Histopathologic Evaluation and Scoring of Viral Lung Infection
Identifieur interne : 000548 ( Main/Exploration ); précédent : 000547; suivant : 000549Histopathologic Evaluation and Scoring of Viral Lung Infection
Auteurs :Source :
- MERS Coronavirus ; 2019.
Abstract
Emergent coronaviruses such as MERS-CoV and SARS-CoV can cause significant morbidity and mortality in infected individuals. Lung infection is a common clinical feature and contributes to disease severity as well as viral transmission. Animal models are often required to study viral infections and therapies, especially during an initial outbreak. Histopathology studies allow for identification of lesions and affected cell types to better understand viral pathogenesis and clarify effective therapies. Use of immunostaining allows detection of presumed viral receptors and viral tropism for cells can be evaluated to correlate with lesions. In the lung, lesions and immunostaining can be qualitatively described to define the cell types, microanatomic location, and type of changes seen. These features are important and necessary, but this approach can have limitations when comparing treatment groups. Semiquantitative and quantitative tissue scores are more rigorous as these provide the ability to statistically compare groups and increase the reproducibility and rigor of the study. This review describes principles, approaches, and resources that can be useful to evaluate coronavirus lung infection, focusing on MER-CoV infection as the principal example.
Url:
DOI: 10.1007/978-1-0716-0211-9_16
PubMed: 31883098
PubMed Central: 7123785
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000189
- to stream Pmc, to step Curation: 000189
- to stream Pmc, to step Checkpoint: 000291
- to stream PubMed, to step Corpus: 000303
- to stream PubMed, to step Curation: 000303
- to stream PubMed, to step Checkpoint: 000187
- to stream Ncbi, to step Merge: 002462
- to stream Ncbi, to step Curation: 002462
- to stream Ncbi, to step Checkpoint: 002462
- to stream Main, to step Merge: 000551
- to stream Main, to step Curation: 000548
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Histopathologic Evaluation and Scoring of Viral Lung Infection</title></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">31883098</idno><idno type="pmc">7123785</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7123785</idno><idno type="RBID">PMC:7123785</idno><idno type="doi">10.1007/978-1-0716-0211-9_16</idno><date when="2019">2019</date><idno type="wicri:Area/Pmc/Corpus">000189</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000189</idno><idno type="wicri:Area/Pmc/Curation">000189</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000189</idno><idno type="wicri:Area/Pmc/Checkpoint">000291</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000291</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:31883098</idno><idno type="wicri:Area/PubMed/Corpus">000303</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000303</idno><idno type="wicri:Area/PubMed/Curation">000303</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000303</idno><idno type="wicri:Area/PubMed/Checkpoint">000187</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000187</idno><idno type="wicri:Area/Ncbi/Merge">002462</idno><idno type="wicri:Area/Ncbi/Curation">002462</idno><idno type="wicri:Area/Ncbi/Checkpoint">002462</idno><idno type="wicri:Area/Main/Merge">000551</idno><idno type="wicri:Area/Main/Curation">000548</idno><idno type="wicri:Area/Main/Exploration">000548</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Histopathologic Evaluation and Scoring of Viral Lung Infection</title></analytic><series><title level="j">MERS Coronavirus</title><imprint><date when="2019">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="Par1">Emergent coronaviruses such as MERS-CoV and SARS-CoV can cause significant morbidity and mortality in infected individuals. Lung infection is a common clinical feature and contributes to disease severity as well as viral transmission. Animal models are often required to study viral infections and therapies, especially during an initial outbreak. Histopathology studies allow for identification of lesions and affected cell types to better understand viral pathogenesis and clarify effective therapies. Use of immunostaining allows detection of presumed viral receptors and viral tropism for cells can be evaluated to correlate with lesions. In the lung, lesions and immunostaining can be qualitatively described to define the cell types, microanatomic location, and type of changes seen. These features are important and necessary, but this approach can have limitations when comparing treatment groups. Semiquantitative and quantitative tissue scores are more rigorous as these provide the ability to statistically compare groups and increase the reproducibility and rigor of the study. This review describes principles, approaches, and resources that can be useful to evaluate coronavirus lung infection, focusing on MER-CoV infection as the principal example.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Booth, Cm" uniqKey="Booth C">CM Booth</name></author><author><name sortKey="Matukas, Lm" uniqKey="Matukas L">LM Matukas</name></author><author><name sortKey="Tomlinson, Ga" uniqKey="Tomlinson G">GA Tomlinson</name></author><author><name sortKey="Rachlis, Ar" uniqKey="Rachlis A">AR Rachlis</name></author><author><name sortKey="Rose, Db" uniqKey="Rose D">DB Rose</name></author><author><name sortKey="Dwosh, Ha" uniqKey="Dwosh H">HA Dwosh</name></author><author><name sortKey="Walmsley, Sl" uniqKey="Walmsley S">SL Walmsley</name></author><author><name sortKey="Mazzulli, T" uniqKey="Mazzulli T">T Mazzulli</name></author><author><name sortKey="Avendano, M" uniqKey="Avendano M">M Avendano</name></author><author><name sortKey="Derkach, P" uniqKey="Derkach P">P Derkach</name></author><author><name sortKey="Ephtimios, Ie" uniqKey="Ephtimios I">IE Ephtimios</name></author><author><name sortKey="Kitai, I" uniqKey="Kitai I">I Kitai</name></author><author><name sortKey="Mederski, Bd" uniqKey="Mederski B">BD Mederski</name></author><author><name sortKey="Shadowitz, Sb" uniqKey="Shadowitz S">SB Shadowitz</name></author><author><name sortKey="Gold, Wl" uniqKey="Gold W">WL Gold</name></author><author><name sortKey="Hawryluck, La" uniqKey="Hawryluck L">LA Hawryluck</name></author><author><name sortKey="Rea, E" uniqKey="Rea E">E Rea</name></author><author><name sortKey="Chenkin, Js" uniqKey="Chenkin J">JS Chenkin</name></author><author><name sortKey="Cescon, Dw" uniqKey="Cescon D">DW Cescon</name></author><author><name sortKey="Poutanen, Sm" uniqKey="Poutanen S">SM Poutanen</name></author><author><name sortKey="Detsky, As" uniqKey="Detsky A">AS Detsky</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zumla, A" uniqKey="Zumla A">A Zumla</name></author><author><name sortKey="Hui, Ds" uniqKey="Hui D">DS Hui</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S Perlman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Khalid, I" uniqKey="Khalid I">I Khalid</name></author><author><name sortKey="Alraddadi, Bm" uniqKey="Alraddadi B">BM Alraddadi</name></author><author><name sortKey="Dairi, Y" uniqKey="Dairi Y">Y Dairi</name></author><author><name sortKey="Khalid, Tj" uniqKey="Khalid T">TJ Khalid</name></author><author><name sortKey="Kadri, M" uniqKey="Kadri M">M Kadri</name></author><author><name sortKey="Alshukairi, An" uniqKey="Alshukairi A">AN Alshukairi</name></author><author><name sortKey="Qushmaq, Ia" uniqKey="Qushmaq I">IA Qushmaq</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ng, Dl" uniqKey="Ng D">DL Ng</name></author><author><name sortKey="Al Hosani, F" uniqKey="Al Hosani F">F Al Hosani</name></author><author><name sortKey="Keating, Mk" uniqKey="Keating M">MK Keating</name></author><author><name sortKey="Gerber, Si" uniqKey="Gerber S">SI Gerber</name></author><author><name sortKey="Jones, Tl" uniqKey="Jones T">TL Jones</name></author><author><name sortKey="Metcalfe, Mg" uniqKey="Metcalfe M">MG Metcalfe</name></author><author><name sortKey="Tong, S" uniqKey="Tong S">S Tong</name></author><author><name sortKey="Tao, Y" uniqKey="Tao Y">Y Tao</name></author><author><name sortKey="Alami, Nn" uniqKey="Alami N">NN Alami</name></author><author><name sortKey="Haynes, Lm" uniqKey="Haynes L">LM Haynes</name></author><author><name sortKey="Mutei, Ma" uniqKey="Mutei M">MA Mutei</name></author><author><name sortKey="Abdel Wareth, L" uniqKey="Abdel Wareth L">L Abdel-Wareth</name></author><author><name sortKey="Uyeki, Tm" uniqKey="Uyeki T">TM Uyeki</name></author><author><name sortKey="Swerdlow, Dl" uniqKey="Swerdlow D">DL Swerdlow</name></author><author><name sortKey="Barakat, M" uniqKey="Barakat M">M Barakat</name></author><author><name sortKey="Zaki, Sr" uniqKey="Zaki S">SR Zaki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Peiris, Js" uniqKey="Peiris J">JS Peiris</name></author><author><name sortKey="Chu, Cm" uniqKey="Chu C">CM Chu</name></author><author><name sortKey="Cheng, Vc" uniqKey="Cheng V">VC Cheng</name></author><author><name sortKey="Chan, Ks" uniqKey="Chan K">KS Chan</name></author><author><name sortKey="Hung, If" uniqKey="Hung I">IF Hung</name></author><author><name sortKey="Poon, Ll" uniqKey="Poon L">LL Poon</name></author><author><name sortKey="Law, Ki" uniqKey="Law K">KI Law</name></author><author><name sortKey="Tang, Bs" uniqKey="Tang B">BS Tang</name></author><author><name sortKey="Hon, Ty" uniqKey="Hon T">TY Hon</name></author><author><name sortKey="Chan, Cs" uniqKey="Chan C">CS Chan</name></author><author><name sortKey="Chan, Kh" uniqKey="Chan K">KH Chan</name></author><author><name sortKey="Ng, Js" uniqKey="Ng J">JS Ng</name></author><author><name sortKey="Zheng, Bj" uniqKey="Zheng B">BJ Zheng</name></author><author><name sortKey="Ng, Wl" uniqKey="Ng W">WL Ng</name></author><author><name sortKey="Lai, Rw" uniqKey="Lai R">RW Lai</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y Guan</name></author><author><name sortKey="Yuen, Ky" uniqKey="Yuen K">KY Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cockrell, As" uniqKey="Cockrell A">AS Cockrell</name></author><author><name sortKey="Johnson, Jc" uniqKey="Johnson J">JC Johnson</name></author><author><name sortKey="Moore, In" uniqKey="Moore I">IN Moore</name></author><author><name sortKey="Liu, Dx" uniqKey="Liu D">DX Liu</name></author><author><name sortKey="Bock, Kw" uniqKey="Bock K">KW Bock</name></author><author><name sortKey="Douglas, Mg" uniqKey="Douglas M">MG Douglas</name></author><author><name sortKey="Graham, Rl" uniqKey="Graham R">RL Graham</name></author><author><name sortKey="Solomon, J" uniqKey="Solomon J">J Solomon</name></author><author><name sortKey="Torzewski, L" uniqKey="Torzewski L">L Torzewski</name></author><author><name sortKey="Bartos, C" uniqKey="Bartos C">C Bartos</name></author><author><name sortKey="Hart, R" uniqKey="Hart R">R Hart</name></author><author><name sortKey="Baric, Rs" uniqKey="Baric R">RS Baric</name></author><author><name sortKey="Johnson, Rf" uniqKey="Johnson R">RF Johnson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hua, X" uniqKey="Hua X">X Hua</name></author><author><name sortKey="Vijay, R" uniqKey="Vijay R">R Vijay</name></author><author><name sortKey="Channappanavar, R" uniqKey="Channappanavar R">R Channappanavar</name></author><author><name sortKey="Athmer, J" uniqKey="Athmer J">J Athmer</name></author><author><name sortKey="Meyerholz, Dk" uniqKey="Meyerholz D">DK Meyerholz</name></author><author><name sortKey="Pagedar, N" uniqKey="Pagedar N">N Pagedar</name></author><author><name sortKey="Tilley, S" uniqKey="Tilley S">S Tilley</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S Perlman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, K" uniqKey="Li K">K Li</name></author><author><name sortKey="Wohlford Lenane, C" uniqKey="Wohlford Lenane C">C Wohlford-Lenane</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S Perlman</name></author><author><name sortKey="Zhao, J" uniqKey="Zhao J">J Zhao</name></author><author><name sortKey="Jewell, Ak" uniqKey="Jewell A">AK Jewell</name></author><author><name sortKey="Reznikov, Lr" uniqKey="Reznikov L">LR Reznikov</name></author><author><name sortKey="Gibson Corley, Kn" uniqKey="Gibson Corley K">KN Gibson-Corley</name></author><author><name sortKey="Meyerholz, Dk" uniqKey="Meyerholz D">DK Meyerholz</name></author><author><name sortKey="Mccray, Pb" uniqKey="Mccray P">PB McCray</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Menachery, Vd" uniqKey="Menachery V">VD Menachery</name></author><author><name sortKey="Yount, Bl" uniqKey="Yount B">BL Yount</name></author><author><name sortKey="Debbink, K" uniqKey="Debbink K">K Debbink</name></author><author><name sortKey="Agnihothram, S" uniqKey="Agnihothram S">S Agnihothram</name></author><author><name sortKey="Gralinski, Le" uniqKey="Gralinski L">LE Gralinski</name></author><author><name sortKey="Plante, Ja" uniqKey="Plante J">JA Plante</name></author><author><name sortKey="Graham, Rl" uniqKey="Graham R">RL Graham</name></author><author><name sortKey="Scobey, T" uniqKey="Scobey T">T Scobey</name></author><author><name sortKey="Ge, Xy" uniqKey="Ge X">XY Ge</name></author><author><name sortKey="Donaldson, Ef" uniqKey="Donaldson E">EF Donaldson</name></author><author><name sortKey="Randell, Sh" uniqKey="Randell S">SH Randell</name></author><author><name sortKey="Lanzavecchia, A" uniqKey="Lanzavecchia A">A Lanzavecchia</name></author><author><name sortKey="Marasco, Wa" uniqKey="Marasco W">WA Marasco</name></author><author><name sortKey="Shi, Zl" uniqKey="Shi Z">ZL Shi</name></author><author><name sortKey="Baric, Rs" uniqKey="Baric R">RS Baric</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Meyerholz, Dk" uniqKey="Meyerholz D">DK Meyerholz</name></author><author><name sortKey="Lambertz, Am" uniqKey="Lambertz A">AM Lambertz</name></author><author><name sortKey="Mccray, Pb" uniqKey="Mccray P">PB McCray</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aeffner, F" uniqKey="Aeffner F">F Aeffner</name></author><author><name sortKey="Bolon, B" uniqKey="Bolon B">B Bolon</name></author><author><name sortKey="Davis, Ic" uniqKey="Davis I">IC Davis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dunstan, Rw" uniqKey="Dunstan R">RW Dunstan</name></author><author><name sortKey="Wharton, Ka" uniqKey="Wharton K">KA Wharton</name></author><author><name sortKey="Quigley, C" uniqKey="Quigley C">C Quigley</name></author><author><name sortKey="Lowe, A" uniqKey="Lowe A">A Lowe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Eaton, Ka" uniqKey="Eaton K">KA Eaton</name></author><author><name sortKey="Danon, Sj" uniqKey="Danon S">SJ Danon</name></author><author><name sortKey="Krakowka, S" uniqKey="Krakowka S">S Krakowka</name></author><author><name sortKey="Weisbrode, Se" uniqKey="Weisbrode S">SE Weisbrode</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Engel, Kb" uniqKey="Engel K">KB Engel</name></author><author><name sortKey="Moore, Hm" uniqKey="Moore H">HM Moore</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Renne, R" uniqKey="Renne R">R Renne</name></author><author><name sortKey="Brix, A" uniqKey="Brix A">A Brix</name></author><author><name sortKey="Harkema, J" uniqKey="Harkema J">J Harkema</name></author><author><name sortKey="Herbert, R" uniqKey="Herbert R">R Herbert</name></author><author><name sortKey="Kittel, B" uniqKey="Kittel B">B Kittel</name></author><author><name sortKey="Lewis, D" uniqKey="Lewis D">D Lewis</name></author><author><name sortKey="March, T" uniqKey="March T">T March</name></author><author><name sortKey="Nagano, K" uniqKey="Nagano K">K Nagano</name></author><author><name sortKey="Pino, M" uniqKey="Pino M">M Pino</name></author><author><name sortKey="Rittinghausen, S" uniqKey="Rittinghausen S">S Rittinghausen</name></author><author><name sortKey="Rosenbruch, M" uniqKey="Rosenbruch M">M Rosenbruch</name></author><author><name sortKey="Tellier, P" uniqKey="Tellier P">P Tellier</name></author><author><name sortKey="Wohrmann, T" uniqKey="Wohrmann T">T Wohrmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rollins, Ke" uniqKey="Rollins K">KE Rollins</name></author><author><name sortKey="Meyerholz, Dk" uniqKey="Meyerholz D">DK Meyerholz</name></author><author><name sortKey="Johnson, Gd" uniqKey="Johnson G">GD Johnson</name></author><author><name sortKey="Capparella, Ap" uniqKey="Capparella A">AP Capparella</name></author><author><name sortKey="Loew, Ss" uniqKey="Loew S">SS Loew</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Williams, Jm" uniqKey="Williams J">JM Williams</name></author><author><name sortKey="Duckworth, Ca" uniqKey="Duckworth C">CA Duckworth</name></author><author><name sortKey="Burkitt, Md" uniqKey="Burkitt M">MD Burkitt</name></author><author><name sortKey="Watson, Aj" uniqKey="Watson A">AJ Watson</name></author><author><name sortKey="Campbell, Bj" uniqKey="Campbell B">BJ Campbell</name></author><author><name sortKey="Pritchard, Dm" uniqKey="Pritchard D">DM Pritchard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Boivin, Gp" uniqKey="Boivin G">GP Boivin</name></author><author><name sortKey="Bottomley, Ma" uniqKey="Bottomley M">MA Bottomley</name></author><author><name sortKey="Schiml, Pa" uniqKey="Schiml P">PA Schiml</name></author><author><name sortKey="Goss, L" uniqKey="Goss L">L Goss</name></author><author><name sortKey="Grobe, N" uniqKey="Grobe N">N Grobe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Marquardt, N" uniqKey="Marquardt N">N Marquardt</name></author><author><name sortKey="Feja, M" uniqKey="Feja M">M Feja</name></author><author><name sortKey="Hunigen, H" uniqKey="Hunigen H">H Hunigen</name></author><author><name sortKey="Plendl, J" uniqKey="Plendl J">J Plendl</name></author><author><name sortKey="Menken, L" uniqKey="Menken L">L Menken</name></author><author><name sortKey="Fink, H" uniqKey="Fink H">H Fink</name></author><author><name sortKey="Bert, B" uniqKey="Bert B">B Bert</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Olivier, Ak" uniqKey="Olivier A">AK Olivier</name></author><author><name sortKey="Naumann, P" uniqKey="Naumann P">P Naumann</name></author><author><name sortKey="Goeken, A" uniqKey="Goeken A">A Goeken</name></author><author><name sortKey="Hochstedler, C" uniqKey="Hochstedler C">C Hochstedler</name></author><author><name sortKey="Sturm, M" uniqKey="Sturm M">M Sturm</name></author><author><name sortKey="Rodgers, Jr" uniqKey="Rodgers J">JR Rodgers</name></author><author><name sortKey="Gibson Corley, Kn" uniqKey="Gibson Corley K">KN Gibson-Corley</name></author><author><name sortKey="Meyerholz, Dk" uniqKey="Meyerholz D">DK Meyerholz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, K" uniqKey="Li K">K Li</name></author><author><name sortKey="Wohlford Lenane, Cl" uniqKey="Wohlford Lenane C">CL Wohlford-Lenane</name></author><author><name sortKey="Channappanavar, R" uniqKey="Channappanavar R">R Channappanavar</name></author><author><name sortKey="Park, Je" uniqKey="Park J">JE Park</name></author><author><name sortKey="Earnest, Jt" uniqKey="Earnest J">JT Earnest</name></author><author><name sortKey="Bair, Tb" uniqKey="Bair T">TB Bair</name></author><author><name sortKey="Bates, Am" uniqKey="Bates A">AM Bates</name></author><author><name sortKey="Brogden, Ka" uniqKey="Brogden K">KA Brogden</name></author><author><name sortKey="Flaherty, Ha" uniqKey="Flaherty H">HA Flaherty</name></author><author><name sortKey="Gallagher, T" uniqKey="Gallagher T">T Gallagher</name></author><author><name sortKey="Meyerholz, Dk" uniqKey="Meyerholz D">DK Meyerholz</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S Perlman</name></author><author><name sortKey="Mccray, Pb" uniqKey="Mccray P">PB McCray</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Meyerholz, Dk" uniqKey="Meyerholz D">DK Meyerholz</name></author><author><name sortKey="Sieren, Jc" uniqKey="Sieren J">JC Sieren</name></author><author><name sortKey="Beck, Ap" uniqKey="Beck A">AP Beck</name></author><author><name sortKey="Flaherty, Ha" uniqKey="Flaherty H">HA Flaherty</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gibson Corley, Kn" uniqKey="Gibson Corley K">KN Gibson-Corley</name></author><author><name sortKey="Hochstedler, C" uniqKey="Hochstedler C">C Hochstedler</name></author><author><name sortKey="Sturm, M" uniqKey="Sturm M">M Sturm</name></author><author><name sortKey="Rogers, J" uniqKey="Rogers J">J Rogers</name></author><author><name sortKey="Olivier, Ak" uniqKey="Olivier A">AK Olivier</name></author><author><name sortKey="Meyerholz, Dk" uniqKey="Meyerholz D">DK Meyerholz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Klopfleisch, R" uniqKey="Klopfleisch R">R Klopfleisch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ward, Jm" uniqKey="Ward J">JM Ward</name></author><author><name sortKey="Schofield, Pn" uniqKey="Schofield P">PN Schofield</name></author><author><name sortKey="Sundberg, Jp" uniqKey="Sundberg J">JP Sundberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Meyerholz, Dk" uniqKey="Meyerholz D">DK Meyerholz</name></author><author><name sortKey="Suarez, Cj" uniqKey="Suarez C">CJ Suarez</name></author><author><name sortKey="Dintis, Sm" uniqKey="Dintis S">SM Dintis</name></author><author><name sortKey="Frevert, Cw" uniqKey="Frevert C">CW Frevert</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Adissu, Ha" uniqKey="Adissu H">HA Adissu</name></author><author><name sortKey="Estabel, J" uniqKey="Estabel J">J Estabel</name></author><author><name sortKey="Sunter, D" uniqKey="Sunter D">D Sunter</name></author><author><name sortKey="Tuck, E" uniqKey="Tuck E">E Tuck</name></author><author><name sortKey="Hooks, Y" uniqKey="Hooks Y">Y Hooks</name></author><author><name sortKey="Carragher, Dm" uniqKey="Carragher D">DM Carragher</name></author><author><name sortKey="Clarke, K" uniqKey="Clarke K">K Clarke</name></author><author><name sortKey="Karp, Na" uniqKey="Karp N">NA Karp</name></author><author><name sortKey="Sanger Mouse Genetics, P" uniqKey="Sanger Mouse Genetics P">P Sanger Mouse Genetics</name></author><author><name sortKey="Newbigging, S" uniqKey="Newbigging S">S Newbigging</name></author><author><name sortKey="Jones, N" uniqKey="Jones N">N Jones</name></author><author><name sortKey="Morikawa, L" uniqKey="Morikawa L">L Morikawa</name></author><author><name sortKey="White, Jk" uniqKey="White J">JK White</name></author><author><name sortKey="Mckerlie, C" uniqKey="Mckerlie C">C McKerlie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ladiges, Warren" uniqKey="Ladiges W">Warren Ladiges</name></author><author><name sortKey="Ikeno, Yuji" uniqKey="Ikeno Y">Yuji Ikeno</name></author><author><name sortKey="Liggitt, Denny" uniqKey="Liggitt D">Denny Liggitt</name></author><author><name sortKey="Treuting, Piper M" uniqKey="Treuting P">Piper M. Treuting</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Treuting, Pm" uniqKey="Treuting P">PM Treuting</name></author><author><name sortKey="Snyder, Jm" uniqKey="Snyder J">JM Snyder</name></author><author><name sortKey="Ikeno, Y" uniqKey="Ikeno Y">Y Ikeno</name></author><author><name sortKey="Schofield, Pn" uniqKey="Schofield P">PN Schofield</name></author><author><name sortKey="Ward, Jm" uniqKey="Ward J">JM Ward</name></author><author><name sortKey="Sundberg, Jp" uniqKey="Sundberg J">JP Sundberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ward, Jm" uniqKey="Ward J">JM Ward</name></author><author><name sortKey="Youssef, Sa" uniqKey="Youssef S">SA Youssef</name></author><author><name sortKey="Treuting, Pm" uniqKey="Treuting P">PM Treuting</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cardiff, Rd" uniqKey="Cardiff R">RD Cardiff</name></author><author><name sortKey="Ward, Jm" uniqKey="Ward J">JM Ward</name></author><author><name sortKey="Barthold, Sw" uniqKey="Barthold S">SW Barthold</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wolf, Jc" uniqKey="Wolf J">JC Wolf</name></author><author><name sortKey="Wheeler, Jr" uniqKey="Wheeler J">JR Wheeler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Meyerholz, Dk" uniqKey="Meyerholz D">DK Meyerholz</name></author><author><name sortKey="Tintle, Nl" uniqKey="Tintle N">NL Tintle</name></author><author><name sortKey="Beck, Ap" uniqKey="Beck A">AP Beck</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thiesse, J" uniqKey="Thiesse J">J Thiesse</name></author><author><name sortKey="Namati, E" uniqKey="Namati E">E Namati</name></author><author><name sortKey="Sieren, Jc" uniqKey="Sieren J">JC Sieren</name></author><author><name sortKey="Smith, Ar" uniqKey="Smith A">AR Smith</name></author><author><name sortKey="Reinhardt, Jm" uniqKey="Reinhardt J">JM Reinhardt</name></author><author><name sortKey="Hoffman, Ea" uniqKey="Hoffman E">EA Hoffman</name></author><author><name sortKey="Mclennan, G" uniqKey="Mclennan G">G McLennan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Feng, Cg" uniqKey="Feng C">CG Feng</name></author><author><name sortKey="Scanga, Ca" uniqKey="Scanga C">CA Scanga</name></author><author><name sortKey="Collazo Custodio, Cm" uniqKey="Collazo Custodio C">CM Collazo-Custodio</name></author><author><name sortKey="Cheever, Aw" uniqKey="Cheever A">AW Cheever</name></author><author><name sortKey="Hieny, S" uniqKey="Hieny S">S Hieny</name></author><author><name sortKey="Caspar, P" uniqKey="Caspar P">P Caspar</name></author><author><name sortKey="Sher, A" uniqKey="Sher A">A Sher</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schulte, S" uniqKey="Schulte S">S Schulte</name></author><author><name sortKey="Sukhova, Gk" uniqKey="Sukhova G">GK Sukhova</name></author><author><name sortKey="Libby, P" uniqKey="Libby P">P Libby</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Channappanavar, R" uniqKey="Channappanavar R">R Channappanavar</name></author><author><name sortKey="Fett, C" uniqKey="Fett C">C Fett</name></author><author><name sortKey="Mack, M" uniqKey="Mack M">M Mack</name></author><author><name sortKey="Ten Eyck, Pp" uniqKey="Ten Eyck P">PP Ten Eyck</name></author><author><name sortKey="Meyerholz, Dk" uniqKey="Meyerholz D">DK Meyerholz</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S Perlman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zaki, Am" uniqKey="Zaki A">AM Zaki</name></author><author><name sortKey="Van Boheemen, S" uniqKey="Van Boheemen S">S van Boheemen</name></author><author><name sortKey="Bestebroer, Tm" uniqKey="Bestebroer T">TM Bestebroer</name></author><author><name sortKey="Osterhaus, Ad" uniqKey="Osterhaus A">AD Osterhaus</name></author><author><name sortKey="Fouchier, Ra" uniqKey="Fouchier R">RA Fouchier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Coleman, Cm" uniqKey="Coleman C">CM Coleman</name></author><author><name sortKey="Matthews, Kl" uniqKey="Matthews K">KL Matthews</name></author><author><name sortKey="Goicochea, L" uniqKey="Goicochea L">L Goicochea</name></author><author><name sortKey="Frieman, Mb" uniqKey="Frieman M">MB Frieman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Wit, E" uniqKey="De Wit E">E de Wit</name></author><author><name sortKey="Prescott, J" uniqKey="Prescott J">J Prescott</name></author><author><name sortKey="Baseler, L" uniqKey="Baseler L">L Baseler</name></author><author><name sortKey="Bushmaker, T" uniqKey="Bushmaker T">T Bushmaker</name></author><author><name sortKey="Thomas, T" uniqKey="Thomas T">T Thomas</name></author><author><name sortKey="Lackemeyer, Mg" uniqKey="Lackemeyer M">MG Lackemeyer</name></author><author><name sortKey="Martellaro, C" uniqKey="Martellaro C">C Martellaro</name></author><author><name sortKey="Milne Price, S" uniqKey="Milne Price S">S Milne-Price</name></author><author><name sortKey="Haddock, E" uniqKey="Haddock E">E Haddock</name></author><author><name sortKey="Haagmans, Bl" uniqKey="Haagmans B">BL Haagmans</name></author><author><name sortKey="Feldmann, H" uniqKey="Feldmann H">H Feldmann</name></author><author><name sortKey="Munster, Vj" uniqKey="Munster V">VJ Munster</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Wit, E" uniqKey="De Wit E">E de Wit</name></author><author><name sortKey="Rasmussen, Al" uniqKey="Rasmussen A">AL Rasmussen</name></author><author><name sortKey="Falzarano, D" uniqKey="Falzarano D">D Falzarano</name></author><author><name sortKey="Bushmaker, T" uniqKey="Bushmaker T">T Bushmaker</name></author><author><name sortKey="Feldmann, F" uniqKey="Feldmann F">F Feldmann</name></author><author><name sortKey="Brining, Dl" uniqKey="Brining D">DL Brining</name></author><author><name sortKey="Fischer, Er" uniqKey="Fischer E">ER Fischer</name></author><author><name sortKey="Martellaro, C" uniqKey="Martellaro C">C Martellaro</name></author><author><name sortKey="Okumura, A" uniqKey="Okumura A">A Okumura</name></author><author><name sortKey="Chang, J" uniqKey="Chang J">J Chang</name></author><author><name sortKey="Scott, D" uniqKey="Scott D">D Scott</name></author><author><name sortKey="Benecke, Ag" uniqKey="Benecke A">AG Benecke</name></author><author><name sortKey="Katze, Mg" uniqKey="Katze M">MG Katze</name></author><author><name sortKey="Feldmann, H" uniqKey="Feldmann H">H Feldmann</name></author><author><name sortKey="Munster, Vj" uniqKey="Munster V">VJ Munster</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Meyerholz, Dk" uniqKey="Meyerholz D">DK Meyerholz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yao, Y" uniqKey="Yao Y">Y Yao</name></author><author><name sortKey="Bao, L" uniqKey="Bao L">L Bao</name></author><author><name sortKey="Deng, W" uniqKey="Deng W">W Deng</name></author><author><name sortKey="Xu, L" uniqKey="Xu L">L Xu</name></author><author><name sortKey="Li, F" uniqKey="Li F">F Li</name></author><author><name sortKey="Lv, Q" uniqKey="Lv Q">Q Lv</name></author><author><name sortKey="Yu, P" uniqKey="Yu P">P Yu</name></author><author><name sortKey="Chen, T" uniqKey="Chen T">T Chen</name></author><author><name sortKey="Xu, Y" uniqKey="Xu Y">Y Xu</name></author><author><name sortKey="Zhu, H" uniqKey="Zhu H">H Zhu</name></author><author><name sortKey="Yuan, J" uniqKey="Yuan J">J Yuan</name></author><author><name sortKey="Gu, S" uniqKey="Gu S">S Gu</name></author><author><name sortKey="Wei, Q" uniqKey="Wei Q">Q Wei</name></author><author><name sortKey="Chen, H" uniqKey="Chen H">H Chen</name></author><author><name sortKey="Yuen, Ky" uniqKey="Yuen K">KY Yuen</name></author><author><name sortKey="Qin, C" uniqKey="Qin C">C Qin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhao, J" uniqKey="Zhao J">J Zhao</name></author><author><name sortKey="Li, K" uniqKey="Li K">K Li</name></author><author><name sortKey="Wohlford Lenane, C" uniqKey="Wohlford Lenane C">C Wohlford-Lenane</name></author><author><name sortKey="Agnihothram, Ss" uniqKey="Agnihothram S">SS Agnihothram</name></author><author><name sortKey="Fett, C" uniqKey="Fett C">C Fett</name></author><author><name sortKey="Zhao, J" uniqKey="Zhao J">J Zhao</name></author><author><name sortKey="Gale, Mj" uniqKey="Gale M">MJ Gale</name></author><author><name sortKey="Baric, Rs" uniqKey="Baric R">RS Baric</name></author><author><name sortKey="Enjuanes, L" uniqKey="Enjuanes L">L Enjuanes</name></author><author><name sortKey="Gallagher, T" uniqKey="Gallagher T">T Gallagher</name></author><author><name sortKey="Mccray, Pb" uniqKey="Mccray P">PB McCray</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S Perlman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yu, P" uniqKey="Yu P">P Yu</name></author><author><name sortKey="Xu, Y" uniqKey="Xu Y">Y Xu</name></author><author><name sortKey="Deng, W" uniqKey="Deng W">W Deng</name></author><author><name sortKey="Bao, L" uniqKey="Bao L">L Bao</name></author><author><name sortKey="Huang, L" uniqKey="Huang L">L Huang</name></author><author><name sortKey="Xu, Y" uniqKey="Xu Y">Y Xu</name></author><author><name sortKey="Yao, Y" uniqKey="Yao Y">Y Yao</name></author><author><name sortKey="Qin, C" uniqKey="Qin C">C Qin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dietert, K" uniqKey="Dietert K">K Dietert</name></author><author><name sortKey="Gutbier, B" uniqKey="Gutbier B">B Gutbier</name></author><author><name sortKey="Wienhold, Sm" uniqKey="Wienhold S">SM Wienhold</name></author><author><name sortKey="Reppe, K" uniqKey="Reppe K">K Reppe</name></author><author><name sortKey="Jiang, X" uniqKey="Jiang X">X Jiang</name></author><author><name sortKey="Yao, L" uniqKey="Yao L">L Yao</name></author><author><name sortKey="Chaput, C" uniqKey="Chaput C">C Chaput</name></author><author><name sortKey="Naujoks, J" uniqKey="Naujoks J">J Naujoks</name></author><author><name sortKey="Brack, M" uniqKey="Brack M">M Brack</name></author><author><name sortKey="Kupke, A" uniqKey="Kupke A">A Kupke</name></author><author><name sortKey="Peteranderl, C" uniqKey="Peteranderl C">C Peteranderl</name></author><author><name sortKey="Becker, S" uniqKey="Becker S">S Becker</name></author><author><name sortKey="Von Lachner, C" uniqKey="Von Lachner C">C von Lachner</name></author><author><name sortKey="Baal, N" uniqKey="Baal N">N Baal</name></author><author><name sortKey="Slevogt, H" uniqKey="Slevogt H">H Slevogt</name></author><author><name sortKey="Hocke, Ac" uniqKey="Hocke A">AC Hocke</name></author><author><name sortKey="Witzenrath, M" uniqKey="Witzenrath M">M Witzenrath</name></author><author><name sortKey="Opitz, B" uniqKey="Opitz B">B Opitz</name></author><author><name sortKey="Herold, S" uniqKey="Herold S">S Herold</name></author><author><name sortKey="Hackstein, H" uniqKey="Hackstein H">H Hackstein</name></author><author><name sortKey="Sander, Le" uniqKey="Sander L">LE Sander</name></author><author><name sortKey="Suttorp, N" uniqKey="Suttorp N">N Suttorp</name></author><author><name sortKey="Gruber, Ad" uniqKey="Gruber A">AD Gruber</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Falzarano, D" uniqKey="Falzarano D">D Falzarano</name></author><author><name sortKey="De Wit, E" uniqKey="De Wit E">E de Wit</name></author><author><name sortKey="Feldmann, F" uniqKey="Feldmann F">F Feldmann</name></author><author><name sortKey="Rasmussen, Al" uniqKey="Rasmussen A">AL Rasmussen</name></author><author><name sortKey="Okumura, A" uniqKey="Okumura A">A Okumura</name></author><author><name sortKey="Peng, X" uniqKey="Peng X">X Peng</name></author><author><name sortKey="Thomas, Mj" uniqKey="Thomas M">MJ Thomas</name></author><author><name sortKey="Van Doremalen, N" uniqKey="Van Doremalen N">N van Doremalen</name></author><author><name sortKey="Haddock, E" uniqKey="Haddock E">E Haddock</name></author><author><name sortKey="Nagy, L" uniqKey="Nagy L">L Nagy</name></author><author><name sortKey="Lacasse, R" uniqKey="Lacasse R">R LaCasse</name></author><author><name sortKey="Liu, T" uniqKey="Liu T">T Liu</name></author><author><name sortKey="Zhu, J" uniqKey="Zhu J">J Zhu</name></author><author><name sortKey="Mclellan, Js" uniqKey="Mclellan J">JS McLellan</name></author><author><name sortKey="Scott, Dp" uniqKey="Scott D">DP Scott</name></author><author><name sortKey="Katze, Mg" uniqKey="Katze M">MG Katze</name></author><author><name sortKey="Feldmann, H" uniqKey="Feldmann H">H Feldmann</name></author><author><name sortKey="Munster, Vj" uniqKey="Munster V">VJ Munster</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alsaad, Ko" uniqKey="Alsaad K">KO Alsaad</name></author><author><name sortKey="Hajeer, Ah" uniqKey="Hajeer A">AH Hajeer</name></author><author><name sortKey="Al Balwi, M" uniqKey="Al Balwi M">M Al Balwi</name></author><author><name sortKey="Al Moaiqel, M" uniqKey="Al Moaiqel M">M Al Moaiqel</name></author><author><name sortKey="Al Oudah, N" uniqKey="Al Oudah N">N Al Oudah</name></author><author><name sortKey="Al Ajlan, A" uniqKey="Al Ajlan A">A Al Ajlan</name></author><author><name sortKey="Aljohani, S" uniqKey="Aljohani S">S AlJohani</name></author><author><name sortKey="Alsolamy, S" uniqKey="Alsolamy S">S Alsolamy</name></author><author><name sortKey="Gmati, Ge" uniqKey="Gmati G">GE Gmati</name></author><author><name sortKey="Balkhy, H" uniqKey="Balkhy H">H Balkhy</name></author><author><name sortKey="Al Jahdali, Hh" uniqKey="Al Jahdali H">HH Al-Jahdali</name></author><author><name sortKey="Baharoon, Sa" uniqKey="Baharoon S">SA Baharoon</name></author><author><name sortKey="Arabi, Ym" uniqKey="Arabi Y">YM Arabi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fehr, Ar" uniqKey="Fehr A">AR Fehr</name></author><author><name sortKey="Channappanavar, R" uniqKey="Channappanavar R">R Channappanavar</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S Perlman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sweeney, Rm" uniqKey="Sweeney R">RM Sweeney</name></author><author><name sortKey="Mcauley, Df" uniqKey="Mcauley D">DF McAuley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Drew, T" uniqKey="Drew T">T Drew</name></author><author><name sortKey="Vo, Ml" uniqKey="Vo M">ML Vo</name></author><author><name sortKey="Wolfe, Jm" uniqKey="Wolfe J">JM Wolfe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Meyerholz, Dk" uniqKey="Meyerholz D">DK Meyerholz</name></author><author><name sortKey="Beck, Ap" uniqKey="Beck A">AP Beck</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Meyerholz, Dk" uniqKey="Meyerholz D">DK Meyerholz</name></author><author><name sortKey="Beck, Ap" uniqKey="Beck A">AP Beck</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gibson Corley, Kn" uniqKey="Gibson Corley K">KN Gibson-Corley</name></author><author><name sortKey="Olivier, Ak" uniqKey="Olivier A">AK Olivier</name></author><author><name sortKey="Meyerholz, Dk" uniqKey="Meyerholz D">DK Meyerholz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Meyerholz, Dk" uniqKey="Meyerholz D">DK Meyerholz</name></author><author><name sortKey="Beck, Ap" uniqKey="Beck A">AP Beck</name></author><author><name sortKey="Goeken, Ja" uniqKey="Goeken J">JA Goeken</name></author><author><name sortKey="Leidinger, Mr" uniqKey="Leidinger M">MR Leidinger</name></author><author><name sortKey="Ofori Amanfo, Gk" uniqKey="Ofori Amanfo G">GK Ofori-Amanfo</name></author><author><name sortKey="Brown, Hc" uniqKey="Brown H">HC Brown</name></author><author><name sortKey="Businga, Tr" uniqKey="Businga T">TR Businga</name></author><author><name sortKey="Stoltz, Da" uniqKey="Stoltz D">DA Stoltz</name></author><author><name sortKey="Reznikov, Lr" uniqKey="Reznikov L">LR Reznikov</name></author><author><name sortKey="Flaherty, Ha" uniqKey="Flaherty H">HA Flaherty</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vergara Alert, J" uniqKey="Vergara Alert J">J Vergara-Alert</name></author><author><name sortKey="Vidal, E" uniqKey="Vidal E">E Vidal</name></author><author><name sortKey="Bensaid, A" uniqKey="Bensaid A">A Bensaid</name></author><author><name sortKey="Segales, J" uniqKey="Segales J">J Segales</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Haagmans, Bl" uniqKey="Haagmans B">BL Haagmans</name></author><author><name sortKey="Van Den Brand, Jm" uniqKey="Van Den Brand J">JM van den Brand</name></author><author><name sortKey="Provacia, Lb" uniqKey="Provacia L">LB Provacia</name></author><author><name sortKey="Raj, Vs" uniqKey="Raj V">VS Raj</name></author><author><name sortKey="Stittelaar, Kj" uniqKey="Stittelaar K">KJ Stittelaar</name></author><author><name sortKey="Getu, S" uniqKey="Getu S">S Getu</name></author><author><name sortKey="De Waal, L" uniqKey="De Waal L">L de Waal</name></author><author><name sortKey="Bestebroer, Tm" uniqKey="Bestebroer T">TM Bestebroer</name></author><author><name sortKey="Van Amerongen, G" uniqKey="Van Amerongen G">G van Amerongen</name></author><author><name sortKey="Verjans, Gm" uniqKey="Verjans G">GM Verjans</name></author><author><name sortKey="Fouchier, Ra" uniqKey="Fouchier R">RA Fouchier</name></author><author><name sortKey="Smits, Sl" uniqKey="Smits S">SL Smits</name></author><author><name sortKey="Kuiken, T" uniqKey="Kuiken T">T Kuiken</name></author><author><name sortKey="Osterhaus, Ad" uniqKey="Osterhaus A">AD Osterhaus</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vergara Alert, J" uniqKey="Vergara Alert J">J Vergara-Alert</name></author><author><name sortKey="Van Den Brand, Jm" uniqKey="Van Den Brand J">JM van den Brand</name></author><author><name sortKey="Widagdo, W" uniqKey="Widagdo W">W Widagdo</name></author><author><name sortKey="Munoz, Mt" uniqKey="Munoz M">MT Munoz</name></author><author><name sortKey="Raj, S" uniqKey="Raj S">S Raj</name></author><author><name sortKey="Schipper, D" uniqKey="Schipper D">D Schipper</name></author><author><name sortKey="Solanes, D" uniqKey="Solanes D">D Solanes</name></author><author><name sortKey="Cordon, I" uniqKey="Cordon I">I Cordon</name></author><author><name sortKey="Bensaid, A" uniqKey="Bensaid A">A Bensaid</name></author><author><name sortKey="Haagmans, Bl" uniqKey="Haagmans B">BL Haagmans</name></author><author><name sortKey="Segales, J" uniqKey="Segales J">J Segales</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Widagdo, W" uniqKey="Widagdo W">W Widagdo</name></author><author><name sortKey="Raj, Vs" uniqKey="Raj V">VS Raj</name></author><author><name sortKey="Schipper, D" uniqKey="Schipper D">D Schipper</name></author><author><name sortKey="Kolijn, K" uniqKey="Kolijn K">K Kolijn</name></author><author><name sortKey="Van Leenders, G" uniqKey="Van Leenders G">G van Leenders</name></author><author><name sortKey="Bosch, Bj" uniqKey="Bosch B">BJ Bosch</name></author><author><name sortKey="Bensaid, A" uniqKey="Bensaid A">A Bensaid</name></author><author><name sortKey="Segales, J" uniqKey="Segales J">J Segales</name></author><author><name sortKey="Baumgartner, W" uniqKey="Baumgartner W">W Baumgartner</name></author><author><name sortKey="Osterhaus, A" uniqKey="Osterhaus A">A Osterhaus</name></author><author><name sortKey="Koopmans, Mp" uniqKey="Koopmans M">MP Koopmans</name></author><author><name sortKey="Van Den Brand, Jma" uniqKey="Van Den Brand J">JMA van den Brand</name></author><author><name sortKey="Haagmans, Bl" uniqKey="Haagmans B">BL Haagmans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Janardhan, Ks" uniqKey="Janardhan K">KS Janardhan</name></author><author><name sortKey="Jensen, H" uniqKey="Jensen H">H Jensen</name></author><author><name sortKey="Clayton, Np" uniqKey="Clayton N">NP Clayton</name></author><author><name sortKey="Herbert, Ra" uniqKey="Herbert R">RA Herbert</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, Sw" uniqKey="Kim S">SW Kim</name></author><author><name sortKey="Roh, J" uniqKey="Roh J">J Roh</name></author><author><name sortKey="Park, Cs" uniqKey="Park C">CS Park</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ramos Vara, Ja" uniqKey="Ramos Vara J">JA Ramos-Vara</name></author><author><name sortKey="Miller, Ma" uniqKey="Miller M">MA Miller</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ward, Jm" uniqKey="Ward J">JM Ward</name></author><author><name sortKey="Rehg, Je" uniqKey="Rehg J">JE Rehg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aeffner, F" uniqKey="Aeffner F">F Aeffner</name></author><author><name sortKey="Adissu, Ha" uniqKey="Adissu H">HA Adissu</name></author><author><name sortKey="Boyle, Mc" uniqKey="Boyle M">MC Boyle</name></author><author><name sortKey="Cardiff, Rd" uniqKey="Cardiff R">RD Cardiff</name></author><author><name sortKey="Hagendorn, E" uniqKey="Hagendorn E">E Hagendorn</name></author><author><name sortKey="Hoenerhoff, Mj" uniqKey="Hoenerhoff M">MJ Hoenerhoff</name></author><author><name sortKey="Klopfleisch, R" uniqKey="Klopfleisch R">R Klopfleisch</name></author><author><name sortKey="Newbigging, S" uniqKey="Newbigging S">S Newbigging</name></author><author><name sortKey="Schaudien, D" uniqKey="Schaudien D">D Schaudien</name></author><author><name sortKey="Turner, O" uniqKey="Turner O">O Turner</name></author><author><name sortKey="Wilson, K" uniqKey="Wilson K">K Wilson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barisoni, L" uniqKey="Barisoni L">L Barisoni</name></author><author><name sortKey="Gimpel, C" uniqKey="Gimpel C">C Gimpel</name></author><author><name sortKey="Kain, R" uniqKey="Kain R">R Kain</name></author><author><name sortKey="Laurinavicius, A" uniqKey="Laurinavicius A">A Laurinavicius</name></author><author><name sortKey="Bueno, G" uniqKey="Bueno G">G Bueno</name></author><author><name sortKey="Zeng, C" uniqKey="Zeng C">C Zeng</name></author><author><name sortKey="Liu, Z" uniqKey="Liu Z">Z Liu</name></author><author><name sortKey="Schaefer, F" uniqKey="Schaefer F">F Schaefer</name></author><author><name sortKey="Kretzler, M" uniqKey="Kretzler M">M Kretzler</name></author><author><name sortKey="Holzman, Lb" uniqKey="Holzman L">LB Holzman</name></author><author><name sortKey="Hewitt, Sm" uniqKey="Hewitt S">SM Hewitt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Colling, Richard" uniqKey="Colling R">Richard Colling</name></author><author><name sortKey="Pitman, Helen" uniqKey="Pitman H">Helen Pitman</name></author><author><name sortKey="Oien, Karin" uniqKey="Oien K">Karin Oien</name></author><author><name sortKey="Rajpoot, Nasir" uniqKey="Rajpoot N">Nasir Rajpoot</name></author><author><name sortKey="Macklin, Philip" uniqKey="Macklin P">Philip Macklin</name></author><author><name sortKey="Bachtiar, Velicia" uniqKey="Bachtiar V">Velicia Bachtiar</name></author><author><name sortKey="Booth, Richard" uniqKey="Booth R">Richard Booth</name></author><author><name sortKey="Bryant, Alyson" uniqKey="Bryant A">Alyson Bryant</name></author><author><name sortKey="Bull, Joshua" uniqKey="Bull J">Joshua Bull</name></author><author><name sortKey="Bury, Jonathan" uniqKey="Bury J">Jonathan Bury</name></author><author><name sortKey="Carragher, Fiona" uniqKey="Carragher F">Fiona Carragher</name></author><author><name sortKey="Colling, Richard" uniqKey="Colling R">Richard Colling</name></author><author><name sortKey="Collins, Graeme" uniqKey="Collins G">Graeme Collins</name></author><author><name sortKey="Craig, Clare" uniqKey="Craig C">Clare Craig</name></author><author><name sortKey="Da Silva, Maria Freitas" uniqKey="Da Silva M">Maria Freitas da Silva</name></author><author><name sortKey="Gosling, Daniel" uniqKey="Gosling D">Daniel Gosling</name></author><author><name sortKey="Jacobs, Jaco" uniqKey="Jacobs J">Jaco Jacobs</name></author><author><name sortKey="Kajland Ilen, Lena" uniqKey="Kajland Ilen L">Lena Kajland‐Wilén</name></author><author><name sortKey="Karling, Johanna" uniqKey="Karling J">Johanna Karling</name></author><author><name sortKey="Lawler, Darragh" uniqKey="Lawler D">Darragh Lawler</name></author><author><name sortKey="Lee, Stephen" uniqKey="Lee S">Stephen Lee</name></author><author><name sortKey="Macklin, Philip" uniqKey="Macklin P">Philip Macklin</name></author><author><name sortKey="Miller, Keith" uniqKey="Miller K">Keith Miller</name></author><author><name sortKey="Mozolowski, Guy" uniqKey="Mozolowski G">Guy Mozolowski</name></author><author><name sortKey="Nicholson, Richard" uniqKey="Nicholson R">Richard Nicholson</name></author><author><name sortKey="O Connor, Daniel" uniqKey="O Connor D">Daniel O'Connor</name></author><author><name sortKey="Rahbek, Mikkel" uniqKey="Rahbek M">Mikkel Rahbek</name></author><author><name sortKey="Rajpoot, Nasir" uniqKey="Rajpoot N">Nasir Rajpoot</name></author><author><name sortKey="Sumner, Alan" uniqKey="Sumner A">Alan Sumner</name></author><author><name sortKey="Vossen, Dirk" uniqKey="Vossen D">Dirk Vossen</name></author><author><name sortKey="White, Kieron" uniqKey="White K">Kieron White</name></author><author><name sortKey="Wing, Charlotte" uniqKey="Wing C">Charlotte Wing</name></author><author><name sortKey="Wright, Corrina" uniqKey="Wright C">Corrina Wright</name></author><author><name sortKey="Snead, David" uniqKey="Snead D">David Snead</name></author><author><name sortKey="Sackville, Tony" uniqKey="Sackville T">Tony Sackville</name></author><author><name sortKey="Verrill, Clare" uniqKey="Verrill C">Clare Verrill</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Niazi, Mkk" uniqKey="Niazi M">MKK Niazi</name></author><author><name sortKey="Parwani, Av" uniqKey="Parwani A">AV Parwani</name></author><author><name sortKey="Gurcan, Mn" uniqKey="Gurcan M">MN Gurcan</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list></list><tree></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000548 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000548 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= MersV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:7123785
|texte= Histopathologic Evaluation and Scoring of Viral Lung Infection
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:31883098" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a MersV1
| This area was generated with Dilib version V0.6.33. |  |