A Novel Coronavirus from Patients with Pneumonia in China, 2019
Identifieur interne : 000309 ( Main/Curation ); précédent : 000308; suivant : 000310A Novel Coronavirus from Patients with Pneumonia in China, 2019
Auteurs : Na Zhu ; Dingyu Zhang ; Wenling Wang ; Xingwang Li ; Bo Yang ; Jingdong Song ; Xiang Zhao ; Baoying Huang ; Weifeng Shi ; Roujian Lu ; Peihua Niu ; Faxian Zhan ; Xuejun Ma ; Dayan Wang ; Wenbo Xu ; Guizhen Wu ; George F. Gao ; Wenjie TanSource :
- The New England Journal of Medicine [ 0028-4793 ] ; 2020.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Appareil respiratoire (anatomopathologie), Appareil respiratoire (virologie), Cellules cultivées, Cellules épithéliales (anatomopathologie), Cellules épithéliales (virologie), Chine, Femelle, Génome viral, Humains, Infections à coronavirus (anatomopathologie), Infections à coronavirus (imagerie diagnostique), Infections à coronavirus (virologie), Liquide de lavage bronchoalvéolaire (virologie), Microscopie électronique à transmission, Mâle, Phylogénie, Pneumopathie virale (anatomopathologie), Pneumopathie virale (imagerie diagnostique), Pneumopathie virale (virologie), Poumon (anatomopathologie), Poumon (imagerie diagnostique), Poumon (virologie), Radiographie thoracique.
- MESH :
- anatomopathologie : Appareil respiratoire, Cellules épithéliales, Infections à coronavirus, Pneumopathie virale, Poumon.
- imagerie diagnostique : Infections à coronavirus, Pneumopathie virale, Poumon.
- virologie : Appareil respiratoire, Cellules épithéliales, Infections à coronavirus, Liquide de lavage bronchoalvéolaire, Pneumopathie virale, Poumon.
- Adulte, Adulte d'âge moyen, Cellules cultivées, Chine, Femelle, Génome viral, Humains, Microscopie électronique à transmission, Mâle, Phylogénie, Radiographie thoracique.
- Wicri :
- geographic : République populaire de Chine.
English descriptors
- KwdEn :
- Adult, Betacoronavirus (genetics), Betacoronavirus (isolation & purification), Betacoronavirus (ultrastructure), Bronchoalveolar Lavage Fluid (virology), Cells, Cultured, China, Coronavirus Infections (diagnostic imaging), Coronavirus Infections (pathology), Coronavirus Infections (virology), Epithelial Cells (pathology), Epithelial Cells (virology), Female, Genome, Viral, Humans, Lung (diagnostic imaging), Lung (pathology), Lung (virology), Male, Microscopy, Electron, Transmission, Middle Aged, Phylogeny, Pneumonia, Viral (diagnostic imaging), Pneumonia, Viral (pathology), Pneumonia, Viral (virology), Radiography, Thoracic, Respiratory System (pathology), Respiratory System (virology).
- MESH :
- geographic : China.
- diagnostic imaging : Coronavirus Infections, Lung, Pneumonia, Viral.
- genetics : Betacoronavirus.
- isolation & purification : Betacoronavirus.
- pathology : Coronavirus Infections, Epithelial Cells, Lung, Pneumonia, Viral, Respiratory System.
- ultrastructure : Betacoronavirus.
- virology : Bronchoalveolar Lavage Fluid, Coronavirus Infections, Epithelial Cells, Lung, Pneumonia, Viral, Respiratory System.
- Adult, Cells, Cultured, Female, Genome, Viral, Humans, Male, Microscopy, Electron, Transmission, Middle Aged, Phylogeny, Radiography, Thoracic.
Abstract
In December 2019, a cluster of patients with pneumonia of unknown cause was linked to a seafood wholesale market in Wuhan, China. A previously unknown betacoronavirus was discovered through the use of unbiased sequencing in samples from patients with pneumonia. Human airway epithelial cells were used to isolate a novel coronavirus, named 2019-nCoV, which formed a clade within the subgenus sarbecovirus, Orthocoronavirinae subfamily. Different from both MERS-CoV and SARS-CoV, 2019-nCoV is the seventh member of the family of coronaviruses that infect humans. Enhanced surveillance and further investigation are ongoing. (Funded by the National Key Research and Development Program of China and the National Major Project for Control and Prevention of Infectious Disease in China.)
Url:
DOI: 10.1056/NEJMoa2001017
PubMed: 31978945
PubMed Central: 7092803
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PMC:7092803Le document en format XML
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<term>Pneumopathie virale</term>
<term>Poumon</term>
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<term>Pneumonia, Viral</term>
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<front><div type="abstract" xml:lang="en"><title>Summary</title>
<p>In December 2019, a cluster of patients with pneumonia of unknown cause was linked to a seafood wholesale market in Wuhan, China. A previously unknown betacoronavirus was discovered through the use of unbiased sequencing in samples from patients with pneumonia. Human airway epithelial cells were used to isolate a novel coronavirus, named 2019-nCoV, which formed a clade within the subgenus sarbecovirus, Orthocoronavirinae subfamily. Different from both MERS-CoV and SARS-CoV, 2019-nCoV is the seventh member of the family of coronaviruses that infect humans. Enhanced surveillance and further investigation are ongoing. (Funded by the National Key Research and Development Program of China and the National Major Project for Control and Prevention of Infectious Disease in China.)</p>
</div>
</front>
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