Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection
Identifieur interne : 001F22 ( Ncbi/Merge ); précédent : 001F21; suivant : 001F23Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection
Auteurs : V. Stalin Raj [Pays-Bas] ; Nisreen M. A. Okba [Pays-Bas] ; Javier Gutierrez-Alvarez [Espagne] ; Dubravka Drabek [Pays-Bas] ; Brenda Van Dieren [Pays-Bas] ; W. Widagdo [Pays-Bas] ; Mart M. Lamers [Pays-Bas] ; Ivy Widjaja [Pays-Bas] ; Raul Fernandez-Delgado [Espagne] ; Isabel Sola [Espagne] ; Albert Bensaid [Espagne] ; Marion P. Koopmans [Pays-Bas] ; Joaquim Segalés [Espagne] ; Albert D. M. E. Osterhaus [Pays-Bas, Allemagne] ; Berend Jan Bosch [Pays-Bas] ; Luis Enjuanes [Espagne] ; Bart L. Haagmans [Pays-Bas]Source :
- Science Advances [ 2375-2548 ] ; 2018.
Descripteurs français
- KwdFr :
- Animaux, Anticorps antiviraux (administration et posologie), Anticorps antiviraux (biosynthèse), Anticorps antiviraux (immunologie), Anticorps neutralisants (administration et posologie), Anticorps neutralisants (biosynthèse), Anticorps neutralisants (immunologie), Anticorps à domaine unique, Chameaux, Coronavirus du syndrome respiratoire du Moyen-Orient (immunologie), Femelle, Humains, Infections à coronavirus (), Infections à coronavirus (immunologie), Infections à coronavirus (virologie), Liaison aux protéines, Mâle, Pénétration virale (), Souris, Tests de neutralisation.
- MESH :
- administration et posologie : Anticorps antiviraux, Anticorps neutralisants.
- biosynthèse : Anticorps antiviraux, Anticorps neutralisants.
- immunologie : Anticorps antiviraux, Anticorps neutralisants, Coronavirus du syndrome respiratoire du Moyen-Orient, Infections à coronavirus.
- virologie : Infections à coronavirus.
- Animaux, Anticorps à domaine unique, Chameaux, Femelle, Humains, Infections à coronavirus, Liaison aux protéines, Mâle, Pénétration virale, Souris, Tests de neutralisation.
English descriptors
- KwdEn :
- Animals, Antibodies, Neutralizing (administration & dosage), Antibodies, Neutralizing (biosynthesis), Antibodies, Neutralizing (immunology), Antibodies, Viral (administration & dosage), Antibodies, Viral (biosynthesis), Antibodies, Viral (immunology), Camelus, Coronavirus Infections (immunology), Coronavirus Infections (prevention & control), Coronavirus Infections (virology), Female, Humans, Male, Mice, Middle East Respiratory Syndrome Coronavirus (immunology), Neutralization Tests, Protein Binding, Single-Domain Antibodies, Virus Internalization (drug effects).
- MESH :
- chemical , administration & dosage : Antibodies, Neutralizing, Antibodies, Viral.
- chemical , biosynthesis : Antibodies, Neutralizing, Antibodies, Viral.
- chemical , immunology : Antibodies, Neutralizing, Antibodies, Viral.
- drug effects : Virus Internalization.
- immunology : Coronavirus Infections, Middle East Respiratory Syndrome Coronavirus.
- prevention & control : Coronavirus Infections.
- virology : Coronavirus Infections.
- Animals, Camelus, Female, Humans, Male, Mice, Neutralization Tests, Protein Binding, Single-Domain Antibodies.
Abstract
Dromedary camel heavy chain–only antibodies may provide novel intervention strategies against MERS coronavirus.
Url:
DOI: 10.1126/sciadv.aas9667
PubMed: 30101189
PubMed Central: 6082650
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 001141
- to stream Pmc, to step Curation: 001141
- to stream Pmc, to step Checkpoint: 000625
- to stream PubMed, to step Corpus: 000818
- to stream PubMed, to step Curation: 000818
- to stream PubMed, to step Checkpoint: 000991
Links to Exploration step
PMC:6082650Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection</title><author><name sortKey="Stalin Raj, V" sort="Stalin Raj, V" uniqKey="Stalin Raj V" first="V." last="Stalin Raj">V. Stalin Raj</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Okba, Nisreen M A" sort="Okba, Nisreen M A" uniqKey="Okba N" first="Nisreen M. A." last="Okba">Nisreen M. A. Okba</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Gutierrez Alvarez, Javier" sort="Gutierrez Alvarez, Javier" uniqKey="Gutierrez Alvarez J" first="Javier" last="Gutierrez-Alvarez">Javier Gutierrez-Alvarez</name><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Drabek, Dubravka" sort="Drabek, Dubravka" uniqKey="Drabek D" first="Dubravka" last="Drabek">Dubravka Drabek</name><affiliation wicri:level="3"><nlm:aff id="aff3">Department of Cell Biology, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Cell Biology, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Van Dieren, Brenda" sort="Van Dieren, Brenda" uniqKey="Van Dieren B" first="Brenda" last="Van Dieren">Brenda Van Dieren</name><affiliation wicri:level="4"><nlm:aff id="aff4">Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName><orgName type="university">Université d'Utrecht</orgName></affiliation></author><author><name sortKey="Widagdo, W" sort="Widagdo, W" uniqKey="Widagdo W" first="W." last="Widagdo">W. Widagdo</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Lamers, Mart M" sort="Lamers, Mart M" uniqKey="Lamers M" first="Mart M." last="Lamers">Mart M. Lamers</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Widjaja, Ivy" sort="Widjaja, Ivy" uniqKey="Widjaja I" first="Ivy" last="Widjaja">Ivy Widjaja</name><affiliation wicri:level="4"><nlm:aff id="aff4">Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName><orgName type="university">Université d'Utrecht</orgName></affiliation></author><author><name sortKey="Fernandez Delgado, Raul" sort="Fernandez Delgado, Raul" uniqKey="Fernandez Delgado R" first="Raul" last="Fernandez-Delgado">Raul Fernandez-Delgado</name><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Sola, Isabel" sort="Sola, Isabel" uniqKey="Sola I" first="Isabel" last="Sola">Isabel Sola</name><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Bensaid, Albert" sort="Bensaid, Albert" uniqKey="Bensaid A" first="Albert" last="Bensaid">Albert Bensaid</name><affiliation wicri:level="2"><nlm:aff id="aff5">Institut de Recerca i Tecnologia Agroalimentàries (IRTA), Centre de Recerca en Sanitat Animal [CReSA, IRTA–Universitat Autònoma de Barcelona (UAB)], Campus de la UAB, 08193 Bellaterra, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Institut de Recerca i Tecnologia Agroalimentàries (IRTA), Centre de Recerca en Sanitat Animal [CReSA, IRTA–Universitat Autònoma de Barcelona (UAB)], Campus de la UAB, 08193 Bellaterra</wicri:regionArea><placeName><region nuts="2" type="communauté">Catalogne</region></placeName></affiliation></author><author><name sortKey="Koopmans, Marion P" sort="Koopmans, Marion P" uniqKey="Koopmans M" first="Marion P." last="Koopmans">Marion P. Koopmans</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Segales, Joaquim" sort="Segales, Joaquim" uniqKey="Segales J" first="Joaquim" last="Segalés">Joaquim Segalés</name><affiliation wicri:level="2"><nlm:aff id="aff6">UAB, CReSA (IRTA-UAB), Campus de la UAB, 08193 Bellaterra, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>UAB, CReSA (IRTA-UAB), Campus de la UAB, 08193 Bellaterra</wicri:regionArea><placeName><region nuts="2" type="communauté">Catalogne</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff7">Departament de Sanitat i Anatomia Animals, Facultat de Veterinària, UAB, 08193 Bellaterra, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Departament de Sanitat i Anatomia Animals, Facultat de Veterinària, UAB, 08193 Bellaterra</wicri:regionArea><placeName><region nuts="2" type="communauté">Catalogne</region></placeName></affiliation></author><author><name sortKey="Osterhaus, Albert D M E" sort="Osterhaus, Albert D M E" uniqKey="Osterhaus A" first="Albert D. M. E." last="Osterhaus">Albert D. M. E. Osterhaus</name><affiliation wicri:level="3"><nlm:aff id="aff8">Artemis One Health, Utrecht, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Artemis One Health, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff9">Center for Infection Medicine and Zoonoses Research, University of Veterinary Medicine, Hannover, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Center for Infection Medicine and Zoonoses Research, University of Veterinary Medicine, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Bosch, Berend Jan" sort="Bosch, Berend Jan" uniqKey="Bosch B" first="Berend Jan" last="Bosch">Berend Jan Bosch</name><affiliation wicri:level="4"><nlm:aff id="aff4">Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName><orgName type="university">Université d'Utrecht</orgName></affiliation></author><author><name sortKey="Enjuanes, Luis" sort="Enjuanes, Luis" uniqKey="Enjuanes L" first="Luis" last="Enjuanes">Luis Enjuanes</name><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Haagmans, Bart L" sort="Haagmans, Bart L" uniqKey="Haagmans B" first="Bart L." last="Haagmans">Bart L. Haagmans</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">30101189</idno><idno type="pmc">6082650</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082650</idno><idno type="RBID">PMC:6082650</idno><idno type="doi">10.1126/sciadv.aas9667</idno><date when="2018">2018</date><idno type="wicri:Area/Pmc/Corpus">001141</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001141</idno><idno type="wicri:Area/Pmc/Curation">001141</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001141</idno><idno type="wicri:Area/Pmc/Checkpoint">000625</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000625</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:30101189</idno><idno type="wicri:Area/PubMed/Corpus">000818</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000818</idno><idno type="wicri:Area/PubMed/Curation">000818</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000818</idno><idno type="wicri:Area/PubMed/Checkpoint">000991</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000991</idno><idno type="wicri:Area/Ncbi/Merge">001F22</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection</title><author><name sortKey="Stalin Raj, V" sort="Stalin Raj, V" uniqKey="Stalin Raj V" first="V." last="Stalin Raj">V. Stalin Raj</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Okba, Nisreen M A" sort="Okba, Nisreen M A" uniqKey="Okba N" first="Nisreen M. A." last="Okba">Nisreen M. A. Okba</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Gutierrez Alvarez, Javier" sort="Gutierrez Alvarez, Javier" uniqKey="Gutierrez Alvarez J" first="Javier" last="Gutierrez-Alvarez">Javier Gutierrez-Alvarez</name><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Drabek, Dubravka" sort="Drabek, Dubravka" uniqKey="Drabek D" first="Dubravka" last="Drabek">Dubravka Drabek</name><affiliation wicri:level="3"><nlm:aff id="aff3">Department of Cell Biology, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Cell Biology, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Van Dieren, Brenda" sort="Van Dieren, Brenda" uniqKey="Van Dieren B" first="Brenda" last="Van Dieren">Brenda Van Dieren</name><affiliation wicri:level="4"><nlm:aff id="aff4">Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName><orgName type="university">Université d'Utrecht</orgName></affiliation></author><author><name sortKey="Widagdo, W" sort="Widagdo, W" uniqKey="Widagdo W" first="W." last="Widagdo">W. Widagdo</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Lamers, Mart M" sort="Lamers, Mart M" uniqKey="Lamers M" first="Mart M." last="Lamers">Mart M. Lamers</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Widjaja, Ivy" sort="Widjaja, Ivy" uniqKey="Widjaja I" first="Ivy" last="Widjaja">Ivy Widjaja</name><affiliation wicri:level="4"><nlm:aff id="aff4">Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName><orgName type="university">Université d'Utrecht</orgName></affiliation></author><author><name sortKey="Fernandez Delgado, Raul" sort="Fernandez Delgado, Raul" uniqKey="Fernandez Delgado R" first="Raul" last="Fernandez-Delgado">Raul Fernandez-Delgado</name><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Sola, Isabel" sort="Sola, Isabel" uniqKey="Sola I" first="Isabel" last="Sola">Isabel Sola</name><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Bensaid, Albert" sort="Bensaid, Albert" uniqKey="Bensaid A" first="Albert" last="Bensaid">Albert Bensaid</name><affiliation wicri:level="2"><nlm:aff id="aff5">Institut de Recerca i Tecnologia Agroalimentàries (IRTA), Centre de Recerca en Sanitat Animal [CReSA, IRTA–Universitat Autònoma de Barcelona (UAB)], Campus de la UAB, 08193 Bellaterra, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Institut de Recerca i Tecnologia Agroalimentàries (IRTA), Centre de Recerca en Sanitat Animal [CReSA, IRTA–Universitat Autònoma de Barcelona (UAB)], Campus de la UAB, 08193 Bellaterra</wicri:regionArea><placeName><region nuts="2" type="communauté">Catalogne</region></placeName></affiliation></author><author><name sortKey="Koopmans, Marion P" sort="Koopmans, Marion P" uniqKey="Koopmans M" first="Marion P." last="Koopmans">Marion P. Koopmans</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Segales, Joaquim" sort="Segales, Joaquim" uniqKey="Segales J" first="Joaquim" last="Segalés">Joaquim Segalés</name><affiliation wicri:level="2"><nlm:aff id="aff6">UAB, CReSA (IRTA-UAB), Campus de la UAB, 08193 Bellaterra, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>UAB, CReSA (IRTA-UAB), Campus de la UAB, 08193 Bellaterra</wicri:regionArea><placeName><region nuts="2" type="communauté">Catalogne</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff7">Departament de Sanitat i Anatomia Animals, Facultat de Veterinària, UAB, 08193 Bellaterra, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Departament de Sanitat i Anatomia Animals, Facultat de Veterinària, UAB, 08193 Bellaterra</wicri:regionArea><placeName><region nuts="2" type="communauté">Catalogne</region></placeName></affiliation></author><author><name sortKey="Osterhaus, Albert D M E" sort="Osterhaus, Albert D M E" uniqKey="Osterhaus A" first="Albert D. M. E." last="Osterhaus">Albert D. M. E. Osterhaus</name><affiliation wicri:level="3"><nlm:aff id="aff8">Artemis One Health, Utrecht, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Artemis One Health, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff9">Center for Infection Medicine and Zoonoses Research, University of Veterinary Medicine, Hannover, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Center for Infection Medicine and Zoonoses Research, University of Veterinary Medicine, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Bosch, Berend Jan" sort="Bosch, Berend Jan" uniqKey="Bosch B" first="Berend Jan" last="Bosch">Berend Jan Bosch</name><affiliation wicri:level="4"><nlm:aff id="aff4">Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName><orgName type="university">Université d'Utrecht</orgName></affiliation></author><author><name sortKey="Enjuanes, Luis" sort="Enjuanes, Luis" uniqKey="Enjuanes L" first="Luis" last="Enjuanes">Luis Enjuanes</name><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Haagmans, Bart L" sort="Haagmans, Bart L" uniqKey="Haagmans B" first="Bart L." last="Haagmans">Bart L. Haagmans</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author></analytic><series><title level="j">Science Advances</title><idno type="eISSN">2375-2548</idno><imprint><date when="2018">2018</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Antibodies, Neutralizing (administration & dosage)</term><term>Antibodies, Neutralizing (biosynthesis)</term><term>Antibodies, Neutralizing (immunology)</term><term>Antibodies, Viral (administration & dosage)</term><term>Antibodies, Viral (biosynthesis)</term><term>Antibodies, Viral (immunology)</term><term>Camelus</term><term>Coronavirus Infections (immunology)</term><term>Coronavirus Infections (prevention & control)</term><term>Coronavirus Infections (virology)</term><term>Female</term><term>Humans</term><term>Male</term><term>Mice</term><term>Middle East Respiratory Syndrome Coronavirus (immunology)</term><term>Neutralization Tests</term><term>Protein Binding</term><term>Single-Domain Antibodies</term><term>Virus Internalization (drug effects)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Anticorps antiviraux (administration et posologie)</term><term>Anticorps antiviraux (biosynthèse)</term><term>Anticorps antiviraux (immunologie)</term><term>Anticorps neutralisants (administration et posologie)</term><term>Anticorps neutralisants (biosynthèse)</term><term>Anticorps neutralisants (immunologie)</term><term>Anticorps à domaine unique</term><term>Chameaux</term><term>Coronavirus du syndrome respiratoire du Moyen-Orient (immunologie)</term><term>Femelle</term><term>Humains</term><term>Infections à coronavirus ()</term><term>Infections à coronavirus (immunologie)</term><term>Infections à coronavirus (virologie)</term><term>Liaison aux protéines</term><term>Mâle</term><term>Pénétration virale ()</term><term>Souris</term><term>Tests de neutralisation</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Antibodies, Neutralizing</term><term>Antibodies, Viral</term></keywords><keywords scheme="MESH" type="chemical" qualifier="biosynthesis" xml:lang="en"><term>Antibodies, Neutralizing</term><term>Antibodies, Viral</term></keywords><keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Antibodies, Neutralizing</term><term>Antibodies, Viral</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Anticorps antiviraux</term><term>Anticorps neutralisants</term></keywords><keywords scheme="MESH" qualifier="biosynthèse" xml:lang="fr"><term>Anticorps antiviraux</term><term>Anticorps neutralisants</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Virus Internalization</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Anticorps antiviraux</term><term>Anticorps neutralisants</term><term>Coronavirus du syndrome respiratoire du Moyen-Orient</term><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Coronavirus Infections</term><term>Middle East Respiratory Syndrome Coronavirus</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Coronavirus Infections</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Camelus</term><term>Female</term><term>Humans</term><term>Male</term><term>Mice</term><term>Neutralization Tests</term><term>Protein Binding</term><term>Single-Domain Antibodies</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Anticorps à domaine unique</term><term>Chameaux</term><term>Femelle</term><term>Humains</term><term>Infections à coronavirus</term><term>Liaison aux protéines</term><term>Mâle</term><term>Pénétration virale</term><term>Souris</term><term>Tests de neutralisation</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Dromedary camel heavy chain–only antibodies may provide novel intervention strategies against MERS coronavirus.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Zaki, A M" uniqKey="Zaki A">A. M. Zaki</name></author><author><name sortKey="Van Boheemen, S" uniqKey="Van Boheemen S">S. van Boheemen</name></author><author><name sortKey="Bestebroer, T M" uniqKey="Bestebroer T">T. M. Bestebroer</name></author><author><name sortKey="Osterhaus, A D M E" uniqKey="Osterhaus A">A. D. M. E. Osterhaus</name></author><author><name sortKey="Fouchier, R A M" uniqKey="Fouchier R">R. A. M. Fouchier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cauchemez, S" uniqKey="Cauchemez S">S. Cauchemez</name></author><author><name sortKey="Nouvellet, P" uniqKey="Nouvellet P">P. Nouvellet</name></author><author><name sortKey="Cori, A" uniqKey="Cori A">A. Cori</name></author><author><name sortKey="Jombart, T" uniqKey="Jombart T">T. Jombart</name></author><author><name sortKey="Garske, T" uniqKey="Garske T">T. Garske</name></author><author><name sortKey="Clapham, H" uniqKey="Clapham H">H. Clapham</name></author><author><name sortKey="Moore, S" uniqKey="Moore S">S. Moore</name></author><author><name sortKey="Mills, H L" uniqKey="Mills H">H. L. Mills</name></author><author><name sortKey="Salje, H" uniqKey="Salje H">H. Salje</name></author><author><name sortKey="Collins, C" uniqKey="Collins C">C. Collins</name></author><author><name sortKey="Rodriquez Barraquer, I" uniqKey="Rodriquez Barraquer I">I. Rodriquez-Barraquer</name></author><author><name sortKey="Riley, S" uniqKey="Riley S">S. Riley</name></author><author><name sortKey="Truelove, S" uniqKey="Truelove S">S. Truelove</name></author><author><name sortKey="Algarni, H" uniqKey="Algarni H">H. Algarni</name></author><author><name sortKey="Alhakeem, R" uniqKey="Alhakeem R">R. Alhakeem</name></author><author><name sortKey="Alharbi, K" uniqKey="Alharbi K">K. AlHarbi</name></author><author><name sortKey="Turkistani, A" uniqKey="Turkistani A">A. Turkistani</name></author><author><name sortKey="Aguas, R J" uniqKey="Aguas R">R. J. Aguas</name></author><author><name sortKey="Cummings, D A T" uniqKey="Cummings D">D. A. T. Cummings</name></author><author><name sortKey="Van Kerkhove, M D" uniqKey="Van Kerkhove M">M. D. Van Kerkhove</name></author><author><name sortKey="Donnelly, C A" uniqKey="Donnelly C">C. A. Donnelly</name></author><author><name sortKey="Lessler, J" uniqKey="Lessler J">J. Lessler</name></author><author><name sortKey="Fraser, C" uniqKey="Fraser C">C. Fraser</name></author><author><name sortKey="Al Barrak, A" uniqKey="Al Barrak A">A. Al-Barrak</name></author><author><name sortKey="Ferguson, N M" uniqKey="Ferguson N">N. M. Ferguson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Raj, V S" uniqKey="Raj V">V. S. Raj</name></author><author><name sortKey="Farag, E A B A" uniqKey="Farag E">E. A. B. A. Farag</name></author><author><name sortKey="Reusken, C B E M" uniqKey="Reusken C">C. B. E. M. Reusken</name></author><author><name sortKey="Lamers, M M" uniqKey="Lamers M">M. M. Lamers</name></author><author><name sortKey="Pas, S D" uniqKey="Pas S">S. D. Pas</name></author><author><name sortKey="Voermans, J" uniqKey="Voermans J">J. Voermans</name></author><author><name sortKey="Smits, S L" uniqKey="Smits S">S. L. Smits</name></author><author><name sortKey="Osterhaus, A D M E" uniqKey="Osterhaus A">A. D. M. E. Osterhaus</name></author><author><name sortKey="Al Mawlawi, N" uniqKey="Al Mawlawi N">N. Al-Mawlawi</name></author><author><name sortKey="Al Romaihi, H E" uniqKey="Al Romaihi H">H. E. Al-Romaihi</name></author><author><name sortKey="Alhajri, M M" uniqKey="Alhajri M">M. M. AlHajri</name></author><author><name sortKey="El Sayed, A M" uniqKey="El Sayed A">A. M. El-Sayed</name></author><author><name sortKey="Mohran, K A" uniqKey="Mohran K">K. A. Mohran</name></author><author><name sortKey="Ghobashy, H" uniqKey="Ghobashy H">H. Ghobashy</name></author><author><name sortKey="Alhajri, F" uniqKey="Alhajri F">F. Alhajri</name></author><author><name sortKey="Al Thani, M" uniqKey="Al Thani M">M. Al-Thani</name></author><author><name sortKey="Al Marri, S A" uniqKey="Al Marri S">S. A. Al-Marri</name></author><author><name sortKey="El Maghraby, M M" uniqKey="El Maghraby M">M. M. El-Maghraby</name></author><author><name sortKey="Koopmans, M P G" uniqKey="Koopmans M">M. P. G. Koopmans</name></author><author><name sortKey="Haagmans, Bart L" uniqKey="Haagmans B">Bart L. Haagmans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cotten, M" uniqKey="Cotten M">M. Cotten</name></author><author><name sortKey="Watson, S J" uniqKey="Watson S">S. J. Watson</name></author><author><name sortKey="Kellam, P" uniqKey="Kellam P">P. Kellam</name></author><author><name sortKey="Al Rabeeah, A A" uniqKey="Al Rabeeah A">A. A. Al-Rabeeah</name></author><author><name sortKey="Makhdoom, H Q" uniqKey="Makhdoom H">H. Q. Makhdoom</name></author><author><name sortKey="Assiri, A" uniqKey="Assiri A">A. Assiri</name></author><author><name sortKey="Al Tawfiq, J A" uniqKey="Al Tawfiq J">J. A. Al-Tawfiq</name></author><author><name sortKey="Alhakeem, R F" uniqKey="Alhakeem R">R. F. Alhakeem</name></author><author><name sortKey="Madani, H" uniqKey="Madani H">H. Madani</name></author><author><name sortKey="Alrabiah, F A" uniqKey="Alrabiah F">F. A. AlRabiah</name></author><author><name sortKey="Hajjar, S A" uniqKey="Hajjar S">S. A. Hajjar</name></author><author><name sortKey="Al Nassir, W N" uniqKey="Al Nassir W">W. N. Al-nassir</name></author><author><name sortKey="Albarrak, A" uniqKey="Albarrak A">A. Albarrak</name></author><author><name sortKey="Flemban, H" uniqKey="Flemban H">H. Flemban</name></author><author><name sortKey="Balkhy, H H" uniqKey="Balkhy H">H. H. Balkhy</name></author><author><name sortKey="Alsubaie, S" uniqKey="Alsubaie S">S. Alsubaie</name></author><author><name sortKey="Palser, A L" uniqKey="Palser A">A. L. Palser</name></author><author><name sortKey="Gall, A" uniqKey="Gall A">A. Gall</name></author><author><name sortKey="Memish, Z A" uniqKey="Memish Z">Z. A. Memish</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tang, X C" uniqKey="Tang X">X.-C. Tang</name></author><author><name sortKey="Agnihothram, S S" uniqKey="Agnihothram S">S. S. Agnihothram</name></author><author><name sortKey="Jiao, Y" uniqKey="Jiao Y">Y. Jiao</name></author><author><name sortKey="Stanhope, J" uniqKey="Stanhope J">J. Stanhope</name></author><author><name sortKey="Graham, R L" uniqKey="Graham R">R. L. Graham</name></author><author><name sortKey="Peterson, E C" uniqKey="Peterson E">E. C. Peterson</name></author><author><name sortKey="Avnir, Y" uniqKey="Avnir Y">Y. Avnir</name></author><author><name sortKey="St Clair Tallarico, A" uniqKey="St Clair Tallarico A">A. St. Clair Tallarico</name></author><author><name sortKey="Sheehan, J" uniqKey="Sheehan J">J. Sheehan</name></author><author><name sortKey="Zhu, Q" uniqKey="Zhu Q">Q. Zhu</name></author><author><name sortKey="Baric, R S" uniqKey="Baric R">R. S. Baric</name></author><author><name sortKey="Marasco, W A" uniqKey="Marasco W">W. A. Marasco</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Corti, D" uniqKey="Corti D">D. Corti</name></author><author><name sortKey="Zhao, J" uniqKey="Zhao J">J. Zhao</name></author><author><name sortKey="Pedotti, M" uniqKey="Pedotti M">M. Pedotti</name></author><author><name sortKey="Simonelli, L" uniqKey="Simonelli L">L. Simonelli</name></author><author><name sortKey="Agnihothram, S" uniqKey="Agnihothram S">S. Agnihothram</name></author><author><name sortKey="Fett, C" uniqKey="Fett C">C. Fett</name></author><author><name sortKey="Fernandez Rodriguez, B" uniqKey="Fernandez Rodriguez B">B. Fernandez-Rodriguez</name></author><author><name sortKey="Foglierini, M" uniqKey="Foglierini M">M. Foglierini</name></author><author><name sortKey="Agatic, G" uniqKey="Agatic G">G. Agatic</name></author><author><name sortKey="Vanzetta, F" uniqKey="Vanzetta F">F. Vanzetta</name></author><author><name sortKey="Gopal, R" uniqKey="Gopal R">R. Gopal</name></author><author><name sortKey="Langrish, C J" uniqKey="Langrish C">C. J. Langrish</name></author><author><name sortKey="Barrett, N A" uniqKey="Barrett N">N. A. Barrett</name></author><author><name sortKey="Sallusto, F" uniqKey="Sallusto F">F. Sallusto</name></author><author><name sortKey="Baric, R S" uniqKey="Baric R">R. S. Baric</name></author><author><name sortKey="Varani, L" uniqKey="Varani L">L. Varani</name></author><author><name sortKey="Zambon, M" uniqKey="Zambon M">M. Zambon</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S. Perlman</name></author><author><name sortKey="Lanzavecchia, A" uniqKey="Lanzavecchia A">A. Lanzavecchia</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pascal, K E" uniqKey="Pascal K">K. E. Pascal</name></author><author><name sortKey="Coleman, C M" uniqKey="Coleman C">C. M. Coleman</name></author><author><name sortKey="Mujica, A O" uniqKey="Mujica A">A. O. Mujica</name></author><author><name sortKey="Kamat, V" uniqKey="Kamat V">V. Kamat</name></author><author><name sortKey="Badithe, A" uniqKey="Badithe A">A. Badithe</name></author><author><name sortKey="Fairhurst, J" uniqKey="Fairhurst J">J. Fairhurst</name></author><author><name sortKey="Hunt, C" uniqKey="Hunt C">C. Hunt</name></author><author><name sortKey="Strein, J" uniqKey="Strein J">J. Strein</name></author><author><name sortKey="Berrebi, A" uniqKey="Berrebi A">A. Berrebi</name></author><author><name sortKey="Sisk, J M" uniqKey="Sisk J">J. M. Sisk</name></author><author><name sortKey="Matthews, K L" uniqKey="Matthews K">K. L. Matthews</name></author><author><name sortKey="Babb, R" uniqKey="Babb R">R. Babb</name></author><author><name sortKey="Chen, G" uniqKey="Chen G">G. Chen</name></author><author><name sortKey="Lai, K M V" uniqKey="Lai K">K.-M. V. Lai</name></author><author><name sortKey="Huang, T T" uniqKey="Huang T">T. T. Huang</name></author><author><name sortKey="Olson, W" uniqKey="Olson W">W. Olson</name></author><author><name sortKey="Yancopoulos, G D" uniqKey="Yancopoulos G">G. D. Yancopoulos</name></author><author><name sortKey="Stahl, N" uniqKey="Stahl N">N. Stahl</name></author><author><name sortKey="Frieman, M B" uniqKey="Frieman M">M. B. Frieman</name></author><author><name sortKey="Kyratsous, C A" uniqKey="Kyratsous C">C. A. Kyratsous</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Raj, V S" uniqKey="Raj V">V. S. Raj</name></author><author><name sortKey="Mou, H" uniqKey="Mou H">H. Mou</name></author><author><name sortKey="Smits, S L" uniqKey="Smits S">S. L. Smits</name></author><author><name sortKey="Dekkers, D H W" uniqKey="Dekkers D">D. H. W. Dekkers</name></author><author><name sortKey="Muller, M A" uniqKey="Muller M">M. A. Müller</name></author><author><name sortKey="Dijkman, R" uniqKey="Dijkman R">R. Dijkman</name></author><author><name sortKey="Muth, D" uniqKey="Muth D">D. Muth</name></author><author><name sortKey="Demmers, J A A" uniqKey="Demmers J">J. A. A. Demmers</name></author><author><name sortKey="Zaki, A" uniqKey="Zaki A">A. Zaki</name></author><author><name sortKey="Fouchier, R A M" uniqKey="Fouchier R">R. A. M. Fouchier</name></author><author><name sortKey="Thiel, V" uniqKey="Thiel V">V. Thiel</name></author><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author><author><name sortKey="Rottier, P J M" uniqKey="Rottier P">P. J. M. Rottier</name></author><author><name sortKey="Osterhaus, A D M E" uniqKey="Osterhaus A">A. D. M. E. Osterhaus</name></author><author><name sortKey="Bosch, B J" uniqKey="Bosch B">B. J. Bosch</name></author><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B. L. Haagmans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mou, H" uniqKey="Mou H">H. Mou</name></author><author><name sortKey="Raj, V S" uniqKey="Raj V">V. S. Raj</name></author><author><name sortKey="Van Kuppeveld, F J M" uniqKey="Van Kuppeveld F">F. J. M. van Kuppeveld</name></author><author><name sortKey="Rottier, P J M" uniqKey="Rottier P">P. J. M. Rottier</name></author><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B. L. Haagmans</name></author><author><name sortKey="Bosch, B J" uniqKey="Bosch B">B. J. Bosch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Al Amri, S S" uniqKey="Al Amri S">S. S. Al-amri</name></author><author><name sortKey="Abbas, A T" uniqKey="Abbas A">A. T. Abbas</name></author><author><name sortKey="Siddiq, L A" uniqKey="Siddiq L">L. A. Siddiq</name></author><author><name sortKey="Alghamdi, A" uniqKey="Alghamdi A">A. Alghamdi</name></author><author><name sortKey="Sanki, M A" uniqKey="Sanki M">M. A. Sanki</name></author><author><name sortKey="Al Muhanna, M K" uniqKey="Al Muhanna M">M. K. Al-Muhanna</name></author><author><name sortKey="Alhabbab, R Y" uniqKey="Alhabbab R">R. Y. Alhabbab</name></author><author><name sortKey="Azhar, E I" uniqKey="Azhar E">E. I. Azhar</name></author><author><name sortKey="Li, X" uniqKey="Li X">X. Li</name></author><author><name sortKey="Hashem, A M" uniqKey="Hashem A">A. M. Hashem</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, Y" uniqKey="Li Y">Y. Li</name></author><author><name sortKey="Wan, Y" uniqKey="Wan Y">Y. Wan</name></author><author><name sortKey="Liu, P" uniqKey="Liu P">P. Liu</name></author><author><name sortKey="Zhao, J" uniqKey="Zhao J">J. Zhao</name></author><author><name sortKey="Lu, G" uniqKey="Lu G">G. Lu</name></author><author><name sortKey="Qi, J" uniqKey="Qi J">J. Qi</name></author><author><name sortKey="Wang, Q" uniqKey="Wang Q">Q. Wang</name></author><author><name sortKey="Lu, X" uniqKey="Lu X">X. Lu</name></author><author><name sortKey="Wu, Y" uniqKey="Wu Y">Y. Wu</name></author><author><name sortKey="Liu, W" uniqKey="Liu W">W. Liu</name></author><author><name sortKey="Zhang, B" uniqKey="Zhang B">B. Zhang</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.-Y. Yuen</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S. Perlman</name></author><author><name sortKey="Gao, G F" uniqKey="Gao G">G. F. Gao</name></author><author><name sortKey="Yan, J" uniqKey="Yan J">J. Yan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jiang, L" uniqKey="Jiang L">L. Jiang</name></author><author><name sortKey="Wang, N" uniqKey="Wang N">N. Wang</name></author><author><name sortKey="Zuo, T" uniqKey="Zuo T">T. Zuo</name></author><author><name sortKey="Shi, X" uniqKey="Shi X">X. Shi</name></author><author><name sortKey="Poon, K M V" uniqKey="Poon K">K.-M. V. Poon</name></author><author><name sortKey="Wu, Y" uniqKey="Wu Y">Y. Wu</name></author><author><name sortKey="Gao, F" uniqKey="Gao F">F. Gao</name></author><author><name sortKey="Li, D" uniqKey="Li D">D. Li</name></author><author><name sortKey="Wang, R" uniqKey="Wang R">R. Wang</name></author><author><name sortKey="Guo, J" uniqKey="Guo J">J. Guo</name></author><author><name sortKey="Fu, L" uniqKey="Fu L">L. Fu</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.-Y. Yuen</name></author><author><name sortKey="Zheng, B J" uniqKey="Zheng B">B.-J. Zheng</name></author><author><name sortKey="Wang, X" uniqKey="Wang X">X. Wang</name></author><author><name sortKey="Zhang, L" uniqKey="Zhang L">L. Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Agrawal, A S" uniqKey="Agrawal A">A. S. Agrawal</name></author><author><name sortKey="Ying, T" uniqKey="Ying T">T. Ying</name></author><author><name sortKey="Tao, X" uniqKey="Tao X">X. Tao</name></author><author><name sortKey="Garron, T" uniqKey="Garron T">T. Garron</name></author><author><name sortKey="Algaissi, A" uniqKey="Algaissi A">A. Algaissi</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y. Wang</name></author><author><name sortKey="Wang, L" uniqKey="Wang L">L. Wang</name></author><author><name sortKey="Peng, B H" uniqKey="Peng B">B.-H. Peng</name></author><author><name sortKey="Jiang, S" uniqKey="Jiang S">S. Jiang</name></author><author><name sortKey="Dimitrov, D S" uniqKey="Dimitrov D">D. S. Dimitrov</name></author><author><name sortKey="Tseng, C T K" uniqKey="Tseng C">C.-T. K. Tseng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yu, X" uniqKey="Yu X">X. Yu</name></author><author><name sortKey="Zhang, S" uniqKey="Zhang S">S. Zhang</name></author><author><name sortKey="Jiang, L" uniqKey="Jiang L">L. Jiang</name></author><author><name sortKey="Cui, Y" uniqKey="Cui Y">Y. Cui</name></author><author><name sortKey="Li, D" uniqKey="Li D">D. Li</name></author><author><name sortKey="Wang, D" uniqKey="Wang D">D. Wang</name></author><author><name sortKey="Wang, N" uniqKey="Wang N">N. Wang</name></author><author><name sortKey="Fu, L" uniqKey="Fu L">L. Fu</name></author><author><name sortKey="Shi, X" uniqKey="Shi X">X. Shi</name></author><author><name sortKey="Li, Z" uniqKey="Li Z">Z. Li</name></author><author><name sortKey="Zhang, L" uniqKey="Zhang L">L. Zhang</name></author><author><name sortKey="Wang, X" uniqKey="Wang X">X. Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chames, P" uniqKey="Chames P">P. Chames</name></author><author><name sortKey="Van Regenmortel, M" uniqKey="Van Regenmortel M">M. Van Regenmortel</name></author><author><name sortKey="Weiss, E" uniqKey="Weiss E">E. Weiss</name></author><author><name sortKey="Baty, D" uniqKey="Baty D">D. Baty</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Spadiut, O" uniqKey="Spadiut O">O. Spadiut</name></author><author><name sortKey="Capone, S" uniqKey="Capone S">S. Capone</name></author><author><name sortKey="Krainer, F" uniqKey="Krainer F">F. Krainer</name></author><author><name sortKey="Glieder, A" uniqKey="Glieder A">A. Glieder</name></author><author><name sortKey="Herwig, C" uniqKey="Herwig C">C. Herwig</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Irani, V" uniqKey="Irani V">V. Irani</name></author><author><name sortKey="Guy, A J" uniqKey="Guy A">A. J. Guy</name></author><author><name sortKey="Andrew, D" uniqKey="Andrew D">D. Andrew</name></author><author><name sortKey="Beeson, J G" uniqKey="Beeson J">J. G. Beeson</name></author><author><name sortKey="Ramsland, P A" uniqKey="Ramsland P">P. A. Ramsland</name></author><author><name sortKey="Richards, J S" uniqKey="Richards J">J. S. Richards</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hamers Casterman, C" uniqKey="Hamers Casterman C">C. Hamers-Casterman</name></author><author><name sortKey="Atarhouch, T" uniqKey="Atarhouch T">T. Atarhouch</name></author><author><name sortKey="Muyldermans, S" uniqKey="Muyldermans S">S. Muyldermans</name></author><author><name sortKey="Robinson, G" uniqKey="Robinson G">G. Robinson</name></author><author><name sortKey="Hammers, C" uniqKey="Hammers C">C. Hammers</name></author><author><name sortKey="Songa, E B" uniqKey="Songa E">E. B. Songa</name></author><author><name sortKey="Bendahman, N" uniqKey="Bendahman N">N. Bendahman</name></author><author><name sortKey="Hammers, R" uniqKey="Hammers R">R. Hammers</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Muyldermans, S" uniqKey="Muyldermans S">S. Muyldermans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Genst, E" uniqKey="De Genst E">E. De Genst</name></author><author><name sortKey="Silence, K" uniqKey="Silence K">K. Silence</name></author><author><name sortKey="Decanniere, K" uniqKey="Decanniere K">K. Decanniere</name></author><author><name sortKey="Conrath, K" uniqKey="Conrath K">K. Conrath</name></author><author><name sortKey="Loris, R" uniqKey="Loris R">R. Loris</name></author><author><name sortKey="Kinne, J" uniqKey="Kinne J">J. Kinne</name></author><author><name sortKey="Muyldermans, S" uniqKey="Muyldermans S">S. Muyldermans</name></author><author><name sortKey="Wyns, L" uniqKey="Wyns L">L. Wyns</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rothbauer, U" uniqKey="Rothbauer U">U. Rothbauer</name></author><author><name sortKey="Zolghadr, K" uniqKey="Zolghadr K">K. Zolghadr</name></author><author><name sortKey="Tillib, S" uniqKey="Tillib S">S. Tillib</name></author><author><name sortKey="Nowak, D" uniqKey="Nowak D">D. Nowak</name></author><author><name sortKey="Schermelleh, L" uniqKey="Schermelleh L">L. Schermelleh</name></author><author><name sortKey="Gahl, A" uniqKey="Gahl A">A. Gahl</name></author><author><name sortKey="Backmann, N" uniqKey="Backmann N">N. Backmann</name></author><author><name sortKey="Conrath, K" uniqKey="Conrath K">K. Conrath</name></author><author><name sortKey="Muyldermans, S" uniqKey="Muyldermans S">S. Muyldermans</name></author><author><name sortKey="Cardoso, M C" uniqKey="Cardoso M">M. C. Cardoso</name></author><author><name sortKey="Leonhardt, H" uniqKey="Leonhardt H">H. Leonhardt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hassanzadeh Ghassabeh, G" uniqKey="Hassanzadeh Ghassabeh G">G. Hassanzadeh-Ghassabeh</name></author><author><name sortKey="Devoogdt, N" uniqKey="Devoogdt N">N. Devoogdt</name></author><author><name sortKey="De Pauw, P" uniqKey="De Pauw P">P. De Pauw</name></author><author><name sortKey="Vincke, C" uniqKey="Vincke C">C. Vincke</name></author><author><name sortKey="Muyldermans, S" uniqKey="Muyldermans S">S. Muyldermans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Peyvandi, F" uniqKey="Peyvandi F">F. Peyvandi</name></author><author><name sortKey="Scully, M" uniqKey="Scully M">M. Scully</name></author><author><name sortKey="Kremer Hovinga, J A" uniqKey="Kremer Hovinga J">J. A. Kremer Hovinga</name></author><author><name sortKey="Cataland, S" uniqKey="Cataland S">S. Cataland</name></author><author><name sortKey="Knobl, P" uniqKey="Knobl P">P. Knöbl</name></author><author><name sortKey="Wu, H" uniqKey="Wu H">H. Wu</name></author><author><name sortKey="Artoni, A" uniqKey="Artoni A">A. Artoni</name></author><author><name sortKey="Westwood, J P" uniqKey="Westwood J">J. P. Westwood</name></author><author><name sortKey="Mansouri Taleghani, M" uniqKey="Mansouri Taleghani M">M. Mansouri Taleghani</name></author><author><name sortKey="Jilma, B" uniqKey="Jilma B">B. Jilma</name></author><author><name sortKey="Callewaert, F" uniqKey="Callewaert F">F. Callewaert</name></author><author><name sortKey="Ulrichts, H" uniqKey="Ulrichts H">H. Ulrichts</name></author><author><name sortKey="Duby, C" uniqKey="Duby C">C. Duby</name></author><author><name sortKey="Tersago, D" uniqKey="Tersago D">D. Tersago</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vanlandschoot, P" uniqKey="Vanlandschoot P">P. Vanlandschoot</name></author><author><name sortKey="Stortelers, C" uniqKey="Stortelers C">C. Stortelers</name></author><author><name sortKey="Beirnaert, E" uniqKey="Beirnaert E">E. Beirnaert</name></author><author><name sortKey="Iba Ez, L I" uniqKey="Iba Ez L">L. I. Ibañez</name></author><author><name sortKey="Schepens, B" uniqKey="Schepens B">B. Schepens</name></author><author><name sortKey="Depla, E" uniqKey="Depla E">E. Depla</name></author><author><name sortKey="Saelens, X" uniqKey="Saelens X">X. Saelens</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Farag, E A B A" uniqKey="Farag E">E. A. B. A. Farag</name></author><author><name sortKey="Reusken, C B E M" uniqKey="Reusken C">C. B. E. M. Reusken</name></author><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B. L. Haagmans</name></author><author><name sortKey="Mohran, K A" uniqKey="Mohran K">K. A. Mohran</name></author><author><name sortKey="Stalin Raj, V" uniqKey="Stalin Raj V">V. Stalin Raj</name></author><author><name sortKey="Pas, S D" uniqKey="Pas S">S. D. Pas</name></author><author><name sortKey="Voermans, J" uniqKey="Voermans J">J. Voermans</name></author><author><name sortKey="Smits, S L" uniqKey="Smits S">S. L. Smits</name></author><author><name sortKey="Godeke, G J" uniqKey="Godeke G">G.-J. Godeke</name></author><author><name sortKey="Al Hajri, M M" uniqKey="Al Hajri M">M. M. Al-Hajri</name></author><author><name sortKey="Alhajri, F H" uniqKey="Alhajri F">F. H. Alhajri</name></author><author><name sortKey="Al Romaihi, H E" uniqKey="Al Romaihi H">H. E. Al-Romaihi</name></author><author><name sortKey="Ghobashy, H" uniqKey="Ghobashy H">H. Ghobashy</name></author><author><name sortKey="El Maghraby, M M" uniqKey="El Maghraby M">M. M. El-Maghraby</name></author><author><name sortKey="El Sayed, A M" uniqKey="El Sayed A">A. M. El-Sayed</name></author><author><name sortKey="Al Thani, M H J" uniqKey="Al Thani M">M. H. J. Al Thani</name></author><author><name sortKey="Al Marri, S" uniqKey="Al Marri S">S. Al-Marri</name></author><author><name sortKey="Koopmans, M P G" uniqKey="Koopmans M">M. P. G. Koopmans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Reusken, C B E M" uniqKey="Reusken C">C. B. E. M. Reusken</name></author><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B. L. Haagmans</name></author><author><name sortKey="Muller, M A" uniqKey="Muller M">M. A. Müller</name></author><author><name sortKey="Gutierrez, C" uniqKey="Gutierrez C">C. Gutierrez</name></author><author><name sortKey="Godeke, G J" uniqKey="Godeke G">G.-J. Godeke</name></author><author><name sortKey="Meyer, B" uniqKey="Meyer B">B. Meyer</name></author><author><name sortKey="Muth, D" uniqKey="Muth D">D. Muth</name></author><author><name sortKey="Stalin Raj, V" uniqKey="Stalin Raj V">V. Stalin Raj</name></author><author><name sortKey="Smits De Vries, L" uniqKey="Smits De Vries L">L. Smits-De Vries</name></author><author><name sortKey="Corman, V M" uniqKey="Corman V">V. M. Corman</name></author><author><name sortKey="Drexler, J F" uniqKey="Drexler J">J.-F. Drexler</name></author><author><name sortKey="Smits, S L" uniqKey="Smits S">S. L. Smits</name></author><author><name sortKey="El Tahir, Y E" uniqKey="El Tahir Y">Y. E. El Tahir</name></author><author><name sortKey="De Sousa, R" uniqKey="De Sousa R">R. De Sousa</name></author><author><name sortKey="Van Beek, J" uniqKey="Van Beek J">J. van Beek</name></author><author><name sortKey="Nowotny, N" uniqKey="Nowotny N">N. Nowotny</name></author><author><name sortKey="Van Maanen, K" uniqKey="Van Maanen K">K. van Maanen</name></author><author><name sortKey="Hidalgo Hermoso, E" uniqKey="Hidalgo Hermoso E">E. Hidalgo-Hermoso</name></author><author><name sortKey="Koopmans, M P G" uniqKey="Koopmans M">M. P. G. Koopmans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Muller, M A" uniqKey="Muller M">M. A. Müller</name></author><author><name sortKey="Corman, V M" uniqKey="Corman V">V. M. Corman</name></author><author><name sortKey="Jores, J" uniqKey="Jores J">J. Jores</name></author><author><name sortKey="Meyer, B" uniqKey="Meyer B">B. Meyer</name></author><author><name sortKey="Younan, M" uniqKey="Younan M">M. Younan</name></author><author><name sortKey="Liljander, A M" uniqKey="Liljander A">A. M. Liljander</name></author><author><name sortKey="Bosch, B J" uniqKey="Bosch B">B.-J. Bosch</name></author><author><name sortKey="Lattwein, E" uniqKey="Lattwein E">E. Lattwein</name></author><author><name sortKey="Hilali, M" uniqKey="Hilali M">M. Hilali</name></author><author><name sortKey="Musa, B E" uniqKey="Musa B">B. E. Musa</name></author><author><name sortKey="Bornstein, S" uniqKey="Bornstein S">S. Bornstein</name></author><author><name sortKey="Park, S S" uniqKey="Park S">S. S. Park</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B. L. Haagmans</name></author><author><name sortKey="Van Den Brand, J M A" uniqKey="Van Den Brand J">J. M. A. van den Brand,</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pardon, E" uniqKey="Pardon E">E. Pardon</name></author><author><name sortKey="Laeremans, T" uniqKey="Laeremans T">T. Laeremans</name></author><author><name sortKey="Triest, S" uniqKey="Triest S">S. Triest</name></author><author><name sortKey="Rasmussen, S G F" uniqKey="Rasmussen S">S. G. F. Rasmussen</name></author><author><name sortKey="Wohlkonig, A" uniqKey="Wohlkonig A">A. Wohlkönig</name></author><author><name sortKey="Ruf, A" uniqKey="Ruf A">A. Ruf</name></author><author><name sortKey="Muyldermans, S" uniqKey="Muyldermans S">S. Muyldermans</name></author><author><name sortKey="Hol, W G J" uniqKey="Hol W">W. G. J. Hol</name></author><author><name sortKey="Kobilka, B K" uniqKey="Kobilka B">B. K. Kobilka</name></author><author><name sortKey="Steyaert, J" uniqKey="Steyaert J">J. Steyaert</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Chakravarty, R" uniqKey="Chakravarty R">R. Chakravarty</name></author><author><name sortKey="Goel, S" uniqKey="Goel S">S. Goel</name></author><author><name sortKey="Cai, W" uniqKey="Cai W">W. Cai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, N" uniqKey="Wang N">N. Wang</name></author><author><name sortKey="Shi, X" uniqKey="Shi X">X. Shi</name></author><author><name sortKey="Jiang, L" uniqKey="Jiang L">L. Jiang</name></author><author><name sortKey="Zhang, S" uniqKey="Zhang S">S. Zhang</name></author><author><name sortKey="Wang, D" uniqKey="Wang D">D. Wang</name></author><author><name sortKey="Tong, P" uniqKey="Tong P">P. Tong</name></author><author><name sortKey="Guo, D" uniqKey="Guo D">D. Guo</name></author><author><name sortKey="Fu, L" uniqKey="Fu L">L. Fu</name></author><author><name sortKey="Cui, Y" uniqKey="Cui Y">Y. Cui</name></author><author><name sortKey="Liu, X" uniqKey="Liu X">X. Liu</name></author><author><name sortKey="Arledge, K C" uniqKey="Arledge K">K. C. Arledge</name></author><author><name sortKey="Chen, Y H" uniqKey="Chen Y">Y.-H. Chen</name></author><author><name sortKey="Zhang, L" uniqKey="Zhang L">L. Zhang</name></author><author><name sortKey="Wang, X" uniqKey="Wang X">X. Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lu, G" uniqKey="Lu G">G. Lu</name></author><author><name sortKey="Hu, Y" uniqKey="Hu Y">Y. Hu</name></author><author><name sortKey="Wang, Q" uniqKey="Wang Q">Q. Wang</name></author><author><name sortKey="Qi, J" uniqKey="Qi J">J. Qi</name></author><author><name sortKey="Gao, F" uniqKey="Gao F">F. Gao</name></author><author><name sortKey="Li, Y" uniqKey="Li Y">Y. Li</name></author><author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y. Zhang</name></author><author><name sortKey="Zhang, W" uniqKey="Zhang W">W. Zhang</name></author><author><name sortKey="Yuan, Y" uniqKey="Yuan Y">Y. Yuan</name></author><author><name sortKey="Bao, J" uniqKey="Bao J">J. Bao</name></author><author><name sortKey="Zhang, B" uniqKey="Zhang B">B. Zhang</name></author><author><name sortKey="Shi, Y" uniqKey="Shi Y">Y. Shi</name></author><author><name sortKey="Yan, J" uniqKey="Yan J">J. Yan</name></author><author><name sortKey="Gao, G F" uniqKey="Gao G">G. F. Gao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, K" uniqKey="Li K">K. Li</name></author><author><name sortKey="Wohlford Lenane, C" uniqKey="Wohlford Lenane C">C. Wohlford-Lenane</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S. Perlman</name></author><author><name sortKey="Zhao, J" uniqKey="Zhao J">J. Zhao</name></author><author><name sortKey="Jewell, A K" uniqKey="Jewell A">A. K. Jewell</name></author><author><name sortKey="Reznikov, L R" uniqKey="Reznikov L">L. R. Reznikov</name></author><author><name sortKey="Gibson Corley, K N" uniqKey="Gibson Corley K">K. N. Gibson-Corley</name></author><author><name sortKey="Meyerholz, D K" uniqKey="Meyerholz D">D. K. Meyerholz</name></author><author><name sortKey="Mccray, P B" uniqKey="Mccray P">P. B. McCray</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schmidt, F I" uniqKey="Schmidt F">F. I. Schmidt</name></author><author><name sortKey="Hanke, L" uniqKey="Hanke L">L. Hanke</name></author><author><name sortKey="Morin, B" uniqKey="Morin B">B. Morin</name></author><author><name sortKey="Brewer, R" uniqKey="Brewer R">R. Brewer</name></author><author><name sortKey="Brusic, V" uniqKey="Brusic V">V. Brusic</name></author><author><name sortKey="Whelan, S P J" uniqKey="Whelan S">S. P. J. Whelan</name></author><author><name sortKey="Ploegh, H L" uniqKey="Ploegh H">H. L. Ploegh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B. L. Haagmans</name></author><author><name sortKey="Al Dhahiry, S H S" uniqKey="Al Dhahiry S">S. H. S. Al Dhahiry</name></author><author><name sortKey="Reusken, C B E M" uniqKey="Reusken C">C. B. E. M Reusken</name></author><author><name sortKey="Stalin Raj, V" uniqKey="Stalin Raj V">V. Stalin Raj</name></author><author><name sortKey="Galiano, M" uniqKey="Galiano M">M. Galiano</name></author><author><name sortKey="Myers, R" uniqKey="Myers R">R. Myers</name></author><author><name sortKey="Godeke, G J" uniqKey="Godeke G">G.-J. Godeke</name></author><author><name sortKey="Jonges, M" uniqKey="Jonges M">M. Jonges</name></author><author><name sortKey="Farag, E" uniqKey="Farag E">E. Farag</name></author><author><name sortKey="Diab, A" uniqKey="Diab A">A. Diab</name></author><author><name sortKey="Ghobashy, H" uniqKey="Ghobashy H">H. Ghobashy</name></author><author><name sortKey="Alhajri, F" uniqKey="Alhajri F">F. Alhajri</name></author><author><name sortKey="Al Thani, M" uniqKey="Al Thani M">M. Al-Thani</name></author><author><name sortKey="Al Marri, S A" uniqKey="Al Marri S">S. A. Al-Marri</name></author><author><name sortKey="Al Romaihi, H E" uniqKey="Al Romaihi H">H. E. Al Romaihi</name></author><author><name sortKey="Khal, A A" uniqKey="Khal A">A. A. Khal</name></author><author><name sortKey="Bermingham, A" uniqKey="Bermingham A">A. Bermingham</name></author><author><name sortKey="Osterhaus, A D M E" uniqKey="Osterhaus A">A. D. M. E. Osterhaus</name></author><author><name sortKey="Koopmans, M P G" uniqKey="Koopmans M">M. P. G. Koopmans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Radbruch, A" uniqKey="Radbruch A">A. Radbruch</name></author><author><name sortKey="Muehlinghaus, G" uniqKey="Muehlinghaus G">G. Muehlinghaus</name></author><author><name sortKey="Luger, E O" uniqKey="Luger E">E. O. Luger</name></author><author><name sortKey="Inamine, A" uniqKey="Inamine A">A. Inamine</name></author><author><name sortKey="Smith, K G C" uniqKey="Smith K">K. G. C. Smith</name></author><author><name sortKey="Dorner, T" uniqKey="Dorner T">T. Dörner</name></author><author><name sortKey="Hiepe, F" uniqKey="Hiepe F">F. Hiepe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ellyard, J I" uniqKey="Ellyard J">J. I. Ellyard</name></author><author><name sortKey="Avery, D T" uniqKey="Avery D">D. T. Avery</name></author><author><name sortKey="Phan, T G" uniqKey="Phan T">T. G. Phan</name></author><author><name sortKey="Hare, N J" uniqKey="Hare N">N. J. Hare</name></author><author><name sortKey="Hodgkin, P D" uniqKey="Hodgkin P">P. D. Hodgkin</name></author><author><name sortKey="Tangye, S G" uniqKey="Tangye S">S. G. Tangye</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Paramithiotis, E" uniqKey="Paramithiotis E">E. Paramithiotis</name></author><author><name sortKey="Cooper, M D" uniqKey="Cooper M">M. D. Cooper</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Manz, R A" uniqKey="Manz R">R. A. Manz</name></author><author><name sortKey="Hauser, A E" uniqKey="Hauser A">A. E. Hauser</name></author><author><name sortKey="Hiepe, F" uniqKey="Hiepe F">F. Hiepe</name></author><author><name sortKey="Radbruch, A" uniqKey="Radbruch A">A. Radbruch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nguyen, V K" uniqKey="Nguyen V">V. K. Nguyen</name></author><author><name sortKey="Hamers, R" uniqKey="Hamers R">R. Hamers</name></author><author><name sortKey="Wyns, L" uniqKey="Wyns L">L. Wyns</name></author><author><name sortKey="Muyldermans, S" uniqKey="Muyldermans S">S. Muyldermans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ying, T" uniqKey="Ying T">T. Ying</name></author><author><name sortKey="Du, L" uniqKey="Du L">L. Du</name></author><author><name sortKey="Ju, T W" uniqKey="Ju T">T. W. Ju</name></author><author><name sortKey="Prabakaran, P" uniqKey="Prabakaran P">P. Prabakaran</name></author><author><name sortKey="Lau, C C Y" uniqKey="Lau C">C. C. Y. Lau</name></author><author><name sortKey="Lu, L" uniqKey="Lu L">L. Lu</name></author><author><name sortKey="Liu, Q" uniqKey="Liu Q">Q. Liu</name></author><author><name sortKey="Wang, L" uniqKey="Wang L">L. Wang</name></author><author><name sortKey="Feng, Y" uniqKey="Feng Y">Y. Feng</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y. Wang</name></author><author><name sortKey="Zheng, B J" uniqKey="Zheng B">B.-J. Zheng</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.-Y. Yuen</name></author><author><name sortKey="Jiang, S" uniqKey="Jiang S">S. Jiang</name></author><author><name sortKey="Dimitrov, D S" uniqKey="Dimitrov D">D. S. Dimitrov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sok, D" uniqKey="Sok D">D. Sok</name></author><author><name sortKey="Le, K M" uniqKey="Le K">K. M. Le</name></author><author><name sortKey="Vadnais, M" uniqKey="Vadnais M">M. Vadnais</name></author><author><name sortKey="Saye Francisco, K L" uniqKey="Saye Francisco K">K. L. Saye-Francisco</name></author><author><name sortKey="Jardine, J G" uniqKey="Jardine J">J. G. Jardine</name></author><author><name sortKey="Torres, J L" uniqKey="Torres J">J. L. Torres</name></author><author><name sortKey="Berndsen, Z T" uniqKey="Berndsen Z">Z. T. Berndsen</name></author><author><name sortKey="Kong, L" uniqKey="Kong L">L. Kong</name></author><author><name sortKey="Stanfield, R" uniqKey="Stanfield R">R. Stanfield</name></author><author><name sortKey="Ruiz, J" uniqKey="Ruiz J">J. Ruiz</name></author><author><name sortKey="Ramos, A" uniqKey="Ramos A">A. Ramos</name></author><author><name sortKey="Liang, C H" uniqKey="Liang C">C.-H. Liang</name></author><author><name sortKey="Chen, P L" uniqKey="Chen P">P. L. Chen</name></author><author><name sortKey="Criscitiello, M F" uniqKey="Criscitiello M">M. F. Criscitiello</name></author><author><name sortKey="Mwangi, W" uniqKey="Mwangi W">W. Mwangi</name></author><author><name sortKey="Wilson, I A" uniqKey="Wilson I">I. A. Wilson</name></author><author><name sortKey="Ward, A B" uniqKey="Ward A">A. B. Ward</name></author><author><name sortKey="Smider, V V" uniqKey="Smider V">V. V. Smider</name></author><author><name sortKey="Burton, D R" uniqKey="Burton D">D. R. Burton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sim Es, E A F" uniqKey="Sim Es E">E. A. F. Simões</name></author><author><name sortKey="Devincenzo, J P" uniqKey="Devincenzo J">J. P. DeVincenzo</name></author><author><name sortKey="Boeckh, M" uniqKey="Boeckh M">M. Boeckh</name></author><author><name sortKey="Bont, L" uniqKey="Bont L">L. Bont</name></author><author><name sortKey="Crowe, J E" uniqKey="Crowe J">J. E. Crowe</name></author><author><name sortKey="Griffiths, P" uniqKey="Griffiths P">P. Griffiths</name></author><author><name sortKey="Hayden, F G" uniqKey="Hayden F">F. G. Hayden</name></author><author><name sortKey="Hodinka, R L" uniqKey="Hodinka R">R. L. Hodinka</name></author><author><name sortKey="Smyth, R L" uniqKey="Smyth R">R. L. Smyth</name></author><author><name sortKey="Spencer, K" uniqKey="Spencer K">K. Spencer</name></author><author><name sortKey="Thirstrup, S" uniqKey="Thirstrup S">S. Thirstrup</name></author><author><name sortKey="Walsh, E E" uniqKey="Walsh E">E. E. Walsh</name></author><author><name sortKey="Whitley, R J" uniqKey="Whitley R">R. J. Whitley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Song, F" uniqKey="Song F">F. Song</name></author><author><name sortKey="Fux, R" uniqKey="Fux R">R. Fux</name></author><author><name sortKey="Provacia, L B" uniqKey="Provacia L">L. B. Provacia</name></author><author><name sortKey="Volz, A" uniqKey="Volz A">A. Volz</name></author><author><name sortKey="Eickmann, M" uniqKey="Eickmann M">M. Eickmann</name></author><author><name sortKey="Becker, S" uniqKey="Becker S">S. Becker</name></author><author><name sortKey="Osterhaus, A D M E" uniqKey="Osterhaus A">A. D. M. E. Osterhaus</name></author><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B. L. Haagmans</name></author><author><name sortKey="Sutter, G" uniqKey="Sutter G">G. Sutter</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Nakabayashi, H" uniqKey="Nakabayashi H">H. Nakabayashi</name></author><author><name sortKey="Taketa, K" uniqKey="Taketa K">K. Taketa</name></author><author><name sortKey="Miyano, K" uniqKey="Miyano K">K. Miyano</name></author><author><name sortKey="Yamane, T" uniqKey="Yamane T">T. Yamane</name></author><author><name sortKey="Sato, J" uniqKey="Sato J">J. Sato</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Boheemen, S" uniqKey="Van Boheemen S">S. van Boheemen</name></author><author><name sortKey="De Graaf, M" uniqKey="De Graaf M">M. de Graaf</name></author><author><name sortKey="Lauber, C" uniqKey="Lauber C">C. Lauber</name></author><author><name sortKey="Bestebroer, T M" uniqKey="Bestebroer T">T. M. Bestebroer</name></author><author><name sortKey="Stalin Raj, V" uniqKey="Stalin Raj V">V. Stalin Raj</name></author><author><name sortKey="Zaki, A M" uniqKey="Zaki A">A. M. Zaki</name></author><author><name sortKey="Osterhaus, A D M E" uniqKey="Osterhaus A">A. D. M. E. Osterhaus</name></author><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B. L. Haagmans</name></author><author><name sortKey="Gorbalenya, A E" uniqKey="Gorbalenya A">A. E. Gorbalenya</name></author><author><name sortKey="Snijder, E J" uniqKey="Snijder E">E. J. Snijder</name></author><author><name sortKey="Fouchier, R A M" uniqKey="Fouchier R">R. A. M. Fouchier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Smits, S L" uniqKey="Smits S">S. L. Smits</name></author><author><name sortKey="De Lang, A" uniqKey="De Lang A">A. de Lang</name></author><author><name sortKey="Van Den Brand, J M A" uniqKey="Van Den Brand J">J. M. A. van den Brand</name></author><author><name sortKey="Leijten, L M" uniqKey="Leijten L">L. M. Leijten</name></author><author><name sortKey="Van Ijcken, W F" uniqKey="Van Ijcken W">W. F. van IJcken</name></author><author><name sortKey="Eijkemans, M J C" uniqKey="Eijkemans M">M. J. C. Eijkemans</name></author><author><name sortKey="Vanamerongen, G" uniqKey="Vanamerongen G">G. vanAmerongen</name></author><author><name sortKey="Kuiken, T" uniqKey="Kuiken T">T. Kuiken</name></author><author><name sortKey="Andeweg, A C" uniqKey="Andeweg A">A. C. Andeweg</name></author><author><name sortKey="Osterhaus, A D M E" uniqKey="Osterhaus A">A. D. M. E. Osterhaus</name></author><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B. L. Haagmans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Kuppeveld, F J" uniqKey="Van Kuppeveld F">F. J. van Kuppeveld</name></author><author><name sortKey="Van Der Logt, J T" uniqKey="Van Der Logt J">J. T. van der Logt</name></author><author><name sortKey="Angulo, A F" uniqKey="Angulo A">A. F. Angulo</name></author><author><name sortKey="Van Zoest, M J" uniqKey="Van Zoest M">M. J. van Zoest</name></author><author><name sortKey="Quint, W G" uniqKey="Quint W">W. G. Quint</name></author><author><name sortKey="Niesters, H G" uniqKey="Niesters H">H. G. Niesters</name></author><author><name sortKey="Galama, J M" uniqKey="Galama J">J. M. Galama</name></author><author><name sortKey="Melchers, W J" uniqKey="Melchers W">W. J. Melchers</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B. L. Haagmans</name></author><author><name sortKey="Van Den Brand, J M A" uniqKey="Van Den Brand J">J. M. A. van den Brand</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Abdiche, Y N" uniqKey="Abdiche Y">Y. N. Abdiche</name></author><author><name sortKey="Malashock, D S" uniqKey="Malashock D">D. S. Malashock</name></author><author><name sortKey="Pinkerton, A" uniqKey="Pinkerton A">A. Pinkerton</name></author><author><name sortKey="Pons, J" uniqKey="Pons J">J. Pons</name></author></analytic></biblStruct></listBibl></div1></back></TEI><double pmid="30101189"><pmc><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection</title><author><name sortKey="Stalin Raj, V" sort="Stalin Raj, V" uniqKey="Stalin Raj V" first="V." last="Stalin Raj">V. Stalin Raj</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Okba, Nisreen M A" sort="Okba, Nisreen M A" uniqKey="Okba N" first="Nisreen M. A." last="Okba">Nisreen M. A. Okba</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Gutierrez Alvarez, Javier" sort="Gutierrez Alvarez, Javier" uniqKey="Gutierrez Alvarez J" first="Javier" last="Gutierrez-Alvarez">Javier Gutierrez-Alvarez</name><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Drabek, Dubravka" sort="Drabek, Dubravka" uniqKey="Drabek D" first="Dubravka" last="Drabek">Dubravka Drabek</name><affiliation wicri:level="3"><nlm:aff id="aff3">Department of Cell Biology, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Cell Biology, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Van Dieren, Brenda" sort="Van Dieren, Brenda" uniqKey="Van Dieren B" first="Brenda" last="Van Dieren">Brenda Van Dieren</name><affiliation wicri:level="4"><nlm:aff id="aff4">Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName><orgName type="university">Université d'Utrecht</orgName></affiliation></author><author><name sortKey="Widagdo, W" sort="Widagdo, W" uniqKey="Widagdo W" first="W." last="Widagdo">W. Widagdo</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Lamers, Mart M" sort="Lamers, Mart M" uniqKey="Lamers M" first="Mart M." last="Lamers">Mart M. Lamers</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Widjaja, Ivy" sort="Widjaja, Ivy" uniqKey="Widjaja I" first="Ivy" last="Widjaja">Ivy Widjaja</name><affiliation wicri:level="4"><nlm:aff id="aff4">Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName><orgName type="university">Université d'Utrecht</orgName></affiliation></author><author><name sortKey="Fernandez Delgado, Raul" sort="Fernandez Delgado, Raul" uniqKey="Fernandez Delgado R" first="Raul" last="Fernandez-Delgado">Raul Fernandez-Delgado</name><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Sola, Isabel" sort="Sola, Isabel" uniqKey="Sola I" first="Isabel" last="Sola">Isabel Sola</name><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Bensaid, Albert" sort="Bensaid, Albert" uniqKey="Bensaid A" first="Albert" last="Bensaid">Albert Bensaid</name><affiliation wicri:level="2"><nlm:aff id="aff5">Institut de Recerca i Tecnologia Agroalimentàries (IRTA), Centre de Recerca en Sanitat Animal [CReSA, IRTA–Universitat Autònoma de Barcelona (UAB)], Campus de la UAB, 08193 Bellaterra, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Institut de Recerca i Tecnologia Agroalimentàries (IRTA), Centre de Recerca en Sanitat Animal [CReSA, IRTA–Universitat Autònoma de Barcelona (UAB)], Campus de la UAB, 08193 Bellaterra</wicri:regionArea><placeName><region nuts="2" type="communauté">Catalogne</region></placeName></affiliation></author><author><name sortKey="Koopmans, Marion P" sort="Koopmans, Marion P" uniqKey="Koopmans M" first="Marion P." last="Koopmans">Marion P. Koopmans</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Segales, Joaquim" sort="Segales, Joaquim" uniqKey="Segales J" first="Joaquim" last="Segalés">Joaquim Segalés</name><affiliation wicri:level="2"><nlm:aff id="aff6">UAB, CReSA (IRTA-UAB), Campus de la UAB, 08193 Bellaterra, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>UAB, CReSA (IRTA-UAB), Campus de la UAB, 08193 Bellaterra</wicri:regionArea><placeName><region nuts="2" type="communauté">Catalogne</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff7">Departament de Sanitat i Anatomia Animals, Facultat de Veterinària, UAB, 08193 Bellaterra, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Departament de Sanitat i Anatomia Animals, Facultat de Veterinària, UAB, 08193 Bellaterra</wicri:regionArea><placeName><region nuts="2" type="communauté">Catalogne</region></placeName></affiliation></author><author><name sortKey="Osterhaus, Albert D M E" sort="Osterhaus, Albert D M E" uniqKey="Osterhaus A" first="Albert D. M. E." last="Osterhaus">Albert D. M. E. Osterhaus</name><affiliation wicri:level="3"><nlm:aff id="aff8">Artemis One Health, Utrecht, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Artemis One Health, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff9">Center for Infection Medicine and Zoonoses Research, University of Veterinary Medicine, Hannover, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Center for Infection Medicine and Zoonoses Research, University of Veterinary Medicine, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Bosch, Berend Jan" sort="Bosch, Berend Jan" uniqKey="Bosch B" first="Berend Jan" last="Bosch">Berend Jan Bosch</name><affiliation wicri:level="4"><nlm:aff id="aff4">Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName><orgName type="university">Université d'Utrecht</orgName></affiliation></author><author><name sortKey="Enjuanes, Luis" sort="Enjuanes, Luis" uniqKey="Enjuanes L" first="Luis" last="Enjuanes">Luis Enjuanes</name><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Haagmans, Bart L" sort="Haagmans, Bart L" uniqKey="Haagmans B" first="Bart L." last="Haagmans">Bart L. Haagmans</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">30101189</idno><idno type="pmc">6082650</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082650</idno><idno type="RBID">PMC:6082650</idno><idno type="doi">10.1126/sciadv.aas9667</idno><date when="2018">2018</date><idno type="wicri:Area/Pmc/Corpus">001141</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001141</idno><idno type="wicri:Area/Pmc/Curation">001141</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001141</idno><idno type="wicri:Area/Pmc/Checkpoint">000625</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000625</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection</title><author><name sortKey="Stalin Raj, V" sort="Stalin Raj, V" uniqKey="Stalin Raj V" first="V." last="Stalin Raj">V. Stalin Raj</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Okba, Nisreen M A" sort="Okba, Nisreen M A" uniqKey="Okba N" first="Nisreen M. A." last="Okba">Nisreen M. A. Okba</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Gutierrez Alvarez, Javier" sort="Gutierrez Alvarez, Javier" uniqKey="Gutierrez Alvarez J" first="Javier" last="Gutierrez-Alvarez">Javier Gutierrez-Alvarez</name><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Drabek, Dubravka" sort="Drabek, Dubravka" uniqKey="Drabek D" first="Dubravka" last="Drabek">Dubravka Drabek</name><affiliation wicri:level="3"><nlm:aff id="aff3">Department of Cell Biology, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Cell Biology, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Van Dieren, Brenda" sort="Van Dieren, Brenda" uniqKey="Van Dieren B" first="Brenda" last="Van Dieren">Brenda Van Dieren</name><affiliation wicri:level="4"><nlm:aff id="aff4">Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName><orgName type="university">Université d'Utrecht</orgName></affiliation></author><author><name sortKey="Widagdo, W" sort="Widagdo, W" uniqKey="Widagdo W" first="W." last="Widagdo">W. Widagdo</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Lamers, Mart M" sort="Lamers, Mart M" uniqKey="Lamers M" first="Mart M." last="Lamers">Mart M. Lamers</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Widjaja, Ivy" sort="Widjaja, Ivy" uniqKey="Widjaja I" first="Ivy" last="Widjaja">Ivy Widjaja</name><affiliation wicri:level="4"><nlm:aff id="aff4">Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName><orgName type="university">Université d'Utrecht</orgName></affiliation></author><author><name sortKey="Fernandez Delgado, Raul" sort="Fernandez Delgado, Raul" uniqKey="Fernandez Delgado R" first="Raul" last="Fernandez-Delgado">Raul Fernandez-Delgado</name><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Sola, Isabel" sort="Sola, Isabel" uniqKey="Sola I" first="Isabel" last="Sola">Isabel Sola</name><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Bensaid, Albert" sort="Bensaid, Albert" uniqKey="Bensaid A" first="Albert" last="Bensaid">Albert Bensaid</name><affiliation wicri:level="2"><nlm:aff id="aff5">Institut de Recerca i Tecnologia Agroalimentàries (IRTA), Centre de Recerca en Sanitat Animal [CReSA, IRTA–Universitat Autònoma de Barcelona (UAB)], Campus de la UAB, 08193 Bellaterra, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Institut de Recerca i Tecnologia Agroalimentàries (IRTA), Centre de Recerca en Sanitat Animal [CReSA, IRTA–Universitat Autònoma de Barcelona (UAB)], Campus de la UAB, 08193 Bellaterra</wicri:regionArea><placeName><region nuts="2" type="communauté">Catalogne</region></placeName></affiliation></author><author><name sortKey="Koopmans, Marion P" sort="Koopmans, Marion P" uniqKey="Koopmans M" first="Marion P." last="Koopmans">Marion P. Koopmans</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Segales, Joaquim" sort="Segales, Joaquim" uniqKey="Segales J" first="Joaquim" last="Segalés">Joaquim Segalés</name><affiliation wicri:level="2"><nlm:aff id="aff6">UAB, CReSA (IRTA-UAB), Campus de la UAB, 08193 Bellaterra, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>UAB, CReSA (IRTA-UAB), Campus de la UAB, 08193 Bellaterra</wicri:regionArea><placeName><region nuts="2" type="communauté">Catalogne</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff7">Departament de Sanitat i Anatomia Animals, Facultat de Veterinària, UAB, 08193 Bellaterra, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Departament de Sanitat i Anatomia Animals, Facultat de Veterinària, UAB, 08193 Bellaterra</wicri:regionArea><placeName><region nuts="2" type="communauté">Catalogne</region></placeName></affiliation></author><author><name sortKey="Osterhaus, Albert D M E" sort="Osterhaus, Albert D M E" uniqKey="Osterhaus A" first="Albert D. M. E." last="Osterhaus">Albert D. M. E. Osterhaus</name><affiliation wicri:level="3"><nlm:aff id="aff8">Artemis One Health, Utrecht, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Artemis One Health, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff9">Center for Infection Medicine and Zoonoses Research, University of Veterinary Medicine, Hannover, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Center for Infection Medicine and Zoonoses Research, University of Veterinary Medicine, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Bosch, Berend Jan" sort="Bosch, Berend Jan" uniqKey="Bosch B" first="Berend Jan" last="Bosch">Berend Jan Bosch</name><affiliation wicri:level="4"><nlm:aff id="aff4">Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName><orgName type="university">Université d'Utrecht</orgName></affiliation></author><author><name sortKey="Enjuanes, Luis" sort="Enjuanes, Luis" uniqKey="Enjuanes L" first="Luis" last="Enjuanes">Luis Enjuanes</name><affiliation wicri:level="3"><nlm:aff id="aff2">Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology–Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Haagmans, Bart L" sort="Haagmans, Bart L" uniqKey="Haagmans B" first="Bart L." last="Haagmans">Bart L. Haagmans</name><affiliation wicri:level="3"><nlm:aff id="aff1">Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author></analytic><series><title level="j">Science Advances</title><idno type="eISSN">2375-2548</idno><imprint><date when="2018">2018</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Dromedary camel heavy chain–only antibodies may provide novel intervention strategies against MERS coronavirus.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Zaki, A M" uniqKey="Zaki A">A. M. Zaki</name></author><author><name sortKey="Van Boheemen, S" uniqKey="Van Boheemen S">S. van Boheemen</name></author><author><name sortKey="Bestebroer, T M" uniqKey="Bestebroer T">T. M. Bestebroer</name></author><author><name sortKey="Osterhaus, A D M E" uniqKey="Osterhaus A">A. D. M. E. Osterhaus</name></author><author><name sortKey="Fouchier, R A M" uniqKey="Fouchier R">R. A. M. Fouchier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cauchemez, S" uniqKey="Cauchemez S">S. Cauchemez</name></author><author><name sortKey="Nouvellet, P" uniqKey="Nouvellet P">P. Nouvellet</name></author><author><name sortKey="Cori, A" uniqKey="Cori A">A. Cori</name></author><author><name sortKey="Jombart, T" uniqKey="Jombart T">T. Jombart</name></author><author><name sortKey="Garske, T" uniqKey="Garske T">T. Garske</name></author><author><name sortKey="Clapham, H" uniqKey="Clapham H">H. Clapham</name></author><author><name sortKey="Moore, S" uniqKey="Moore S">S. Moore</name></author><author><name sortKey="Mills, H L" uniqKey="Mills H">H. L. Mills</name></author><author><name sortKey="Salje, H" uniqKey="Salje H">H. Salje</name></author><author><name sortKey="Collins, C" uniqKey="Collins C">C. Collins</name></author><author><name sortKey="Rodriquez Barraquer, I" uniqKey="Rodriquez Barraquer I">I. Rodriquez-Barraquer</name></author><author><name sortKey="Riley, S" uniqKey="Riley S">S. Riley</name></author><author><name sortKey="Truelove, S" uniqKey="Truelove S">S. Truelove</name></author><author><name sortKey="Algarni, H" uniqKey="Algarni H">H. Algarni</name></author><author><name sortKey="Alhakeem, R" uniqKey="Alhakeem R">R. Alhakeem</name></author><author><name sortKey="Alharbi, K" uniqKey="Alharbi K">K. AlHarbi</name></author><author><name sortKey="Turkistani, A" uniqKey="Turkistani A">A. Turkistani</name></author><author><name sortKey="Aguas, R J" uniqKey="Aguas R">R. J. Aguas</name></author><author><name sortKey="Cummings, D A T" uniqKey="Cummings D">D. A. T. Cummings</name></author><author><name sortKey="Van Kerkhove, M D" uniqKey="Van Kerkhove M">M. D. Van Kerkhove</name></author><author><name sortKey="Donnelly, C A" uniqKey="Donnelly C">C. A. Donnelly</name></author><author><name sortKey="Lessler, J" uniqKey="Lessler J">J. Lessler</name></author><author><name sortKey="Fraser, C" uniqKey="Fraser C">C. Fraser</name></author><author><name sortKey="Al Barrak, A" uniqKey="Al Barrak A">A. Al-Barrak</name></author><author><name sortKey="Ferguson, N M" uniqKey="Ferguson N">N. M. Ferguson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Raj, V S" uniqKey="Raj V">V. S. Raj</name></author><author><name sortKey="Farag, E A B A" uniqKey="Farag E">E. A. B. A. Farag</name></author><author><name sortKey="Reusken, C B E M" uniqKey="Reusken C">C. B. E. M. Reusken</name></author><author><name sortKey="Lamers, M M" uniqKey="Lamers M">M. M. Lamers</name></author><author><name sortKey="Pas, S D" uniqKey="Pas S">S. D. Pas</name></author><author><name sortKey="Voermans, J" uniqKey="Voermans J">J. Voermans</name></author><author><name sortKey="Smits, S L" uniqKey="Smits S">S. L. Smits</name></author><author><name sortKey="Osterhaus, A D M E" uniqKey="Osterhaus A">A. D. M. E. Osterhaus</name></author><author><name sortKey="Al Mawlawi, N" uniqKey="Al Mawlawi N">N. Al-Mawlawi</name></author><author><name sortKey="Al Romaihi, H E" uniqKey="Al Romaihi H">H. E. Al-Romaihi</name></author><author><name sortKey="Alhajri, M M" uniqKey="Alhajri M">M. M. AlHajri</name></author><author><name sortKey="El Sayed, A M" uniqKey="El Sayed A">A. M. El-Sayed</name></author><author><name sortKey="Mohran, K A" uniqKey="Mohran K">K. A. Mohran</name></author><author><name sortKey="Ghobashy, H" uniqKey="Ghobashy H">H. Ghobashy</name></author><author><name sortKey="Alhajri, F" uniqKey="Alhajri F">F. Alhajri</name></author><author><name sortKey="Al Thani, M" uniqKey="Al Thani M">M. Al-Thani</name></author><author><name sortKey="Al Marri, S A" uniqKey="Al Marri S">S. A. Al-Marri</name></author><author><name sortKey="El Maghraby, M M" uniqKey="El Maghraby M">M. M. El-Maghraby</name></author><author><name sortKey="Koopmans, M P G" uniqKey="Koopmans M">M. P. G. Koopmans</name></author><author><name sortKey="Haagmans, Bart L" uniqKey="Haagmans B">Bart L. Haagmans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cotten, M" uniqKey="Cotten M">M. Cotten</name></author><author><name sortKey="Watson, S J" uniqKey="Watson S">S. J. Watson</name></author><author><name sortKey="Kellam, P" uniqKey="Kellam P">P. Kellam</name></author><author><name sortKey="Al Rabeeah, A A" uniqKey="Al Rabeeah A">A. A. Al-Rabeeah</name></author><author><name sortKey="Makhdoom, H Q" uniqKey="Makhdoom H">H. Q. Makhdoom</name></author><author><name sortKey="Assiri, A" uniqKey="Assiri A">A. Assiri</name></author><author><name sortKey="Al Tawfiq, J A" uniqKey="Al Tawfiq J">J. A. Al-Tawfiq</name></author><author><name sortKey="Alhakeem, R F" uniqKey="Alhakeem R">R. F. Alhakeem</name></author><author><name sortKey="Madani, H" uniqKey="Madani H">H. Madani</name></author><author><name sortKey="Alrabiah, F A" uniqKey="Alrabiah F">F. A. AlRabiah</name></author><author><name sortKey="Hajjar, S A" uniqKey="Hajjar S">S. A. Hajjar</name></author><author><name sortKey="Al Nassir, W N" uniqKey="Al Nassir W">W. N. Al-nassir</name></author><author><name sortKey="Albarrak, A" uniqKey="Albarrak A">A. Albarrak</name></author><author><name sortKey="Flemban, H" uniqKey="Flemban H">H. Flemban</name></author><author><name sortKey="Balkhy, H H" uniqKey="Balkhy H">H. H. Balkhy</name></author><author><name sortKey="Alsubaie, S" uniqKey="Alsubaie S">S. Alsubaie</name></author><author><name sortKey="Palser, A L" uniqKey="Palser A">A. L. Palser</name></author><author><name sortKey="Gall, A" uniqKey="Gall A">A. Gall</name></author><author><name sortKey="Memish, Z A" uniqKey="Memish Z">Z. A. Memish</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tang, X C" uniqKey="Tang X">X.-C. Tang</name></author><author><name sortKey="Agnihothram, S S" uniqKey="Agnihothram S">S. S. Agnihothram</name></author><author><name sortKey="Jiao, Y" uniqKey="Jiao Y">Y. Jiao</name></author><author><name sortKey="Stanhope, J" uniqKey="Stanhope J">J. Stanhope</name></author><author><name sortKey="Graham, R L" uniqKey="Graham R">R. L. Graham</name></author><author><name sortKey="Peterson, E C" uniqKey="Peterson E">E. C. Peterson</name></author><author><name sortKey="Avnir, Y" uniqKey="Avnir Y">Y. Avnir</name></author><author><name sortKey="St Clair Tallarico, A" uniqKey="St Clair Tallarico A">A. St. Clair Tallarico</name></author><author><name sortKey="Sheehan, J" uniqKey="Sheehan J">J. Sheehan</name></author><author><name sortKey="Zhu, Q" uniqKey="Zhu Q">Q. Zhu</name></author><author><name sortKey="Baric, R S" uniqKey="Baric R">R. S. Baric</name></author><author><name sortKey="Marasco, W A" uniqKey="Marasco W">W. A. Marasco</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Corti, D" uniqKey="Corti D">D. Corti</name></author><author><name sortKey="Zhao, J" uniqKey="Zhao J">J. Zhao</name></author><author><name sortKey="Pedotti, M" uniqKey="Pedotti M">M. Pedotti</name></author><author><name sortKey="Simonelli, L" uniqKey="Simonelli L">L. Simonelli</name></author><author><name sortKey="Agnihothram, S" uniqKey="Agnihothram S">S. Agnihothram</name></author><author><name sortKey="Fett, C" uniqKey="Fett C">C. Fett</name></author><author><name sortKey="Fernandez Rodriguez, B" uniqKey="Fernandez Rodriguez B">B. Fernandez-Rodriguez</name></author><author><name sortKey="Foglierini, M" uniqKey="Foglierini M">M. Foglierini</name></author><author><name sortKey="Agatic, G" uniqKey="Agatic G">G. Agatic</name></author><author><name sortKey="Vanzetta, F" uniqKey="Vanzetta F">F. Vanzetta</name></author><author><name sortKey="Gopal, R" uniqKey="Gopal R">R. Gopal</name></author><author><name sortKey="Langrish, C J" uniqKey="Langrish C">C. J. Langrish</name></author><author><name sortKey="Barrett, N A" uniqKey="Barrett N">N. A. Barrett</name></author><author><name sortKey="Sallusto, F" uniqKey="Sallusto F">F. Sallusto</name></author><author><name sortKey="Baric, R S" uniqKey="Baric R">R. S. Baric</name></author><author><name sortKey="Varani, L" uniqKey="Varani L">L. Varani</name></author><author><name sortKey="Zambon, M" uniqKey="Zambon M">M. Zambon</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S. Perlman</name></author><author><name sortKey="Lanzavecchia, A" uniqKey="Lanzavecchia A">A. Lanzavecchia</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pascal, K E" uniqKey="Pascal K">K. E. Pascal</name></author><author><name sortKey="Coleman, C M" uniqKey="Coleman C">C. M. Coleman</name></author><author><name sortKey="Mujica, A O" uniqKey="Mujica A">A. O. Mujica</name></author><author><name sortKey="Kamat, V" uniqKey="Kamat V">V. Kamat</name></author><author><name sortKey="Badithe, A" uniqKey="Badithe A">A. Badithe</name></author><author><name sortKey="Fairhurst, J" uniqKey="Fairhurst J">J. Fairhurst</name></author><author><name sortKey="Hunt, C" uniqKey="Hunt C">C. Hunt</name></author><author><name sortKey="Strein, J" uniqKey="Strein J">J. Strein</name></author><author><name sortKey="Berrebi, A" uniqKey="Berrebi A">A. Berrebi</name></author><author><name sortKey="Sisk, J M" uniqKey="Sisk J">J. M. Sisk</name></author><author><name sortKey="Matthews, K L" uniqKey="Matthews K">K. L. Matthews</name></author><author><name sortKey="Babb, R" uniqKey="Babb R">R. Babb</name></author><author><name sortKey="Chen, G" uniqKey="Chen G">G. Chen</name></author><author><name sortKey="Lai, K M V" uniqKey="Lai K">K.-M. V. Lai</name></author><author><name sortKey="Huang, T T" uniqKey="Huang T">T. T. Huang</name></author><author><name sortKey="Olson, W" uniqKey="Olson W">W. Olson</name></author><author><name sortKey="Yancopoulos, G D" uniqKey="Yancopoulos G">G. D. Yancopoulos</name></author><author><name sortKey="Stahl, N" uniqKey="Stahl N">N. Stahl</name></author><author><name sortKey="Frieman, M B" uniqKey="Frieman M">M. B. Frieman</name></author><author><name sortKey="Kyratsous, C A" uniqKey="Kyratsous C">C. A. Kyratsous</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Raj, V S" uniqKey="Raj V">V. S. Raj</name></author><author><name sortKey="Mou, H" uniqKey="Mou H">H. Mou</name></author><author><name sortKey="Smits, S L" uniqKey="Smits S">S. L. Smits</name></author><author><name sortKey="Dekkers, D H W" uniqKey="Dekkers D">D. H. W. Dekkers</name></author><author><name sortKey="Muller, M A" uniqKey="Muller M">M. A. Müller</name></author><author><name sortKey="Dijkman, R" uniqKey="Dijkman R">R. Dijkman</name></author><author><name sortKey="Muth, D" uniqKey="Muth D">D. Muth</name></author><author><name sortKey="Demmers, J A A" uniqKey="Demmers J">J. A. A. Demmers</name></author><author><name sortKey="Zaki, A" uniqKey="Zaki A">A. Zaki</name></author><author><name sortKey="Fouchier, R A M" uniqKey="Fouchier R">R. A. M. Fouchier</name></author><author><name sortKey="Thiel, V" uniqKey="Thiel V">V. Thiel</name></author><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author><author><name sortKey="Rottier, P J M" uniqKey="Rottier P">P. J. M. Rottier</name></author><author><name sortKey="Osterhaus, A D M E" uniqKey="Osterhaus A">A. D. M. E. Osterhaus</name></author><author><name sortKey="Bosch, B J" uniqKey="Bosch B">B. J. Bosch</name></author><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B. L. Haagmans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mou, H" uniqKey="Mou H">H. Mou</name></author><author><name sortKey="Raj, V S" uniqKey="Raj V">V. S. Raj</name></author><author><name sortKey="Van Kuppeveld, F J M" uniqKey="Van Kuppeveld F">F. J. M. van Kuppeveld</name></author><author><name sortKey="Rottier, P J M" uniqKey="Rottier P">P. J. M. Rottier</name></author><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B. L. Haagmans</name></author><author><name sortKey="Bosch, B J" uniqKey="Bosch B">B. J. Bosch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Al Amri, S S" uniqKey="Al Amri S">S. S. Al-amri</name></author><author><name sortKey="Abbas, A T" uniqKey="Abbas A">A. T. Abbas</name></author><author><name sortKey="Siddiq, L A" uniqKey="Siddiq L">L. A. Siddiq</name></author><author><name sortKey="Alghamdi, A" uniqKey="Alghamdi A">A. Alghamdi</name></author><author><name sortKey="Sanki, M A" uniqKey="Sanki M">M. A. Sanki</name></author><author><name sortKey="Al Muhanna, M K" uniqKey="Al Muhanna M">M. K. Al-Muhanna</name></author><author><name sortKey="Alhabbab, R Y" uniqKey="Alhabbab R">R. Y. Alhabbab</name></author><author><name sortKey="Azhar, E I" uniqKey="Azhar E">E. I. Azhar</name></author><author><name sortKey="Li, X" uniqKey="Li X">X. Li</name></author><author><name sortKey="Hashem, A M" uniqKey="Hashem A">A. M. Hashem</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, Y" uniqKey="Li Y">Y. Li</name></author><author><name sortKey="Wan, Y" uniqKey="Wan Y">Y. Wan</name></author><author><name sortKey="Liu, P" uniqKey="Liu P">P. Liu</name></author><author><name sortKey="Zhao, J" uniqKey="Zhao J">J. Zhao</name></author><author><name sortKey="Lu, G" uniqKey="Lu G">G. Lu</name></author><author><name sortKey="Qi, J" uniqKey="Qi J">J. Qi</name></author><author><name sortKey="Wang, Q" uniqKey="Wang Q">Q. Wang</name></author><author><name sortKey="Lu, X" uniqKey="Lu X">X. Lu</name></author><author><name sortKey="Wu, Y" uniqKey="Wu Y">Y. Wu</name></author><author><name sortKey="Liu, W" uniqKey="Liu W">W. Liu</name></author><author><name sortKey="Zhang, B" uniqKey="Zhang B">B. Zhang</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.-Y. Yuen</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S. Perlman</name></author><author><name sortKey="Gao, G F" uniqKey="Gao G">G. F. Gao</name></author><author><name sortKey="Yan, J" uniqKey="Yan J">J. Yan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jiang, L" uniqKey="Jiang L">L. Jiang</name></author><author><name sortKey="Wang, N" uniqKey="Wang N">N. Wang</name></author><author><name sortKey="Zuo, T" uniqKey="Zuo T">T. Zuo</name></author><author><name sortKey="Shi, X" uniqKey="Shi X">X. Shi</name></author><author><name sortKey="Poon, K M V" uniqKey="Poon K">K.-M. V. Poon</name></author><author><name sortKey="Wu, Y" uniqKey="Wu Y">Y. Wu</name></author><author><name sortKey="Gao, F" uniqKey="Gao F">F. Gao</name></author><author><name sortKey="Li, D" uniqKey="Li D">D. Li</name></author><author><name sortKey="Wang, R" uniqKey="Wang R">R. Wang</name></author><author><name sortKey="Guo, J" uniqKey="Guo J">J. Guo</name></author><author><name sortKey="Fu, L" uniqKey="Fu L">L. Fu</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.-Y. Yuen</name></author><author><name sortKey="Zheng, B J" uniqKey="Zheng B">B.-J. Zheng</name></author><author><name sortKey="Wang, X" uniqKey="Wang X">X. Wang</name></author><author><name sortKey="Zhang, L" uniqKey="Zhang L">L. Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Agrawal, A S" uniqKey="Agrawal A">A. S. Agrawal</name></author><author><name sortKey="Ying, T" uniqKey="Ying T">T. Ying</name></author><author><name sortKey="Tao, X" uniqKey="Tao X">X. Tao</name></author><author><name sortKey="Garron, T" uniqKey="Garron T">T. Garron</name></author><author><name sortKey="Algaissi, A" uniqKey="Algaissi A">A. Algaissi</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y. Wang</name></author><author><name sortKey="Wang, L" uniqKey="Wang L">L. Wang</name></author><author><name sortKey="Peng, B H" uniqKey="Peng B">B.-H. Peng</name></author><author><name sortKey="Jiang, S" uniqKey="Jiang S">S. Jiang</name></author><author><name sortKey="Dimitrov, D S" uniqKey="Dimitrov D">D. S. Dimitrov</name></author><author><name sortKey="Tseng, C T K" uniqKey="Tseng C">C.-T. K. Tseng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yu, X" uniqKey="Yu X">X. Yu</name></author><author><name sortKey="Zhang, S" uniqKey="Zhang S">S. Zhang</name></author><author><name sortKey="Jiang, L" uniqKey="Jiang L">L. Jiang</name></author><author><name sortKey="Cui, Y" uniqKey="Cui Y">Y. Cui</name></author><author><name sortKey="Li, D" uniqKey="Li D">D. Li</name></author><author><name sortKey="Wang, D" uniqKey="Wang D">D. Wang</name></author><author><name sortKey="Wang, N" uniqKey="Wang N">N. Wang</name></author><author><name sortKey="Fu, L" uniqKey="Fu L">L. Fu</name></author><author><name sortKey="Shi, X" uniqKey="Shi X">X. Shi</name></author><author><name sortKey="Li, Z" uniqKey="Li Z">Z. Li</name></author><author><name sortKey="Zhang, L" uniqKey="Zhang L">L. Zhang</name></author><author><name sortKey="Wang, X" uniqKey="Wang X">X. Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chames, P" uniqKey="Chames P">P. Chames</name></author><author><name sortKey="Van Regenmortel, M" uniqKey="Van Regenmortel M">M. Van Regenmortel</name></author><author><name sortKey="Weiss, E" uniqKey="Weiss E">E. Weiss</name></author><author><name sortKey="Baty, D" uniqKey="Baty D">D. Baty</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Spadiut, O" uniqKey="Spadiut O">O. Spadiut</name></author><author><name sortKey="Capone, S" uniqKey="Capone S">S. Capone</name></author><author><name sortKey="Krainer, F" uniqKey="Krainer F">F. Krainer</name></author><author><name sortKey="Glieder, A" uniqKey="Glieder A">A. Glieder</name></author><author><name sortKey="Herwig, C" uniqKey="Herwig C">C. Herwig</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Irani, V" uniqKey="Irani V">V. Irani</name></author><author><name sortKey="Guy, A J" uniqKey="Guy A">A. J. Guy</name></author><author><name sortKey="Andrew, D" uniqKey="Andrew D">D. Andrew</name></author><author><name sortKey="Beeson, J G" uniqKey="Beeson J">J. G. Beeson</name></author><author><name sortKey="Ramsland, P A" uniqKey="Ramsland P">P. A. Ramsland</name></author><author><name sortKey="Richards, J S" uniqKey="Richards J">J. S. Richards</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hamers Casterman, C" uniqKey="Hamers Casterman C">C. Hamers-Casterman</name></author><author><name sortKey="Atarhouch, T" uniqKey="Atarhouch T">T. Atarhouch</name></author><author><name sortKey="Muyldermans, S" uniqKey="Muyldermans S">S. Muyldermans</name></author><author><name sortKey="Robinson, G" uniqKey="Robinson G">G. Robinson</name></author><author><name sortKey="Hammers, C" uniqKey="Hammers C">C. Hammers</name></author><author><name sortKey="Songa, E B" uniqKey="Songa E">E. B. Songa</name></author><author><name sortKey="Bendahman, N" uniqKey="Bendahman N">N. Bendahman</name></author><author><name sortKey="Hammers, R" uniqKey="Hammers R">R. Hammers</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Muyldermans, S" uniqKey="Muyldermans S">S. Muyldermans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Genst, E" uniqKey="De Genst E">E. De Genst</name></author><author><name sortKey="Silence, K" uniqKey="Silence K">K. Silence</name></author><author><name sortKey="Decanniere, K" uniqKey="Decanniere K">K. Decanniere</name></author><author><name sortKey="Conrath, K" uniqKey="Conrath K">K. Conrath</name></author><author><name sortKey="Loris, R" uniqKey="Loris R">R. Loris</name></author><author><name sortKey="Kinne, J" uniqKey="Kinne J">J. Kinne</name></author><author><name sortKey="Muyldermans, S" uniqKey="Muyldermans S">S. Muyldermans</name></author><author><name sortKey="Wyns, L" uniqKey="Wyns L">L. Wyns</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rothbauer, U" uniqKey="Rothbauer U">U. Rothbauer</name></author><author><name sortKey="Zolghadr, K" uniqKey="Zolghadr K">K. Zolghadr</name></author><author><name sortKey="Tillib, S" uniqKey="Tillib S">S. Tillib</name></author><author><name sortKey="Nowak, D" uniqKey="Nowak D">D. Nowak</name></author><author><name sortKey="Schermelleh, L" uniqKey="Schermelleh L">L. Schermelleh</name></author><author><name sortKey="Gahl, A" uniqKey="Gahl A">A. Gahl</name></author><author><name sortKey="Backmann, N" uniqKey="Backmann N">N. Backmann</name></author><author><name sortKey="Conrath, K" uniqKey="Conrath K">K. Conrath</name></author><author><name sortKey="Muyldermans, S" uniqKey="Muyldermans S">S. Muyldermans</name></author><author><name sortKey="Cardoso, M C" uniqKey="Cardoso M">M. C. Cardoso</name></author><author><name sortKey="Leonhardt, H" uniqKey="Leonhardt H">H. Leonhardt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hassanzadeh Ghassabeh, G" uniqKey="Hassanzadeh Ghassabeh G">G. Hassanzadeh-Ghassabeh</name></author><author><name sortKey="Devoogdt, N" uniqKey="Devoogdt N">N. Devoogdt</name></author><author><name sortKey="De Pauw, P" uniqKey="De Pauw P">P. De Pauw</name></author><author><name sortKey="Vincke, C" uniqKey="Vincke C">C. Vincke</name></author><author><name sortKey="Muyldermans, S" uniqKey="Muyldermans S">S. Muyldermans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Peyvandi, F" uniqKey="Peyvandi F">F. Peyvandi</name></author><author><name sortKey="Scully, M" uniqKey="Scully M">M. Scully</name></author><author><name sortKey="Kremer Hovinga, J A" uniqKey="Kremer Hovinga J">J. A. Kremer Hovinga</name></author><author><name sortKey="Cataland, S" uniqKey="Cataland S">S. Cataland</name></author><author><name sortKey="Knobl, P" uniqKey="Knobl P">P. Knöbl</name></author><author><name sortKey="Wu, H" uniqKey="Wu H">H. Wu</name></author><author><name sortKey="Artoni, A" uniqKey="Artoni A">A. Artoni</name></author><author><name sortKey="Westwood, J P" uniqKey="Westwood J">J. P. Westwood</name></author><author><name sortKey="Mansouri Taleghani, M" uniqKey="Mansouri Taleghani M">M. Mansouri Taleghani</name></author><author><name sortKey="Jilma, B" uniqKey="Jilma B">B. Jilma</name></author><author><name sortKey="Callewaert, F" uniqKey="Callewaert F">F. Callewaert</name></author><author><name sortKey="Ulrichts, H" uniqKey="Ulrichts H">H. Ulrichts</name></author><author><name sortKey="Duby, C" uniqKey="Duby C">C. Duby</name></author><author><name sortKey="Tersago, D" uniqKey="Tersago D">D. Tersago</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vanlandschoot, P" uniqKey="Vanlandschoot P">P. Vanlandschoot</name></author><author><name sortKey="Stortelers, C" uniqKey="Stortelers C">C. Stortelers</name></author><author><name sortKey="Beirnaert, E" uniqKey="Beirnaert E">E. Beirnaert</name></author><author><name sortKey="Iba Ez, L I" uniqKey="Iba Ez L">L. I. Ibañez</name></author><author><name sortKey="Schepens, B" uniqKey="Schepens B">B. Schepens</name></author><author><name sortKey="Depla, E" uniqKey="Depla E">E. Depla</name></author><author><name sortKey="Saelens, X" uniqKey="Saelens X">X. Saelens</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Farag, E A B A" uniqKey="Farag E">E. A. B. A. Farag</name></author><author><name sortKey="Reusken, C B E M" uniqKey="Reusken C">C. B. E. M. Reusken</name></author><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B. L. Haagmans</name></author><author><name sortKey="Mohran, K A" uniqKey="Mohran K">K. A. Mohran</name></author><author><name sortKey="Stalin Raj, V" uniqKey="Stalin Raj V">V. Stalin Raj</name></author><author><name sortKey="Pas, S D" uniqKey="Pas S">S. D. Pas</name></author><author><name sortKey="Voermans, J" uniqKey="Voermans J">J. Voermans</name></author><author><name sortKey="Smits, S L" uniqKey="Smits S">S. L. Smits</name></author><author><name sortKey="Godeke, G J" uniqKey="Godeke G">G.-J. Godeke</name></author><author><name sortKey="Al Hajri, M M" uniqKey="Al Hajri M">M. M. Al-Hajri</name></author><author><name sortKey="Alhajri, F H" uniqKey="Alhajri F">F. H. Alhajri</name></author><author><name sortKey="Al Romaihi, H E" uniqKey="Al Romaihi H">H. E. Al-Romaihi</name></author><author><name sortKey="Ghobashy, H" uniqKey="Ghobashy H">H. Ghobashy</name></author><author><name sortKey="El Maghraby, M M" uniqKey="El Maghraby M">M. M. El-Maghraby</name></author><author><name sortKey="El Sayed, A M" uniqKey="El Sayed A">A. M. El-Sayed</name></author><author><name sortKey="Al Thani, M H J" uniqKey="Al Thani M">M. H. J. Al Thani</name></author><author><name sortKey="Al Marri, S" uniqKey="Al Marri S">S. Al-Marri</name></author><author><name sortKey="Koopmans, M P G" uniqKey="Koopmans M">M. P. G. Koopmans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Reusken, C B E M" uniqKey="Reusken C">C. B. E. M. Reusken</name></author><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B. L. Haagmans</name></author><author><name sortKey="Muller, M A" uniqKey="Muller M">M. A. Müller</name></author><author><name sortKey="Gutierrez, C" uniqKey="Gutierrez C">C. Gutierrez</name></author><author><name sortKey="Godeke, G J" uniqKey="Godeke G">G.-J. Godeke</name></author><author><name sortKey="Meyer, B" uniqKey="Meyer B">B. Meyer</name></author><author><name sortKey="Muth, D" uniqKey="Muth D">D. Muth</name></author><author><name sortKey="Stalin Raj, V" uniqKey="Stalin Raj V">V. Stalin Raj</name></author><author><name sortKey="Smits De Vries, L" uniqKey="Smits De Vries L">L. Smits-De Vries</name></author><author><name sortKey="Corman, V M" uniqKey="Corman V">V. M. Corman</name></author><author><name sortKey="Drexler, J F" uniqKey="Drexler J">J.-F. Drexler</name></author><author><name sortKey="Smits, S L" uniqKey="Smits S">S. L. Smits</name></author><author><name sortKey="El Tahir, Y E" uniqKey="El Tahir Y">Y. E. El Tahir</name></author><author><name sortKey="De Sousa, R" uniqKey="De Sousa R">R. De Sousa</name></author><author><name sortKey="Van Beek, J" uniqKey="Van Beek J">J. van Beek</name></author><author><name sortKey="Nowotny, N" uniqKey="Nowotny N">N. Nowotny</name></author><author><name sortKey="Van Maanen, K" uniqKey="Van Maanen K">K. van Maanen</name></author><author><name sortKey="Hidalgo Hermoso, E" uniqKey="Hidalgo Hermoso E">E. Hidalgo-Hermoso</name></author><author><name sortKey="Koopmans, M P G" uniqKey="Koopmans M">M. P. G. Koopmans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Muller, M A" uniqKey="Muller M">M. A. Müller</name></author><author><name sortKey="Corman, V M" uniqKey="Corman V">V. M. Corman</name></author><author><name sortKey="Jores, J" uniqKey="Jores J">J. Jores</name></author><author><name sortKey="Meyer, B" uniqKey="Meyer B">B. Meyer</name></author><author><name sortKey="Younan, M" uniqKey="Younan M">M. Younan</name></author><author><name sortKey="Liljander, A M" uniqKey="Liljander A">A. M. Liljander</name></author><author><name sortKey="Bosch, B J" uniqKey="Bosch B">B.-J. Bosch</name></author><author><name sortKey="Lattwein, E" uniqKey="Lattwein E">E. Lattwein</name></author><author><name sortKey="Hilali, M" uniqKey="Hilali M">M. Hilali</name></author><author><name sortKey="Musa, B E" uniqKey="Musa B">B. E. Musa</name></author><author><name sortKey="Bornstein, S" uniqKey="Bornstein S">S. Bornstein</name></author><author><name sortKey="Park, S S" uniqKey="Park S">S. S. Park</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B. L. Haagmans</name></author><author><name sortKey="Van Den Brand, J M A" uniqKey="Van Den Brand J">J. M. A. van den Brand,</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pardon, E" uniqKey="Pardon E">E. Pardon</name></author><author><name sortKey="Laeremans, T" uniqKey="Laeremans T">T. Laeremans</name></author><author><name sortKey="Triest, S" uniqKey="Triest S">S. Triest</name></author><author><name sortKey="Rasmussen, S G F" uniqKey="Rasmussen S">S. G. F. Rasmussen</name></author><author><name sortKey="Wohlkonig, A" uniqKey="Wohlkonig A">A. Wohlkönig</name></author><author><name sortKey="Ruf, A" uniqKey="Ruf A">A. Ruf</name></author><author><name sortKey="Muyldermans, S" uniqKey="Muyldermans S">S. Muyldermans</name></author><author><name sortKey="Hol, W G J" uniqKey="Hol W">W. G. J. Hol</name></author><author><name sortKey="Kobilka, B K" uniqKey="Kobilka B">B. K. Kobilka</name></author><author><name sortKey="Steyaert, J" uniqKey="Steyaert J">J. Steyaert</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Chakravarty, R" uniqKey="Chakravarty R">R. Chakravarty</name></author><author><name sortKey="Goel, S" uniqKey="Goel S">S. Goel</name></author><author><name sortKey="Cai, W" uniqKey="Cai W">W. Cai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, N" uniqKey="Wang N">N. Wang</name></author><author><name sortKey="Shi, X" uniqKey="Shi X">X. Shi</name></author><author><name sortKey="Jiang, L" uniqKey="Jiang L">L. Jiang</name></author><author><name sortKey="Zhang, S" uniqKey="Zhang S">S. Zhang</name></author><author><name sortKey="Wang, D" uniqKey="Wang D">D. Wang</name></author><author><name sortKey="Tong, P" uniqKey="Tong P">P. Tong</name></author><author><name sortKey="Guo, D" uniqKey="Guo D">D. Guo</name></author><author><name sortKey="Fu, L" uniqKey="Fu L">L. Fu</name></author><author><name sortKey="Cui, Y" uniqKey="Cui Y">Y. Cui</name></author><author><name sortKey="Liu, X" uniqKey="Liu X">X. Liu</name></author><author><name sortKey="Arledge, K C" uniqKey="Arledge K">K. C. Arledge</name></author><author><name sortKey="Chen, Y H" uniqKey="Chen Y">Y.-H. Chen</name></author><author><name sortKey="Zhang, L" uniqKey="Zhang L">L. Zhang</name></author><author><name sortKey="Wang, X" uniqKey="Wang X">X. Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lu, G" uniqKey="Lu G">G. Lu</name></author><author><name sortKey="Hu, Y" uniqKey="Hu Y">Y. Hu</name></author><author><name sortKey="Wang, Q" uniqKey="Wang Q">Q. Wang</name></author><author><name sortKey="Qi, J" uniqKey="Qi J">J. Qi</name></author><author><name sortKey="Gao, F" uniqKey="Gao F">F. Gao</name></author><author><name sortKey="Li, Y" uniqKey="Li Y">Y. Li</name></author><author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y. Zhang</name></author><author><name sortKey="Zhang, W" uniqKey="Zhang W">W. Zhang</name></author><author><name sortKey="Yuan, Y" uniqKey="Yuan Y">Y. Yuan</name></author><author><name sortKey="Bao, J" uniqKey="Bao J">J. Bao</name></author><author><name sortKey="Zhang, B" uniqKey="Zhang B">B. Zhang</name></author><author><name sortKey="Shi, Y" uniqKey="Shi Y">Y. Shi</name></author><author><name sortKey="Yan, J" uniqKey="Yan J">J. Yan</name></author><author><name sortKey="Gao, G F" uniqKey="Gao G">G. F. Gao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, K" uniqKey="Li K">K. Li</name></author><author><name sortKey="Wohlford Lenane, C" uniqKey="Wohlford Lenane C">C. Wohlford-Lenane</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S. Perlman</name></author><author><name sortKey="Zhao, J" uniqKey="Zhao J">J. Zhao</name></author><author><name sortKey="Jewell, A K" uniqKey="Jewell A">A. K. Jewell</name></author><author><name sortKey="Reznikov, L R" uniqKey="Reznikov L">L. R. Reznikov</name></author><author><name sortKey="Gibson Corley, K N" uniqKey="Gibson Corley K">K. N. Gibson-Corley</name></author><author><name sortKey="Meyerholz, D K" uniqKey="Meyerholz D">D. K. Meyerholz</name></author><author><name sortKey="Mccray, P B" uniqKey="Mccray P">P. B. McCray</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schmidt, F I" uniqKey="Schmidt F">F. I. Schmidt</name></author><author><name sortKey="Hanke, L" uniqKey="Hanke L">L. Hanke</name></author><author><name sortKey="Morin, B" uniqKey="Morin B">B. Morin</name></author><author><name sortKey="Brewer, R" uniqKey="Brewer R">R. Brewer</name></author><author><name sortKey="Brusic, V" uniqKey="Brusic V">V. Brusic</name></author><author><name sortKey="Whelan, S P J" uniqKey="Whelan S">S. P. J. Whelan</name></author><author><name sortKey="Ploegh, H L" uniqKey="Ploegh H">H. L. Ploegh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B. L. Haagmans</name></author><author><name sortKey="Al Dhahiry, S H S" uniqKey="Al Dhahiry S">S. H. S. Al Dhahiry</name></author><author><name sortKey="Reusken, C B E M" uniqKey="Reusken C">C. B. E. M Reusken</name></author><author><name sortKey="Stalin Raj, V" uniqKey="Stalin Raj V">V. Stalin Raj</name></author><author><name sortKey="Galiano, M" uniqKey="Galiano M">M. Galiano</name></author><author><name sortKey="Myers, R" uniqKey="Myers R">R. Myers</name></author><author><name sortKey="Godeke, G J" uniqKey="Godeke G">G.-J. Godeke</name></author><author><name sortKey="Jonges, M" uniqKey="Jonges M">M. Jonges</name></author><author><name sortKey="Farag, E" uniqKey="Farag E">E. Farag</name></author><author><name sortKey="Diab, A" uniqKey="Diab A">A. Diab</name></author><author><name sortKey="Ghobashy, H" uniqKey="Ghobashy H">H. Ghobashy</name></author><author><name sortKey="Alhajri, F" uniqKey="Alhajri F">F. Alhajri</name></author><author><name sortKey="Al Thani, M" uniqKey="Al Thani M">M. Al-Thani</name></author><author><name sortKey="Al Marri, S A" uniqKey="Al Marri S">S. A. Al-Marri</name></author><author><name sortKey="Al Romaihi, H E" uniqKey="Al Romaihi H">H. E. Al Romaihi</name></author><author><name sortKey="Khal, A A" uniqKey="Khal A">A. A. Khal</name></author><author><name sortKey="Bermingham, A" uniqKey="Bermingham A">A. Bermingham</name></author><author><name sortKey="Osterhaus, A D M E" uniqKey="Osterhaus A">A. D. M. E. Osterhaus</name></author><author><name sortKey="Koopmans, M P G" uniqKey="Koopmans M">M. P. G. Koopmans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Radbruch, A" uniqKey="Radbruch A">A. Radbruch</name></author><author><name sortKey="Muehlinghaus, G" uniqKey="Muehlinghaus G">G. Muehlinghaus</name></author><author><name sortKey="Luger, E O" uniqKey="Luger E">E. O. Luger</name></author><author><name sortKey="Inamine, A" uniqKey="Inamine A">A. Inamine</name></author><author><name sortKey="Smith, K G C" uniqKey="Smith K">K. G. C. Smith</name></author><author><name sortKey="Dorner, T" uniqKey="Dorner T">T. Dörner</name></author><author><name sortKey="Hiepe, F" uniqKey="Hiepe F">F. Hiepe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ellyard, J I" uniqKey="Ellyard J">J. I. Ellyard</name></author><author><name sortKey="Avery, D T" uniqKey="Avery D">D. T. Avery</name></author><author><name sortKey="Phan, T G" uniqKey="Phan T">T. G. Phan</name></author><author><name sortKey="Hare, N J" uniqKey="Hare N">N. J. Hare</name></author><author><name sortKey="Hodgkin, P D" uniqKey="Hodgkin P">P. D. Hodgkin</name></author><author><name sortKey="Tangye, S G" uniqKey="Tangye S">S. G. Tangye</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Paramithiotis, E" uniqKey="Paramithiotis E">E. Paramithiotis</name></author><author><name sortKey="Cooper, M D" uniqKey="Cooper M">M. D. Cooper</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Manz, R A" uniqKey="Manz R">R. A. Manz</name></author><author><name sortKey="Hauser, A E" uniqKey="Hauser A">A. E. Hauser</name></author><author><name sortKey="Hiepe, F" uniqKey="Hiepe F">F. Hiepe</name></author><author><name sortKey="Radbruch, A" uniqKey="Radbruch A">A. Radbruch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nguyen, V K" uniqKey="Nguyen V">V. K. Nguyen</name></author><author><name sortKey="Hamers, R" uniqKey="Hamers R">R. Hamers</name></author><author><name sortKey="Wyns, L" uniqKey="Wyns L">L. Wyns</name></author><author><name sortKey="Muyldermans, S" uniqKey="Muyldermans S">S. Muyldermans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ying, T" uniqKey="Ying T">T. Ying</name></author><author><name sortKey="Du, L" uniqKey="Du L">L. Du</name></author><author><name sortKey="Ju, T W" uniqKey="Ju T">T. W. Ju</name></author><author><name sortKey="Prabakaran, P" uniqKey="Prabakaran P">P. Prabakaran</name></author><author><name sortKey="Lau, C C Y" uniqKey="Lau C">C. C. Y. Lau</name></author><author><name sortKey="Lu, L" uniqKey="Lu L">L. Lu</name></author><author><name sortKey="Liu, Q" uniqKey="Liu Q">Q. Liu</name></author><author><name sortKey="Wang, L" uniqKey="Wang L">L. Wang</name></author><author><name sortKey="Feng, Y" uniqKey="Feng Y">Y. Feng</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y. Wang</name></author><author><name sortKey="Zheng, B J" uniqKey="Zheng B">B.-J. Zheng</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.-Y. Yuen</name></author><author><name sortKey="Jiang, S" uniqKey="Jiang S">S. Jiang</name></author><author><name sortKey="Dimitrov, D S" uniqKey="Dimitrov D">D. S. Dimitrov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sok, D" uniqKey="Sok D">D. Sok</name></author><author><name sortKey="Le, K M" uniqKey="Le K">K. M. Le</name></author><author><name sortKey="Vadnais, M" uniqKey="Vadnais M">M. Vadnais</name></author><author><name sortKey="Saye Francisco, K L" uniqKey="Saye Francisco K">K. L. Saye-Francisco</name></author><author><name sortKey="Jardine, J G" uniqKey="Jardine J">J. G. Jardine</name></author><author><name sortKey="Torres, J L" uniqKey="Torres J">J. L. Torres</name></author><author><name sortKey="Berndsen, Z T" uniqKey="Berndsen Z">Z. T. Berndsen</name></author><author><name sortKey="Kong, L" uniqKey="Kong L">L. Kong</name></author><author><name sortKey="Stanfield, R" uniqKey="Stanfield R">R. Stanfield</name></author><author><name sortKey="Ruiz, J" uniqKey="Ruiz J">J. Ruiz</name></author><author><name sortKey="Ramos, A" uniqKey="Ramos A">A. Ramos</name></author><author><name sortKey="Liang, C H" uniqKey="Liang C">C.-H. Liang</name></author><author><name sortKey="Chen, P L" uniqKey="Chen P">P. L. Chen</name></author><author><name sortKey="Criscitiello, M F" uniqKey="Criscitiello M">M. F. Criscitiello</name></author><author><name sortKey="Mwangi, W" uniqKey="Mwangi W">W. Mwangi</name></author><author><name sortKey="Wilson, I A" uniqKey="Wilson I">I. A. Wilson</name></author><author><name sortKey="Ward, A B" uniqKey="Ward A">A. B. Ward</name></author><author><name sortKey="Smider, V V" uniqKey="Smider V">V. V. Smider</name></author><author><name sortKey="Burton, D R" uniqKey="Burton D">D. R. Burton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sim Es, E A F" uniqKey="Sim Es E">E. A. F. Simões</name></author><author><name sortKey="Devincenzo, J P" uniqKey="Devincenzo J">J. P. DeVincenzo</name></author><author><name sortKey="Boeckh, M" uniqKey="Boeckh M">M. Boeckh</name></author><author><name sortKey="Bont, L" uniqKey="Bont L">L. Bont</name></author><author><name sortKey="Crowe, J E" uniqKey="Crowe J">J. E. Crowe</name></author><author><name sortKey="Griffiths, P" uniqKey="Griffiths P">P. Griffiths</name></author><author><name sortKey="Hayden, F G" uniqKey="Hayden F">F. G. Hayden</name></author><author><name sortKey="Hodinka, R L" uniqKey="Hodinka R">R. L. Hodinka</name></author><author><name sortKey="Smyth, R L" uniqKey="Smyth R">R. L. Smyth</name></author><author><name sortKey="Spencer, K" uniqKey="Spencer K">K. Spencer</name></author><author><name sortKey="Thirstrup, S" uniqKey="Thirstrup S">S. Thirstrup</name></author><author><name sortKey="Walsh, E E" uniqKey="Walsh E">E. E. Walsh</name></author><author><name sortKey="Whitley, R J" uniqKey="Whitley R">R. J. Whitley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Song, F" uniqKey="Song F">F. Song</name></author><author><name sortKey="Fux, R" uniqKey="Fux R">R. Fux</name></author><author><name sortKey="Provacia, L B" uniqKey="Provacia L">L. B. Provacia</name></author><author><name sortKey="Volz, A" uniqKey="Volz A">A. Volz</name></author><author><name sortKey="Eickmann, M" uniqKey="Eickmann M">M. Eickmann</name></author><author><name sortKey="Becker, S" uniqKey="Becker S">S. Becker</name></author><author><name sortKey="Osterhaus, A D M E" uniqKey="Osterhaus A">A. D. M. E. Osterhaus</name></author><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B. L. Haagmans</name></author><author><name sortKey="Sutter, G" uniqKey="Sutter G">G. Sutter</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Nakabayashi, H" uniqKey="Nakabayashi H">H. Nakabayashi</name></author><author><name sortKey="Taketa, K" uniqKey="Taketa K">K. Taketa</name></author><author><name sortKey="Miyano, K" uniqKey="Miyano K">K. Miyano</name></author><author><name sortKey="Yamane, T" uniqKey="Yamane T">T. Yamane</name></author><author><name sortKey="Sato, J" uniqKey="Sato J">J. Sato</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Boheemen, S" uniqKey="Van Boheemen S">S. van Boheemen</name></author><author><name sortKey="De Graaf, M" uniqKey="De Graaf M">M. de Graaf</name></author><author><name sortKey="Lauber, C" uniqKey="Lauber C">C. Lauber</name></author><author><name sortKey="Bestebroer, T M" uniqKey="Bestebroer T">T. M. Bestebroer</name></author><author><name sortKey="Stalin Raj, V" uniqKey="Stalin Raj V">V. Stalin Raj</name></author><author><name sortKey="Zaki, A M" uniqKey="Zaki A">A. M. Zaki</name></author><author><name sortKey="Osterhaus, A D M E" uniqKey="Osterhaus A">A. D. M. E. Osterhaus</name></author><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B. L. Haagmans</name></author><author><name sortKey="Gorbalenya, A E" uniqKey="Gorbalenya A">A. E. Gorbalenya</name></author><author><name sortKey="Snijder, E J" uniqKey="Snijder E">E. J. Snijder</name></author><author><name sortKey="Fouchier, R A M" uniqKey="Fouchier R">R. A. M. Fouchier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Smits, S L" uniqKey="Smits S">S. L. Smits</name></author><author><name sortKey="De Lang, A" uniqKey="De Lang A">A. de Lang</name></author><author><name sortKey="Van Den Brand, J M A" uniqKey="Van Den Brand J">J. M. A. van den Brand</name></author><author><name sortKey="Leijten, L M" uniqKey="Leijten L">L. M. Leijten</name></author><author><name sortKey="Van Ijcken, W F" uniqKey="Van Ijcken W">W. F. van IJcken</name></author><author><name sortKey="Eijkemans, M J C" uniqKey="Eijkemans M">M. J. C. Eijkemans</name></author><author><name sortKey="Vanamerongen, G" uniqKey="Vanamerongen G">G. vanAmerongen</name></author><author><name sortKey="Kuiken, T" uniqKey="Kuiken T">T. Kuiken</name></author><author><name sortKey="Andeweg, A C" uniqKey="Andeweg A">A. C. Andeweg</name></author><author><name sortKey="Osterhaus, A D M E" uniqKey="Osterhaus A">A. D. M. E. Osterhaus</name></author><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B. L. Haagmans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Kuppeveld, F J" uniqKey="Van Kuppeveld F">F. J. van Kuppeveld</name></author><author><name sortKey="Van Der Logt, J T" uniqKey="Van Der Logt J">J. T. van der Logt</name></author><author><name sortKey="Angulo, A F" uniqKey="Angulo A">A. F. Angulo</name></author><author><name sortKey="Van Zoest, M J" uniqKey="Van Zoest M">M. J. van Zoest</name></author><author><name sortKey="Quint, W G" uniqKey="Quint W">W. G. Quint</name></author><author><name sortKey="Niesters, H G" uniqKey="Niesters H">H. G. Niesters</name></author><author><name sortKey="Galama, J M" uniqKey="Galama J">J. M. Galama</name></author><author><name sortKey="Melchers, W J" uniqKey="Melchers W">W. J. Melchers</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B. L. Haagmans</name></author><author><name sortKey="Van Den Brand, J M A" uniqKey="Van Den Brand J">J. M. A. van den Brand</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Abdiche, Y N" uniqKey="Abdiche Y">Y. N. Abdiche</name></author><author><name sortKey="Malashock, D S" uniqKey="Malashock D">D. S. Malashock</name></author><author><name sortKey="Pinkerton, A" uniqKey="Pinkerton A">A. Pinkerton</name></author><author><name sortKey="Pons, J" uniqKey="Pons J">J. Pons</name></author></analytic></biblStruct></listBibl></div1></back></TEI></pmc><pubmed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection.</title><author><name sortKey="Stalin Raj, V" sort="Stalin Raj, V" uniqKey="Stalin Raj V" first="V" last="Stalin Raj">V. Stalin Raj</name><affiliation wicri:level="3"><nlm:affiliation>Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Okba, Nisreen M A" sort="Okba, Nisreen M A" uniqKey="Okba N" first="Nisreen M A" last="Okba">Nisreen M A. Okba</name><affiliation wicri:level="3"><nlm:affiliation>Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Gutierrez Alvarez, Javier" sort="Gutierrez Alvarez, Javier" uniqKey="Gutierrez Alvarez J" first="Javier" last="Gutierrez-Alvarez">Javier Gutierrez-Alvarez</name><affiliation wicri:level="3"><nlm:affiliation>Department of Molecular and Cell Biology, National Center for Biotechnology-Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology-Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Drabek, Dubravka" sort="Drabek, Dubravka" uniqKey="Drabek D" first="Dubravka" last="Drabek">Dubravka Drabek</name><affiliation wicri:level="3"><nlm:affiliation>Department of Cell Biology, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Cell Biology, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Van Dieren, Brenda" sort="Van Dieren, Brenda" uniqKey="Van Dieren B" first="Brenda" last="Van Dieren">Brenda Van Dieren</name><affiliation wicri:level="4"><nlm:affiliation>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName><orgName type="university">Université d'Utrecht</orgName></affiliation></author><author><name sortKey="Widagdo, W" sort="Widagdo, W" uniqKey="Widagdo W" first="W" last="Widagdo">W. Widagdo</name><affiliation wicri:level="3"><nlm:affiliation>Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Lamers, Mart M" sort="Lamers, Mart M" uniqKey="Lamers M" first="Mart M" last="Lamers">Mart M. Lamers</name><affiliation wicri:level="3"><nlm:affiliation>Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Widjaja, Ivy" sort="Widjaja, Ivy" uniqKey="Widjaja I" first="Ivy" last="Widjaja">Ivy Widjaja</name><affiliation wicri:level="4"><nlm:affiliation>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName><orgName type="university">Université d'Utrecht</orgName></affiliation></author><author><name sortKey="Fernandez Delgado, Raul" sort="Fernandez Delgado, Raul" uniqKey="Fernandez Delgado R" first="Raul" last="Fernandez-Delgado">Raul Fernandez-Delgado</name><affiliation wicri:level="3"><nlm:affiliation>Department of Molecular and Cell Biology, National Center for Biotechnology-Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology-Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Sola, Isabel" sort="Sola, Isabel" uniqKey="Sola I" first="Isabel" last="Sola">Isabel Sola</name><affiliation wicri:level="3"><nlm:affiliation>Department of Molecular and Cell Biology, National Center for Biotechnology-Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology-Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Bensaid, Albert" sort="Bensaid, Albert" uniqKey="Bensaid A" first="Albert" last="Bensaid">Albert Bensaid</name><affiliation wicri:level="2"><nlm:affiliation>Institut de Recerca i Tecnologia Agroalimentàries (IRTA), Centre de Recerca en Sanitat Animal [CReSA, IRTA-Universitat Autònoma de Barcelona (UAB)], Campus de la UAB, 08193 Bellaterra, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Institut de Recerca i Tecnologia Agroalimentàries (IRTA), Centre de Recerca en Sanitat Animal [CReSA, IRTA-Universitat Autònoma de Barcelona (UAB)], Campus de la UAB, 08193 Bellaterra</wicri:regionArea><placeName><region nuts="2" type="communauté">Catalogne</region></placeName></affiliation></author><author><name sortKey="Koopmans, Marion P" sort="Koopmans, Marion P" uniqKey="Koopmans M" first="Marion P" last="Koopmans">Marion P. Koopmans</name><affiliation wicri:level="3"><nlm:affiliation>Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Segales, Joaquim" sort="Segales, Joaquim" uniqKey="Segales J" first="Joaquim" last="Segalés">Joaquim Segalés</name><affiliation wicri:level="2"><nlm:affiliation>UAB, CReSA (IRTA-UAB), Campus de la UAB, 08193 Bellaterra, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>UAB, CReSA (IRTA-UAB), Campus de la UAB, 08193 Bellaterra</wicri:regionArea><placeName><region nuts="2" type="communauté">Catalogne</region></placeName></affiliation></author><author><name sortKey="Osterhaus, Albert D M E" sort="Osterhaus, Albert D M E" uniqKey="Osterhaus A" first="Albert D M E" last="Osterhaus">Albert D M E. Osterhaus</name><affiliation wicri:level="3"><nlm:affiliation>Artemis One Health, Utrecht, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Artemis One Health, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Bosch, Berend Jan" sort="Bosch, Berend Jan" uniqKey="Bosch B" first="Berend Jan" last="Bosch">Berend Jan Bosch</name><affiliation wicri:level="4"><nlm:affiliation>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName><orgName type="university">Université d'Utrecht</orgName></affiliation></author><author><name sortKey="Enjuanes, Luis" sort="Enjuanes, Luis" uniqKey="Enjuanes L" first="Luis" last="Enjuanes">Luis Enjuanes</name><affiliation wicri:level="3"><nlm:affiliation>Department of Molecular and Cell Biology, National Center for Biotechnology-Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology-Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Haagmans, Bart L" sort="Haagmans, Bart L" uniqKey="Haagmans B" first="Bart L" last="Haagmans">Bart L. Haagmans</name><affiliation wicri:level="3"><nlm:affiliation>Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2018">2018</date><idno type="RBID">pubmed:30101189</idno><idno type="pmid">30101189</idno><idno type="doi">10.1126/sciadv.aas9667</idno><idno type="wicri:Area/PubMed/Corpus">000818</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000818</idno><idno type="wicri:Area/PubMed/Curation">000818</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000818</idno><idno type="wicri:Area/PubMed/Checkpoint">000991</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000991</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection.</title><author><name sortKey="Stalin Raj, V" sort="Stalin Raj, V" uniqKey="Stalin Raj V" first="V" last="Stalin Raj">V. Stalin Raj</name><affiliation wicri:level="3"><nlm:affiliation>Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Okba, Nisreen M A" sort="Okba, Nisreen M A" uniqKey="Okba N" first="Nisreen M A" last="Okba">Nisreen M A. Okba</name><affiliation wicri:level="3"><nlm:affiliation>Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Gutierrez Alvarez, Javier" sort="Gutierrez Alvarez, Javier" uniqKey="Gutierrez Alvarez J" first="Javier" last="Gutierrez-Alvarez">Javier Gutierrez-Alvarez</name><affiliation wicri:level="3"><nlm:affiliation>Department of Molecular and Cell Biology, National Center for Biotechnology-Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology-Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Drabek, Dubravka" sort="Drabek, Dubravka" uniqKey="Drabek D" first="Dubravka" last="Drabek">Dubravka Drabek</name><affiliation wicri:level="3"><nlm:affiliation>Department of Cell Biology, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Cell Biology, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Van Dieren, Brenda" sort="Van Dieren, Brenda" uniqKey="Van Dieren B" first="Brenda" last="Van Dieren">Brenda Van Dieren</name><affiliation wicri:level="4"><nlm:affiliation>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName><orgName type="university">Université d'Utrecht</orgName></affiliation></author><author><name sortKey="Widagdo, W" sort="Widagdo, W" uniqKey="Widagdo W" first="W" last="Widagdo">W. Widagdo</name><affiliation wicri:level="3"><nlm:affiliation>Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Lamers, Mart M" sort="Lamers, Mart M" uniqKey="Lamers M" first="Mart M" last="Lamers">Mart M. Lamers</name><affiliation wicri:level="3"><nlm:affiliation>Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Widjaja, Ivy" sort="Widjaja, Ivy" uniqKey="Widjaja I" first="Ivy" last="Widjaja">Ivy Widjaja</name><affiliation wicri:level="4"><nlm:affiliation>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName><orgName type="university">Université d'Utrecht</orgName></affiliation></author><author><name sortKey="Fernandez Delgado, Raul" sort="Fernandez Delgado, Raul" uniqKey="Fernandez Delgado R" first="Raul" last="Fernandez-Delgado">Raul Fernandez-Delgado</name><affiliation wicri:level="3"><nlm:affiliation>Department of Molecular and Cell Biology, National Center for Biotechnology-Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology-Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Sola, Isabel" sort="Sola, Isabel" uniqKey="Sola I" first="Isabel" last="Sola">Isabel Sola</name><affiliation wicri:level="3"><nlm:affiliation>Department of Molecular and Cell Biology, National Center for Biotechnology-Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology-Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Bensaid, Albert" sort="Bensaid, Albert" uniqKey="Bensaid A" first="Albert" last="Bensaid">Albert Bensaid</name><affiliation wicri:level="2"><nlm:affiliation>Institut de Recerca i Tecnologia Agroalimentàries (IRTA), Centre de Recerca en Sanitat Animal [CReSA, IRTA-Universitat Autònoma de Barcelona (UAB)], Campus de la UAB, 08193 Bellaterra, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Institut de Recerca i Tecnologia Agroalimentàries (IRTA), Centre de Recerca en Sanitat Animal [CReSA, IRTA-Universitat Autònoma de Barcelona (UAB)], Campus de la UAB, 08193 Bellaterra</wicri:regionArea><placeName><region nuts="2" type="communauté">Catalogne</region></placeName></affiliation></author><author><name sortKey="Koopmans, Marion P" sort="Koopmans, Marion P" uniqKey="Koopmans M" first="Marion P" last="Koopmans">Marion P. Koopmans</name><affiliation wicri:level="3"><nlm:affiliation>Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Segales, Joaquim" sort="Segales, Joaquim" uniqKey="Segales J" first="Joaquim" last="Segalés">Joaquim Segalés</name><affiliation wicri:level="2"><nlm:affiliation>UAB, CReSA (IRTA-UAB), Campus de la UAB, 08193 Bellaterra, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>UAB, CReSA (IRTA-UAB), Campus de la UAB, 08193 Bellaterra</wicri:regionArea><placeName><region nuts="2" type="communauté">Catalogne</region></placeName></affiliation></author><author><name sortKey="Osterhaus, Albert D M E" sort="Osterhaus, Albert D M E" uniqKey="Osterhaus A" first="Albert D M E" last="Osterhaus">Albert D M E. Osterhaus</name><affiliation wicri:level="3"><nlm:affiliation>Artemis One Health, Utrecht, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Artemis One Health, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Bosch, Berend Jan" sort="Bosch, Berend Jan" uniqKey="Bosch B" first="Berend Jan" last="Bosch">Berend Jan Bosch</name><affiliation wicri:level="4"><nlm:affiliation>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName><orgName type="university">Université d'Utrecht</orgName></affiliation></author><author><name sortKey="Enjuanes, Luis" sort="Enjuanes, Luis" uniqKey="Enjuanes L" first="Luis" last="Enjuanes">Luis Enjuanes</name><affiliation wicri:level="3"><nlm:affiliation>Department of Molecular and Cell Biology, National Center for Biotechnology-Spanish National Research Council (CNB-CSIC), Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, National Center for Biotechnology-Spanish National Research Council (CNB-CSIC), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Haagmans, Bart L" sort="Haagmans, Bart L" uniqKey="Haagmans B" first="Bart L" last="Haagmans">Bart L. Haagmans</name><affiliation wicri:level="3"><nlm:affiliation>Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author></analytic><series><title level="j">Science advances</title><idno type="eISSN">2375-2548</idno><imprint><date when="2018" type="published">2018</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Antibodies, Neutralizing (administration & dosage)</term><term>Antibodies, Neutralizing (biosynthesis)</term><term>Antibodies, Neutralizing (immunology)</term><term>Antibodies, Viral (administration & dosage)</term><term>Antibodies, Viral (biosynthesis)</term><term>Antibodies, Viral (immunology)</term><term>Camelus</term><term>Coronavirus Infections (immunology)</term><term>Coronavirus Infections (prevention & control)</term><term>Coronavirus Infections (virology)</term><term>Female</term><term>Humans</term><term>Male</term><term>Mice</term><term>Middle East Respiratory Syndrome Coronavirus (immunology)</term><term>Neutralization Tests</term><term>Protein Binding</term><term>Single-Domain Antibodies</term><term>Virus Internalization (drug effects)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Anticorps antiviraux (administration et posologie)</term><term>Anticorps antiviraux (biosynthèse)</term><term>Anticorps antiviraux (immunologie)</term><term>Anticorps neutralisants (administration et posologie)</term><term>Anticorps neutralisants (biosynthèse)</term><term>Anticorps neutralisants (immunologie)</term><term>Anticorps à domaine unique</term><term>Chameaux</term><term>Coronavirus du syndrome respiratoire du Moyen-Orient (immunologie)</term><term>Femelle</term><term>Humains</term><term>Infections à coronavirus ()</term><term>Infections à coronavirus (immunologie)</term><term>Infections à coronavirus (virologie)</term><term>Liaison aux protéines</term><term>Mâle</term><term>Pénétration virale ()</term><term>Souris</term><term>Tests de neutralisation</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Antibodies, Neutralizing</term><term>Antibodies, Viral</term></keywords><keywords scheme="MESH" type="chemical" qualifier="biosynthesis" xml:lang="en"><term>Antibodies, Neutralizing</term><term>Antibodies, Viral</term></keywords><keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Antibodies, Neutralizing</term><term>Antibodies, Viral</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Anticorps antiviraux</term><term>Anticorps neutralisants</term></keywords><keywords scheme="MESH" qualifier="biosynthèse" xml:lang="fr"><term>Anticorps antiviraux</term><term>Anticorps neutralisants</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Virus Internalization</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Anticorps antiviraux</term><term>Anticorps neutralisants</term><term>Coronavirus du syndrome respiratoire du Moyen-Orient</term><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Coronavirus Infections</term><term>Middle East Respiratory Syndrome Coronavirus</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Coronavirus Infections</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Camelus</term><term>Female</term><term>Humans</term><term>Male</term><term>Mice</term><term>Neutralization Tests</term><term>Protein Binding</term><term>Single-Domain Antibodies</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Anticorps à domaine unique</term><term>Chameaux</term><term>Femelle</term><term>Humains</term><term>Infections à coronavirus</term><term>Liaison aux protéines</term><term>Mâle</term><term>Pénétration virale</term><term>Souris</term><term>Tests de neutralisation</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Middle East respiratory syndrome coronavirus (MERS-CoV) continues to cause outbreaks in humans as a result of spillover events from dromedaries. In contrast to humans, MERS-CoV-exposed dromedaries develop only very mild infections and exceptionally potent virus-neutralizing antibody responses. These strong antibody responses may be caused by affinity maturation as a result of repeated exposure to the virus or by the fact that dromedaries-apart from conventional antibodies-have relatively unique, heavy chain-only antibodies (HCAbs). These HCAbs are devoid of light chains and have long complementarity-determining regions with unique epitope binding properties, allowing them to recognize and bind with high affinity to epitopes not recognized by conventional antibodies. Through direct cloning and expression of the variable heavy chains (VHHs) of HCAbs from the bone marrow of MERS-CoV-infected dromedaries, we identified several MERS-CoV-specific VHHs or nanobodies. In vitro, these VHHs efficiently blocked virus entry at picomolar concentrations. The selected VHHs bind with exceptionally high affinity to the receptor binding domain of the viral spike protein. Furthermore, camel/human chimeric HCAbs-composed of the camel VHH linked to a human Fc domain lacking the CH1 exon-had an extended half-life in the serum and protected mice against a lethal MERS-CoV challenge. HCAbs represent a promising alternative strategy to develop novel interventions not only for MERS-CoV but also for other emerging pathogens.</div></front></TEI></pubmed></double></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Ncbi/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001F22 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd -nk 001F22 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= MersV1
|flux= Ncbi
|étape= Merge
|type= RBID
|clé= PMC:6082650
|texte= Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/RBID.i -Sk "pubmed:30101189" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd \
| NlmPubMed2Wicri -a MersV1
| This area was generated with Dilib version V0.6.33. |  |