A novel human coronavirus: Middle East respiratory syndrome human coronavirus
Identifieur interne : 002065 ( Main/Exploration ); précédent : 002064; suivant : 002066A novel human coronavirus: Middle East respiratory syndrome human coronavirus
Auteurs : Heyuan Geng ; Wenjie TanSource :
- Science China. Life Sciences [ 1674-7305 ] ; 2013.
Descripteurs français
- KwdFr :
- ADN viral (génétique), Adulte, Adulte d'âge moyen, Coronavirus (génétique), Coronavirus (isolement et purification), Coronavirus (pathogénicité), Génome viral, Humains, Infections de l'appareil respiratoire (virologie), Infections à coronavirus (virologie), Moyen Orient, Mâle, Phylogénie, Sujet âgé, Syndrome, Séquence nucléotidique.
- MESH :
- génétique : ADN viral, Coronavirus.
- isolement et purification : Coronavirus.
- pathogénicité : Coronavirus.
- virologie : Infections de l'appareil respiratoire, Infections à coronavirus.
- Adulte, Adulte d'âge moyen, Génome viral, Humains, Moyen Orient, Mâle, Phylogénie, Sujet âgé, Syndrome, Séquence nucléotidique.
English descriptors
- KwdEn :
- MESH :
- chemical , genetics : DNA, Viral.
- geographic : Middle East.
- genetics : Coronavirus.
- isolation & purification : Coronavirus.
- pathogenicity : Coronavirus.
- virology : Coronavirus Infections, Respiratory Tract Infections.
- Adult, Aged, Base Sequence, Genome, Viral, Humans, Male, Middle Aged, Phylogeny, Syndrome.
Abstract
In 2012, a novel coronavirus, initially named as human coronavirus EMC (HCoV-EMC) but recently renamed as Middle East respiratory syndrome human coronavirus (MERS-CoV), was identified in patients who suffered severe acute respiratory infection and subsequent renal failure that resulted in death. Ongoing epidemiological investigations together with retrospective studies have found 61 laboratory-confirmed cases of infection with this novel coronavirus, including 34 deaths to date. This novel coronavirus is culturable and two complete genome sequences are now available. Furthermore, molecular detection and indirect immunofluorescence assay have been developed. The present paper summarises the limited recent advances of this novel human coronavirus, including its discovery, genomic characterisation and detection.
Url:
DOI: 10.1007/s11427-013-4519-8
PubMed: 23917839
PubMed Central: 7089429
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>In 2012, a novel coronavirus, initially named as human coronavirus EMC (HCoV-EMC) but recently renamed as Middle East respiratory syndrome human coronavirus (MERS-CoV), was identified in patients who suffered severe acute respiratory infection and subsequent renal failure that resulted in death. Ongoing epidemiological investigations together with retrospective studies have found 61 laboratory-confirmed cases of infection with this novel coronavirus, including 34 deaths to date. This novel coronavirus is culturable and two complete genome sequences are now available. Furthermore, molecular detection and indirect immunofluorescence assay have been developed. The present paper summarises the limited recent advances of this novel human coronavirus, including its discovery, genomic characterisation and detection.</p>
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