Stereochemical Sequence Dictates Unimolecular Diblock Copolymer Assembly.
Identifieur interne : 001D18 ( Ncbi/Checkpoint ); précédent : 001D17; suivant : 001D19Stereochemical Sequence Dictates Unimolecular Diblock Copolymer Assembly.
Auteurs : Matthew R. Golder [États-Unis] ; Yivan Jiang [États-Unis] ; Paul E. Teichen [États-Unis] ; Hung V-T Nguyen [États-Unis] ; Wencong Wang [États-Unis] ; Nicole Milos [États-Unis] ; Seth A. Freedman [États-Unis] ; Adam P. Willard [États-Unis] ; Jeremiah A. Johnson [États-Unis]Source :
- Journal of the American Chemical Society [ 1520-5126 ] ; 2018.
Descripteurs français
- KwdFr :
- MESH :
- synthèse chimique : Polymères.
- Conformation moléculaire, Polymères, Stéréoisomérie.
English descriptors
- KwdEn :
- MESH :
- chemical , chemical synthesis : Polymers.
- chemical , chemistry : Polymers.
- Molecular Conformation, Stereoisomerism.
Abstract
Deciphering the significance of length, sequence, and stereochemistry in block copolymer self-assembly remains an ongoing challenge. A dearth of methods to access uniform block co-oligomers/polymers with precise stereochemical sequences has precluded such studies. Here, we develop iterative exponential growth methods for the synthesis of a small library of unimolecular stereoisomeric diblock 32-mers. X-ray scattering reveals that stereochemistry modulates the phase behavior of these polymers, which we rationalize based on simulations carried out on a theoretical model system. This work demonstrates that stereochemical sequence can play a crucial role in unimolecular polymer self-assembly.
DOI: 10.1021/jacs.7b12696
PubMed: 29356516
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000A13
- to stream PubMed, to step Curation: 000A13
- to stream PubMed, to step Checkpoint: 000761
- to stream Ncbi, to step Merge: 001D18
- to stream Ncbi, to step Curation: 001D18
Links to Exploration step
pubmed:29356516Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Stereochemical Sequence Dictates Unimolecular Diblock Copolymer Assembly.</title><author><name sortKey="Golder, Matthew R" sort="Golder, Matthew R" uniqKey="Golder M" first="Matthew R" last="Golder">Matthew R. Golder</name><affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143</wicri:regionArea><wicri:noRegion>Massachusetts 02143</wicri:noRegion></affiliation></author><author><name sortKey="Jiang, Yivan" sort="Jiang, Yivan" uniqKey="Jiang Y" first="Yivan" last="Jiang">Yivan Jiang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143</wicri:regionArea><wicri:noRegion>Massachusetts 02143</wicri:noRegion></affiliation></author><author><name sortKey="Teichen, Paul E" sort="Teichen, Paul E" uniqKey="Teichen P" first="Paul E" last="Teichen">Paul E. Teichen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143</wicri:regionArea><wicri:noRegion>Massachusetts 02143</wicri:noRegion></affiliation></author><author><name sortKey="Nguyen, Hung V T" sort="Nguyen, Hung V T" uniqKey="Nguyen H" first="Hung V-T" last="Nguyen">Hung V-T Nguyen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143</wicri:regionArea><wicri:noRegion>Massachusetts 02143</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Wencong" sort="Wang, Wencong" uniqKey="Wang W" first="Wencong" last="Wang">Wencong Wang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143</wicri:regionArea><wicri:noRegion>Massachusetts 02143</wicri:noRegion></affiliation></author><author><name sortKey="Milos, Nicole" sort="Milos, Nicole" uniqKey="Milos N" first="Nicole" last="Milos">Nicole Milos</name><affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143</wicri:regionArea><wicri:noRegion>Massachusetts 02143</wicri:noRegion></affiliation></author><author><name sortKey="Freedman, Seth A" sort="Freedman, Seth A" uniqKey="Freedman S" first="Seth A" last="Freedman">Seth A. Freedman</name><affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143</wicri:regionArea><wicri:noRegion>Massachusetts 02143</wicri:noRegion></affiliation></author><author><name sortKey="Willard, Adam P" sort="Willard, Adam P" uniqKey="Willard A" first="Adam P" last="Willard">Adam P. Willard</name><affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143</wicri:regionArea><wicri:noRegion>Massachusetts 02143</wicri:noRegion></affiliation></author><author><name sortKey="Johnson, Jeremiah A" sort="Johnson, Jeremiah A" uniqKey="Johnson J" first="Jeremiah A" last="Johnson">Jeremiah A. Johnson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143</wicri:regionArea><wicri:noRegion>Massachusetts 02143</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2018">2018</date><idno type="RBID">pubmed:29356516</idno><idno type="pmid">29356516</idno><idno type="doi">10.1021/jacs.7b12696</idno><idno type="wicri:Area/PubMed/Corpus">000A13</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000A13</idno><idno type="wicri:Area/PubMed/Curation">000A13</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000A13</idno><idno type="wicri:Area/PubMed/Checkpoint">000761</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000761</idno><idno type="wicri:Area/Ncbi/Merge">001D18</idno><idno type="wicri:Area/Ncbi/Curation">001D18</idno><idno type="wicri:Area/Ncbi/Checkpoint">001D18</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Stereochemical Sequence Dictates Unimolecular Diblock Copolymer Assembly.</title><author><name sortKey="Golder, Matthew R" sort="Golder, Matthew R" uniqKey="Golder M" first="Matthew R" last="Golder">Matthew R. Golder</name><affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143</wicri:regionArea><wicri:noRegion>Massachusetts 02143</wicri:noRegion></affiliation></author><author><name sortKey="Jiang, Yivan" sort="Jiang, Yivan" uniqKey="Jiang Y" first="Yivan" last="Jiang">Yivan Jiang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143</wicri:regionArea><wicri:noRegion>Massachusetts 02143</wicri:noRegion></affiliation></author><author><name sortKey="Teichen, Paul E" sort="Teichen, Paul E" uniqKey="Teichen P" first="Paul E" last="Teichen">Paul E. Teichen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143</wicri:regionArea><wicri:noRegion>Massachusetts 02143</wicri:noRegion></affiliation></author><author><name sortKey="Nguyen, Hung V T" sort="Nguyen, Hung V T" uniqKey="Nguyen H" first="Hung V-T" last="Nguyen">Hung V-T Nguyen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143</wicri:regionArea><wicri:noRegion>Massachusetts 02143</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Wencong" sort="Wang, Wencong" uniqKey="Wang W" first="Wencong" last="Wang">Wencong Wang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143</wicri:regionArea><wicri:noRegion>Massachusetts 02143</wicri:noRegion></affiliation></author><author><name sortKey="Milos, Nicole" sort="Milos, Nicole" uniqKey="Milos N" first="Nicole" last="Milos">Nicole Milos</name><affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143</wicri:regionArea><wicri:noRegion>Massachusetts 02143</wicri:noRegion></affiliation></author><author><name sortKey="Freedman, Seth A" sort="Freedman, Seth A" uniqKey="Freedman S" first="Seth A" last="Freedman">Seth A. Freedman</name><affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143</wicri:regionArea><wicri:noRegion>Massachusetts 02143</wicri:noRegion></affiliation></author><author><name sortKey="Willard, Adam P" sort="Willard, Adam P" uniqKey="Willard A" first="Adam P" last="Willard">Adam P. Willard</name><affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143</wicri:regionArea><wicri:noRegion>Massachusetts 02143</wicri:noRegion></affiliation></author><author><name sortKey="Johnson, Jeremiah A" sort="Johnson, Jeremiah A" uniqKey="Johnson J" first="Jeremiah A" last="Johnson">Jeremiah A. Johnson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143, United States.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, Massachusetts Institute of Technology , Cambridge, Massachusetts 02143</wicri:regionArea><wicri:noRegion>Massachusetts 02143</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of the American Chemical Society</title><idno type="eISSN">1520-5126</idno><imprint><date when="2018" type="published">2018</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Molecular Conformation</term><term>Polymers (chemical synthesis)</term><term>Polymers (chemistry)</term><term>Stereoisomerism</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Conformation moléculaire</term><term>Polymères ()</term><term>Polymères (synthèse chimique)</term><term>Stéréoisomérie</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemical synthesis" xml:lang="en"><term>Polymers</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Polymers</term></keywords><keywords scheme="MESH" qualifier="synthèse chimique" xml:lang="fr"><term>Polymères</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Molecular Conformation</term><term>Stereoisomerism</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Conformation moléculaire</term><term>Polymères</term><term>Stéréoisomérie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Deciphering the significance of length, sequence, and stereochemistry in block copolymer self-assembly remains an ongoing challenge. A dearth of methods to access uniform block co-oligomers/polymers with precise stereochemical sequences has precluded such studies. Here, we develop iterative exponential growth methods for the synthesis of a small library of unimolecular stereoisomeric diblock 32-mers. X-ray scattering reveals that stereochemistry modulates the phase behavior of these polymers, which we rationalize based on simulations carried out on a theoretical model system. This work demonstrates that stereochemical sequence can play a crucial role in unimolecular polymer self-assembly.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country></list><tree><country name="États-Unis"><noRegion><name sortKey="Golder, Matthew R" sort="Golder, Matthew R" uniqKey="Golder M" first="Matthew R" last="Golder">Matthew R. Golder</name></noRegion><name sortKey="Freedman, Seth A" sort="Freedman, Seth A" uniqKey="Freedman S" first="Seth A" last="Freedman">Seth A. Freedman</name><name sortKey="Jiang, Yivan" sort="Jiang, Yivan" uniqKey="Jiang Y" first="Yivan" last="Jiang">Yivan Jiang</name><name sortKey="Johnson, Jeremiah A" sort="Johnson, Jeremiah A" uniqKey="Johnson J" first="Jeremiah A" last="Johnson">Jeremiah A. Johnson</name><name sortKey="Milos, Nicole" sort="Milos, Nicole" uniqKey="Milos N" first="Nicole" last="Milos">Nicole Milos</name><name sortKey="Nguyen, Hung V T" sort="Nguyen, Hung V T" uniqKey="Nguyen H" first="Hung V-T" last="Nguyen">Hung V-T Nguyen</name><name sortKey="Teichen, Paul E" sort="Teichen, Paul E" uniqKey="Teichen P" first="Paul E" last="Teichen">Paul E. Teichen</name><name sortKey="Wang, Wencong" sort="Wang, Wencong" uniqKey="Wang W" first="Wencong" last="Wang">Wencong Wang</name><name sortKey="Willard, Adam P" sort="Willard, Adam P" uniqKey="Willard A" first="Adam P" last="Willard">Adam P. Willard</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Ncbi/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001D18 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd -nk 001D18 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= MersV1
|flux= Ncbi
|étape= Checkpoint
|type= RBID
|clé= pubmed:29356516
|texte= Stereochemical Sequence Dictates Unimolecular Diblock Copolymer Assembly.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/RBID.i -Sk "pubmed:29356516" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a MersV1
| This area was generated with Dilib version V0.6.33. |  |