Mild encephalopathy with reversible splenial lesion in a patient with influenza A infection--first report in an adult patient in the USA.
Identifieur interne : 001131 ( Ncbi/Checkpoint ); précédent : 001130; suivant : 001132Mild encephalopathy with reversible splenial lesion in a patient with influenza A infection--first report in an adult patient in the USA.
Auteurs : Jonathan Wang [États-Unis] ; Earl Stewart [États-Unis] ; Kwame Dapaah-Afriyie [États-Unis] ; Arkadiy Finn [États-Unis]Source :
- BMJ case reports [ 1757-790X ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Antiviraux (usage thérapeutique), Corps calleux (anatomopathologie), Corps calleux (virologie), Diagnostic différentiel, Encéphalopathies (), Encéphalopathies (diagnostic), Encéphalopathies (virologie), Grippe humaine (), Grippe humaine (diagnostic), Humains, Mâle, Oséltamivir (usage thérapeutique), Pronostic.
- MESH :
- anatomopathologie : Corps calleux.
- diagnostic : Encéphalopathies, Grippe humaine.
- usage thérapeutique : Antiviraux, Oséltamivir.
- virologie : Corps calleux, Encéphalopathies.
- Adulte d'âge moyen, Diagnostic différentiel, Encéphalopathies, Grippe humaine, Humains, Mâle, Pronostic.
English descriptors
- KwdEn :
- Antiviral Agents (therapeutic use), Brain Diseases (complications), Brain Diseases (diagnosis), Brain Diseases (virology), Corpus Callosum (pathology), Corpus Callosum (virology), Diagnosis, Differential, Humans, Influenza, Human (complications), Influenza, Human (diagnosis), Male, Middle Aged, Oseltamivir (therapeutic use), Prognosis.
- MESH :
- chemical , therapeutic use : Antiviral Agents, Oseltamivir.
- complications : Brain Diseases, Influenza, Human.
- diagnosis : Brain Diseases, Influenza, Human.
- pathology : Corpus Callosum.
- virology : Brain Diseases, Corpus Callosum.
- Diagnosis, Differential, Humans, Male, Middle Aged, Prognosis.
Abstract
We present a case of a 51-year-old man with panhypopituarism who developed clinically mild encephalopathy with a lesion in the splenium of the corpus callosum, in the setting of acute influenza A infection. The patient's initial presentation included hypernatraemia due to pre-existing iatrogenic central diabetes insipidus. Despite adequate treatment of hypernatraemia, his course was complicated by otherwise unexplained mild encephalopathy. Brain MRI revealed a diffusion restricted lesion in the splenium of the corpus callosum. This presentation was consistent with mild encephalopathy with reversible splenial lesion (MERS). The patient subsequently tested positive for influenza A. This is the first reported case of MERS syndrome due to influenza A infection in an adult patient in the USA. Mild encephalopathy associated with influenza A infection and a reversible splenial lesion of the corpus callosum has a favourable prognosis and resolves spontaneously.
DOI: 10.1136/bcr-2015-210197
PubMed: 26038383
Affiliations:
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infection. The patient's initial presentation included hypernatraemia due to pre-existing iatrogenic central diabetes insipidus. Despite adequate treatment of hypernatraemia, his course was complicated by otherwise unexplained mild encephalopathy. Brain MRI revealed a diffusion restricted lesion in the splenium of the corpus callosum. This presentation was consistent with mild encephalopathy with reversible splenial lesion (MERS). The patient subsequently tested positive for influenza A. This is the first reported case of MERS syndrome due to influenza A infection in an adult patient in the USA. Mild encephalopathy associated with influenza A infection and a reversible splenial lesion of the corpus callosum has a favourable prognosis and resolves spontaneously. </div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Rhode Island</li></region><settlement><li>Providence (Rhode Island)</li></settlement><orgName><li>Université Brown</li></orgName></list><tree><country name="États-Unis"><region name="Rhode Island"><name sortKey="Wang, Jonathan" sort="Wang, Jonathan" uniqKey="Wang J" first="Jonathan" last="Wang">Jonathan Wang</name></region><name sortKey="Dapaah Afriyie, Kwame" sort="Dapaah Afriyie, Kwame" uniqKey="Dapaah Afriyie K" first="Kwame" last="Dapaah-Afriyie">Kwame Dapaah-Afriyie</name><name sortKey="Finn, Arkadiy" sort="Finn, Arkadiy" uniqKey="Finn A" first="Arkadiy" last="Finn">Arkadiy Finn</name><name sortKey="Stewart, Earl" sort="Stewart, Earl" uniqKey="Stewart E" first="Earl" last="Stewart">Earl Stewart</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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