Therapeutic Options for Middle East Respiratory Syndrome Coronavirus (MERS-CoV) – possible lessons from a systematic review of SARS-CoV therapy
Identifieur interne : 001F00 ( Main/Merge ); précédent : 001E99; suivant : 001F01Therapeutic Options for Middle East Respiratory Syndrome Coronavirus (MERS-CoV) – possible lessons from a systematic review of SARS-CoV therapy
Auteurs : Hisham Momattin [Arabie saoudite] ; Khurram Mohammed [Arabie saoudite] ; Alimuddin Zumla [Royaume-Uni] ; Ziad A. Memish [Arabie saoudite] ; Jaffar A. Al-Tawfiq [États-Unis]Source :
- International Journal of Infectious Diseases [ 1201-9712 ] ; 2013.
Descripteurs français
- KwdFr :
- Antiviraux (usage thérapeutique), Essais contrôlés randomisés comme sujet, Humains, Infections à coronavirus (traitement médicamenteux), Infections à coronavirus (virologie), Interféron alpha (usage thérapeutique), Lopinavir (usage thérapeutique), Ritonavir (usage thérapeutique), Résultat thérapeutique, Syndrome respiratoire aigu sévère (traitement médicamenteux), Syndrome respiratoire aigu sévère (virologie), Virus du SRAS.
- MESH :
- traitement médicamenteux : Infections à coronavirus, Syndrome respiratoire aigu sévère.
- usage thérapeutique : Antiviraux, Interféron alpha, Lopinavir, Ritonavir.
- virologie : Infections à coronavirus, Syndrome respiratoire aigu sévère.
- Essais contrôlés randomisés comme sujet, Humains, Résultat thérapeutique, Virus du SRAS.
English descriptors
- KwdEn :
- Antiviral Agents (therapeutic use), Coronavirus Infections (drug therapy), Coronavirus Infections (virology), Humans, Interferon-alpha (therapeutic use), Lopinavir (therapeutic use), Randomized Controlled Trials as Topic, Ritonavir (therapeutic use), SARS Virus, Severe Acute Respiratory Syndrome (drug therapy), Severe Acute Respiratory Syndrome (virology), Treatment Outcome.
- MESH :
- chemical , therapeutic use : Antiviral Agents, Interferon-alpha, Lopinavir, Ritonavir.
- drug therapy : Coronavirus Infections, Severe Acute Respiratory Syndrome.
- virology : Coronavirus Infections, Severe Acute Respiratory Syndrome.
- Humans, Randomized Controlled Trials as Topic, SARS Virus, Treatment Outcome.
Abstract
The Middle East Respiratory Syndrome coronavirus (MERS-CoV) has been detected in a number of countries in the Middle East and Europe with an apparently high mortality rate. It is phylogenetically related to the SARS coronavirus and has also been associated with severe respiratory illness as well as nosocomial transmission in healthcare settings. Current international recommendations do not support any specific therapies; however, there are a number of agents, which were used during the SARS epidemic of 2003. It is possible that these might be active against the related MERS coronavirus. We have reviewed the literature on the safety and efficacy of therapies used in patients with SARS with a view to their potential use in patients with MERS-CoV infections.
Url:
DOI: 10.1016/j.ijid.2013.07.002
PubMed: 23993766
PubMed Central: 7110699
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PMC:7110699Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>The Middle East Respiratory Syndrome coronavirus (MERS-CoV) has been detected in a number of countries in the Middle East and Europe with an apparently high mortality rate. It is phylogenetically related to the SARS coronavirus and has also been associated with severe respiratory illness as well as nosocomial transmission in healthcare settings. Current international recommendations do not support any specific therapies; however, there are a number of agents, which were used during the SARS epidemic of 2003. It is possible that these might be active against the related MERS coronavirus. We have reviewed the literature on the safety and efficacy of therapies used in patients with SARS with a view to their potential use in patients with MERS-CoV infections.</p>
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</back>
</TEI>
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