Sparse evidence of MERS-CoV infection among animal workers living in Southern Saudi Arabia during 2012
Identifieur interne : 001A81 ( Main/Exploration ); précédent : 001A80; suivant : 001A82Sparse evidence of MERS-CoV infection among animal workers living in Southern Saudi Arabia during 2012
Auteurs : Ziad A. Memish [Arabie saoudite] ; Ahmad Alsahly [Arabie saoudite] ; Malak Al Masri [Arabie saoudite] ; Gary L. Heil [États-Unis] ; Benjamin D. Anderson [États-Unis] ; Malik Peiris [Hong Kong] ; Salah Uddin Khan [États-Unis, Bangladesh] ; Gregory C. Gray [États-Unis]Source :
- Influenza and Other Respiratory Viruses [ 1750-2640 ] ; 2014.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Animaux, Anticorps antiviraux (sang), Arabie saoudite (épidémiologie), Chameaux, Coronavirus du syndrome respiratoire du Moyen-Orient (immunologie), Femelle, Humains, Infections à coronavirus (immunologie), Infections à coronavirus (transmission), Infections à coronavirus (épidémiologie), Jeune adulte, Mâle, Sujet âgé, Sujet âgé de 80 ans ou plus, Tests de neutralisation, Études séroépidémiologiques.
- MESH :
- immunologie : Coronavirus du syndrome respiratoire du Moyen-Orient, Infections à coronavirus.
- sang : Anticorps antiviraux.
- épidémiologie : Arabie saoudite, Infections à coronavirus.
- Adolescent, Adulte, Adulte d'âge moyen, Animaux, Chameaux, Femelle, Humains, Jeune adulte, Mâle, Sujet âgé, Sujet âgé de 80 ans ou plus, Tests de neutralisation, Études séroépidémiologiques.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Aged, 80 and over, Animals, Antibodies, Viral (blood), Camelus, Coronavirus Infections (epidemiology), Coronavirus Infections (immunology), Coronavirus Infections (transmission), Female, Humans, Male, Middle Aged, Middle East Respiratory Syndrome Coronavirus (immunology), Neutralization Tests, Saudi Arabia (epidemiology), Seroepidemiologic Studies, Young Adult.
- MESH :
- chemical , blood : Antibodies, Viral.
- epidemiology : Coronavirus Infections, Saudi Arabia.
- immunology : Coronavirus Infections, Middle East Respiratory Syndrome Coronavirus.
- transmission : Coronavirus Infections.
- Adolescent, Adult, Aged, Aged, 80 and over, Animals, Camelus, Female, Humans, Male, Middle Aged, Neutralization Tests, Seroepidemiologic Studies, Young Adult.
Abstract
Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging viral pathogen that primarily causes respiratory illness. We conducted a seroprevalence study of banked human serum samples collected in 2012 from Southern Saudi Arabia. Sera from 300 animal workers (17% with daily camel exposure) and 50 non-animal-exposed controls were examined for serological evidence of MERS-CoV infection by a pseudoparticle MERS-CoV spike protein neutralization assay. None of the sera reproducibly neutralized the MERS-CoV-pseudotyped lentiviral vector. These data suggest that serological evidence of zoonotic transmission of MERS-CoV was not common among animal workers in Southern Saudi Arabia during July 2012.
Url:
DOI: 10.1111/irv.12287
PubMed: 25470665
PubMed Central: 4353318
Affiliations:
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Le document en format XML
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<term>Adult</term>
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<term>Aged, 80 and over</term>
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<term>Antibodies, Viral (blood)</term>
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<term>Coronavirus Infections (epidemiology)</term>
<term>Coronavirus Infections (immunology)</term>
<term>Coronavirus Infections (transmission)</term>
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<term>Humains</term>
<term>Infections à coronavirus (immunologie)</term>
<term>Infections à coronavirus (transmission)</term>
<term>Infections à coronavirus (épidémiologie)</term>
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<front><div type="abstract" xml:lang="en"><p>Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging viral pathogen that primarily causes respiratory illness. We conducted a seroprevalence study of banked human serum samples collected in 2012 from Southern Saudi Arabia. Sera from 300 animal workers (17% with daily camel exposure) and 50 non-animal-exposed controls were examined for serological evidence of MERS-CoV infection by a pseudoparticle MERS-CoV spike protein neutralization assay. None of the sera reproducibly neutralized the MERS-CoV-pseudotyped lentiviral vector. These data suggest that serological evidence of zoonotic transmission of MERS-CoV was not common among animal workers in Southern Saudi Arabia during July 2012.</p>
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<name sortKey="Alsahly, Ahmad" sort="Alsahly, Ahmad" uniqKey="Alsahly A" first="Ahmad" last="Alsahly">Ahmad Alsahly</name>
<name sortKey="Masri, Malak Al" sort="Masri, Malak Al" uniqKey="Masri M" first="Malak Al" last="Masri">Malak Al Masri</name>
</country>
<country name="États-Unis"><region name="Floride"><name sortKey="Heil, Gary L" sort="Heil, Gary L" uniqKey="Heil G" first="Gary L" last="Heil">Gary L. Heil</name>
</region>
<name sortKey="Anderson, Benjamin D" sort="Anderson, Benjamin D" uniqKey="Anderson B" first="Benjamin D" last="Anderson">Benjamin D. Anderson</name>
<name sortKey="Gray, Gregory C" sort="Gray, Gregory C" uniqKey="Gray G" first="Gregory C" last="Gray">Gregory C. Gray</name>
<name sortKey="Khan, Salah Uddin" sort="Khan, Salah Uddin" uniqKey="Khan S" first="Salah Uddin" last="Khan">Salah Uddin Khan</name>
</country>
<country name="Hong Kong"><noRegion><name sortKey="Peiris, Malik" sort="Peiris, Malik" uniqKey="Peiris M" first="Malik" last="Peiris">Malik Peiris</name>
</noRegion>
</country>
<country name="Bangladesh"><noRegion><name sortKey="Khan, Salah Uddin" sort="Khan, Salah Uddin" uniqKey="Khan S" first="Salah Uddin" last="Khan">Salah Uddin Khan</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>
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