Condylomata acuminata in children: Frequent association with human papillomaviruses responsible for cutaneous warts
Identifieur interne : 001653 ( Istex/Corpus ); précédent : 001652; suivant : 001654Condylomata acuminata in children: Frequent association with human papillomaviruses responsible for cutaneous warts
Auteurs : Slavomir Obalek ; Stéfania Jablonska ; Michel Favre ; Leszek Walczak ; Gérard OrthSource :
- Journal of the American Academy of Dermatology [ 0190-9622 ] ; 1990.
English descriptors
- Teeft :
- Acuminata, American academy, Anal, Anal condylomata, Anal wart, Anogenital, Anogenital area, Anogenital condylomata, Anogenital warts, Blot hybridization, Cervical, Cervical condylomata, Cervix, Common hand warts, Common warts, Condyloma, Condylomata acuminata, Cutaneous, Cutaneous warts, External condylomata, First week, Genital, Genital papillomaviruses, Genital warts, Histologic, Histologic features, Human papillomavirus, Hybridization, Lesion, Obstet gynecol, Papillomavirus, Papillomaviruses, Penis, Perianal, Sexual abuse, Skin warts, Viral, Virologic, Virologic studies, Vulva, Vulvar, Vulvar anal, Vulvar condylomata, Wart.
Abstract
To identify the papillomavirus types associated with condylomata acuminata in children and to evaluate their mode of transmission, we studied 32 children with anogenital warts. External condylomata were found in 12 of their mothers and in 10 of their fathers. Ten mothers, including two without external lesions, had cervical condylomata. Blot hybridization studies disclosed a genital human papillomavirus (HPV) in 14 of 27 children (HPV-6 in 12 and HPV-11 in two) and in 8 of 14 patients (HPV-6 in all). HPV-6 was found in another child by the polymerase chain reaction technique. Infection occurred most likely at birth or from nonsexual contact, but sexual abuse could not be excluded in one 11 -year-old girl. Cutaneous HPV-2 was found in seven children and as yet uncharacterized papillomaviruses were found in two children. Three mothers of HPV-2-infected children had common hand warts, and two children had subungual warts. This study shows the frequent nonsexual transmission of genital papillomaviruses in children and the unexpectedly high association of children's condylomata with papillomaviruses responsible for skin warts, possibly transmitted by heteroinoculation or autoinoculation.
Url:
DOI: 10.1016/0190-9622(90)70200-2
Links to Exploration step
ISTEX:A151382182153FE88A682DAAECB76D4645617F67Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Condylomata acuminata in children: Frequent association with human papillomaviruses responsible for cutaneous warts</title><author><name sortKey="Obalek, Slavomir" sort="Obalek, Slavomir" uniqKey="Obalek S" first="Slavomir" last="Obalek">Slavomir Obalek</name><affiliation><mods:affiliation>From the Department of Dermatology, Warsaw School of Medicine, Warsaw, Poland</mods:affiliation></affiliation><affiliation><mods:affiliation>From the Unité des Papillomavirus, Unité INSERM 190, Institut Pasteur, Paris, France</mods:affiliation></affiliation><affiliation><mods:affiliation>*Recipient of a fellowship from the Fondation pour la Recherche Médicale.</mods:affiliation></affiliation></author><author><name sortKey="Jablonska, Stefania" sort="Jablonska, Stefania" uniqKey="Jablonska S" first="Stéfania" last="Jablonska">Stéfania Jablonska</name><affiliation><mods:affiliation>From the Department of Dermatology, Warsaw School of Medicine, Warsaw, Poland</mods:affiliation></affiliation></author><author><name sortKey="Favre, Michel" sort="Favre, Michel" uniqKey="Favre M" first="Michel" last="Favre">Michel Favre</name><affiliation><mods:affiliation>From the Unité des Papillomavirus, Unité INSERM 190, Institut Pasteur, Paris, France</mods:affiliation></affiliation></author><author><name sortKey="Walczak, Leszek" sort="Walczak, Leszek" uniqKey="Walczak L" first="Leszek" last="Walczak">Leszek Walczak</name><affiliation><mods:affiliation>From the Department of Dermatology, Warsaw School of Medicine, Warsaw, Poland</mods:affiliation></affiliation></author><author><name sortKey="Orth, Gerard" sort="Orth, Gerard" uniqKey="Orth G" first="Gérard" last="Orth">Gérard Orth</name><affiliation><mods:affiliation>From the Unité des Papillomavirus, Unité INSERM 190, Institut Pasteur, Paris, France</mods:affiliation></affiliation><affiliation><mods:affiliation>Reprint requests: Gérard Orth, DVM, Unité des Papillomavirus, Institut Pasteur, 25, rue du Docteur Roux, 75724 Paris Cedex 15, France.</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:A151382182153FE88A682DAAECB76D4645617F67</idno><date when="1990" year="1990">1990</date><idno type="doi">10.1016/0190-9622(90)70200-2</idno><idno type="url">https://api.istex.fr/ark:/67375/6H6-0WPZMNCK-G/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">001653</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001653</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Condylomata acuminata in children: Frequent association with human papillomaviruses responsible for cutaneous warts</title><author><name sortKey="Obalek, Slavomir" sort="Obalek, Slavomir" uniqKey="Obalek S" first="Slavomir" last="Obalek">Slavomir Obalek</name><affiliation><mods:affiliation>From the Department of Dermatology, Warsaw School of Medicine, Warsaw, Poland</mods:affiliation></affiliation><affiliation><mods:affiliation>From the Unité des Papillomavirus, Unité INSERM 190, Institut Pasteur, Paris, France</mods:affiliation></affiliation><affiliation><mods:affiliation>*Recipient of a fellowship from the Fondation pour la Recherche Médicale.</mods:affiliation></affiliation></author><author><name sortKey="Jablonska, Stefania" sort="Jablonska, Stefania" uniqKey="Jablonska S" first="Stéfania" last="Jablonska">Stéfania Jablonska</name><affiliation><mods:affiliation>From the Department of Dermatology, Warsaw School of Medicine, Warsaw, Poland</mods:affiliation></affiliation></author><author><name sortKey="Favre, Michel" sort="Favre, Michel" uniqKey="Favre M" first="Michel" last="Favre">Michel Favre</name><affiliation><mods:affiliation>From the Unité des Papillomavirus, Unité INSERM 190, Institut Pasteur, Paris, France</mods:affiliation></affiliation></author><author><name sortKey="Walczak, Leszek" sort="Walczak, Leszek" uniqKey="Walczak L" first="Leszek" last="Walczak">Leszek Walczak</name><affiliation><mods:affiliation>From the Department of Dermatology, Warsaw School of Medicine, Warsaw, Poland</mods:affiliation></affiliation></author><author><name sortKey="Orth, Gerard" sort="Orth, Gerard" uniqKey="Orth G" first="Gérard" last="Orth">Gérard Orth</name><affiliation><mods:affiliation>From the Unité des Papillomavirus, Unité INSERM 190, Institut Pasteur, Paris, France</mods:affiliation></affiliation><affiliation><mods:affiliation>Reprint requests: Gérard Orth, DVM, Unité des Papillomavirus, Institut Pasteur, 25, rue du Docteur Roux, 75724 Paris Cedex 15, France.</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of the American Academy of Dermatology</title><title level="j" type="abbrev">YMJD</title><idno type="ISSN">0190-9622</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1990">1990</date><biblScope unit="volume">23</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="supplement">P1</biblScope><biblScope unit="page" from="205">205</biblScope><biblScope unit="page" to="213">213</biblScope></imprint><idno type="ISSN">0190-9622</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0190-9622</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Acuminata</term><term>American academy</term><term>Anal</term><term>Anal condylomata</term><term>Anal wart</term><term>Anogenital</term><term>Anogenital area</term><term>Anogenital condylomata</term><term>Anogenital warts</term><term>Blot hybridization</term><term>Cervical</term><term>Cervical condylomata</term><term>Cervix</term><term>Common hand warts</term><term>Common warts</term><term>Condyloma</term><term>Condylomata acuminata</term><term>Cutaneous</term><term>Cutaneous warts</term><term>External condylomata</term><term>First week</term><term>Genital</term><term>Genital papillomaviruses</term><term>Genital warts</term><term>Histologic</term><term>Histologic features</term><term>Human papillomavirus</term><term>Hybridization</term><term>Lesion</term><term>Obstet gynecol</term><term>Papillomavirus</term><term>Papillomaviruses</term><term>Penis</term><term>Perianal</term><term>Sexual abuse</term><term>Skin warts</term><term>Viral</term><term>Virologic</term><term>Virologic studies</term><term>Vulva</term><term>Vulvar</term><term>Vulvar anal</term><term>Vulvar condylomata</term><term>Wart</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract">To identify the papillomavirus types associated with condylomata acuminata in children and to evaluate their mode of transmission, we studied 32 children with anogenital warts. External condylomata were found in 12 of their mothers and in 10 of their fathers. Ten mothers, including two without external lesions, had cervical condylomata. Blot hybridization studies disclosed a genital human papillomavirus (HPV) in 14 of 27 children (HPV-6 in 12 and HPV-11 in two) and in 8 of 14 patients (HPV-6 in all). HPV-6 was found in another child by the polymerase chain reaction technique. Infection occurred most likely at birth or from nonsexual contact, but sexual abuse could not be excluded in one 11 -year-old girl. Cutaneous HPV-2 was found in seven children and as yet uncharacterized papillomaviruses were found in two children. Three mothers of HPV-2-infected children had common hand warts, and two children had subungual warts. This study shows the frequent nonsexual transmission of genital papillomaviruses in children and the unexpectedly high association of children's condylomata with papillomaviruses responsible for skin warts, possibly transmitted by heteroinoculation or autoinoculation.</div></front></TEI><istex><corpusName>elsevier</corpusName><keywords><teeft><json:string>condyloma</json:string><json:string>anal</json:string><json:string>genital</json:string><json:string>vulvar</json:string><json:string>acuminata</json:string><json:string>anogenital</json:string><json:string>condylomata acuminata</json:string><json:string>papillomavirus</json:string><json:string>cervix</json:string><json:string>cervical</json:string><json:string>vulva</json:string><json:string>hybridization</json:string><json:string>cutaneous</json:string><json:string>papillomaviruses</json:string><json:string>histologic</json:string><json:string>vulvar condylomata</json:string><json:string>genital warts</json:string><json:string>penis</json:string><json:string>sexual abuse</json:string><json:string>cutaneous warts</json:string><json:string>anal condylomata</json:string><json:string>viral</json:string><json:string>virologic</json:string><json:string>common warts</json:string><json:string>perianal</json:string><json:string>lesion</json:string><json:string>cervical condylomata</json:string><json:string>anogenital warts</json:string><json:string>skin warts</json:string><json:string>human papillomavirus</json:string><json:string>anogenital condylomata</json:string><json:string>virologic studies</json:string><json:string>american academy</json:string><json:string>common hand warts</json:string><json:string>anal wart</json:string><json:string>wart</json:string><json:string>anogenital area</json:string><json:string>obstet gynecol</json:string><json:string>vulvar anal</json:string><json:string>genital papillomaviruses</json:string><json:string>blot hybridization</json:string><json:string>first week</json:string><json:string>histologic features</json:string><json:string>external condylomata</json:string></teeft></keywords><author><json:item><name>Slavomir Obalek MD</name><affiliations><json:string>From the Department of Dermatology, Warsaw School of Medicine, Warsaw, Poland</json:string><json:string>From the Unité des Papillomavirus, Unité INSERM 190, Institut Pasteur, Paris, France</json:string><json:string>*Recipient of a fellowship from the Fondation pour la Recherche Médicale.</json:string></affiliations></json:item><json:item><name>Stéfania Jablonska MD</name><affiliations><json:string>From the Department of Dermatology, Warsaw School of Medicine, Warsaw, Poland</json:string></affiliations></json:item><json:item><name>Michel Favre PhD</name><affiliations><json:string>From the Unité des Papillomavirus, Unité INSERM 190, Institut Pasteur, Paris, France</json:string></affiliations></json:item><json:item><name>Leszek Walczak MD</name><affiliations><json:string>From the Department of Dermatology, Warsaw School of Medicine, Warsaw, Poland</json:string></affiliations></json:item><json:item><name>Gérard Orth DVM</name><affiliations><json:string>From the Unité des Papillomavirus, Unité INSERM 190, Institut Pasteur, Paris, France</json:string><json:string>Reprint requests: Gérard Orth, DVM, Unité des Papillomavirus, Institut Pasteur, 25, rue du Docteur Roux, 75724 Paris Cedex 15, France.</json:string></affiliations></json:item></author><articleId><json:string>70200</json:string></articleId><arkIstex>ark:/67375/6H6-0WPZMNCK-G</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>Full-length article</json:string></originalGenre><abstract>To identify the papillomavirus types associated with condylomata acuminata in children and to evaluate their mode of transmission, we studied 32 children with anogenital warts. External condylomata were found in 12 of their mothers and in 10 of their fathers. Ten mothers, including two without external lesions, had cervical condylomata. Blot hybridization studies disclosed a genital human papillomavirus (HPV) in 14 of 27 children (HPV-6 in 12 and HPV-11 in two) and in 8 of 14 patients (HPV-6 in all). HPV-6 was found in another child by the polymerase chain reaction technique. Infection occurred most likely at birth or from nonsexual contact, but sexual abuse could not be excluded in one 11 -year-old girl. Cutaneous HPV-2 was found in seven children and as yet uncharacterized papillomaviruses were found in two children. Three mothers of HPV-2-infected children had common hand warts, and two children had subungual warts. This study shows the frequent nonsexual transmission of genital papillomaviruses in children and the unexpectedly high association of children's condylomata with papillomaviruses responsible for skin warts, possibly transmitted by heteroinoculation or autoinoculation.</abstract><qualityIndicators><score>8.555</score><pdfWordCount>4419</pdfWordCount><pdfCharCount>26560</pdfCharCount><pdfVersion>1.4</pdfVersion><pdfPageCount>9</pdfPageCount><pdfPageSize>597.6 x 842.4 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractWordCount>178</abstractWordCount><abstractCharCount>1201</abstractCharCount><keywordCount>0</keywordCount></qualityIndicators><title>Condylomata acuminata in children: Frequent association with human papillomaviruses responsible for cutaneous warts</title><pii><json:string>0190-9622(90)70200-2</json:string></pii><genre><json:string>research-article</json:string></genre><host><title>Journal of the American Academy of Dermatology</title><language><json:string>unknown</json:string></language><publicationDate>1990</publicationDate><issn><json:string>0190-9622</json:string></issn><pii><json:string>S0190-9622(05)X7134-1</json:string></pii><volume>23</volume><issue>2</issue><pages><first>205</first><last>213</last></pages><genre><json:string>journal</json:string></genre></host><namedEntities><unitex><date><json:string>16/1/17818</json:string><json:string>1990</json:string></date><geogName></geogName><orgName><json:string>Polish National Cancer Program</json:string><json:string>Collaborative Joint Program of the Institut National</json:string></orgName><orgName_funder><json:string>Collaborative Joint Program of the Institut National</json:string></orgName_funder><orgName_provider></orgName_provider><persName><json:string>Hung Bui</json:string><json:string>Leszek Walczak</json:string><json:string>Brigitte Rubat</json:string><json:string>Stefania Jablonska</json:string><json:string>Patricia Cassonnet</json:string><json:string>Patterns</json:string><json:string>L. Gissman</json:string><json:string>Roux</json:string><json:string>To</json:string><json:string>Michel Favre</json:string></persName><placeName><json:string>PY</json:string><json:string>Warsaw</json:string><json:string>France</json:string></placeName><ref_url></ref_url><ref_bibl><json:string>Obalek et al.</json:string><json:string>Saiki et al.</json:string></ref_bibl><bibl></bibl></unitex></namedEntities><ark><json:string>ark:/67375/6H6-0WPZMNCK-G</json:string></ark><categories><wos><json:string>1 - science</json:string><json:string>2 - dermatology</json:string></wos><scienceMetrix><json:string>1 - health sciences</json:string><json:string>2 - clinical medicine</json:string><json:string>3 - dermatology & venereal diseases</json:string></scienceMetrix><scopus><json:string>1 - Health Sciences</json:string><json:string>2 - Medicine</json:string><json:string>3 - Dermatology</json:string></scopus><inist><json:string>1 - sciences appliquees, technologies et medecines</json:string><json:string>2 - sciences biologiques et medicales</json:string><json:string>3 - sciences medicales</json:string><json:string>4 - pathologie infectieuse</json:string></inist></categories><publicationDate>1990</publicationDate><copyrightDate>1990</copyrightDate><doi><json:string>10.1016/0190-9622(90)70200-2</json:string></doi><id>A151382182153FE88A682DAAECB76D4645617F67</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/ark:/67375/6H6-0WPZMNCK-G/fulltext.pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/ark:/67375/6H6-0WPZMNCK-G/bundle.zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/ark:/67375/6H6-0WPZMNCK-G/fulltext.tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Condylomata acuminata in children: Frequent association with human papillomaviruses responsible for cutaneous warts</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher scheme="https://scientific-publisher.data.istex.fr">ELSEVIER</publisher><availability><licence><p>©1990 American Academy of Dermatology, Inc.</p></licence><p scheme="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-HKKZVM7B-M">elsevier</p></availability><date>1990</date></publicationStmt><notesStmt><note type="research-article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</note><note type="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note><note>Supported in part by a grant from the Collaborative Joint Program of the Institut National de la Santé et de la Recherche Médicale and from the Caisse Nationale d’Assurance Maladie des Travailleurs Salariés, and by the Polish National Cancer Program.</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Condylomata acuminata in children: Frequent association with human papillomaviruses responsible for cutaneous warts</title><author xml:id="author-0000"><persName><forename type="first">Slavomir</forename><surname>Obalek</surname></persName><roleName type="degree">MD</roleName><affiliation>From the Department of Dermatology, Warsaw School of Medicine, Warsaw, Poland</affiliation><affiliation>From the Unité des Papillomavirus, Unité INSERM 190, Institut Pasteur, Paris, France</affiliation><affiliation>*Recipient of a fellowship from the Fondation pour la Recherche Médicale.</affiliation></author><author xml:id="author-0001"><persName><forename type="first">Stéfania</forename><surname>Jablonska</surname></persName><roleName type="degree">MD</roleName><affiliation>From the Department of Dermatology, Warsaw School of Medicine, Warsaw, Poland</affiliation></author><author xml:id="author-0002"><persName><forename type="first">Michel</forename><surname>Favre</surname></persName><roleName type="degree">PhD</roleName><affiliation>From the Unité des Papillomavirus, Unité INSERM 190, Institut Pasteur, Paris, France</affiliation></author><author xml:id="author-0003"><persName><forename type="first">Leszek</forename><surname>Walczak</surname></persName><roleName type="degree">MD</roleName><affiliation>From the Department of Dermatology, Warsaw School of Medicine, Warsaw, Poland</affiliation></author><author xml:id="author-0004"><persName><forename type="first">Gérard</forename><surname>Orth</surname></persName><roleName type="degree">DVM</roleName><affiliation>From the Unité des Papillomavirus, Unité INSERM 190, Institut Pasteur, Paris, France</affiliation><affiliation>Reprint requests: Gérard Orth, DVM, Unité des Papillomavirus, Institut Pasteur, 25, rue du Docteur Roux, 75724 Paris Cedex 15, France.</affiliation></author><idno type="istex">A151382182153FE88A682DAAECB76D4645617F67</idno><idno type="ark">ark:/67375/6H6-0WPZMNCK-G</idno><idno type="DOI">10.1016/0190-9622(90)70200-2</idno><idno type="PII">0190-9622(90)70200-2</idno><idno type="article-id">70200</idno></analytic><monogr><title level="j">Journal of the American Academy of Dermatology</title><title level="j" type="abbrev">YMJD</title><idno type="pISSN">0190-9622</idno><idno type="PII">S0190-9622(05)X7134-1</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1990"></date><biblScope unit="volume">23</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="supplement">P1</biblScope><biblScope unit="page" from="205">205</biblScope><biblScope unit="page" to="213">213</biblScope></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>1990</date></creation><langUsage><language ident="en">en</language></langUsage><abstract><p>To identify the papillomavirus types associated with condylomata acuminata in children and to evaluate their mode of transmission, we studied 32 children with anogenital warts. External condylomata were found in 12 of their mothers and in 10 of their fathers. Ten mothers, including two without external lesions, had cervical condylomata. Blot hybridization studies disclosed a genital human papillomavirus (HPV) in 14 of 27 children (HPV-6 in 12 and HPV-11 in two) and in 8 of 14 patients (HPV-6 in all). HPV-6 was found in another child by the polymerase chain reaction technique. Infection occurred most likely at birth or from nonsexual contact, but sexual abuse could not be excluded in one 11 -year-old girl. Cutaneous HPV-2 was found in seven children and as yet uncharacterized papillomaviruses were found in two children. Three mothers of HPV-2-infected children had common hand warts, and two children had subungual warts. This study shows the frequent nonsexual transmission of genital papillomaviruses in children and the unexpectedly high association of children's condylomata with papillomaviruses responsible for skin warts, possibly transmitted by heteroinoculation or autoinoculation.</p></abstract></profileDesc><revisionDesc><change when="1990">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/6H6-0WPZMNCK-G/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Elsevier doc found" wicri:toSee="Elsevier, no converted or simple article"><istex:xmlDeclaration>version="1.0" encoding="utf-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//ES//DTD journal article DTD version 5.0.1//EN//XML" URI="art501.dtd" name="istex:docType"></istex:docType><istex:document><article version="5.0" xml:lang="en" docsubtype="fla"><item-info><jid>YMJD</jid><aid>70200</aid><ce:pii>0190-9622(90)70200-2</ce:pii><ce:doi>10.1016/0190-9622(90)70200-2</ce:doi><ce:copyright type="unknown" year="1990">American Academy of Dermatology, Inc.</ce:copyright></item-info><head><ce:article-footnote><ce:label>‡</ce:label><ce:note-para>Supported in part by a grant from the Collaborative Joint Program of the Institut National de la Santé et de la Recherche Médicale and from the Caisse Nationale d’Assurance Maladie des Travailleurs Salariés, and by the Polish National Cancer Program.</ce:note-para></ce:article-footnote><ce:title>Condylomata acuminata in children: Frequent association with human papillomaviruses responsible for cutaneous warts</ce:title><ce:author-group><ce:author><ce:given-name>Slavomir</ce:given-name><ce:surname>Obalek</ce:surname><ce:degrees>MD</ce:degrees><ce:cross-ref refid="aff1"><ce:sup>a</ce:sup></ce:cross-ref><ce:cross-ref refid="aff2"><ce:sup>b</ce:sup></ce:cross-ref><ce:cross-ref refid="fn1"><ce:sup>*</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Stéfania</ce:given-name><ce:surname>Jablonska</ce:surname><ce:degrees>MD</ce:degrees><ce:cross-ref refid="aff1"><ce:sup>a</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Michel</ce:given-name><ce:surname>Favre</ce:surname><ce:degrees>PhD</ce:degrees><ce:cross-ref refid="aff2"><ce:sup>b</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Leszek</ce:given-name><ce:surname>Walczak</ce:surname><ce:degrees>MD</ce:degrees><ce:cross-ref refid="aff1"><ce:sup>a</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Gérard</ce:given-name><ce:surname>Orth</ce:surname><ce:degrees>DVM</ce:degrees><ce:cross-ref refid="aff2"><ce:sup>b</ce:sup></ce:cross-ref><ce:cross-ref refid="cor1"><ce:sup>†</ce:sup></ce:cross-ref></ce:author><ce:affiliation id="aff1"><ce:label>a</ce:label><ce:textfn>From the Department of Dermatology, Warsaw School of Medicine, Warsaw, Poland</ce:textfn></ce:affiliation><ce:affiliation id="aff2"><ce:label>b</ce:label><ce:textfn>From the Unité des Papillomavirus, Unité INSERM 190, Institut Pasteur, Paris, France</ce:textfn></ce:affiliation><ce:correspondence id="cor1"><ce:label>†</ce:label><ce:text>Reprint requests: Gérard Orth, DVM, Unité des Papillomavirus, Institut Pasteur, 25, rue du Docteur Roux, 75724 Paris Cedex 15, France.</ce:text></ce:correspondence><ce:footnote id="fn1"><ce:label>*</ce:label><ce:note-para>Recipient of a fellowship from the Fondation pour la Recherche Médicale.</ce:note-para></ce:footnote></ce:author-group><ce:date-accepted day="29" month="10" year="1989"></ce:date-accepted><ce:abstract id="ab1"><ce:abstract-sec><ce:simple-para>To identify the papillomavirus types associated with condylomata acuminata in children and to evaluate their mode of transmission, we studied 32 children with anogenital warts. External condylomata were found in 12 of their mothers and in 10 of their fathers. Ten mothers, including two without external lesions, had cervical condylomata. Blot hybridization studies disclosed a genital human papillomavirus (HPV) in 14 of 27 children (HPV-6 in 12 and HPV-11 in two) and in 8 of 14 patients (HPV-6 in all). HPV-6 was found in another child by the polymerase chain reaction technique. Infection occurred most likely at birth or from nonsexual contact, but sexual abuse could not be excluded in one 11 -year-old girl. Cutaneous HPV-2 was found in seven children and as yet uncharacterized papillomaviruses were found in two children. Three mothers of HPV-2-infected children had common hand warts, and two children had subungual warts. This study shows the frequent nonsexual transmission of genital papillomaviruses in children and the unexpectedly high association of children's condylomata with papillomaviruses responsible for skin warts, possibly transmitted by heteroinoculation or autoinoculation.</ce:simple-para></ce:abstract-sec></ce:abstract></head><tail><ce:bibliography><ce:section-title>References</ce:section-title><ce:bibliography-sec><ce:bib-reference id="bib1"><ce:label>1.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>JD</ce:given-name><ce:surname>Oriel</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Natural history of genital warts</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Br J Verier Dis</sb:maintitle></sb:title><sb:volume-nr>47</sb:volume-nr></sb:series><sb:date>1971</sb:date></sb:issue><sb:pages><sb:first-page>1</sb:first-page><sb:last-page>13</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib2"><ce:label>2.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>L</ce:given-name><ce:surname>Gissmann</ce:surname></sb:author><sb:author><ce:given-name>H</ce:given-name><ce:surname>zur Hausen</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Partial characterization of viral DNA from human genital warts (condylomata acuminata)</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Int J Cancer</sb:maintitle></sb:title><sb:volume-nr>25</sb:volume-nr></sb:series><sb:date>1980</sb:date></sb:issue><sb:pages><sb:first-page>605</sb:first-page><sb:last-page>609</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib3"><ce:label>3.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>EM</ce:given-name><ce:surname>de Villiers</ce:surname></sb:author><sb:author><ce:given-name>L</ce:given-name><ce:surname>Gissmann</ce:surname></sb:author><sb:author><ce:given-name>H</ce:given-name><ce:surname>zur Hausen</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Molecular cloning of viral DNA from human genital warts</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>J Virol</sb:maintitle></sb:title><sb:volume-nr>40</sb:volume-nr></sb:series><sb:date>1981</sb:date></sb:issue><sb:pages><sb:first-page>932</sb:first-page><sb:last-page>935</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib4"><ce:label>4.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>L</ce:given-name><ce:surname>Gissmann</ce:surname></sb:author><sb:author><ce:given-name>EM</ce:given-name><ce:surname>de Villiers</ce:surname></sb:author><sb:author><ce:given-name>H</ce:given-name><ce:surname>zur Hausen</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Analysis of human genital warts (condylomata acuminata) and other genital tumors for human papillomavirus type 6 DNA</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Int J Cancer</sb:maintitle></sb:title><sb:volume-nr>29</sb:volume-nr></sb:series><sb:date>1982</sb:date></sb:issue><sb:pages><sb:first-page>143</sb:first-page><sb:last-page>146</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib5"><ce:label>5.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>L</ce:given-name><ce:surname>Gissmann</ce:surname></sb:author><sb:author><ce:given-name>L</ce:given-name><ce:surname>Wolnik</ce:surname></sb:author><sb:author><ce:given-name>H</ce:given-name><ce:surname>Ikenberg</ce:surname></sb:author><sb:et-al></sb:et-al></sb:authors><sb:title><sb:maintitle>Human papillomavirus type 6 and 11 DNA sequences in genital and laryngeal papillomas and in some cervical cancers</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Proc Natl Acad Sci USA</sb:maintitle></sb:title><sb:volume-nr>80</sb:volume-nr></sb:series><sb:date>1983</sb:date></sb:issue><sb:pages><sb:first-page>560</sb:first-page><sb:last-page>563</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib6"><ce:label>6.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>RA</ce:given-name><ce:surname>Krzyzek</ce:surname></sb:author><sb:author><ce:given-name>SL</ce:given-name><ce:surname>Watts</ce:surname></sb:author><sb:author><ce:given-name>DL</ce:given-name><ce:surname>Anderson</ce:surname></sb:author><sb:et-al></sb:et-al></sb:authors><sb:title><sb:maintitle>Anogenital warts contain several distinct species of human papillomavirus</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>J Virol</sb:maintitle></sb:title><sb:volume-nr>36</sb:volume-nr></sb:series><sb:date>1980</sb:date></sb:issue><sb:pages><sb:first-page>236</sb:first-page><sb:last-page>244</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib7"><ce:label>7.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>M</ce:given-name><ce:surname>Green</ce:surname></sb:author><sb:author><ce:given-name>KH</ce:given-name><ce:surname>Brackmann</ce:surname></sb:author><sb:author><ce:given-name>PR</ce:given-name><ce:surname>Sanders</ce:surname></sb:author><sb:et-al></sb:et-al></sb:authors><sb:title><sb:maintitle>Isolation of a human papillomavirus from a patient with epidermodysplasia verruciformis: presence of related viral DNA genomes in human urogenital tumors</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Proc Natl Acad Sci USA</sb:maintitle></sb:title><sb:volume-nr>79</sb:volume-nr></sb:series><sb:date>1982</sb:date></sb:issue><sb:pages><sb:first-page>4437</sb:first-page><sb:last-page>4441</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib8"><ce:label>8.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>S</ce:given-name><ce:surname>Beaudenon</ce:surname></sb:author><sb:author><ce:given-name>D</ce:given-name><ce:surname>Kremsdorf</ce:surname></sb:author><sb:author><ce:given-name>S</ce:given-name><ce:surname>Obalek</ce:surname></sb:author><sb:et-al></sb:et-al></sb:authors><sb:title><sb:maintitle>Plurality of genital papillomaviruses: characterization of two new types with distinct biological properties</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Virology</sb:maintitle></sb:title><sb:volume-nr>161</sb:volume-nr></sb:series><sb:date>1987</sb:date></sb:issue><sb:pages><sb:first-page>374</sb:first-page><sb:last-page>384</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib9"><ce:label>9.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>R</ce:given-name><ce:surname>Reid</ce:surname></sb:author><sb:author><ce:given-name>M</ce:given-name><ce:surname>Greenberg</ce:surname></sb:author><sb:author><ce:given-name>BA</ce:given-name><ce:surname>Jenson</ce:surname></sb:author><sb:et-al></sb:et-al></sb:authors><sb:title><sb:maintitle>Sexually transmitted papilloma-viral infection. I. The anatomic distribution and pathologic grade of neoplastic lesions associated with different viral types</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Am J Obstet Gynecol</sb:maintitle></sb:title><sb:volume-nr>156</sb:volume-nr></sb:series><sb:date>1987</sb:date></sb:issue><sb:pages><sb:first-page>212</sb:first-page><sb:last-page>222</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib10"><ce:label>10.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>LA</ce:given-name><ce:surname>Koutsky</ce:surname></sb:author><sb:author><ce:given-name>DA</ce:given-name><ce:surname>Galloway</ce:surname></sb:author><sb:author><ce:given-name>KK</ce:given-name><ce:surname>Holmes</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Epidemiology of genital human papillomavirus infection</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Epidemiol Rev</sb:maintitle></sb:title><sb:volume-nr>10</sb:volume-nr></sb:series><sb:date>1988</sb:date></sb:issue><sb:pages><sb:first-page>122</sb:first-page><sb:last-page>163</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib11"><ce:label>11.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>MS</ce:given-name><ce:surname>Eftaiha</ce:surname></sb:author><sb:author><ce:given-name>AL</ce:given-name><ce:surname>Amshel</ce:surname></sb:author><sb:author><ce:given-name>IL</ce:given-name><ce:surname>Shonberg</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Condylomata acuminata in an infant and mother: report of a case</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Dis Colon Rectum</sb:maintitle></sb:title><sb:volume-nr>21</sb:volume-nr></sb:series><sb:date>1978</sb:date></sb:issue><sb:pages><sb:first-page>369</sb:first-page><sb:last-page>371</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib12"><ce:label>12.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>J</ce:given-name><ce:surname>Seidel</ce:surname></sb:author><sb:author><ce:given-name>J</ce:given-name><ce:surname>Zonana</ce:surname></sb:author><sb:author><ce:given-name>E</ce:given-name><ce:surname>Totten</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Condylomata acuminata as a sign of sexual abuse in children</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>J Pediatr</sb:maintitle></sb:title><sb:volume-nr>95</sb:volume-nr></sb:series><sb:date>1979</sb:date></sb:issue><sb:pages><sb:first-page>553</sb:first-page><sb:last-page>554</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib13"><ce:label>13.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>PG</ce:given-name><ce:surname>Stumpf</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Increasing occurrence of condylomata acuminata in premenarchal children</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Obstet Gynecol</sb:maintitle></sb:title><sb:volume-nr>56</sb:volume-nr></sb:series><sb:date>1980</sb:date></sb:issue><sb:pages><sb:first-page>262</sb:first-page><sb:last-page>264</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib14"><ce:label>14.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>A</ce:given-name><ce:surname>Ingber</ce:surname></sb:author><sb:author><ce:given-name>MH</ce:given-name><ce:surname>Grunwald</ce:surname></sb:author><sb:author><ce:given-name>EJ</ce:given-name><ce:surname>Feuerman</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Perianale condylomata acuminata bei einem 13-Monate alten Mädchen</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Z Hautkr</sb:maintitle></sb:title><sb:volume-nr>58</sb:volume-nr></sb:series><sb:date>1982</sb:date></sb:issue><sb:pages><sb:first-page>1200</sb:first-page><sb:last-page>1202</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib15"><ce:label>15.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>AR</ce:given-name><ce:surname>De Jong</ce:surname></sb:author><sb:author><ce:given-name>JC</ce:given-name><ce:surname>Weiss</ce:surname></sb:author><sb:author><ce:given-name>RL</ce:given-name><ce:surname>Brent</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Condylomata acuminata in children</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Am J Dis Child</sb:maintitle></sb:title><sb:volume-nr>136</sb:volume-nr></sb:series><sb:date>1982</sb:date></sb:issue><sb:pages><sb:first-page>704</sb:first-page><sb:last-page>706</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib16"><ce:label>16.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>KG</ce:given-name><ce:surname>Singh</ce:surname></sb:author><sb:author><ce:given-name>AK</ce:given-name><ce:surname>Bajaj</ce:surname></sb:author><sb:author><ce:given-name>R</ce:given-name><ce:surname>Sharma</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Perianal condylomata acuminata in an infant</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Int J Dermatol</sb:maintitle></sb:title><sb:volume-nr>27</sb:volume-nr></sb:series><sb:date>1988</sb:date></sb:issue><sb:pages><sb:first-page>181</sb:first-page><sb:last-page>182</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib17"><ce:label>17.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>B</ce:given-name><ce:surname>Rock</ce:surname></sb:author><sb:author><ce:given-name>Z</ce:given-name><ce:surname>Naghashfar</ce:surname></sb:author><sb:author><ce:given-name>N</ce:given-name><ce:surname>Barnett</ce:surname></sb:author><sb:et-al></sb:et-al></sb:authors><sb:title><sb:maintitle>Genital tract papillomavirus infection in children</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Arch Dermatol</sb:maintitle></sb:title><sb:volume-nr>122</sb:volume-nr></sb:series><sb:date>1986</sb:date></sb:issue><sb:pages><sb:first-page>1129</sb:first-page><sb:last-page>1132</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib18"><ce:label>18.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>H</ce:given-name><ce:surname>Vallejos</ce:surname></sb:author><sb:author><ce:given-name>A</ce:given-name><ce:surname>Del Mistro</ce:surname></sb:author><sb:author><ce:given-name>S</ce:given-name><ce:surname>Kleinhaus</ce:surname></sb:author><sb:et-al></sb:et-al></sb:authors><sb:title><sb:maintitle>Characterization of human papilloma virus types in condylomata acuminata in children by in situ hybridization</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Lab Invest</sb:maintitle></sb:title><sb:volume-nr>56</sb:volume-nr></sb:series><sb:date>1987</sb:date></sb:issue><sb:pages><sb:first-page>611</sb:first-page><sb:last-page>615</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib19"><ce:label>19.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>KA</ce:given-name><ce:surname>Fleming</ce:surname></sb:author><sb:author><ce:given-name>V</ce:given-name><ce:surname>Venning</ce:surname></sb:author><sb:author><ce:given-name>M</ce:given-name><ce:surname>Evans</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>DNA typing of genital warts and diagnosis of sexual abuse of children [Letter]</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Lancet</sb:maintitle></sb:title><sb:volume-nr>2</sb:volume-nr></sb:series><sb:date>1987</sb:date></sb:issue><sb:pages><sb:first-page>454</sb:first-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib20"><ce:label>20.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>JD</ce:given-name><ce:surname>Oriel</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Anogenital papillomavirus infection in children</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Br Med J</sb:maintitle></sb:title><sb:volume-nr>296</sb:volume-nr></sb:series><sb:date>1988</sb:date></sb:issue><sb:pages><sb:first-page>1484</sb:first-page><sb:last-page>1485</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib21"><ce:label>21.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>L</ce:given-name><ce:surname>Schachner</ce:surname></sb:author><sb:author><ce:given-name>DE</ce:given-name><ce:surname>Hankin</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Assessing child abuse in childhood condyloma acuminatum</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>J Am Acad Dermatol</sb:maintitle></sb:title><sb:volume-nr>12</sb:volume-nr></sb:series><sb:date>1985</sb:date></sb:issue><sb:pages><sb:first-page>157</sb:first-page><sb:last-page>160</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib22"><ce:label>22.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>R</ce:given-name><ce:surname>Barrasse</ce:surname></sb:author><sb:author><ce:given-name>J</ce:given-name><ce:surname>de Brüx</ce:surname></sb:author><sb:author><ce:given-name>O</ce:given-name><ce:surname>Croissant</ce:surname></sb:author><sb:et-al></sb:et-al></sb:authors><sb:title><sb:maintitle>High prevalence of papillomavirus-associated penile intraepithelial neoplasia in sexual partners of women with cervical intraepithelial neoplasia</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>N Engl J Med</sb:maintitle></sb:title><sb:volume-nr>317</sb:volume-nr></sb:series><sb:date>1987</sb:date></sb:issue><sb:pages><sb:first-page>916</sb:first-page><sb:last-page>923</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib23"><ce:label>23.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>RK</ce:given-name><ce:surname>Saiki</ce:surname></sb:author><sb:author><ce:given-name>S</ce:given-name><ce:surname>Scharf</ce:surname></sb:author><sb:author><ce:given-name>F</ce:given-name><ce:surname>Faloona</ce:surname></sb:author><sb:et-al></sb:et-al></sb:authors><sb:title><sb:maintitle>Enzymatic amplification of <ce:italic>β</ce:italic>-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Science</sb:maintitle></sb:title><sb:volume-nr>230</sb:volume-nr></sb:series><sb:date>1985</sb:date></sb:issue><sb:pages><sb:first-page>1350</sb:first-page><sb:last-page>1354</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib24"><ce:label>24.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>G</ce:given-name><ce:surname>Orth</ce:surname></sb:author><sb:author><ce:given-name>M</ce:given-name><ce:surname>Favre</ce:surname></sb:author><sb:author><ce:given-name>O</ce:given-name><ce:surname>Croissant</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Characterization of a new type of human papillomavirus that causes skin warts</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>J Virol</sb:maintitle></sb:title><sb:volume-nr>24</sb:volume-nr></sb:series><sb:date>1977</sb:date></sb:issue><sb:pages><sb:first-page>108</sb:first-page><sb:last-page>120</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib25"><ce:label>25.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>PG</ce:given-name><ce:surname>Fuchs</ce:surname></sb:author><sb:author><ce:given-name>H</ce:given-name><ce:surname>Pfister</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Cloning and characterization of papillomavirus type 2c DNA</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Intervirology</sb:maintitle></sb:title><sb:volume-nr>22</sb:volume-nr></sb:series><sb:date>1984</sb:date></sb:issue><sb:pages><sb:first-page>177</sb:first-page><sb:last-page>180</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib26"><ce:label>26.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>G</ce:given-name><ce:surname>Orth</ce:surname></sb:author><sb:author><ce:given-name>S</ce:given-name><ce:surname>Jablonska</ce:surname></sb:author><sb:author><ce:given-name>M</ce:given-name><ce:surname>Favre</ce:surname></sb:author><sb:et-al></sb:et-al></sb:authors><sb:title><sb:maintitle>Identification of papillomaviruses in butchers' warts</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>J Invest Dermatol</sb:maintitle></sb:title><sb:volume-nr>26</sb:volume-nr></sb:series><sb:date>1981</sb:date></sb:issue><sb:pages><sb:first-page>97</sb:first-page><sb:last-page>102</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib27"><ce:label>27.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>S</ce:given-name><ce:surname>Jablonska</ce:surname></sb:author><sb:author><ce:given-name>G</ce:given-name><ce:surname>Orth</ce:surname></sb:author><sb:author><ce:given-name>S</ce:given-name><ce:surname>Obalek</ce:surname></sb:author><sb:et-al></sb:et-al></sb:authors><sb:title><sb:maintitle>Cutaneous warts: clinical, histologie and virologie correlations</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Clin Dermatol</sb:maintitle></sb:title><sb:volume-nr>3</sb:volume-nr></sb:series><sb:issue-nr>4</sb:issue-nr><sb:date>1985</sb:date></sb:issue><sb:pages><sb:first-page>71</sb:first-page><sb:last-page>82</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib28"><ce:label>28.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>H</ce:given-name><ce:surname>zur Hausen</ce:surname></sb:author><sb:author><ce:given-name>A</ce:given-name><ce:surname>Schneider</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>The role of papillomaviruses in human anogenital cancer</sb:maintitle></sb:title></sb:contribution><sb:host><sb:edited-book><sb:editors><sb:editor><ce:given-name>NP</ce:given-name><ce:surname>Salzman</ce:surname></sb:editor><sb:editor><ce:given-name>PM</ce:given-name><ce:surname>Howley</ce:surname></sb:editor></sb:editors><sb:title><sb:maintitle>The papovaviridae; vol 2. The papillomaviruses</sb:maintitle></sb:title><sb:date>1987</sb:date><sb:publisher><sb:name>Plenum Press</sb:name><sb:location>New York</sb:location></sb:publisher></sb:edited-book><sb:pages><sb:first-page>245</sb:first-page><sb:last-page>263</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib29"><ce:label>29.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>M</ce:given-name><ce:surname>Grimmel</ce:surname></sb:author><sb:author><ce:given-name>E-M</ce:given-name><ce:surname>de Villiers</ce:surname></sb:author><sb:author><ce:given-name>C</ce:given-name><ce:surname>Neumann</ce:surname></sb:author><sb:et-al></sb:et-al></sb:authors><sb:title><sb:maintitle>Characterization of a new human papillomavirus (HPV41) from disseminated warts and detection of its DNA in some skin carcinomas</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Int J Cancer</sb:maintitle></sb:title><sb:volume-nr>41</sb:volume-nr></sb:series><sb:date>1988</sb:date></sb:issue><sb:pages><sb:first-page>5</sb:first-page><sb:last-page>9</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib30"><ce:label>30.</ce:label><ce:other-ref><ce:textref>Favre M, Kremsdorf D, Jablonska S, et al. Two new human papillomavirus types (HPV-54and-55) characterized from genital tumours illustrate the plurality of genital HPVs. Int J Cancer (in press).</ce:textref></ce:other-ref></ce:bib-reference><ce:bib-reference id="bib31"><ce:label>31.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>P</ce:given-name><ce:surname>Mounts</ce:surname></sb:author><sb:author><ce:given-name>KV</ce:given-name><ce:surname>Shah</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Respiratory papillomatosis; etiological relation to genital tract papillomaviruses</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Prog Med Virol</sb:maintitle></sb:title><sb:volume-nr>29</sb:volume-nr></sb:series><sb:date>1984</sb:date></sb:issue><sb:pages><sb:first-page>90</sb:first-page><sb:last-page>114</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib32"><ce:label>32.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>E</ce:given-name><ce:surname>Hajek</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Contribution to the etiology of laryngeal papilloma in children</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>J Laryngol Otol</sb:maintitle></sb:title><sb:volume-nr>70</sb:volume-nr></sb:series><sb:date>1956</sb:date></sb:issue><sb:pages><sb:first-page>166</sb:first-page><sb:last-page>168</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib33"><ce:label>33.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>C-K</ce:given-name><ce:surname>Tang</ce:surname></sb:author><sb:author><ce:given-name>DW</ce:given-name><ce:surname>Shermeta</ce:surname></sb:author><sb:author><ce:given-name>C</ce:given-name><ce:surname>Wood</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>Congenital condylomata acuminata</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Am J Obstet Gynecol</sb:maintitle></sb:title><sb:volume-nr>131</sb:volume-nr></sb:series><sb:date>1978</sb:date></sb:issue><sb:pages><sb:first-page>912</sb:first-page><sb:last-page>913</sb:last-page></sb:pages></sb:host></sb:reference></ce:bib-reference><ce:bib-reference id="bib34"><ce:label>34.</ce:label><sb:reference><sb:contribution><sb:authors><sb:author><ce:given-name>A</ce:given-name><ce:surname>Ferenczy</ce:surname></sb:author><sb:author><ce:given-name>C</ce:given-name><ce:surname>Bergeron</ce:surname></sb:author><sb:author><ce:given-name>R</ce:given-name><ce:surname>Richart</ce:surname></sb:author></sb:authors><sb:title><sb:maintitle>HPV DNA in fomites used for the management of patients with genital HPV infections</sb:maintitle></sb:title></sb:contribution><sb:host><sb:issue><sb:series><sb:title><sb:maintitle>Obstet Gynecol</sb:maintitle></sb:title></sb:series><sb:date>1989</sb:date></sb:issue></sb:host><sb:comment>(In press.)</sb:comment></sb:reference></ce:bib-reference></ce:bibliography-sec></ce:bibliography></tail></article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Condylomata acuminata in children: Frequent association with human papillomaviruses responsible for cutaneous warts</title></titleInfo><titleInfo type="alternative" lang="en" contentType="CDATA"><title>Condylomata acuminata in children: Frequent association with human papillomaviruses responsible for cutaneous warts</title></titleInfo><name type="personal"><namePart type="given">Slavomir</namePart><namePart type="family">Obalek</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>From the Department of Dermatology, Warsaw School of Medicine, Warsaw, Poland</affiliation><affiliation>From the Unité des Papillomavirus, Unité INSERM 190, Institut Pasteur, Paris, France</affiliation><affiliation>*Recipient of a fellowship from the Fondation pour la Recherche Médicale.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Stéfania</namePart><namePart type="family">Jablonska</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>From the Department of Dermatology, Warsaw School of Medicine, Warsaw, Poland</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Michel</namePart><namePart type="family">Favre</namePart><namePart type="termsOfAddress">PhD</namePart><affiliation>From the Unité des Papillomavirus, Unité INSERM 190, Institut Pasteur, Paris, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Leszek</namePart><namePart type="family">Walczak</namePart><namePart type="termsOfAddress">MD</namePart><affiliation>From the Department of Dermatology, Warsaw School of Medicine, Warsaw, Poland</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Gérard</namePart><namePart type="family">Orth</namePart><namePart type="termsOfAddress">DVM</namePart><affiliation>From the Unité des Papillomavirus, Unité INSERM 190, Institut Pasteur, Paris, France</affiliation><affiliation>Reprint requests: Gérard Orth, DVM, Unité des Papillomavirus, Institut Pasteur, 25, rue du Docteur Roux, 75724 Paris Cedex 15, France.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="Full-length article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">1990</dateIssued><copyrightDate encoding="w3cdtf">1990</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><abstract>To identify the papillomavirus types associated with condylomata acuminata in children and to evaluate their mode of transmission, we studied 32 children with anogenital warts. External condylomata were found in 12 of their mothers and in 10 of their fathers. Ten mothers, including two without external lesions, had cervical condylomata. Blot hybridization studies disclosed a genital human papillomavirus (HPV) in 14 of 27 children (HPV-6 in 12 and HPV-11 in two) and in 8 of 14 patients (HPV-6 in all). HPV-6 was found in another child by the polymerase chain reaction technique. Infection occurred most likely at birth or from nonsexual contact, but sexual abuse could not be excluded in one 11 -year-old girl. Cutaneous HPV-2 was found in seven children and as yet uncharacterized papillomaviruses were found in two children. Three mothers of HPV-2-infected children had common hand warts, and two children had subungual warts. This study shows the frequent nonsexual transmission of genital papillomaviruses in children and the unexpectedly high association of children's condylomata with papillomaviruses responsible for skin warts, possibly transmitted by heteroinoculation or autoinoculation.</abstract><note>Supported in part by a grant from the Collaborative Joint Program of the Institut National de la Santé et de la Recherche Médicale and from the Caisse Nationale d’Assurance Maladie des Travailleurs Salariés, and by the Polish National Cancer Program.</note><relatedItem type="host"><titleInfo><title>Journal of the American Academy of Dermatology</title></titleInfo><titleInfo type="abbreviated"><title>YMJD</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">1990</dateIssued></originInfo><identifier type="ISSN">0190-9622</identifier><identifier type="PII">S0190-9622(05)X7134-1</identifier><part><date>1990</date><detail type="volume"><number>23</number><caption>vol.</caption></detail><detail type="issue"><number>2</number><caption>no.</caption></detail><detail type="supplement"><number>P1</number><caption>Suppl.</caption></detail><extent unit="issue-pages"><start>167</start><end>330</end></extent><extent unit="pages"><start>205</start><end>213</end></extent></part></relatedItem><identifier type="istex">A151382182153FE88A682DAAECB76D4645617F67</identifier><identifier type="ark">ark:/67375/6H6-0WPZMNCK-G</identifier><identifier type="DOI">10.1016/0190-9622(90)70200-2</identifier><identifier type="PII">0190-9622(90)70200-2</identifier><identifier type="ArticleID">70200</identifier><accessCondition type="use and reproduction" contentType="copyright">©1990 American Academy of Dermatology, Inc.</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-HKKZVM7B-M">elsevier</recordContentSource><recordOrigin>American Academy of Dermatology, Inc., ©1990</recordOrigin></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/ark:/67375/6H6-0WPZMNCK-G/record.json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001653 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 001653 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= MersV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:A151382182153FE88A682DAAECB76D4645617F67
|texte= Condylomata acuminata in children: Frequent association with human papillomaviruses responsible for cutaneous warts
}}
| This area was generated with Dilib version V0.6.33. |  |