Replicative virus shedding in the respiratory tract of patients with Middle East respiratory syndrome coronavirus infection
Identifieur interne : 000830 ( Main/Curation ); précédent : 000829; suivant : 000831Replicative virus shedding in the respiratory tract of patients with Middle East respiratory syndrome coronavirus infection
Auteurs : Wan Beom Park [Corée du Sud] ; Leo L. M. Poon [République populaire de Chine] ; Su-Jin Choi [Corée du Sud] ; Pyoeng Gyun Choe [Corée du Sud] ; Kyoung-Ho Song [Corée du Sud] ; Ji Hwan Bang [Corée du Sud] ; Eu Suk Kim [Corée du Sud] ; Hong Bin Kim [Corée du Sud] ; Sang Won Park [Corée du Sud] ; Nam Joong Kim [Corée du Sud] ; Malik Peiris [République populaire de Chine] ; Myoung-Don Oh [Corée du Sud]Source :
- International Journal of Infectious Diseases [ 1201-9712 ] ; 2018.
Descripteurs français
- KwdFr :
- Appareil respiratoire (physiopathologie), Appareil respiratoire (virologie), Coronavirus du syndrome respiratoire du Moyen-Orient (isolement et purification), Excrétion virale, Expectoration (virologie), Humains, Infections à coronavirus (physiopathologie), Infections à coronavirus (virologie), Réaction de polymérisation en chaine en temps réel, Réplication virale, Transcription inverse.
- MESH :
- isolement et purification : Coronavirus du syndrome respiratoire du Moyen-Orient.
- physiopathologie : Appareil respiratoire, Infections à coronavirus.
- virologie : Appareil respiratoire, Expectoration, Infections à coronavirus.
- Excrétion virale, Humains, Réaction de polymérisation en chaine en temps réel, Réplication virale, Transcription inverse.
English descriptors
- KwdEn :
- Coronavirus Infections (physiopathology), Coronavirus Infections (virology), Humans, Middle East Respiratory Syndrome Coronavirus (isolation & purification), Real-Time Polymerase Chain Reaction, Respiratory System (physiopathology), Respiratory System (virology), Reverse Transcription, Sputum (virology), Virus Replication, Virus Shedding.
- MESH :
- isolation & purification : Middle East Respiratory Syndrome Coronavirus.
- physiopathology : Coronavirus Infections, Respiratory System.
- virology : Coronavirus Infections, Respiratory System, Sputum.
- Humans, Real-Time Polymerase Chain Reaction, Reverse Transcription, Virus Replication, Virus Shedding.
Abstract
Middle East respiratory syndrome coronavirus (MERS-CoV) sub-genomic mRNAs indicates that the virus is replicative. Sub-genomic mRNA was detected in lower respiratory tract specimens for up to 4 weeks after symptoms developed. In upper respiratory tract specimens, the detection of sub-genomic mRNA and genomic RNA did not correlate.
Url:
DOI: 10.1016/j.ijid.2018.05.003
PubMed: 29753119
PubMed Central: 7110884
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PMC:7110884Le document en format XML
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<term>Middle East Respiratory Syndrome Coronavirus (isolation & purification)</term>
<term>Real-Time Polymerase Chain Reaction</term>
<term>Respiratory System (physiopathology)</term>
<term>Respiratory System (virology)</term>
<term>Reverse Transcription</term>
<term>Sputum (virology)</term>
<term>Virus Replication</term>
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<term>Appareil respiratoire (virologie)</term>
<term>Coronavirus du syndrome respiratoire du Moyen-Orient (isolement et purification)</term>
<term>Excrétion virale</term>
<term>Expectoration (virologie)</term>
<term>Humains</term>
<term>Infections à coronavirus (physiopathologie)</term>
<term>Infections à coronavirus (virologie)</term>
<term>Réaction de polymérisation en chaine en temps réel</term>
<term>Réplication virale</term>
<term>Transcription inverse</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Middle East Respiratory Syndrome Coronavirus</term>
</keywords>
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<keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Appareil respiratoire</term>
<term>Infections à coronavirus</term>
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<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Respiratory System</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Appareil respiratoire</term>
<term>Expectoration</term>
<term>Infections à coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Respiratory System</term>
<term>Sputum</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Humans</term>
<term>Real-Time Polymerase Chain Reaction</term>
<term>Reverse Transcription</term>
<term>Virus Replication</term>
<term>Virus Shedding</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Excrétion virale</term>
<term>Humains</term>
<term>Réaction de polymérisation en chaine en temps réel</term>
<term>Réplication virale</term>
<term>Transcription inverse</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><title>Highlights</title>
<p><list list-type="simple" id="lis0005"><list-item id="lsti0005"><label>•</label>
<p id="par0005">Middle East respiratory syndrome coronavirus (MERS-CoV) sub-genomic mRNAs indicates that the virus is replicative.</p>
</list-item>
<list-item id="lsti0010"><label>•</label>
<p id="par0010">Sub-genomic mRNA was detected in lower respiratory tract specimens for up to 4 weeks after symptoms developed.</p>
</list-item>
<list-item id="lsti0015"><label>•</label>
<p id="par0015">In upper respiratory tract specimens, the detection of sub-genomic mRNA and genomic RNA did not correlate.</p>
</list-item>
</list>
</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Corman, V M" uniqKey="Corman V">V.M. Corman</name>
</author>
<author><name sortKey="Albarrak, A M" uniqKey="Albarrak A">A.M. Albarrak</name>
</author>
<author><name sortKey="Omrani, A S" uniqKey="Omrani A">A.S. Omrani</name>
</author>
<author><name sortKey="Albarrak, M M" uniqKey="Albarrak M">M.M. Albarrak</name>
</author>
<author><name sortKey="Farah, M E" uniqKey="Farah M">M.E. Farah</name>
</author>
<author><name sortKey="Almasri, M" uniqKey="Almasri M">M. Almasri</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Memish, Z A" uniqKey="Memish Z">Z.A. Memish</name>
</author>
<author><name sortKey="Assiri, A M" uniqKey="Assiri A">A.M. Assiri</name>
</author>
<author><name sortKey="Al Tawfiq, J A" uniqKey="Al Tawfiq J">J.A. Al-Tawfiq</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Min, C K" uniqKey="Min C">C.K. Min</name>
</author>
<author><name sortKey="Cheon, S" uniqKey="Cheon S">S. Cheon</name>
</author>
<author><name sortKey="Ha, N Y" uniqKey="Ha N">N.Y. Ha</name>
</author>
<author><name sortKey="Sohn, K M" uniqKey="Sohn K">K.M. Sohn</name>
</author>
<author><name sortKey="Kim, Y" uniqKey="Kim Y">Y. Kim</name>
</author>
<author><name sortKey="Aigerim, A" uniqKey="Aigerim A">A. Aigerim</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Oh, M D" uniqKey="Oh M">M.D. Oh</name>
</author>
<author><name sortKey="Park, W B" uniqKey="Park W">W.B. Park</name>
</author>
<author><name sortKey="Choe, P G" uniqKey="Choe P">P.G. Choe</name>
</author>
<author><name sortKey="Choi, S J" uniqKey="Choi S">S.J. Choi</name>
</author>
<author><name sortKey="Kim, J I" uniqKey="Kim J">J.I. Kim</name>
</author>
<author><name sortKey="Chae, J" uniqKey="Chae J">J. Chae</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Park, W B" uniqKey="Park W">W.B. Park</name>
</author>
<author><name sortKey="Perera, R A" uniqKey="Perera R">R.A. Perera</name>
</author>
<author><name sortKey="Choe, P G" uniqKey="Choe P">P.G. Choe</name>
</author>
<author><name sortKey="Lau, E H" uniqKey="Lau E">E.H. Lau</name>
</author>
<author><name sortKey="Choi, S J" uniqKey="Choi S">S.J. Choi</name>
</author>
<author><name sortKey="Chun, J Y" uniqKey="Chun J">J.Y. Chun</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sawicki, S G" uniqKey="Sawicki S">S.G. Sawicki</name>
</author>
<author><name sortKey="Sawicki, D L" uniqKey="Sawicki D">D.L. Sawicki</name>
</author>
<author><name sortKey="Siddell, S G" uniqKey="Siddell S">S.G. Siddell</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Who" uniqKey="Who">WHO</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name>
</author>
<author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name>
</author>
<author><name sortKey="Fan, R Y" uniqKey="Fan R">R.Y. Fan</name>
</author>
<author><name sortKey="Lau, C C" uniqKey="Lau C">C.C. Lau</name>
</author>
<author><name sortKey="Wong, E Y" uniqKey="Wong E">E.Y. Wong</name>
</author>
<author><name sortKey="Joseph, S" uniqKey="Joseph S">S. Joseph</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
</record>
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