Recent insights into the development of therapeutics against coronavirus diseases by targeting N protein
Identifieur interne : 001597 ( Main/Exploration ); précédent : 001596; suivant : 001598Recent insights into the development of therapeutics against coronavirus diseases by targeting N protein
Auteurs : Chung-Ke Chang [Taïwan] ; Shou-Chen Lo [Taïwan] ; Yong-Sheng Wang [Taïwan] ; Ming-Hon Hou [Taïwan]Source :
- Drug Discovery Today [ 1359-6446 ] ; 2015.
Descripteurs français
- KwdFr :
- MESH :
- métabolisme : Infections à coronavirus, Protéines nucléocapside.
- pharmacologie : Antiviraux.
- traitement médicamenteux : Infections à coronavirus.
- usage thérapeutique : Antiviraux.
- Animaux, Humains, Protéines nucléocapside.
English descriptors
- KwdEn :
- MESH :
- chemical , chemistry : Nucleocapsid Proteins.
- chemical , metabolism : Nucleocapsid Proteins.
- chemical , pharmacology : Antiviral Agents.
- chemical , therapeutic use : Antiviral Agents.
- drug therapy : Coronavirus Infections.
- metabolism : Coronavirus Infections.
- Animals, Humans.
Abstract
Coronavirus nucleocapsid proteins are appealing drug targets against coronavirus-induced diseases. A variety of compounds targeting the coronavirus nucleocapsid protein have been developed. Many of these compounds show potential antiviral activity.
Url:
DOI: 10.1016/j.drudis.2015.11.015
PubMed: 26691874
PubMed Central: 7108309
Affiliations:
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Le document en format XML
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<series><title level="j">Drug Discovery Today</title>
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<term>Antiviral Agents (therapeutic use)</term>
<term>Coronavirus Infections (drug therapy)</term>
<term>Coronavirus Infections (metabolism)</term>
<term>Humans</term>
<term>Nucleocapsid Proteins (chemistry)</term>
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<term>Infections à coronavirus (métabolisme)</term>
<term>Infections à coronavirus (traitement médicamenteux)</term>
<term>Protéines nucléocapside ()</term>
<term>Protéines nucléocapside (métabolisme)</term>
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<front><div type="abstract" xml:lang="en"><title>Highlights</title>
<p><list list-type="simple" id="lis0005"><list-item id="lsti0005"><label>•</label>
<p id="par0005">Coronavirus nucleocapsid proteins are appealing drug targets against coronavirus-induced diseases.</p>
</list-item>
<list-item id="lsti0010"><label>•</label>
<p id="par0010">A variety of compounds targeting the coronavirus nucleocapsid protein have been developed.</p>
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<list-item id="lsti0015"><label>•</label>
<p id="par0015">Many of these compounds show potential antiviral activity.</p>
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<affiliations><list><country><li>Taïwan</li>
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<tree><country name="Taïwan"><noRegion><name sortKey="Chang, Chung Ke" sort="Chang, Chung Ke" uniqKey="Chang C" first="Chung-Ke" last="Chang">Chung-Ke Chang</name>
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<name sortKey="Hou, Ming Hon" sort="Hou, Ming Hon" uniqKey="Hou M" first="Ming-Hon" last="Hou">Ming-Hon Hou</name>
<name sortKey="Hou, Ming Hon" sort="Hou, Ming Hon" uniqKey="Hou M" first="Ming-Hon" last="Hou">Ming-Hon Hou</name>
<name sortKey="Lo, Shou Chen" sort="Lo, Shou Chen" uniqKey="Lo S" first="Shou-Chen" last="Lo">Shou-Chen Lo</name>
<name sortKey="Wang, Yong Sheng" sort="Wang, Yong Sheng" uniqKey="Wang Y" first="Yong-Sheng" last="Wang">Yong-Sheng Wang</name>
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