1"><nlm:aff id="aff0015">Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON M4N 3M1, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON M4N 3M1</wicri:regionArea><wicri:noRegion>ON M4N 3M1</wicri:noRegion></affiliation></author><author><name sortKey="Darwish, Ilyse" sort="Darwish, Ilyse" uniqKey="Darwish I" first="Ilyse" last="Darwish">Ilyse Darwish</name><affiliation wicri:level="1"><nlm:aff id="aff0015">Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON M4N 3M1, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON M4N 3M1</wicri:regionArea><wicri:noRegion>ON M4N 3M1</wicri:noRegion></affiliation></author><author><name sortKey="Cutts, Todd A" sort="Cutts, Todd A" uniqKey="Cutts T" first="Todd A." last="Cutts">Todd A. Cutts</name><affiliation wicri:level="1"><nlm:aff id="aff0020">National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, MB R3E 3R2, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, MB R3E 3R2</wicri:regionArea><wicri:noRegion>MB R3E 3R2</wicri:noRegion></affiliation></author><author><name sortKey="Astrakianakis, George" sort="Astrakianakis, George" uniqKey="Astrakianakis G" first="George" last="Astrakianakis">George Astrakianakis</name><affiliation wicri:level="1"><nlm:aff id="aff0025">School of Population and Public Health, University of British Columbia, Rm 366C 2206 East Mall, Vancouver, BC V6T 1Z3, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>School of Population and Public Health, University of British Columbia, Rm 366C 2206 East Mall, Vancouver, BC V6T 1Z3</wicri:regionArea><wicri:noRegion>BC V6T 1Z3</wicri:noRegion></affiliation></author><author><name sortKey="Gubbay, Jonathan B" sort="Gubbay, Jonathan B" uniqKey="Gubbay J" first="Jonathan B." last="Gubbay">Jonathan B. Gubbay</name><affiliation wicri:level="1"><nlm:aff id="aff0010">Public Health Ontario, 661 University Avenue, Suite 1701, Toronto, ON M5G 1M1, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Public Health Ontario, 661 University Avenue, Suite 1701, Toronto, ON M5G 1M1</wicri:regionArea><wicri:noRegion>ON M5G 1M1</wicri:noRegion></affiliation></author><author><name sortKey="Peci, Adriana" sort="Peci, Adriana" uniqKey="Peci A" first="Adriana" last="Peci">Adriana Peci</name><affiliation wicri:level="1"><nlm:aff id="aff0010">Public Health Ontario, 661 University Avenue, Suite 1701, Toronto, ON M5G 1M1, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Public Health Ontario, 661 University Avenue, Suite 1701, Toronto, ON M5G 1M1</wicri:regionArea><wicri:noRegion>ON M5G 1M1</wicri:noRegion></affiliation></author><author><name sortKey="Scott, James A" sort="Scott, James A" uniqKey="Scott J" first="James A." last="Scott">James A. Scott</name><affiliation wicri:level="4"><nlm:aff id="aff0030">Division of Occupational and Environmental Health, Dalla Lana School of Public Health, University of Toronto, 223 College Street, Toronto, ON M5T 1R4, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Occupational and Environmental Health, Dalla Lana School of Public Health, University of Toronto, 223 College Street, Toronto, ON M5T 1R4</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author></analytic><series><title level="j">Journal of Clinical Virology</title><idno type="ISSN">1386-6532</idno><idno type="eISSN">1873-5967</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Highlights</title><p><list list-type="simple" id="lis0005"><list-item id="lsti0005"><label>•</label><p id="par0005">This pilot study examined the viral content of bioaerosols emitted by patients with laboratory-confirmed influenza.</p></list-item><list-item id="lsti0010"><label>•</label><p id="par0010">Nine out of fifteen patients emitted variable amounts of viral RNA.</p></list-item><list-item id="lsti0015"><label>•</label><p id="par0015">Patients with influenza may emit virus into the air which disperses >1 m and may reach the breathing zone of a healthcare worker.</p></list-item></list></p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Assiri, A" uniqKey="Assiri A">A. Assiri</name></author><author><name sortKey="Mcgeer, A" uniqKey="Mcgeer A">A. McGeer</name></author><author><name sortKey="Perl, T M" uniqKey="Perl T">T.M. Perl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thangavel, R R" uniqKey="Thangavel R">R.R. Thangavel</name></author><author><name sortKey="Bouvier, N M" uniqKey="Bouvier N">N.M. Bouvier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lowen, A C" uniqKey="Lowen A">A.C. Lowen</name></author><author><name sortKey="Bouvier, N M" uniqKey="Bouvier N">N.M. Bouvier</name></author><author><name sortKey="Steel, J" uniqKey="Steel J">J. Steel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Herfst, S" uniqKey="Herfst S">S. Herfst</name></author><author><name sortKey="Schrauwen, E J" uniqKey="Schrauwen E">E.J. Schrauwen</name></author><author><name sortKey="Linster, M" uniqKey="Linster M">M. Linster</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Imai, M" uniqKey="Imai M">M. Imai</name></author><author><name sortKey="Watanabe, T" uniqKey="Watanabe T">T. Watanabe</name></author><author><name sortKey="Hatta, M" uniqKey="Hatta M">M. Hatta</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Blachere, F M" uniqKey="Blachere F">F.M. Blachere</name></author><author><name sortKey="Lindsley, W G" uniqKey="Lindsley W">W.G. Lindsley</name></author><author><name sortKey="Pearce, T A" uniqKey="Pearce T">T.A. Pearce</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lindsley, W G" uniqKey="Lindsley W">W.G. Lindsley</name></author><author><name sortKey="Blachere, F M" uniqKey="Blachere F">F.M. Blachere</name></author><author><name sortKey="Davis, K A" uniqKey="Davis K">K.A. Davis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bischoff, W E" uniqKey="Bischoff W">W.E. Bischoff</name></author><author><name sortKey="Swett, K" uniqKey="Swett K">K. Swett</name></author><author><name sortKey="Leng, I" uniqKey="Leng I">I. Leng</name></author><author><name sortKey="Peters, T R" uniqKey="Peters T">T.R. Peters</name></author></analytic></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><pmc article-type="brief-report"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Clin Virol</journal-id><journal-id journal-id-type="iso-abbrev">J. Clin. Virol</journal-id><journal-title-group><journal-title>Journal of Clinical Virology</journal-title></journal-title-group><issn pub-type="ppub">1386-6532</issn><issn pub-type="epub">1873-5967</issn><publisher><publisher-name>Elsevier B.V.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">26590688</article-id><article-id pub-id-type="pmc">7106343</article-id><article-id pub-id-type="publisher-id">S1386-6532(15)00732-5</article-id><article-id pub-id-type="doi">10.1016/j.jcv.2015.11.002</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Influenza virus emitted by naturally-infected hosts in a healthcare setting</article-title></title-group><contrib-group><contrib contrib-type="author" id="aut0005"><name><surname>Mubareka</surname><given-names>Samira</given-names></name><email>samira.mubareka@sunnybrook.ca</email><xref rid="aff0005" ref-type="aff">a</xref><xref rid="cor0005" ref-type="corresp">⁎</xref></contrib><contrib contrib-type="author" id="aut0010"><name><surname>Granados</surname><given-names>Andrea</given-names></name><email>andrea.granados@mail.utoronto.ca</email><xref rid="aff0010" ref-type="aff">b</xref></contrib><contrib contrib-type="author" id="aut0015"><name><surname>Naik</surname><given-names>Ushma</given-names></name><email>ushmanaik8@yahoo.com</email><xref rid="aff0015" ref-type="aff">c</xref></contrib><contrib contrib-type="author" id="aut0020"><name><surname>Darwish</surname><given-names>Ilyse</given-names></name><email>ilyse.darwish@utoronto.ca</email><xref rid="aff0015" ref-type="aff">c</xref></contrib><contrib contrib-type="author" id="aut0025"><name><surname>Cutts</surname><given-names>Todd A.</given-names></name><email>todd.cutts@phac-aspc.gc.ca</email><xref rid="aff0020" ref-type="aff">d</xref></contrib><contrib contrib-type="author" id="aut0030"><name><surname>Astrakianakis</surname><given-names>George</given-names></name><email>george.astrakianakis@ubc.ca</email><xref rid="aff0025" ref-type="aff">e</xref></contrib><contrib contrib-type="author" id="aut0035"><name><surname>Gubbay</surname><given-names>Jonathan B.</given-names></name><email>jonathan.gubbay@oahpp.ca</email><xref rid="aff0010" ref-type="aff">b</xref></contrib><contrib contrib-type="author" id="aut0040"><name><surname>Peci</surname><given-names>Adriana</given-names></name><email>adriana.peci@oahpp.ca</email><xref rid="aff0010" ref-type="aff">b</xref></contrib><contrib contrib-type="author" id="aut0045"><name><surname>Scott</surname><given-names>James A.</given-names></name><email>james.scott@utoronto.ca</email><xref rid="aff0030" ref-type="aff">f</xref></contrib></contrib-group><aff id="aff0005"><label>a</label>Sunnybrook Research Institute, 2075 Bayview Avenue suite B103, Toronto, ON M4N 3M1, Canada</aff><aff id="aff0010"><label>b</label>Public Health Ontario, 661 University Avenue, Suite 1701, Toronto, ON M5G 1M1, Canada</aff><aff id="aff0015"><label>c</label>Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON M4N 3M1, Canada</aff><aff id="aff0020"><label>d</label>National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, MB R3E 3R2, Canada</aff><aff id="aff0025"><label>e</label>School of Population and Public Health, University of British Columbia, Rm 366C 2206 East Mall, Vancouver, BC V6T 1Z3, Canada</aff><aff id="aff0030"><label>f</label>Division of Occupational and Environmental Health, Dalla Lana School of Public Health, University of Toronto, 223 College Street, Toronto, ON M5T 1R4, Canada</aff><author-notes><corresp id="cor0005"><label>⁎</label>Corresponding author. Sunnybrook Health Sciences Centre & Sunnybrook Research Institute, 2075 Bayview Avenue suite B103, Toronto, ON, M4N 3M1, Canada. Fax: +1 416 480 6990. <email>samira.mubareka@sunnybrook.ca</email></corresp></author-notes><pub-date pub-type="pmc-release"><day>4</day><month>11</month><year>2015</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub"><month>12</month><year>2015</year></pub-date><pub-date pub-type="epub"><day>4</day><month>11</month><year>2015</year></pub-date><volume>73</volume><fpage>105</fpage><lpage>107</lpage><history><date date-type="received"><day>12</day><month>8</month><year>2015</year></date><date date-type="rev-recd"><day>30</day><month>10</month><year>2015</year></date><date date-type="accepted"><day>1</day><month>11</month><year>2015</year></date></history><permissions><copyright-statement>Copyright © 2015 Elsevier B.V. All rights reserved.</copyright-statement><copyright-year>2015</copyright-year><copyright-holder>Elsevier B.V.</copyright-holder><license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p></license></permissions><abstract abstract-type="author-highlights" id="abs0005"><title>Highlights</title><p><list list-type="simple" id="lis0005"><list-item id="lsti0005"><label>•</label><p id="par0005">This pilot study examined the viral content of bioaerosols emitted by patients with laboratory-confirmed influenza.</p></list-item><list-item id="lsti0010"><label>•</label><p id="par0010">Nine out of fifteen patients emitted variable amounts of viral RNA.</p></list-item><list-item id="lsti0015"><label>•</label><p id="par0015">Patients with influenza may emit virus into the air which disperses >1 m and may reach the breathing zone of a healthcare worker.</p></list-item></list></p></abstract><abstract id="abs0010"><sec><title>Background</title><p>The emergence of novel respiratory viruses such as avian influenza A(H7N9) virus and the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) highlights the importance of understanding determinants of transmission to healthcare workers (HCWs) and the public.</p></sec><sec><title>Objectives</title><p>We aim to determine the viral content of the air emitted by symptomatic inpatients or long-term care residents with laboratory-confirmed influenza virus infection (emitters), and in the breathing zones of healthcare workers who attend to them.</p></sec><sec><title>Design</title><p>A prospective pilot study of patients with laboratory-confirmed influenza virus infection was undertaken. Air within 1 m of the patient was sampled using a high volume air sampler. In addition, a lower volume air sampler was placed <1 m from the patient, with another >1 m from the patient. Viral RNA was recovered from the samplers and submitted for quantitative real time PCR. In addition, personal button samplers were provided to HCWs.</p></sec><sec><title>Results</title><p>The air emitted by 15 participants with laboratory-confirmed influenza virus infection was sampled. Of the patients infected with influenza A, viral RNA was recovered from the air emitted by 9/12 patients using the low-volume sampler; no viral RNA was detected from air emitted by patients with influenza B (<italic>n</italic> = 3). Influenza virus RNA was recovered from one HCW’s sampler.</p></sec><sec><title>Conclusions</title><p>Patients with respiratory virus infection emit virus into the air which disperses to >1 m and may reach the breathing zone of a HCW. This pilot study highlights the feasibility and importance of conducting a larger-scale study to identify determinants of exposure and transmission from patient to HCW.</p></sec></abstract><kwd-group id="kwd0005"><title>Keywords</title><kwd>Influenza virus</kwd><kwd>Bioaerosol</kwd><kwd>Healthcare</kwd><kwd>Transmission</kwd><kwd>Exposure</kwd></kwd-group></article-meta></front></pmc><affiliations><list><country><li>Canada</li></country><region><li>Ontario</li></region><settlement><li>Toronto</li></settlement><orgName><li>Université de Toronto</li></orgName></list><tree><country name="Canada"><noRegion><name sortKey="Mubareka, Samira" sort="Mubareka, Samira" uniqKey="Mubareka S" first="Samira" last="Mubareka">Samira Mubareka</name></noRegion><name sortKey="Astrakianakis, George" sort="Astrakianakis, George" uniqKey="Astrakianakis G" first="George" last="Astrakianakis">George Astrakianakis</name><name sortKey="Cutts, Todd A" sort="Cutts, Todd A" uniqKey="Cutts T" first="Todd A." last="Cutts">Todd A. Cutts</name><name sortKey="Darwish, Ilyse" sort="Darwish, Ilyse" uniqKey="Darwish I" first="Ilyse" last="Darwish">Ilyse Darwish</name><name sortKey="Granados, Andrea" sort="Granados, Andrea" uniqKey="Granados A" first="Andrea" last="Granados">Andrea Granados</name><name sortKey="Gubbay, Jonathan B" sort="Gubbay, Jonathan B" uniqKey="Gubbay J" first="Jonathan B." last="Gubbay">Jonathan B. Gubbay</name><name sortKey="Naik, Ushma" sort="Naik, Ushma" uniqKey="Naik U" first="Ushma" last="Naik">Ushma Naik</name><name sortKey="Peci, Adriana" sort="Peci, Adriana" uniqKey="Peci A" first="Adriana" last="Peci">Adriana Peci</name><name sortKey="Scott, James A" sort="Scott, James A" uniqKey="Scott J" first="James A." last="Scott">James A. Scott</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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HfdSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd -nk 000E24 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= MersV1
|flux= Pmc
|étape= Checkpoint
|type= RBID
|clé= PMC:7106343
|texte= Influenza virus emitted by naturally-infected hosts in a healthcare setting
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/RBID.i -Sk "pubmed:26590688" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a MersV1
| This area was generated with Dilib version V0.6.33. |  |