From SARS to MERS: evidence and speculation
Identifieur interne : 000B59 ( Pmc/Checkpoint ); précédent : 000B58; suivant : 000B60From SARS to MERS: evidence and speculation
Auteurs : Hainv Gao [République populaire de Chine] ; Hangping Yao [République populaire de Chine] ; Shigui Yang [République populaire de Chine] ; Lanjuan Li [République populaire de Chine]Source :
- Frontiers of Medicine [ 2095-0217 ] ; 2016.
Abstract
The Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel zoonotic pathogen. In 2012, the infectious outbreak caused by MERS-CoV in Saudi Arabia has spread to more than 1600 patients in 26 countries, resulting in over 600 deaths.Without a travel history, few clinical and radiological features can reliably differentiate MERS from SARS. But in real world, comparing with SARS, MERS presents more vaguely defined epidemiology, more severe symptoms, and higher case fatality rate. In this review, we summarize the recent findings in the field of MERS-CoV, especially its molecular virology, interspecies mechanisms, clinical features, antiviral therapies, and the further investigation into this disease. As a newly emerging virus, many questions are not fully answered, including the exact mode of transmission chain, geographical distribution, and animal origins. Furthermore, a new protocol needs to be launched to rapidly evaluate the effects of unproven antiviral drugs and vaccine to fasten the clinical application of new drugs.
Url:
DOI: 10.1007/s11684-016-0466-7
PubMed: 27726088
PubMed Central: 7088694
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
PMC:7088694Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">From SARS to MERS: evidence and speculation</title>
<author><name sortKey="Gao, Hainv" sort="Gao, Hainv" uniqKey="Gao H" first="Hainv" last="Gao">Hainv Gao</name>
<affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1759 700X</institution-id>
<institution-id institution-id-type="GRID">grid.13402.34</institution-id>
<institution>State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine,</institution>
<institution>Zhejiang University,</institution>
</institution-wrap>
Hangzhou, 310003 China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Hangzhou</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1759 700X</institution-id>
<institution-id institution-id-type="GRID">grid.13402.34</institution-id>
<institution>Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases,</institution>
</institution-wrap>
Hangzhou, 310003 China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Hangzhou</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yao, Hangping" sort="Yao, Hangping" uniqKey="Yao H" first="Hangping" last="Yao">Hangping Yao</name>
<affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1759 700X</institution-id>
<institution-id institution-id-type="GRID">grid.13402.34</institution-id>
<institution>State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine,</institution>
<institution>Zhejiang University,</institution>
</institution-wrap>
Hangzhou, 310003 China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Hangzhou</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1759 700X</institution-id>
<institution-id institution-id-type="GRID">grid.13402.34</institution-id>
<institution>Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases,</institution>
</institution-wrap>
Hangzhou, 310003 China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Hangzhou</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yang, Shigui" sort="Yang, Shigui" uniqKey="Yang S" first="Shigui" last="Yang">Shigui Yang</name>
<affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1759 700X</institution-id>
<institution-id institution-id-type="GRID">grid.13402.34</institution-id>
<institution>State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine,</institution>
<institution>Zhejiang University,</institution>
</institution-wrap>
Hangzhou, 310003 China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Hangzhou</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1759 700X</institution-id>
<institution-id institution-id-type="GRID">grid.13402.34</institution-id>
<institution>Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases,</institution>
</institution-wrap>
Hangzhou, 310003 China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Hangzhou</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Li, Lanjuan" sort="Li, Lanjuan" uniqKey="Li L" first="Lanjuan" last="Li">Lanjuan Li</name>
<affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1759 700X</institution-id>
<institution-id institution-id-type="GRID">grid.13402.34</institution-id>
<institution>State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine,</institution>
<institution>Zhejiang University,</institution>
</institution-wrap>
Hangzhou, 310003 China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Hangzhou</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1759 700X</institution-id>
<institution-id institution-id-type="GRID">grid.13402.34</institution-id>
<institution>Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases,</institution>
</institution-wrap>
Hangzhou, 310003 China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Hangzhou</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">27726088</idno>
<idno type="pmc">7088694</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088694</idno>
<idno type="RBID">PMC:7088694</idno>
<idno type="doi">10.1007/s11684-016-0466-7</idno>
<date when="2016">2016</date>
<idno type="wicri:Area/Pmc/Corpus">000514</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000514</idno>
<idno type="wicri:Area/Pmc/Curation">000514</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000514</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000B59</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000B59</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">From SARS to MERS: evidence and speculation</title>
<author><name sortKey="Gao, Hainv" sort="Gao, Hainv" uniqKey="Gao H" first="Hainv" last="Gao">Hainv Gao</name>
<affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1759 700X</institution-id>
<institution-id institution-id-type="GRID">grid.13402.34</institution-id>
<institution>State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine,</institution>
<institution>Zhejiang University,</institution>
</institution-wrap>
Hangzhou, 310003 China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Hangzhou</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1759 700X</institution-id>
<institution-id institution-id-type="GRID">grid.13402.34</institution-id>
<institution>Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases,</institution>
</institution-wrap>
Hangzhou, 310003 China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Hangzhou</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yao, Hangping" sort="Yao, Hangping" uniqKey="Yao H" first="Hangping" last="Yao">Hangping Yao</name>
<affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1759 700X</institution-id>
<institution-id institution-id-type="GRID">grid.13402.34</institution-id>
<institution>State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine,</institution>
<institution>Zhejiang University,</institution>
</institution-wrap>
Hangzhou, 310003 China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Hangzhou</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1759 700X</institution-id>
<institution-id institution-id-type="GRID">grid.13402.34</institution-id>
<institution>Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases,</institution>
</institution-wrap>
Hangzhou, 310003 China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Hangzhou</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Yang, Shigui" sort="Yang, Shigui" uniqKey="Yang S" first="Shigui" last="Yang">Shigui Yang</name>
<affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1759 700X</institution-id>
<institution-id institution-id-type="GRID">grid.13402.34</institution-id>
<institution>State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine,</institution>
<institution>Zhejiang University,</institution>
</institution-wrap>
Hangzhou, 310003 China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Hangzhou</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1759 700X</institution-id>
<institution-id institution-id-type="GRID">grid.13402.34</institution-id>
<institution>Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases,</institution>
</institution-wrap>
Hangzhou, 310003 China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Hangzhou</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Li, Lanjuan" sort="Li, Lanjuan" uniqKey="Li L" first="Lanjuan" last="Li">Lanjuan Li</name>
<affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1759 700X</institution-id>
<institution-id institution-id-type="GRID">grid.13402.34</institution-id>
<institution>State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine,</institution>
<institution>Zhejiang University,</institution>
</institution-wrap>
Hangzhou, 310003 China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Hangzhou</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1759 700X</institution-id>
<institution-id institution-id-type="GRID">grid.13402.34</institution-id>
<institution>Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases,</institution>
</institution-wrap>
Hangzhou, 310003 China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Hangzhou</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Frontiers of Medicine</title>
<idno type="ISSN">2095-0217</idno>
<idno type="eISSN">2095-0225</idno>
<imprint><date when="2016">2016</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>The Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel zoonotic pathogen. In 2012, the infectious outbreak caused by MERS-CoV in Saudi Arabia has spread to more than 1600 patients in 26 countries, resulting in over 600 deaths.Without a travel history, few clinical and radiological features can reliably differentiate MERS from SARS. But in real world, comparing with SARS, MERS presents more vaguely defined epidemiology, more severe symptoms, and higher case fatality rate. In this review, we summarize the recent findings in the field of MERS-CoV, especially its molecular virology, interspecies mechanisms, clinical features, antiviral therapies, and the further investigation into this disease. As a newly emerging virus, many questions are not fully answered, including the exact mode of transmission chain, geographical distribution, and animal origins. Furthermore, a new protocol needs to be launched to rapidly evaluate the effects of unproven antiviral drugs and vaccine to fasten the clinical application of new drugs.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Zaki, Am" uniqKey="Zaki A">AM Zaki</name>
</author>
<author><name sortKey="Van Boheemen, S" uniqKey="Van Boheemen S">S van Boheemen</name>
</author>
<author><name sortKey="Bestebroer, Tm" uniqKey="Bestebroer T">TM Bestebroer</name>
</author>
<author><name sortKey="Osterhaus, Ad" uniqKey="Osterhaus A">AD Osterhaus</name>
</author>
<author><name sortKey="Fouchier, Ra" uniqKey="Fouchier R">RA Fouchier</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Zumla, A H D" uniqKey="Zumla A">A H D Zumla</name>
</author>
<author><name sortKey="Perlman, S" uniqKey="Perlman S">S Perlman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lau, Sk" uniqKey="Lau S">SK Lau</name>
</author>
<author><name sortKey="Li, Ks" uniqKey="Li K">KS Li</name>
</author>
<author><name sortKey="Tsang, Ak" uniqKey="Tsang A">AK Tsang</name>
</author>
<author><name sortKey="Lam, Cs" uniqKey="Lam C">CS Lam</name>
</author>
<author><name sortKey="Ahmed, S" uniqKey="Ahmed S">S Ahmed</name>
</author>
<author><name sortKey="Chen, H" uniqKey="Chen H">H Chen</name>
</author>
<author><name sortKey="Chan, Kh" uniqKey="Chan K">KH Chan</name>
</author>
<author><name sortKey="Woo, Pc" uniqKey="Woo P">PC Woo</name>
</author>
<author><name sortKey="Yuen, Ky" uniqKey="Yuen K">KY Yuen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Fehr, Ar" uniqKey="Fehr A">AR Fehr</name>
</author>
<author><name sortKey="Perlman, S" uniqKey="Perlman S">S Perlman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Azhar, Ei" uniqKey="Azhar E">EI Azhar</name>
</author>
<author><name sortKey="El Kafrawy, Sa" uniqKey="El Kafrawy S">SA El-Kafrawy</name>
</author>
<author><name sortKey="Farraj, Sa" uniqKey="Farraj S">SA Farraj</name>
</author>
<author><name sortKey="Hassan, Am" uniqKey="Hassan A">AM Hassan</name>
</author>
<author><name sortKey="Al Saeed, Ms" uniqKey="Al Saeed M">MS Al-Saeed</name>
</author>
<author><name sortKey="Hashem, Am" uniqKey="Hashem A">AM Hashem</name>
</author>
<author><name sortKey="Madani, Ta" uniqKey="Madani T">TA Madani</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Farag, Ea" uniqKey="Farag E">EA Farag</name>
</author>
<author><name sortKey="Reusken, Cb" uniqKey="Reusken C">CB Reusken</name>
</author>
<author><name sortKey="Haagmans, Bl" uniqKey="Haagmans B">BL Haagmans</name>
</author>
<author><name sortKey="Mohran, K S" uniqKey="Mohran K">K S Mohran</name>
</author>
<author><name sortKey="Raj, V" uniqKey="Raj V">V Raj</name>
</author>
<author><name sortKey="Pas, Sd" uniqKey="Pas S">SD Pas</name>
</author>
<author><name sortKey="Voermans, J" uniqKey="Voermans J">J Voermans</name>
</author>
<author><name sortKey="Smits, Sl" uniqKey="Smits S">SL Smits</name>
</author>
<author><name sortKey="Godeke, Gj" uniqKey="Godeke G">GJ Godeke</name>
</author>
<author><name sortKey="Al Hajri, Mm" uniqKey="Al Hajri M">MM Al-Hajri</name>
</author>
<author><name sortKey="Alhajri, Fh" uniqKey="Alhajri F">FH Alhajri</name>
</author>
<author><name sortKey="Al Romaihi, He" uniqKey="Al Romaihi H">HE Al-Romaihi</name>
</author>
<author><name sortKey="Ghobashy, H" uniqKey="Ghobashy H">H Ghobashy</name>
</author>
<author><name sortKey="El Maghraby, Mm" uniqKey="El Maghraby M">MM El-Maghraby</name>
</author>
<author><name sortKey="El Sayed, A A" uniqKey="El Sayed A">A A El-Sayed</name>
</author>
<author><name sortKey="Thani, Mh" uniqKey="Thani M">MH Thani</name>
</author>
<author><name sortKey="Al Marri, S" uniqKey="Al Marri S">S Al-Marri</name>
</author>
<author><name sortKey="Koopmans, Mp" uniqKey="Koopmans M">MP Koopmans</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chan, Sm" uniqKey="Chan S">SM Chan</name>
</author>
<author><name sortKey="Damdinjav, B" uniqKey="Damdinjav B">B Damdinjav</name>
</author>
<author><name sortKey="Perera, Ra" uniqKey="Perera R">RA Perera</name>
</author>
<author><name sortKey="Chu, Dk" uniqKey="Chu D">DK Chu</name>
</author>
<author><name sortKey="Khishgee, B" uniqKey="Khishgee B">B Khishgee</name>
</author>
<author><name sortKey="Enkhbold, B" uniqKey="Enkhbold B">B Enkhbold</name>
</author>
<author><name sortKey="Poon, Ll" uniqKey="Poon L">LL Poon</name>
</author>
<author><name sortKey="Peiris, M" uniqKey="Peiris M">M Peiris</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Briese, T" uniqKey="Briese T">T Briese</name>
</author>
<author><name sortKey="Mishra, N" uniqKey="Mishra N">N Mishra</name>
</author>
<author><name sortKey="Jain, K" uniqKey="Jain K">K Jain</name>
</author>
<author><name sortKey="Zalmout, Is" uniqKey="Zalmout I">IS Zalmout</name>
</author>
<author><name sortKey="Jabado, Oj" uniqKey="Jabado O">OJ Jabado</name>
</author>
<author><name sortKey="Karesh, Wb" uniqKey="Karesh W">WB Karesh</name>
</author>
<author><name sortKey="Daszak, P" uniqKey="Daszak P">P Daszak</name>
</author>
<author><name sortKey="Mohammed, Ob" uniqKey="Mohammed O">OB Mohammed</name>
</author>
<author><name sortKey="Alagaili, An" uniqKey="Alagaili A">AN Alagaili</name>
</author>
<author><name sortKey="Lipkin, Wi" uniqKey="Lipkin W">WI Lipkin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Haagmans, Bl" uniqKey="Haagmans B">BL Haagmans</name>
</author>
<author><name sortKey="Van Den Brand, Jm" uniqKey="Van Den Brand J">JM van den Brand</name>
</author>
<author><name sortKey="Provacia, Lb" uniqKey="Provacia L">LB Provacia</name>
</author>
<author><name sortKey="Raj, Vs" uniqKey="Raj V">VS Raj</name>
</author>
<author><name sortKey="Stittelaar, Kj" uniqKey="Stittelaar K">KJ Stittelaar</name>
</author>
<author><name sortKey="Getu, S" uniqKey="Getu S">S Getu</name>
</author>
<author><name sortKey="De Waal, L" uniqKey="De Waal L">L de Waal</name>
</author>
<author><name sortKey="Bestebroer, Tm" uniqKey="Bestebroer T">TM Bestebroer</name>
</author>
<author><name sortKey="Van Amerongen, G" uniqKey="Van Amerongen G">G van Amerongen</name>
</author>
<author><name sortKey="Verjans, Gm" uniqKey="Verjans G">GM Verjans</name>
</author>
<author><name sortKey="Fouchier, Ra" uniqKey="Fouchier R">RA Fouchier</name>
</author>
<author><name sortKey="Smits, Sl" uniqKey="Smits S">SL Smits</name>
</author>
<author><name sortKey="Kuiken, T" uniqKey="Kuiken T">T Kuiken</name>
</author>
<author><name sortKey="Osterhaus, Ad" uniqKey="Osterhaus A">AD Osterhaus</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Van Doremalen, N" uniqKey="Van Doremalen N">N van Doremalen</name>
</author>
<author><name sortKey="Miazgowicz, Kl" uniqKey="Miazgowicz K">KL Miazgowicz</name>
</author>
<author><name sortKey="Milne Price, S" uniqKey="Milne Price S">S Milne-Price</name>
</author>
<author><name sortKey="Bushmaker, T" uniqKey="Bushmaker T">T Bushmaker</name>
</author>
<author><name sortKey="Robertson, S" uniqKey="Robertson S">S Robertson</name>
</author>
<author><name sortKey="Scott, D" uniqKey="Scott D">D Scott</name>
</author>
<author><name sortKey="Kinne, J" uniqKey="Kinne J">J Kinne</name>
</author>
<author><name sortKey="Mclellan, Js" uniqKey="Mclellan J">JS McLellan</name>
</author>
<author><name sortKey="Zhu, J" uniqKey="Zhu J">J Zhu</name>
</author>
<author><name sortKey="Munster, Vj" uniqKey="Munster V">VJ Munster</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Barlan, A" uniqKey="Barlan A">A Barlan</name>
</author>
<author><name sortKey="Zhao, J" uniqKey="Zhao J">J Zhao</name>
</author>
<author><name sortKey="Sarkar, Mk" uniqKey="Sarkar M">MK Sarkar</name>
</author>
<author><name sortKey="Li, K M" uniqKey="Li K">K M Li</name>
</author>
<author><name sortKey="Cray, P J" uniqKey="Cray P">P J Cray</name>
</author>
<author><name sortKey="Perlman, S" uniqKey="Perlman S">S Perlman</name>
</author>
<author><name sortKey="Gallagher, T" uniqKey="Gallagher T">T Gallagher</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Annan, A" uniqKey="Annan A">A Annan</name>
</author>
<author><name sortKey="Baldwin, Hj" uniqKey="Baldwin H">HJ Baldwin</name>
</author>
<author><name sortKey="Corman, Vm" uniqKey="Corman V">VM Corman</name>
</author>
<author><name sortKey="Klose, Sm" uniqKey="Klose S">SM Klose</name>
</author>
<author><name sortKey="Owusu, M" uniqKey="Owusu M">M Owusu</name>
</author>
<author><name sortKey="Nkrumah, Ee" uniqKey="Nkrumah E">EE Nkrumah</name>
</author>
<author><name sortKey="Badu, Ek" uniqKey="Badu E">EK Badu</name>
</author>
<author><name sortKey="Anti, P" uniqKey="Anti P">P Anti</name>
</author>
<author><name sortKey="Agbenyega, O" uniqKey="Agbenyega O">O Agbenyega</name>
</author>
<author><name sortKey="Meyer, B" uniqKey="Meyer B">B Meyer</name>
</author>
<author><name sortKey="Oppong, S" uniqKey="Oppong S">S Oppong</name>
</author>
<author><name sortKey="Sarkodie, Ya" uniqKey="Sarkodie Y">YA Sarkodie</name>
</author>
<author><name sortKey="Kalko, Ek" uniqKey="Kalko E">EK Kalko</name>
</author>
<author><name sortKey="Lina, Ph" uniqKey="Lina P">PH Lina</name>
</author>
<author><name sortKey="Godlevska, Ev" uniqKey="Godlevska E">EV Godlevska</name>
</author>
<author><name sortKey="Reusken, C" uniqKey="Reusken C">C Reusken</name>
</author>
<author><name sortKey="Seebens, A" uniqKey="Seebens A">A Seebens</name>
</author>
<author><name sortKey="Gloza Rausch, F" uniqKey="Gloza Rausch F">F Gloza-Rausch</name>
</author>
<author><name sortKey="Vallo, P" uniqKey="Vallo P">P Vallo</name>
</author>
<author><name sortKey="Tschapka, M" uniqKey="Tschapka M">M Tschapka</name>
</author>
<author><name sortKey="Drosten, C" uniqKey="Drosten C">C Drosten</name>
</author>
<author><name sortKey="Drexler, Jf" uniqKey="Drexler J">JF Drexler</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Yang, Y" uniqKey="Yang Y">Y Yang</name>
</author>
<author><name sortKey="Du, L" uniqKey="Du L">L Du</name>
</author>
<author><name sortKey="Liu, C" uniqKey="Liu C">C Liu</name>
</author>
<author><name sortKey="Wang, L" uniqKey="Wang L">L Wang</name>
</author>
<author><name sortKey="Ma, C" uniqKey="Ma C">C Ma</name>
</author>
<author><name sortKey="Tang, J" uniqKey="Tang J">J Tang</name>
</author>
<author><name sortKey="Baric, Rs" uniqKey="Baric R">RS Baric</name>
</author>
<author><name sortKey="Jiang, S" uniqKey="Jiang S">S Jiang</name>
</author>
<author><name sortKey="Li, F" uniqKey="Li F">F Li</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Memish, Za" uniqKey="Memish Z">ZA Memish</name>
</author>
<author><name sortKey="Mishra, N" uniqKey="Mishra N">N Mishra</name>
</author>
<author><name sortKey="Olival, Kj" uniqKey="Olival K">KJ Olival</name>
</author>
<author><name sortKey="Fagbo, Sf" uniqKey="Fagbo S">SF Fagbo</name>
</author>
<author><name sortKey="Kapoor, V" uniqKey="Kapoor V">V Kapoor</name>
</author>
<author><name sortKey="Epstein, Jh" uniqKey="Epstein J">JH Epstein</name>
</author>
<author><name sortKey="Alhakeem, R" uniqKey="Alhakeem R">R Alhakeem</name>
</author>
<author><name sortKey="Durosinloun, A A" uniqKey="Durosinloun A">A A Durosinloun</name>
</author>
<author><name sortKey="Asmari, M" uniqKey="Asmari M">M Asmari</name>
</author>
<author><name sortKey="Islam, A" uniqKey="Islam A">A Islam</name>
</author>
<author><name sortKey="Kapoor, A" uniqKey="Kapoor A">A Kapoor</name>
</author>
<author><name sortKey="Briese, T" uniqKey="Briese T">T Briese</name>
</author>
<author><name sortKey="Daszak, P A" uniqKey="Daszak P">P A Daszak</name>
</author>
<author><name sortKey="Rabeeah, Aa" uniqKey="Rabeeah A">AA Rabeeah</name>
</author>
<author><name sortKey="Lipkin, Wi" uniqKey="Lipkin W">WI Lipkin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Raj, Vs" uniqKey="Raj V">VS Raj</name>
</author>
<author><name sortKey="Mou, H" uniqKey="Mou H">H Mou</name>
</author>
<author><name sortKey="Smits, Sl" uniqKey="Smits S">SL Smits</name>
</author>
<author><name sortKey="Dekkers, D M M" uniqKey="Dekkers D">D M M Dekkers</name>
</author>
<author><name sortKey="Dijkman, R" uniqKey="Dijkman R">R Dijkman</name>
</author>
<author><name sortKey="Muth, D" uniqKey="Muth D">D Muth</name>
</author>
<author><name sortKey="Demmers, Ja" uniqKey="Demmers J">JA Demmers</name>
</author>
<author><name sortKey="Zaki, A" uniqKey="Zaki A">A Zaki</name>
</author>
<author><name sortKey="Fouchier, Ra" uniqKey="Fouchier R">RA Fouchier</name>
</author>
<author><name sortKey="Thiel, V" uniqKey="Thiel V">V Thiel</name>
</author>
<author><name sortKey="Drosten, C" uniqKey="Drosten C">C Drosten</name>
</author>
<author><name sortKey="Rottier, Pj" uniqKey="Rottier P">PJ Rottier</name>
</author>
<author><name sortKey="Osterhaus, Ad" uniqKey="Osterhaus A">AD Osterhaus</name>
</author>
<author><name sortKey="Bosch, Bj" uniqKey="Bosch B">BJ Bosch</name>
</author>
<author><name sortKey="Haagmans, Bl" uniqKey="Haagmans B">BL Haagmans</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Meyerholz, Dk" uniqKey="Meyerholz D">DK Meyerholz</name>
</author>
<author><name sortKey="Lambertz, Am" uniqKey="Lambertz A">AM Lambertz</name>
</author>
<author><name sortKey="Mccray, Pb" uniqKey="Mccray P">PB McCray</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Siu, Kl" uniqKey="Siu K">KL Siu</name>
</author>
<author><name sortKey="Yeung, Ml" uniqKey="Yeung M">ML Yeung</name>
</author>
<author><name sortKey="Kok, Kh" uniqKey="Kok K">KH Kok</name>
</author>
<author><name sortKey="Yuen, Ks" uniqKey="Yuen K">KS Yuen</name>
</author>
<author><name sortKey="Kew, C" uniqKey="Kew C">C Kew</name>
</author>
<author><name sortKey="Lui, Py" uniqKey="Lui P">PY Lui</name>
</author>
<author><name sortKey="Chan, Cp" uniqKey="Chan C">CP Chan</name>
</author>
<author><name sortKey="Tse, H" uniqKey="Tse H">H Tse</name>
</author>
<author><name sortKey="Woo, Pc" uniqKey="Woo P">PC Woo</name>
</author>
<author><name sortKey="Yuen, Ky" uniqKey="Yuen K">KY Yuen</name>
</author>
<author><name sortKey="Jin, Dy" uniqKey="Jin D">DY Jin</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Josset, L" uniqKey="Josset L">L Josset</name>
</author>
<author><name sortKey="Menachery, Vd" uniqKey="Menachery V">VD Menachery</name>
</author>
<author><name sortKey="Gralinski, Le" uniqKey="Gralinski L">LE Gralinski</name>
</author>
<author><name sortKey="Agnihothram, S" uniqKey="Agnihothram S">S Agnihothram</name>
</author>
<author><name sortKey="Sova, P" uniqKey="Sova P">P Sova</name>
</author>
<author><name sortKey="Carter, Vs" uniqKey="Carter V">VS Carter</name>
</author>
<author><name sortKey="Yount, Bl" uniqKey="Yount B">BL Yount</name>
</author>
<author><name sortKey="Graham, Rl" uniqKey="Graham R">RL Graham</name>
</author>
<author><name sortKey="Baric, Rs" uniqKey="Baric R">RS Baric</name>
</author>
<author><name sortKey="Katze, Mg" uniqKey="Katze M">MG Katze</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Assiri, A" uniqKey="Assiri A">A Assiri</name>
</author>
<author><name sortKey="Al Tawfiq, Ja" uniqKey="Al Tawfiq J">JA Al-Tawfiq</name>
</author>
<author><name sortKey="Al Rabeeah, Aa" uniqKey="Al Rabeeah A">AA Al-Rabeeah</name>
</author>
<author><name sortKey="Al Rabiah, Fa" uniqKey="Al Rabiah F">FA Al-Rabiah</name>
</author>
<author><name sortKey="Al Hajjar, S" uniqKey="Al Hajjar S">S Al-Hajjar</name>
</author>
<author><name sortKey="Al Barrak, A" uniqKey="Al Barrak A">A Al-Barrak</name>
</author>
<author><name sortKey="Flemban, H" uniqKey="Flemban H">H Flemban</name>
</author>
<author><name sortKey="Al Nassir, Wn" uniqKey="Al Nassir W">WN Al-Nassir</name>
</author>
<author><name sortKey="Balkhy, H A" uniqKey="Balkhy H">H A- Balkhy</name>
</author>
<author><name sortKey="Hakeem, Rf" uniqKey="Hakeem R">RF Hakeem</name>
</author>
<author><name sortKey="Makhdoom, Hq" uniqKey="Makhdoom H">HQ Makhdoom</name>
</author>
<author><name sortKey="Zumla, Ai" uniqKey="Zumla A">AI Zumla</name>
</author>
<author><name sortKey="Memish, Za" uniqKey="Memish Z">ZA Memish</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Eckerle, I M M" uniqKey="Eckerle I">I M M Eckerle</name>
</author>
<author><name sortKey="Kallies, S" uniqKey="Kallies S">S Kallies</name>
</author>
<author><name sortKey="Gotthardt, Dn" uniqKey="Gotthardt D">DN Gotthardt</name>
</author>
<author><name sortKey="Drosten, C" uniqKey="Drosten C">C Drosten</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Saad, M" uniqKey="Saad M">M Saad</name>
</author>
<author><name sortKey="Omrani, As" uniqKey="Omrani A">AS Omrani</name>
</author>
<author><name sortKey="Baig, K" uniqKey="Baig K">K Baig</name>
</author>
<author><name sortKey="Bahloul, A" uniqKey="Bahloul A">A Bahloul</name>
</author>
<author><name sortKey="Elzein, F" uniqKey="Elzein F">F Elzein</name>
</author>
<author><name sortKey="Matin, Ma" uniqKey="Matin M">MA Matin</name>
</author>
<author><name sortKey="Selim, Ma" uniqKey="Selim M">MA Selim</name>
</author>
<author><name sortKey="Al Mutairi, M" uniqKey="Al Mutairi M">M Al Mutairi</name>
</author>
<author><name sortKey="Al Nakhli, D" uniqKey="Al Nakhli D">D Al Nakhli</name>
</author>
<author><name sortKey="Al Aidaroos, Ay" uniqKey="Al Aidaroos A">AY Al Aidaroos</name>
</author>
<author><name sortKey="Al Sherbeeni, N" uniqKey="Al Sherbeeni N">N Al Sherbeeni</name>
</author>
<author><name sortKey="Al Khashan, Hi" uniqKey="Al Khashan H">HI Al-Khashan</name>
</author>
<author><name sortKey="Memish, Za" uniqKey="Memish Z">ZA Memish</name>
</author>
<author><name sortKey="Albarrak, Am" uniqKey="Albarrak A">AM Albarrak</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Memish, Za" uniqKey="Memish Z">ZA Memish</name>
</author>
<author><name sortKey="Al Tawfiq, Ja" uniqKey="Al Tawfiq J">JA Al-Tawfiq</name>
</author>
<author><name sortKey="Makhdoom, Hq" uniqKey="Makhdoom H">HQ Makhdoom</name>
</author>
<author><name sortKey="Al Rabeeah, Aa" uniqKey="Al Rabeeah A">AA Al-Rabeeah</name>
</author>
<author><name sortKey="Assiri, A" uniqKey="Assiri A">A Assiri</name>
</author>
<author><name sortKey="Alhakeem, Rf" uniqKey="Alhakeem R">RF Alhakeem</name>
</author>
<author><name sortKey="Alrabiah, Fa" uniqKey="Alrabiah F">FA AlRabiah</name>
</author>
<author><name sortKey="Al Hajjar, S" uniqKey="Al Hajjar S">S Al Hajjar</name>
</author>
<author><name sortKey="Albarrak, A" uniqKey="Albarrak A">A Albarrak</name>
</author>
<author><name sortKey="Flemban, H" uniqKey="Flemban H">H Flemban</name>
</author>
<author><name sortKey="Balkhy, H" uniqKey="Balkhy H">H Balkhy</name>
</author>
<author><name sortKey="Barry, M" uniqKey="Barry M">M Barry</name>
</author>
<author><name sortKey="Alhassan, S" uniqKey="Alhassan S">S Alhassan</name>
</author>
<author><name sortKey="Alsubaie, S" uniqKey="Alsubaie S">S Alsubaie</name>
</author>
<author><name sortKey="Zumla, A" uniqKey="Zumla A">A Zumla</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Al Abdallat, Mm" uniqKey="Al Abdallat M">MM Al-Abdallat</name>
</author>
<author><name sortKey="Payne, Dc" uniqKey="Payne D">DC Payne</name>
</author>
<author><name sortKey="Alqasrawi, S" uniqKey="Alqasrawi S">S Alqasrawi</name>
</author>
<author><name sortKey="Rha, B" uniqKey="Rha B">B Rha</name>
</author>
<author><name sortKey="Tohme, Ra" uniqKey="Tohme R">RA Tohme</name>
</author>
<author><name sortKey="Abedi, G A" uniqKey="Abedi G">G A Abedi</name>
</author>
<author><name sortKey="Nsour, M" uniqKey="Nsour M">M Nsour</name>
</author>
<author><name sortKey="Iblan, I" uniqKey="Iblan I">I Iblan</name>
</author>
<author><name sortKey="Jarour, N" uniqKey="Jarour N">N Jarour</name>
</author>
<author><name sortKey="Farag, Nh" uniqKey="Farag N">NH Farag</name>
</author>
<author><name sortKey="Haddadin, A" uniqKey="Haddadin A">A Haddadin</name>
</author>
<author><name sortKey="Al Sanouri, T" uniqKey="Al Sanouri T">T Al-Sanouri</name>
</author>
<author><name sortKey="Tamin, A" uniqKey="Tamin A">A Tamin</name>
</author>
<author><name sortKey="Harcourt, Jl" uniqKey="Harcourt J">JL Harcourt</name>
</author>
<author><name sortKey="Kuhar, Dt" uniqKey="Kuhar D">DT Kuhar</name>
</author>
<author><name sortKey="Swerdlow, Dl" uniqKey="Swerdlow D">DL Swerdlow</name>
</author>
<author><name sortKey="Erdman, Dd" uniqKey="Erdman D">DD Erdman</name>
</author>
<author><name sortKey="Pallansch, Ma" uniqKey="Pallansch M">MA Pallansch</name>
</author>
<author><name sortKey="Haynes, Lm" uniqKey="Haynes L">LM Haynes</name>
</author>
<author><name sortKey="Gerber, Si" uniqKey="Gerber S">SI Gerber</name>
</author>
<author><name sortKey="Sabri, N" uniqKey="Sabri N">N Sabri</name>
</author>
<author><name sortKey="Al Azhari, M" uniqKey="Al Azhari M">M Al Azhari</name>
</author>
<author><name sortKey="Khazali, H" uniqKey="Khazali H">H Khazali</name>
</author>
<author><name sortKey="Al Maayah, M" uniqKey="Al Maayah M">M Al Maayah</name>
</author>
<author><name sortKey="Bilbeisi, A" uniqKey="Bilbeisi A">A Bilbeisi</name>
</author>
<author><name sortKey="Dawood, N" uniqKey="Dawood N">N Dawood</name>
</author>
<author><name sortKey="Al Zubi, B" uniqKey="Al Zubi B">B Al Zubi</name>
</author>
<author><name sortKey="Meflih, J" uniqKey="Meflih J">J Meflih</name>
</author>
<author><name sortKey="Mounds, T" uniqKey="Mounds T">T Mounds</name>
</author>
<author><name sortKey="Fitzner, J" uniqKey="Fitzner J">J Fitzner</name>
</author>
<author><name sortKey="Eltom, A" uniqKey="Eltom A">A Eltom</name>
</author>
<author><name sortKey="Mafi, A" uniqKey="Mafi A">A Mafi</name>
</author>
<author><name sortKey="Miao, C" uniqKey="Miao C">C Miao</name>
</author>
<author><name sortKey="Caidi, H" uniqKey="Caidi H">H Caidi</name>
</author>
<author><name sortKey="Trivedi, S" uniqKey="Trivedi S">S Trivedi</name>
</author>
<author><name sortKey="Kamili, S" uniqKey="Kamili S">S Kamili</name>
</author>
<author><name sortKey="Hall, Aj" uniqKey="Hall A">AJ Hall</name>
</author>
<author><name sortKey="Curns, A" uniqKey="Curns A">A Curns</name>
</author>
<author><name sortKey="Moore, J" uniqKey="Moore J">J Moore</name>
</author>
<author><name sortKey="Pham, H" uniqKey="Pham H">H Pham</name>
</author>
<author><name sortKey="Zimmerman, C" uniqKey="Zimmerman C">C Zimmerman</name>
</author>
<author><name sortKey="Farnon, E" uniqKey="Farnon E">E Farnon</name>
</author>
<author><name sortKey="Giorgi, G" uniqKey="Giorgi G">G Giorgi</name>
</author>
<author><name sortKey="Gerber, R" uniqKey="Gerber R">R Gerber</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Assiri, A" uniqKey="Assiri A">A Assiri</name>
</author>
<author><name sortKey="Mcgeer, A" uniqKey="Mcgeer A">A McGeer</name>
</author>
<author><name sortKey="Perl, Tm" uniqKey="Perl T">TM Perl</name>
</author>
<author><name sortKey="Price, C A" uniqKey="Price C">C A Price</name>
</author>
<author><name sortKey="Rabeeah, Aa" uniqKey="Rabeeah A">AA Rabeeah</name>
</author>
<author><name sortKey="Cummings, Da" uniqKey="Cummings D">DA Cummings</name>
</author>
<author><name sortKey="Alabdullatif, Zn" uniqKey="Alabdullatif Z">ZN Alabdullatif</name>
</author>
<author><name sortKey="Assad, M" uniqKey="Assad M">M Assad</name>
</author>
<author><name sortKey="Almulhim, A" uniqKey="Almulhim A">A Almulhim</name>
</author>
<author><name sortKey="Makhdoom, H" uniqKey="Makhdoom H">H Makhdoom</name>
</author>
<author><name sortKey="Madani, H" uniqKey="Madani H">H Madani</name>
</author>
<author><name sortKey="Alhakeem, R" uniqKey="Alhakeem R">R Alhakeem</name>
</author>
<author><name sortKey="Al Tawfiq, Ja" uniqKey="Al Tawfiq J">JA Al-Tawfiq</name>
</author>
<author><name sortKey="Cotten, M" uniqKey="Cotten M">M Cotten</name>
</author>
<author><name sortKey="Watson, Sj" uniqKey="Watson S">SJ Watson</name>
</author>
<author><name sortKey="Kellam, P" uniqKey="Kellam P">P Kellam</name>
</author>
<author><name sortKey="Zumla, A M Z K M C I Team" uniqKey="Zumla A">A M Z K M-C I Team Zumla</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Al Tawfiq, Ja" uniqKey="Al Tawfiq J">JA Al-Tawfiq</name>
</author>
<author><name sortKey="Hinedi, K" uniqKey="Hinedi K">K Hinedi</name>
</author>
<author><name sortKey="Ghandour, J" uniqKey="Ghandour J">J Ghandour</name>
</author>
<author><name sortKey="Khairalla, H" uniqKey="Khairalla H">H Khairalla</name>
</author>
<author><name sortKey="Musleh, S" uniqKey="Musleh S">S Musleh</name>
</author>
<author><name sortKey="Ujayli, A" uniqKey="Ujayli A">A Ujayli</name>
</author>
<author><name sortKey="Memish, Za" uniqKey="Memish Z">ZA Memish</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Arabi, Ym" uniqKey="Arabi Y">YM Arabi</name>
</author>
<author><name sortKey="Arifi, Aa" uniqKey="Arifi A">AA Arifi</name>
</author>
<author><name sortKey="Balkhy, Hh" uniqKey="Balkhy H">HH Balkhy</name>
</author>
<author><name sortKey="Najm, H" uniqKey="Najm H">H Najm</name>
</author>
<author><name sortKey="Aldawood, As" uniqKey="Aldawood A">AS Aldawood</name>
</author>
<author><name sortKey="Ghabashi, A" uniqKey="Ghabashi A">A Ghabashi</name>
</author>
<author><name sortKey="Hawa, H" uniqKey="Hawa H">H Hawa</name>
</author>
<author><name sortKey="Alothman, A" uniqKey="Alothman A">A Alothman</name>
</author>
<author><name sortKey="Khaldi, A" uniqKey="Khaldi A">A Khaldi</name>
</author>
<author><name sortKey="Al Raiy, B" uniqKey="Al Raiy B">B Al Raiy</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Thabet, F" uniqKey="Thabet F">F Thabet</name>
</author>
<author><name sortKey="Chehab, M" uniqKey="Chehab M">M Chehab</name>
</author>
<author><name sortKey="Bafaqih, H" uniqKey="Bafaqih H">H Bafaqih</name>
</author>
<author><name sortKey="Al Mohaimeed, S" uniqKey="Al Mohaimeed S">S Al Mohaimeed</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Denison, Mr" uniqKey="Denison M">MR Denison</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bin Seo, Y" uniqKey="Bin Seo Y">Y Bin Seo</name>
</author>
<author><name sortKey="Heo, Jy" uniqKey="Heo J">JY Heo</name>
</author>
<author><name sortKey="Song, Ms" uniqKey="Song M">MS Song</name>
</author>
<author><name sortKey="Lee, J" uniqKey="Lee J">J Lee</name>
</author>
<author><name sortKey="Kim, Eh" uniqKey="Kim E">EH Kim</name>
</author>
<author><name sortKey="Park, Sj" uniqKey="Park S">SJ Park</name>
</author>
<author><name sortKey="Kwon, Hi" uniqKey="Kwon H">HI Kwon</name>
</author>
<author><name sortKey="Kim, Sm" uniqKey="Kim S">SM Kim</name>
</author>
<author><name sortKey="Kim, Yi" uniqKey="Kim Y">YI Kim</name>
</author>
<author><name sortKey="Si, Yj" uniqKey="Si Y">YJ Si</name>
</author>
<author><name sortKey="Lee, Iw" uniqKey="Lee I">IW Lee</name>
</author>
<author><name sortKey="Baek, Yh" uniqKey="Baek Y">YH Baek</name>
</author>
<author><name sortKey="Choi, Ws" uniqKey="Choi W">WS Choi</name>
</author>
<author><name sortKey="Min, J" uniqKey="Min J">J Min</name>
</author>
<author><name sortKey="Jeong, Hw" uniqKey="Jeong H">HW Jeong</name>
</author>
<author><name sortKey="Choi, Yk" uniqKey="Choi Y">YK Choi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hui, Ds" uniqKey="Hui D">DS Hui</name>
</author>
<author><name sortKey="Memish, Za" uniqKey="Memish Z">ZA Memish</name>
</author>
<author><name sortKey="Zumla, A" uniqKey="Zumla A">A Zumla</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="De Wilde, Ah" uniqKey="De Wilde A">AH de Wilde</name>
</author>
<author><name sortKey="Raj, Vs" uniqKey="Raj V">VS Raj</name>
</author>
<author><name sortKey="Oudshoorn, D" uniqKey="Oudshoorn D">D Oudshoorn</name>
</author>
<author><name sortKey="Bestebroer, Tm" uniqKey="Bestebroer T">TM Bestebroer</name>
</author>
<author><name sortKey="Van Nieuwkoop, S" uniqKey="Van Nieuwkoop S">S van Nieuwkoop</name>
</author>
<author><name sortKey="Limpens, Rw" uniqKey="Limpens R">RW Limpens</name>
</author>
<author><name sortKey="Posthuma, Cc" uniqKey="Posthuma C">CC Posthuma</name>
</author>
<author><name sortKey="Van Der Meer, Y" uniqKey="Van Der Meer Y">Y van der Meer</name>
</author>
<author><name sortKey="Barcena, M" uniqKey="Barcena M">M Bárcena</name>
</author>
<author><name sortKey="Haagmans, Bl" uniqKey="Haagmans B">BL Haagmans</name>
</author>
<author><name sortKey="Snijder, Ej" uniqKey="Snijder E">EJ Snijder</name>
</author>
<author><name sortKey="Van Den Hoogen, Bg" uniqKey="Van Den Hoogen B">BG van den Hoogen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Falzarano, D" uniqKey="Falzarano D">D Falzarano</name>
</author>
<author><name sortKey="De Wit, E" uniqKey="De Wit E">E de Wit</name>
</author>
<author><name sortKey="Martellaro, C" uniqKey="Martellaro C">C Martellaro</name>
</author>
<author><name sortKey="Callison, J" uniqKey="Callison J">J Callison</name>
</author>
<author><name sortKey="Munster, Vj" uniqKey="Munster V">VJ Munster</name>
</author>
<author><name sortKey="Feldmann, H" uniqKey="Feldmann H">H Feldmann</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Omrani, As" uniqKey="Omrani A">AS Omrani</name>
</author>
<author><name sortKey="Saad, Mm" uniqKey="Saad M">MM Saad</name>
</author>
<author><name sortKey="Baig, K" uniqKey="Baig K">K Baig</name>
</author>
<author><name sortKey="Bahloul, A" uniqKey="Bahloul A">A Bahloul</name>
</author>
<author><name sortKey="Abdul Matin, M" uniqKey="Abdul Matin M">M Abdul-Matin</name>
</author>
<author><name sortKey="Alaidaroos, Ay" uniqKey="Alaidaroos A">AY Alaidaroos</name>
</author>
<author><name sortKey="Almakhlafi, Ga" uniqKey="Almakhlafi G">GA Almakhlafi</name>
</author>
<author><name sortKey="Albarrak, Mm" uniqKey="Albarrak M">MM Albarrak</name>
</author>
<author><name sortKey="Memish, Za" uniqKey="Memish Z">ZA Memish</name>
</author>
<author><name sortKey="Albarrak, Am" uniqKey="Albarrak A">AM Albarrak</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chan, Jf" uniqKey="Chan J">JF Chan</name>
</author>
<author><name sortKey="Chan, Kh" uniqKey="Chan K">KH Chan</name>
</author>
<author><name sortKey="Kao, Ry" uniqKey="Kao R">RY Kao</name>
</author>
<author><name sortKey="To, Kk" uniqKey="To K">KK To</name>
</author>
<author><name sortKey="Zheng, Bj" uniqKey="Zheng B">BJ Zheng</name>
</author>
<author><name sortKey="Li, Cp" uniqKey="Li C">CP Li</name>
</author>
<author><name sortKey="Li, Pt" uniqKey="Li P">PT Li</name>
</author>
<author><name sortKey="Dai, J" uniqKey="Dai J">J Dai</name>
</author>
<author><name sortKey="Mok, Fk" uniqKey="Mok F">FK Mok</name>
</author>
<author><name sortKey="Chen, H" uniqKey="Chen H">H Chen</name>
</author>
<author><name sortKey="Hayden, Fg" uniqKey="Hayden F">FG Hayden</name>
</author>
<author><name sortKey="Yuen, Ky" uniqKey="Yuen K">KY Yuen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sui, J" uniqKey="Sui J">J Sui</name>
</author>
<author><name sortKey="Li, W" uniqKey="Li W">W Li</name>
</author>
<author><name sortKey="Murakami, A" uniqKey="Murakami A">A Murakami</name>
</author>
<author><name sortKey="Tamin, A M L" uniqKey="Tamin A">A M L Tamin</name>
</author>
<author><name sortKey="Wong, Sk" uniqKey="Wong S">SK Wong</name>
</author>
<author><name sortKey="Moore, Mj" uniqKey="Moore M">MJ Moore</name>
</author>
<author><name sortKey="Tallarico, As" uniqKey="Tallarico A">AS Tallarico</name>
</author>
<author><name sortKey="Olurinde, M" uniqKey="Olurinde M">M Olurinde</name>
</author>
<author><name sortKey="Choe, H" uniqKey="Choe H">H Choe</name>
</author>
<author><name sortKey="Anderson, Lj" uniqKey="Anderson L">LJ Anderson</name>
</author>
<author><name sortKey="Bellini, Wj" uniqKey="Bellini W">WJ Bellini</name>
</author>
<author><name sortKey="Farzan, M" uniqKey="Farzan M">M Farzan</name>
</author>
<author><name sortKey="Marasco, Wa" uniqKey="Marasco W">WA Marasco</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ter Meulen, J" uniqKey="Ter Meulen J">J ter Meulen</name>
</author>
<author><name sortKey="Bakker, Ab" uniqKey="Bakker A">AB Bakker</name>
</author>
<author><name sortKey="Van Den Brink, En" uniqKey="Van Den Brink E">EN van den Brink</name>
</author>
<author><name sortKey="Weverling, Gj" uniqKey="Weverling G">GJ Weverling</name>
</author>
<author><name sortKey="Martina, Be" uniqKey="Martina B">BE Martina</name>
</author>
<author><name sortKey="Haagmans, Bl" uniqKey="Haagmans B">BL Haagmans</name>
</author>
<author><name sortKey="Kuiken, T" uniqKey="Kuiken T">T Kuiken</name>
</author>
<author><name sortKey="De Kruif, J" uniqKey="De Kruif J">J de Kruif</name>
</author>
<author><name sortKey="Preiser, W" uniqKey="Preiser W">W Preiser</name>
</author>
<author><name sortKey="Spaan, W" uniqKey="Spaan W">W Spaan</name>
</author>
<author><name sortKey="Gelderblom, Hr" uniqKey="Gelderblom H">HR Gelderblom</name>
</author>
<author><name sortKey="Goudsmit, J" uniqKey="Goudsmit J">J Goudsmit</name>
</author>
<author><name sortKey="Osterhaus, Ad" uniqKey="Osterhaus A">AD Osterhaus</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Traggiai, E" uniqKey="Traggiai E">E Traggiai</name>
</author>
<author><name sortKey="Becker, S" uniqKey="Becker S">S Becker</name>
</author>
<author><name sortKey="Subbarao, K" uniqKey="Subbarao K">K Subbarao</name>
</author>
<author><name sortKey="Kolesnikova, L" uniqKey="Kolesnikova L">L Kolesnikova</name>
</author>
<author><name sortKey="Uematsu, Y" uniqKey="Uematsu Y">Y Uematsu</name>
</author>
<author><name sortKey="Gismondo, Mr" uniqKey="Gismondo M">MR Gismondo</name>
</author>
<author><name sortKey="Murphy, Br" uniqKey="Murphy B">BR Murphy</name>
</author>
<author><name sortKey="Rappuoli, R" uniqKey="Rappuoli R">R Rappuoli</name>
</author>
<author><name sortKey="Lanzavecchia, A" uniqKey="Lanzavecchia A">A Lanzavecchia</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Du, L" uniqKey="Du L">L Du</name>
</author>
<author><name sortKey="Zhao, G" uniqKey="Zhao G">G Zhao</name>
</author>
<author><name sortKey="Yang, Y" uniqKey="Yang Y">Y Yang</name>
</author>
<author><name sortKey="Qiu, H" uniqKey="Qiu H">H Qiu</name>
</author>
<author><name sortKey="Wang, L" uniqKey="Wang L">L Wang</name>
</author>
<author><name sortKey="Kou, Z" uniqKey="Kou Z">Z Kou</name>
</author>
<author><name sortKey="Tao, X" uniqKey="Tao X">X Tao</name>
</author>
<author><name sortKey="Yu, H" uniqKey="Yu H">H Yu</name>
</author>
<author><name sortKey="Sun, S" uniqKey="Sun S">S Sun</name>
</author>
<author><name sortKey="Tseng, Ct" uniqKey="Tseng C">CT Tseng</name>
</author>
<author><name sortKey="Jiang, S" uniqKey="Jiang S">S Jiang</name>
</author>
<author><name sortKey="Li, F" uniqKey="Li F">F Li</name>
</author>
<author><name sortKey="Zhou, Y" uniqKey="Zhou Y">Y Zhou</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ying, T" uniqKey="Ying T">T Ying</name>
</author>
<author><name sortKey="Du, L" uniqKey="Du L">L Du</name>
</author>
<author><name sortKey="Ju, Tw" uniqKey="Ju T">TW Ju</name>
</author>
<author><name sortKey="Prabakaran, P" uniqKey="Prabakaran P">P Prabakaran</name>
</author>
<author><name sortKey="Lau, Cc" uniqKey="Lau C">CC Lau</name>
</author>
<author><name sortKey="Lu, L" uniqKey="Lu L">L Lu</name>
</author>
<author><name sortKey="Liu, Q" uniqKey="Liu Q">Q Liu</name>
</author>
<author><name sortKey="Wang, L" uniqKey="Wang L">L Wang</name>
</author>
<author><name sortKey="Feng, Y" uniqKey="Feng Y">Y Feng</name>
</author>
<author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name>
</author>
<author><name sortKey="Zheng, Bj" uniqKey="Zheng B">BJ Zheng</name>
</author>
<author><name sortKey="Yuen, Ky" uniqKey="Yuen K">KY Yuen</name>
</author>
<author><name sortKey="Jiang, S" uniqKey="Jiang S">S Jiang</name>
</author>
<author><name sortKey="Dimitrov, Ds" uniqKey="Dimitrov D">DS Dimitrov</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jiang, L" uniqKey="Jiang L">L Jiang</name>
</author>
<author><name sortKey="Wang, N" uniqKey="Wang N">N Wang</name>
</author>
<author><name sortKey="Zuo, T" uniqKey="Zuo T">T Zuo</name>
</author>
<author><name sortKey="Shi, X" uniqKey="Shi X">X Shi</name>
</author>
<author><name sortKey="Poon, Km" uniqKey="Poon K">KM Poon</name>
</author>
<author><name sortKey="Wu, Y" uniqKey="Wu Y">Y Wu</name>
</author>
<author><name sortKey="Gao, F" uniqKey="Gao F">F Gao</name>
</author>
<author><name sortKey="Li, D" uniqKey="Li D">D Li</name>
</author>
<author><name sortKey="Wang, R" uniqKey="Wang R">R Wang</name>
</author>
<author><name sortKey="Guo, J" uniqKey="Guo J">J Guo</name>
</author>
<author><name sortKey="Fu, L" uniqKey="Fu L">L Fu</name>
</author>
<author><name sortKey="Yuen, Ky" uniqKey="Yuen K">KY Yuen</name>
</author>
<author><name sortKey="Zheng, Bj" uniqKey="Zheng B">BJ Zheng</name>
</author>
<author><name sortKey="Wang, X" uniqKey="Wang X">X Wang</name>
</author>
<author><name sortKey="Zhang, L" uniqKey="Zhang L">L Zhang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tang, Xc" uniqKey="Tang X">XC Tang</name>
</author>
<author><name sortKey="Agnihothram, Ss" uniqKey="Agnihothram S">SS Agnihothram</name>
</author>
<author><name sortKey="Jiao, Y" uniqKey="Jiao Y">Y Jiao</name>
</author>
<author><name sortKey="Stanhope, J" uniqKey="Stanhope J">J Stanhope</name>
</author>
<author><name sortKey="Graham, Rl" uniqKey="Graham R">RL Graham</name>
</author>
<author><name sortKey="Peterson, Ec" uniqKey="Peterson E">EC Peterson</name>
</author>
<author><name sortKey="Avnir, Y" uniqKey="Avnir Y">Y Avnir</name>
</author>
<author><name sortKey="Tallarico, As" uniqKey="Tallarico A">AS Tallarico</name>
</author>
<author><name sortKey="Sheehan, J" uniqKey="Sheehan J">J Sheehan</name>
</author>
<author><name sortKey="Zhu, Q" uniqKey="Zhu Q">Q Zhu</name>
</author>
<author><name sortKey="Baric, Rs" uniqKey="Baric R">RS Baric</name>
</author>
<author><name sortKey="Marasco, Wa" uniqKey="Marasco W">WA Marasco</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ying, T" uniqKey="Ying T">T Ying</name>
</author>
<author><name sortKey="Li, H" uniqKey="Li H">H Li</name>
</author>
<author><name sortKey="Lu, L" uniqKey="Lu L">L Lu</name>
</author>
<author><name sortKey="Dimitrov, Ds" uniqKey="Dimitrov D">DS Dimitrov</name>
</author>
<author><name sortKey="Jiang, S" uniqKey="Jiang S">S Jiang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lu, L" uniqKey="Lu L">L Lu</name>
</author>
<author><name sortKey="Liu, Q" uniqKey="Liu Q">Q Liu</name>
</author>
<author><name sortKey="Zhu, Y" uniqKey="Zhu Y">Y Zhu</name>
</author>
<author><name sortKey="Chan, Kh" uniqKey="Chan K">KH Chan</name>
</author>
<author><name sortKey="Qin, L" uniqKey="Qin L">L Qin</name>
</author>
<author><name sortKey="Li, Y" uniqKey="Li Y">Y Li</name>
</author>
<author><name sortKey="Wang, Q" uniqKey="Wang Q">Q Wang</name>
</author>
<author><name sortKey="Chan, Jf" uniqKey="Chan J">JF Chan</name>
</author>
<author><name sortKey="Du, L" uniqKey="Du L">L Du</name>
</author>
<author><name sortKey="Yu, F" uniqKey="Yu F">F Yu</name>
</author>
<author><name sortKey="Ma, C" uniqKey="Ma C">C Ma</name>
</author>
<author><name sortKey="Ye, S" uniqKey="Ye S">S Ye</name>
</author>
<author><name sortKey="Yuen, Ky" uniqKey="Yuen K">KY Yuen</name>
</author>
<author><name sortKey="Zhang, R" uniqKey="Zhang R">R Zhang</name>
</author>
<author><name sortKey="Jiang, S" uniqKey="Jiang S">S Jiang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Borio, L" uniqKey="Borio L">L Borio</name>
</author>
<author><name sortKey="Cox, E" uniqKey="Cox E">E Cox</name>
</author>
<author><name sortKey="Lurie, N" uniqKey="Lurie N">N Lurie</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Haagmans, Bl" uniqKey="Haagmans B">BL Haagmans</name>
</author>
<author><name sortKey="Van Den Brand, Jm" uniqKey="Van Den Brand J">JM van den Brand</name>
</author>
<author><name sortKey="Raj, Vs" uniqKey="Raj V">VS Raj</name>
</author>
<author><name sortKey="Volz, A" uniqKey="Volz A">A Volz</name>
</author>
<author><name sortKey="Wohlsein, P" uniqKey="Wohlsein P">P Wohlsein</name>
</author>
<author><name sortKey="Smits, Sl" uniqKey="Smits S">SL Smits</name>
</author>
<author><name sortKey="Schipper, D" uniqKey="Schipper D">D Schipper</name>
</author>
<author><name sortKey="Bestebroer, Tm" uniqKey="Bestebroer T">TM Bestebroer</name>
</author>
<author><name sortKey="Okba, N" uniqKey="Okba N">N Okba</name>
</author>
<author><name sortKey="Fux, R" uniqKey="Fux R">R Fux</name>
</author>
<author><name sortKey="Bensaid, A" uniqKey="Bensaid A">A Bensaid</name>
</author>
<author><name sortKey="Solanes Foz, D" uniqKey="Solanes Foz D">D Solanes Foz</name>
</author>
<author><name sortKey="Kuiken, T" uniqKey="Kuiken T">T Kuiken</name>
</author>
<author><name sortKey="Baumg Rtner, W" uniqKey="Baumg Rtner W">W Baumgärtner</name>
</author>
<author><name sortKey="Segales, J" uniqKey="Segales J">J Segalés</name>
</author>
<author><name sortKey="Sutter, G" uniqKey="Sutter G">G Sutter</name>
</author>
<author><name sortKey="Osterhaus, Ad" uniqKey="Osterhaus A">AD Osterhaus</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<pmc article-type="review-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Front Med</journal-id>
<journal-id journal-id-type="iso-abbrev">Front Med</journal-id>
<journal-title-group><journal-title>Frontiers of Medicine</journal-title>
</journal-title-group>
<issn pub-type="ppub">2095-0217</issn>
<issn pub-type="epub">2095-0225</issn>
<publisher><publisher-name>Higher Education Press</publisher-name>
<publisher-loc>Beijing</publisher-loc>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">27726088</article-id>
<article-id pub-id-type="pmc">7088694</article-id>
<article-id pub-id-type="publisher-id">466</article-id>
<article-id pub-id-type="doi">10.1007/s11684-016-0466-7</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Review</subject>
</subj-group>
</article-categories>
<title-group><article-title>From SARS to MERS: evidence and speculation</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Gao</surname>
<given-names>Hainv</given-names>
</name>
<xref ref-type="aff" rid="Aff1">1</xref>
<xref ref-type="aff" rid="Aff2">2</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Yao</surname>
<given-names>Hangping</given-names>
</name>
<xref ref-type="aff" rid="Aff1">1</xref>
<xref ref-type="aff" rid="Aff2">2</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Yang</surname>
<given-names>Shigui</given-names>
</name>
<xref ref-type="aff" rid="Aff1">1</xref>
<xref ref-type="aff" rid="Aff2">2</xref>
</contrib>
<contrib contrib-type="author" corresp="yes"><name><surname>Li</surname>
<given-names>Lanjuan</given-names>
</name>
<address><email>ljli@zju.edu.cn</email>
</address>
<xref ref-type="aff" rid="Aff1">1</xref>
<xref ref-type="aff" rid="Aff2">2</xref>
</contrib>
<aff id="Aff1"><label>1</label>
<institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1759 700X</institution-id>
<institution-id institution-id-type="GRID">grid.13402.34</institution-id>
<institution>State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine,</institution>
<institution>Zhejiang University,</institution>
</institution-wrap>
Hangzhou, 310003 China</aff>
<aff id="Aff2"><label>2</label>
<institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1759 700X</institution-id>
<institution-id institution-id-type="GRID">grid.13402.34</institution-id>
<institution>Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases,</institution>
</institution-wrap>
Hangzhou, 310003 China</aff>
</contrib-group>
<pub-date pub-type="epub"><day>23</day>
<month>12</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="ppub"><year>2016</year>
</pub-date>
<volume>10</volume>
<issue>4</issue>
<fpage>377</fpage>
<lpage>382</lpage>
<history><date date-type="received"><day>9</day>
<month>8</month>
<year>2015</year>
</date>
<date date-type="accepted"><day>12</day>
<month>6</month>
<year>2016</year>
</date>
</history>
<permissions><copyright-statement>© Higher Education Press and Springer-Verlag Berlin Heidelberg 2016</copyright-statement>
<license><license-p>This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.</license-p>
</license>
</permissions>
<abstract id="Abs1"><p>The Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel zoonotic pathogen. In 2012, the infectious outbreak caused by MERS-CoV in Saudi Arabia has spread to more than 1600 patients in 26 countries, resulting in over 600 deaths.Without a travel history, few clinical and radiological features can reliably differentiate MERS from SARS. But in real world, comparing with SARS, MERS presents more vaguely defined epidemiology, more severe symptoms, and higher case fatality rate. In this review, we summarize the recent findings in the field of MERS-CoV, especially its molecular virology, interspecies mechanisms, clinical features, antiviral therapies, and the further investigation into this disease. As a newly emerging virus, many questions are not fully answered, including the exact mode of transmission chain, geographical distribution, and animal origins. Furthermore, a new protocol needs to be launched to rapidly evaluate the effects of unproven antiviral drugs and vaccine to fasten the clinical application of new drugs.</p>
</abstract>
<kwd-group xml:lang="en"><title>Keywords</title>
<kwd>middle east respiratory syndrome</kwd>
<kwd>animal origin</kwd>
<kwd>cross-species transmission</kwd>
<kwd>monoclonal antibody</kwd>
</kwd-group>
<custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name>
<meta-value>© Higher Education Press and Springer-Verlag Berlin Heidelberg 2016</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
</front>
</pmc>
<affiliations><list><country><li>République populaire de Chine</li>
</country>
</list>
<tree><country name="République populaire de Chine"><noRegion><name sortKey="Gao, Hainv" sort="Gao, Hainv" uniqKey="Gao H" first="Hainv" last="Gao">Hainv Gao</name>
</noRegion>
<name sortKey="Gao, Hainv" sort="Gao, Hainv" uniqKey="Gao H" first="Hainv" last="Gao">Hainv Gao</name>
<name sortKey="Li, Lanjuan" sort="Li, Lanjuan" uniqKey="Li L" first="Lanjuan" last="Li">Lanjuan Li</name>
<name sortKey="Li, Lanjuan" sort="Li, Lanjuan" uniqKey="Li L" first="Lanjuan" last="Li">Lanjuan Li</name>
<name sortKey="Yang, Shigui" sort="Yang, Shigui" uniqKey="Yang S" first="Shigui" last="Yang">Shigui Yang</name>
<name sortKey="Yang, Shigui" sort="Yang, Shigui" uniqKey="Yang S" first="Shigui" last="Yang">Shigui Yang</name>
<name sortKey="Yao, Hangping" sort="Yao, Hangping" uniqKey="Yao H" first="Hangping" last="Yao">Hangping Yao</name>
<name sortKey="Yao, Hangping" sort="Yao, Hangping" uniqKey="Yao H" first="Hangping" last="Yao">Hangping Yao</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Pmc/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000B59 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd -nk 000B59 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= MersV1 |flux= Pmc |étape= Checkpoint |type= RBID |clé= PMC:7088694 |texte= From SARS to MERS: evidence and speculation }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/RBID.i -Sk "pubmed:27726088" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd \ | NlmPubMed2Wicri -a MersV1
![]() | This area was generated with Dilib version V0.6.33. | ![]() |