Size Matters: Chemical Synthesis of a Homogenous Arabinogalactan 92-mer.
Identifieur interne : 000B93 ( Main/Merge ); précédent : 000B92; suivant : 000B94Size Matters: Chemical Synthesis of a Homogenous Arabinogalactan 92-mer.
Auteurs : Maciej A. Walczak [États-Unis] ; Feng Zhu [États-Unis]Source :
- Chembiochem : a European journal of chemical biology [ 1439-7633 ] ; 2017.
Descripteurs français
- KwdFr :
- MESH :
- métabolisme : Mycobacterium tuberculosis, Paroi cellulaire.
- synthèse chimique : Galactanes.
- Galactanes, Morpholines, Méthanesulfonates, Oligosaccharides.
English descriptors
- KwdEn :
- MESH :
- chemical , chemical synthesis : Galactans.
- chemical , chemistry : Galactans, Mesylates, Morpholines, Oligosaccharides.
- metabolism : Cell Wall, Mycobacterium tuberculosis.
Abstract
31+30+31: Ye and colleagues have synthesized a branched 92-mer of arabinogalactan-a major component of the cell wall of M. tuberculosis-by linking a linear oligogalactan 30-mer with two d-arabinofuranose 31-mers. Their approach capitalizes on sequential, one-pot glycosylation reactions that result in a rapid increase in molecular complexity and efficient synthesis of a branched oligosaccharide.
DOI: 10.1002/cbic.201700311
PubMed: 28628733
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pubmed:28628733Le document en format XML
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Walczak</name><affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry and Biochemistry, University of Colorado, 215 UCB, Boulder, CO, 80309, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry and Biochemistry, University of Colorado, 215 UCB, Boulder, CO, 80309</wicri:regionArea><wicri:noRegion>80309</wicri:noRegion></affiliation></author><author><name sortKey="Zhu, Feng" sort="Zhu, Feng" uniqKey="Zhu F" first="Feng" last="Zhu">Feng Zhu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Chemistry and Biochemistry, University of Colorado, 215 UCB, Boulder, CO, 80309, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry and Biochemistry, University of Colorado, 215 UCB, Boulder, CO, 80309</wicri:regionArea><wicri:noRegion>80309</wicri:noRegion></affiliation></author></analytic><series><title level="j">Chembiochem : a European journal of chemical biology</title><idno type="eISSN">1439-7633</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cell Wall (metabolism)</term><term>Galactans (chemical synthesis)</term><term>Galactans (chemistry)</term><term>Mesylates (chemistry)</term><term>Morpholines (chemistry)</term><term>Mycobacterium tuberculosis (metabolism)</term><term>Oligosaccharides (chemistry)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Galactanes ()</term><term>Galactanes (synthèse chimique)</term><term>Morpholines ()</term><term>Mycobacterium tuberculosis (métabolisme)</term><term>Méthanesulfonates ()</term><term>Oligosaccharides ()</term><term>Paroi cellulaire (métabolisme)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemical synthesis" xml:lang="en"><term>Galactans</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Galactans</term><term>Mesylates</term><term>Morpholines</term><term>Oligosaccharides</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Cell Wall</term><term>Mycobacterium tuberculosis</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Mycobacterium tuberculosis</term><term>Paroi cellulaire</term></keywords><keywords scheme="MESH" qualifier="synthèse chimique" xml:lang="fr"><term>Galactanes</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Galactanes</term><term>Morpholines</term><term>Méthanesulfonates</term><term>Oligosaccharides</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">31+30+31: Ye and colleagues have synthesized a branched 92-mer of arabinogalactan-a major component of the cell wall of M. tuberculosis-by linking a linear oligogalactan 30-mer with two d-arabinofuranose 31-mers. Their approach capitalizes on sequential, one-pot glycosylation reactions that result in a rapid increase in molecular complexity and efficient synthesis of a branched oligosaccharide.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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