Metal Complex Derivatives of Peptide Nucleic Acids (PNA)
Identifieur interne : 000431 ( Istex/Curation ); précédent : 000430; suivant : 000432Metal Complex Derivatives of Peptide Nucleic Acids (PNA)
Auteurs : Roland Kr Mer [Allemagne] ; Andriy Mokhir [Allemagne]Source :
- Metal Ions in Life Sciences [ 1559-0836 ]
Abstract
Abstract: Peptide nucleic acid (PNA) is a non-cyclic pseudopeptide-nucleic acid structural mimic with promising applications within diagnostics and drug discovery. This review focuses on metal complex derivatives of PNA. Metal ions and their complexes display unique physical and chemical properties and offer the opportunity to introduce new labels and probes for bioanalytical and diagnostic applications of PNA, but also to modulate or to introduce new (for example catalytic) functions and biological activities.
Url:
DOI: 10.1007/978-94-007-2172-2_12
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