Middle East respiratory syndrome coronavirus disease in children.
Identifieur interne : 000D42 ( Ncbi/Merge ); précédent : 000D41; suivant : 000D43Middle East respiratory syndrome coronavirus disease in children.
Auteurs : Ziad A. Memish ; Jaffar A. Al-Tawfiq ; Abdullah Assiri ; Fahad A. Alrabiah ; Sami Al Hajjar ; Ali Albarrak ; Hesham Flemban ; Rafat F. Alhakeem ; Hatem Q. Makhdoom ; Sarah Alsubaie ; Abdullah A. Al-RabeeahSource :
- The Pediatric infectious disease journal [ 1532-0987 ] ; 2014.
Descripteurs français
- KwdFr :
- Adolescent, Coronavirus du syndrome respiratoire du Moyen-Orient, Enfant, Enfant d'âge préscolaire, Femelle, Fièvre (virologie), Humains, Infections à coronavirus (), Infections à coronavirus (diagnostic), Infections à coronavirus (virologie), Insuffisance respiratoire (virologie), Issue fatale, Maladies asymptomatiques, Mâle, Partie nasale du pharynx (virologie), Toux (virologie).
- MESH :
- diagnostic : Infections à coronavirus.
- virologie : Fièvre, Infections à coronavirus, Insuffisance respiratoire, Partie nasale du pharynx, Toux.
- Adolescent, Coronavirus du syndrome respiratoire du Moyen-Orient, Enfant, Enfant d'âge préscolaire, Femelle, Humains, Infections à coronavirus, Issue fatale, Maladies asymptomatiques, Mâle.
English descriptors
- KwdEn :
- Adolescent, Asymptomatic Diseases, Child, Child, Preschool, Coronavirus Infections (complications), Coronavirus Infections (diagnosis), Coronavirus Infections (virology), Cough (virology), Fatal Outcome, Female, Fever (virology), Humans, Male, Middle East Respiratory Syndrome Coronavirus, Nasopharynx (virology), Respiratory Insufficiency (virology).
- MESH :
- complications : Coronavirus Infections.
- diagnosis : Coronavirus Infections.
- virology : Coronavirus Infections, Cough, Fever, Nasopharynx, Respiratory Insufficiency.
- Adolescent, Asymptomatic Diseases, Child, Child, Preschool, Fatal Outcome, Female, Humans, Male, Middle East Respiratory Syndrome Coronavirus.
Abstract
In the initial description of Middle East respiratory syndrome coronavirus (MERS-CoV) infection, many affected patients were adults with underlying medical comorbidities. Data on the clinical presentation and outcome of pediatric cases are lacking. We report the clinical presentation and outcome of MERS-CoV infection in 11 pediatric patients.
DOI: 10.1097/INF.0000000000000325
PubMed: 24763193
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pubmed:24763193Le document en format XML
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Memish</name><affiliation><nlm:affiliation>From the *Al-Faisal University, Riyadh; †Saudi Aramco Medical Services Organisation, Saudi ARAMCO, Dhahran; ‡Infection Prevention and Control Program, Public Health Directorate, Ministry of Health; §King Faisal Specialist Hospital; ¶Alhada Military Hospital; ‖Communicable Disease Program, Ministry of Health; **Jeddah Regional Laboratory, Ministry of Health, Jeddah; ††College of Medicine, King Saud University; and ‡‡Minister of Health, Ministry of Health, Riyadh, Kingdom of Saudi Arabia.</nlm:affiliation><wicri:noCountry code="subField">Kingdom of Saudi Arabia</wicri:noCountry></affiliation></author><author><name sortKey="Al Tawfiq, Jaffar A" sort="Al Tawfiq, Jaffar A" uniqKey="Al Tawfiq J" first="Jaffar A" last="Al-Tawfiq">Jaffar A. 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Memish</name><affiliation><nlm:affiliation>From the *Al-Faisal University, Riyadh; †Saudi Aramco Medical Services Organisation, Saudi ARAMCO, Dhahran; ‡Infection Prevention and Control Program, Public Health Directorate, Ministry of Health; §King Faisal Specialist Hospital; ¶Alhada Military Hospital; ‖Communicable Disease Program, Ministry of Health; **Jeddah Regional Laboratory, Ministry of Health, Jeddah; ††College of Medicine, King Saud University; and ‡‡Minister of Health, Ministry of Health, Riyadh, Kingdom of Saudi Arabia.</nlm:affiliation><wicri:noCountry code="subField">Kingdom of Saudi Arabia</wicri:noCountry></affiliation></author><author><name sortKey="Al Tawfiq, Jaffar A" sort="Al Tawfiq, Jaffar A" uniqKey="Al Tawfiq J" first="Jaffar A" last="Al-Tawfiq">Jaffar A. Al-Tawfiq</name></author><author><name sortKey="Assiri, Abdullah" sort="Assiri, Abdullah" uniqKey="Assiri A" first="Abdullah" last="Assiri">Abdullah Assiri</name></author><author><name sortKey="Alrabiah, Fahad A" sort="Alrabiah, Fahad A" uniqKey="Alrabiah F" first="Fahad A" last="Alrabiah">Fahad A. Alrabiah</name></author><author><name sortKey="Al Hajjar, Sami" sort="Al Hajjar, Sami" uniqKey="Al Hajjar S" first="Sami" last="Al Hajjar">Sami Al Hajjar</name></author><author><name sortKey="Albarrak, Ali" sort="Albarrak, Ali" uniqKey="Albarrak A" first="Ali" last="Albarrak">Ali Albarrak</name></author><author><name sortKey="Flemban, Hesham" sort="Flemban, Hesham" uniqKey="Flemban H" first="Hesham" last="Flemban">Hesham Flemban</name></author><author><name sortKey="Alhakeem, Rafat F" sort="Alhakeem, Rafat F" uniqKey="Alhakeem R" first="Rafat F" last="Alhakeem">Rafat F. Alhakeem</name></author><author><name sortKey="Makhdoom, Hatem Q" sort="Makhdoom, Hatem Q" uniqKey="Makhdoom H" first="Hatem Q" last="Makhdoom">Hatem Q. Makhdoom</name></author><author><name sortKey="Alsubaie, Sarah" sort="Alsubaie, Sarah" uniqKey="Alsubaie S" first="Sarah" last="Alsubaie">Sarah Alsubaie</name></author><author><name sortKey="Al Rabeeah, Abdullah A" sort="Al Rabeeah, Abdullah A" uniqKey="Al Rabeeah A" first="Abdullah A" last="Al-Rabeeah">Abdullah A. Al-Rabeeah</name></author></analytic><series><title level="j">The Pediatric infectious disease journal</title><idno type="eISSN">1532-0987</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Asymptomatic Diseases</term><term>Child</term><term>Child, Preschool</term><term>Coronavirus Infections (complications)</term><term>Coronavirus Infections (diagnosis)</term><term>Coronavirus Infections (virology)</term><term>Cough (virology)</term><term>Fatal Outcome</term><term>Female</term><term>Fever (virology)</term><term>Humans</term><term>Male</term><term>Middle East Respiratory Syndrome Coronavirus</term><term>Nasopharynx (virology)</term><term>Respiratory Insufficiency (virology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Coronavirus du syndrome respiratoire du Moyen-Orient</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Femelle</term><term>Fièvre (virologie)</term><term>Humains</term><term>Infections à coronavirus ()</term><term>Infections à coronavirus (diagnostic)</term><term>Infections à coronavirus (virologie)</term><term>Insuffisance respiratoire (virologie)</term><term>Issue fatale</term><term>Maladies asymptomatiques</term><term>Mâle</term><term>Partie nasale du pharynx (virologie)</term><term>Toux (virologie)</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Coronavirus Infections</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Coronavirus Infections</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Fièvre</term><term>Infections à coronavirus</term><term>Insuffisance respiratoire</term><term>Partie nasale du pharynx</term><term>Toux</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term><term>Cough</term><term>Fever</term><term>Nasopharynx</term><term>Respiratory Insufficiency</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Asymptomatic Diseases</term><term>Child</term><term>Child, Preschool</term><term>Fatal Outcome</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle East Respiratory Syndrome Coronavirus</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Coronavirus du syndrome respiratoire du Moyen-Orient</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Femelle</term><term>Humains</term><term>Infections à coronavirus</term><term>Issue fatale</term><term>Maladies asymptomatiques</term><term>Mâle</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In the initial description of Middle East respiratory syndrome coronavirus (MERS-CoV) infection, many affected patients were adults with underlying medical comorbidities. Data on the clinical presentation and outcome of pediatric cases are lacking. We report the clinical presentation and outcome of MERS-CoV infection in 11 pediatric patients.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">24763193</PMID><DateCompleted><Year>2015</Year><Month>10</Month><Day>28</Day></DateCompleted><DateRevised><Year>2014</Year><Month>11</Month><Day>01</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1532-0987</ISSN><JournalIssue CitedMedium="Internet"><Volume>33</Volume><Issue>9</Issue><PubDate><Year>2014</Year><Month>Sep</Month></PubDate></JournalIssue><Title>The Pediatric infectious disease journal</Title><ISOAbbreviation>Pediatr. Infect. Dis. J.</ISOAbbreviation></Journal><ArticleTitle>Middle East respiratory syndrome coronavirus disease in children.</ArticleTitle><Pagination><MedlinePgn>904-6</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1097/INF.0000000000000325</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">In the initial description of Middle East respiratory syndrome coronavirus (MERS-CoV) infection, many affected patients were adults with underlying medical comorbidities. Data on the clinical presentation and outcome of pediatric cases are lacking. We report the clinical presentation and outcome of MERS-CoV infection in 11 pediatric patients.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">The clinical presentation, demographic and laboratory data of pediatric patients with MERS-CoV were analyzed.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">A total of 11 pediatric cases that tested positive by screening and confirmatory polymerase chain reaction for MERS-CoV were reported from Saudi Arabia. Two patients were symptomatic and the other 9 cases were asymptomatic. The median age of patients was 13 (range 2-16) years. There were 8 females and 3 males (2.7:1 ratio). One symptomatic patient died and the other symptomatic patient recovered. The diagnosis of patients was based on positive nasopharyngeal swabs on 10 patients.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">MERS-CoV disease is not limited to adults. Most cases of childhood MERS-CoV infection were asymptomatic and tested positive during contact investigation of older patients. Severe disease can occur in children with underlying conditions.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Memish</LastName><ForeName>Ziad A</ForeName><Initials>ZA</Initials><AffiliationInfo><Affiliation>From the *Al-Faisal University, Riyadh; †Saudi Aramco Medical Services Organisation, Saudi ARAMCO, Dhahran; ‡Infection Prevention and Control Program, Public Health Directorate, Ministry of Health; §King Faisal Specialist Hospital; ¶Alhada Military Hospital; ‖Communicable Disease Program, Ministry of Health; **Jeddah Regional Laboratory, Ministry of Health, Jeddah; ††College of Medicine, King Saud University; and ‡‡Minister of Health, Ministry of Health, Riyadh, Kingdom of Saudi Arabia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Al-Tawfiq</LastName><ForeName>Jaffar A</ForeName><Initials>JA</Initials></Author><Author ValidYN="Y"><LastName>Assiri</LastName><ForeName>Abdullah</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>AlRabiah</LastName><ForeName>Fahad A</ForeName><Initials>FA</Initials></Author><Author ValidYN="Y"><LastName>Al Hajjar</LastName><ForeName>Sami</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Albarrak</LastName><ForeName>Ali</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Flemban</LastName><ForeName>Hesham</ForeName><Initials>H</Initials></Author><Author ValidYN="Y"><LastName>Alhakeem</LastName><ForeName>Rafat F</ForeName><Initials>RF</Initials></Author><Author ValidYN="Y"><LastName>Makhdoom</LastName><ForeName>Hatem Q</ForeName><Initials>HQ</Initials></Author><Author ValidYN="Y"><LastName>Alsubaie</LastName><ForeName>Sarah</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Al-Rabeeah</LastName><ForeName>Abdullah A</ForeName><Initials>AA</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Pediatr Infect Dis J</MedlineTA><NlmUniqueID>8701858</NlmUniqueID><ISSNLinking>0891-3668</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D058070" MajorTopicYN="N">Asymptomatic Diseases</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002675" MajorTopicYN="N">Child, Preschool</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003371" MajorTopicYN="N">Cough</DescriptorName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017809" MajorTopicYN="N">Fatal Outcome</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005334" MajorTopicYN="N">Fever</DescriptorName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D065207" MajorTopicYN="Y">Middle East Respiratory Syndrome Coronavirus</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009305" MajorTopicYN="N">Nasopharynx</DescriptorName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012131" MajorTopicYN="N">Respiratory Insufficiency</DescriptorName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2014</Year><Month>4</Month><Day>26</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2014</Year><Month>4</Month><Day>26</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2015</Year><Month>10</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">24763193</ArticleId><ArticleId IdType="doi">10.1097/INF.0000000000000325</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list></list><tree><noCountry><name sortKey="Al Hajjar, Sami" sort="Al Hajjar, Sami" uniqKey="Al Hajjar S" first="Sami" last="Al Hajjar">Sami Al Hajjar</name><name sortKey="Al Rabeeah, Abdullah A" sort="Al Rabeeah, Abdullah A" uniqKey="Al Rabeeah A" first="Abdullah A" last="Al-Rabeeah">Abdullah A. Al-Rabeeah</name><name sortKey="Al Tawfiq, Jaffar A" sort="Al Tawfiq, Jaffar A" uniqKey="Al Tawfiq J" first="Jaffar A" last="Al-Tawfiq">Jaffar A. Al-Tawfiq</name><name sortKey="Albarrak, Ali" sort="Albarrak, Ali" uniqKey="Albarrak A" first="Ali" last="Albarrak">Ali Albarrak</name><name sortKey="Alhakeem, Rafat F" sort="Alhakeem, Rafat F" uniqKey="Alhakeem R" first="Rafat F" last="Alhakeem">Rafat F. Alhakeem</name><name sortKey="Alrabiah, Fahad A" sort="Alrabiah, Fahad A" uniqKey="Alrabiah F" first="Fahad A" last="Alrabiah">Fahad A. Alrabiah</name><name sortKey="Alsubaie, Sarah" sort="Alsubaie, Sarah" uniqKey="Alsubaie S" first="Sarah" last="Alsubaie">Sarah Alsubaie</name><name sortKey="Assiri, Abdullah" sort="Assiri, Abdullah" uniqKey="Assiri A" first="Abdullah" last="Assiri">Abdullah Assiri</name><name sortKey="Flemban, Hesham" sort="Flemban, Hesham" uniqKey="Flemban H" first="Hesham" last="Flemban">Hesham Flemban</name><name sortKey="Makhdoom, Hatem Q" sort="Makhdoom, Hatem Q" uniqKey="Makhdoom H" first="Hatem Q" last="Makhdoom">Hatem Q. Makhdoom</name><name sortKey="Memish, Ziad A" sort="Memish, Ziad A" uniqKey="Memish Z" first="Ziad A" last="Memish">Ziad A. Memish</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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