A novel human coronavirus: Middle East respiratory syndrome human coronavirus
Identifieur interne : 000531 ( Pmc/Corpus ); précédent : 000530; suivant : 000532A novel human coronavirus: Middle East respiratory syndrome human coronavirus
Auteurs : Heyuan Geng ; Wenjie TanSource :
- Science China. Life Sciences [ 1674-7305 ] ; 2013.
Abstract
In 2012, a novel coronavirus, initially named as human coronavirus EMC (HCoV-EMC) but recently renamed as Middle East respiratory syndrome human coronavirus (MERS-CoV), was identified in patients who suffered severe acute respiratory infection and subsequent renal failure that resulted in death. Ongoing epidemiological investigations together with retrospective studies have found 61 laboratory-confirmed cases of infection with this novel coronavirus, including 34 deaths to date. This novel coronavirus is culturable and two complete genome sequences are now available. Furthermore, molecular detection and indirect immunofluorescence assay have been developed. The present paper summarises the limited recent advances of this novel human coronavirus, including its discovery, genomic characterisation and detection.
Url:
DOI: 10.1007/s11427-013-4519-8
PubMed: 23917839
PubMed Central: 7089429
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A novel human coronavirus: Middle East respiratory syndrome human coronavirus</title><author><name sortKey="Geng, Heyuan" sort="Geng, Heyuan" uniqKey="Geng H" first="Heyuan" last="Geng">Heyuan Geng</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Tan, Wenjie" sort="Tan, Wenjie" uniqKey="Tan W" first="Wenjie" last="Tan">Wenjie Tan</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23917839</idno><idno type="pmc">7089429</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7089429</idno><idno type="RBID">PMC:7089429</idno><idno type="doi">10.1007/s11427-013-4519-8</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">000531</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000531</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">A novel human coronavirus: Middle East respiratory syndrome human coronavirus</title><author><name sortKey="Geng, Heyuan" sort="Geng, Heyuan" uniqKey="Geng H" first="Heyuan" last="Geng">Heyuan Geng</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Tan, Wenjie" sort="Tan, Wenjie" uniqKey="Tan W" first="Wenjie" last="Tan">Wenjie Tan</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author></analytic><series><title level="j">Science China. Life Sciences</title><idno type="ISSN">1674-7305</idno><idno type="eISSN">1869-1889</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>In 2012, a novel coronavirus, initially named as human coronavirus EMC (HCoV-EMC) but recently renamed as Middle East respiratory syndrome human coronavirus (MERS-CoV), was identified in patients who suffered severe acute respiratory infection and subsequent renal failure that resulted in death. Ongoing epidemiological investigations together with retrospective studies have found 61 laboratory-confirmed cases of infection with this novel coronavirus, including 34 deaths to date. This novel coronavirus is culturable and two complete genome sequences are now available. Furthermore, molecular detection and indirect immunofluorescence assay have been developed. The present paper summarises the limited recent advances of this novel human coronavirus, including its discovery, genomic characterisation and detection.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y Guan</name></author><author><name sortKey="Zheng, B J" uniqKey="Zheng B">B J Zheng</name></author><author><name sortKey="He, Y Q" uniqKey="He Y">Y Q He</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Der Hoek, L" uniqKey="Van Der Hoek L">L van der Hoek</name></author><author><name sortKey="Pyrc, K" uniqKey="Pyrc K">K Pyrc</name></author><author><name sortKey="Jebbink, M F" uniqKey="Jebbink M">M F Jebbink</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Woo, P C Y" uniqKey="Woo P">P C Y Woo</name></author><author><name sortKey="Lau, S K P" uniqKey="Lau S">S K P Lau</name></author><author><name sortKey="Chu, 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Sci China Life Sci</journal-id><journal-id journal-id-type="iso-abbrev">Sci China Life Sci</journal-id><journal-title-group><journal-title>Science China. Life Sciences</journal-title></journal-title-group><issn pub-type="ppub">1674-7305</issn><issn pub-type="epub">1869-1889</issn><publisher><publisher-name>Science China Press</publisher-name><publisher-loc>Beijing</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">23917839</article-id><article-id pub-id-type="pmc">7089429</article-id><article-id pub-id-type="publisher-id">4519</article-id><article-id pub-id-type="doi">10.1007/s11427-013-4519-8</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review</subject></subj-group></article-categories><title-group><article-title>A novel human coronavirus: Middle East respiratory syndrome human coronavirus</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Geng</surname><given-names>HeYuan</given-names></name><xref ref-type="aff" rid="Aff1"></xref></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Tan</surname><given-names>WenJie</given-names></name><address><email>tanwj28@yahoo.cn</email></address><xref ref-type="aff" rid="Aff1"></xref></contrib><aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.198530.6</institution-id><institution-id institution-id-type="ISNI">0000000088032373</institution-id><institution>Biotech Center for Viral Disease Emergency, Key Laboratory of Medical Virology and Viral Diseases Prevention and Control, Ministry of Health, National Institute for Viral Disease Control and Prevention,</institution><institution>Chinese Center for Disease Control and Prevention,</institution></institution-wrap>Beijing, 102206 China</aff></contrib-group><pub-date pub-type="epub"><day>7</day><month>8</month><year>2013</year></pub-date><pub-date pub-type="pmc-release"><day>7</day><month>8</month><year>2013</year></pub-date><pub-date pub-type="ppub"><year>2013</year></pub-date><volume>56</volume><issue>8</issue><fpage>683</fpage><lpage>687</lpage><history><date date-type="received"><day>25</day><month>5</month><year>2013</year></date><date date-type="accepted"><day>15</day><month>6</month><year>2013</year></date></history><permissions><copyright-statement>© The Author(s) 2013</copyright-statement><license license-type="OpenAccess"><license-p><bold>Open Access</bold>This article is distributed under the terms of the Creative Commons Attribution 2.0 International License (<ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/2.0">https://creativecommons.org/licenses/by/2.0</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions><abstract id="Abs1"><p>In 2012, a novel coronavirus, initially named as human coronavirus EMC (HCoV-EMC) but recently renamed as Middle East respiratory syndrome human coronavirus (MERS-CoV), was identified in patients who suffered severe acute respiratory infection and subsequent renal failure that resulted in death. Ongoing epidemiological investigations together with retrospective studies have found 61 laboratory-confirmed cases of infection with this novel coronavirus, including 34 deaths to date. This novel coronavirus is culturable and two complete genome sequences are now available. Furthermore, molecular detection and indirect immunofluorescence assay have been developed. The present paper summarises the limited recent advances of this novel human coronavirus, including its discovery, genomic characterisation and detection.</p></abstract><kwd-group xml:lang="en"><title>Keywords</title><kwd>HCoV-EMC</kwd><kwd>MERS-CoV</kwd><kwd>genomic characterisation</kwd><kwd>molecular detection</kwd></kwd-group><custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name><meta-value>© Science in China Press and Springer-Verlag GmbH 2013</meta-value></custom-meta></custom-meta-group></article-meta></front><back><fn-group><fn><p>This article is published with open access at Springerlink.com</p></fn></fn-group><ref-list id="Bib1"><title>References</title><ref id="CR1"><label>1</label><element-citation publication-type="book"><person-group person-group-type="author"><collab>Virus taxonomy</collab></person-group><source>classification and nomenclature of viruses: ninth report of the International Committee of Taxonomy of 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