Serveur d'exploration MERS

Attention, ce site est en cours de développement !
Attention, site généré par des moyens informatiques à partir de corpus bruts.
Les informations ne sont donc pas validées.

Dendritic cells: their significance in health and disease

Identifieur interne : 003612 ( Main/Merge ); précédent : 003611; suivant : 003613

Dendritic cells: their significance in health and disease

Auteurs : Robert Keller [Suisse]

Source :

RBID : ISTEX:33F66D4F12B00EC1B0B2F374155687393D8F14B5

English descriptors

Abstract

Abstract: Dendritic cells (DCs) represent a heterogenous population of professional antigen-presenting cells. Precursor cells move via the blood to peripheral tissues. These immature DCs can take up invading pathogens and then rapidly migrate to the draining secondary lymphoid organs. Converted into antigen-presenting mature DCs, these cells are able to prime naive T cells and to initiate an adoptive immune response. The extraordinary functional profile suggests that, under certain preconditions, DCs may represent an ideal vector in the immunotherapy of cancer and infectious diseases

Url:
DOI: 10.1016/S0165-2478(01)00247-4

Links toward previous steps (curation, corpus...)


Links to Exploration step

ISTEX:33F66D4F12B00EC1B0B2F374155687393D8F14B5

Le document en format XML

<record>
<TEI wicri:istexFullTextTei="biblStruct">
<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en">Dendritic cells: their significance in health and disease</title>
<author>
<name sortKey="Keller, Robert" sort="Keller, Robert" uniqKey="Keller R" first="Robert" last="Keller">Robert Keller</name>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:33F66D4F12B00EC1B0B2F374155687393D8F14B5</idno>
<date when="2001" year="2001">2001</date>
<idno type="doi">10.1016/S0165-2478(01)00247-4</idno>
<idno type="url">https://api.istex.fr/ark:/67375/6H6-X46QRDZQ-K/fulltext.pdf</idno>
<idno type="wicri:Area/Istex/Corpus">001E44</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001E44</idno>
<idno type="wicri:Area/Istex/Curation">001E44</idno>
<idno type="wicri:Area/Istex/Checkpoint">000E96</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000E96</idno>
<idno type="wicri:doubleKey">0165-2478:2001:Keller R:dendritic:cells:their</idno>
<idno type="wicri:Area/Main/Merge">003612</idno>
</publicationStmt>
<sourceDesc>
<biblStruct>
<analytic>
<title level="a" type="main" xml:lang="en">Dendritic cells: their significance in health and disease</title>
<author>
<name sortKey="Keller, Robert" sort="Keller, Robert" uniqKey="Keller R" first="Robert" last="Keller">Robert Keller</name>
<affiliation wicri:level="4">
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Pathology, Institute of Experimental Immunology, University of Zurich, CH-8091 Zurich</wicri:regionArea>
<orgName type="university">Université de Zurich</orgName>
<placeName>
<settlement type="city">Zurich</settlement>
<region nuts="3" type="region">Canton de Zurich</region>
</placeName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series>
<title level="j">Immunology Letters</title>
<title level="j" type="abbrev">IMLET</title>
<idno type="ISSN">0165-2478</idno>
<imprint>
<publisher>ELSEVIER</publisher>
<date type="published" when="2001">2001</date>
<biblScope unit="volume">78</biblScope>
<biblScope unit="issue">3</biblScope>
<biblScope unit="page" from="113">113</biblScope>
<biblScope unit="page" to="122">122</biblScope>
</imprint>
<idno type="ISSN">0165-2478</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt>
<idno type="ISSN">0165-2478</idno>
</seriesStmt>
</fileDesc>
<profileDesc>
<textClass>
<keywords scheme="KwdEn" xml:lang="en">
<term>APC, antigen-presenting cells</term>
<term>Ag, antigen</term>
<term>Antigen capture and presentation by dendritic cells</term>
<term>CTLs, cytotoxic T lymphocytes</term>
<term>DC-SIGN, a DC-specific C-type lectin</term>
<term>DC-STAMP, a DC-specific transmembrane protein</term>
<term>DCs, dendritic cells</term>
<term>Dendritic cell trafficking and maturation</term>
<term>Dendritic cells in clinically relevant situations</term>
<term>GC, germinal center</term>
<term>GM-CSF, granulocyte-macrophage colony-stimulating factor</term>
<term>HSP, heat shock protein</term>
<term>IFN, interferon</term>
<term>IL, interleukin</term>
<term>ILT3, myeloid cell surface molecule of the Ig superfamily involved in Ag processing</term>
<term>LCs, Langerhans cells</term>
<term>MDCs, myeloid DCs</term>
<term>MLR, mixed lymphocyte reaction</term>
<term>NK, natural killer cells</term>
<term>PDCs, plasmacytoid DCs</term>
<term>SCF, stem cell factor</term>
<term>TAP, the transporter associated with Ag processing</term>
<term>TCR, T cell receptor</term>
<term>TGFβ, transforming growth factor β</term>
<term>TNFα, tumor necrosis factor α</term>
<term>Th, T helper cells</term>
<term>The dendritic cell system</term>
</keywords>
<keywords scheme="Teeft" xml:lang="en">
<term>Adhesion molecules</term>
<term>Antitumor immunotherapy</term>
<term>Autoimmune disease</term>
<term>Banchereau</term>
<term>Blood monocytes</term>
<term>Bone marrow</term>
<term>Caux</term>
<term>Cell area</term>
<term>Cell factor</term>
<term>Cell interaction</term>
<term>Cell lysates</term>
<term>Cell memory</term>
<term>Cell responses</term>
<term>Chemokines</term>
<term>Constitutive chemokines</term>
<term>Cord blood</term>
<term>Costimulatory molecules</term>
<term>Ctls</term>
<term>Cytokine</term>
<term>Dendritic</term>
<term>Dendritic cell 6accines</term>
<term>Dendritic cell system</term>
<term>Dendritic cells</term>
<term>Elsevier science</term>
<term>Flt3l</term>
<term>Functional properties</term>
<term>Germinal center</term>
<term>Growth factor</term>
<term>Growth factors</term>
<term>Heat shock protein</term>
<term>Helper cells</term>
<term>Hematopoietic</term>
<term>Hematopoietic progenitors</term>
<term>Hematopoietic system</term>
<term>Hengartner</term>
<term>House dust mite</term>
<term>Human blood</term>
<term>Human mdcs</term>
<term>Immune</term>
<term>Immune response</term>
<term>Immune responses</term>
<term>Immunol</term>
<term>Immunology</term>
<term>Immunotherapy</term>
<term>Important role</term>
<term>Infectious diseases</term>
<term>Innate immunity</term>
<term>Keller</term>
<term>Keller immunology letters</term>
<term>Langerhans cells</term>
<term>Lanzavecchia</term>
<term>Life cycle</term>
<term>Liposomal peptide vaccine</term>
<term>Long hand</term>
<term>Ludewig</term>
<term>Lymph nodes</term>
<term>Lymphocyte</term>
<term>Lymphoid</term>
<term>Major histocompatibility</term>
<term>Maturation</term>
<term>Maturation process</term>
<term>Mdcs</term>
<term>Molecule</term>
<term>Monocyte</term>
<term>Mononuclear phagocytes</term>
<term>Myeloid</term>
<term>Normal tissues</term>
<term>Other cell types</term>
<term>Other hand</term>
<term>Pathogen</term>
<term>Pathway</term>
<term>Pdcs</term>
<term>Peptide</term>
<term>Peripheral blood</term>
<term>Peripheral tissues</term>
<term>Precursor</term>
<term>Progenitor</term>
<term>Progenitor cells</term>
<term>Receptor</term>
<term>Secondary lymphoid organ</term>
<term>Secondary lymphoid organs</term>
<term>Subset</term>
<term>Trace population</term>
<term>Tumor necrosis factor</term>
<term>Tumor vaccination</term>
<term>Various stages</term>
<term>Viral</term>
<term>Viral vectors</term>
<term>Waal malefyt</term>
<term>Zinkernagel</term>
</keywords>
</textClass>
<langUsage>
<language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">Abstract: Dendritic cells (DCs) represent a heterogenous population of professional antigen-presenting cells. Precursor cells move via the blood to peripheral tissues. These immature DCs can take up invading pathogens and then rapidly migrate to the draining secondary lymphoid organs. Converted into antigen-presenting mature DCs, these cells are able to prime naive T cells and to initiate an adoptive immune response. The extraordinary functional profile suggests that, under certain preconditions, DCs may represent an ideal vector in the immunotherapy of cancer and infectious diseases</div>
</front>
</TEI>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003612 | SxmlIndent | more

Ou

HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 003612 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    MersV1
   |flux=    Main
   |étape=   Merge
   |type=    RBID
   |clé=     ISTEX:33F66D4F12B00EC1B0B2F374155687393D8F14B5
   |texte=   Dendritic cells: their significance in health and disease
}}

Wicri

This area was generated with Dilib version V0.6.33.
Data generation: Mon Apr 20 23:26:43 2020. Site generation: Sat Mar 27 09:06:09 2021