Comparison of the effects of rabies virus infection and of combined interferon and poly(I) · poly(C) treatment on the levels of 2′,5′-adenyladenosine oligonucleotides in different organs of mice
Identifieur interne : 000927 ( Istex/Corpus ); précédent : 000926; suivant : 000928Comparison of the effects of rabies virus infection and of combined interferon and poly(I) · poly(C) treatment on the levels of 2′,5′-adenyladenosine oligonucleotides in different organs of mice
Auteurs : Liliane Laurence ; Danièle Roux ; Hélène Cailla ; Yves Riviere ; Rugimar Marcovistz ; Ara HovanessianSource :
- Virology [ 0042-6822 ] ; 1985.
English descriptors
- Teeft :
- Academic press, Baglioni, Control values, Cultured cells, Different organs, Dimer, Greater length, Hovanessian, Hplc, Hplc fractionation, Infection, Interferon, Interferon action, Interferon system, Mouse, Nilsen, Noninfected, Noninfected mice, Nonphosphorylated oligonucleotides, Oligomers, Oligonucleotides, Phosphorylated, Phosphorylated oligonucleotides, Proc nat1, Protein synthesis, Rabies, Rabies mice, Rabies virus, Rabies virus infection, Radioimmunoassay, Spleen, Synthetase, Viral, Virus infection.
Abstract
Abstract: Intracellular levels of 2′,5′-adenyladenosine oligonucleotides were analyzed in different organs of mice during the course of λ rabies virus infection. Phosphorylated and nonphosphorylated 2′,5′-adenyladenosine oligonucleotides were measured by radioimmunoassay and analyzed further by HPLC. As the infection progressed, concentrations of phosphorylated 2′,5′-adenyladenosine oligonucleotides increased strongly, reaching their maxima late in the infection. In contrast, concentrations of the nonphosphorylated 2′,5′-adenyladenosine oligonucleotides decreased. A similar phenomenon was observed in spleens analyzed at intervals after treatment of noninfected mice with interferon and poly(l) · poly(C) and to λ lesser extent after treatment with poly(I) · poly(C) alone, but not after treatment with interferon alone. The products which accumulated during virus infection were primarily phosphorylated dimers whereas during combined interferon and poly(I) · poly(C) treatment, the entire range of phosphorylated molecules from dimer to pentamer was present. These data show that infection of mice with rabies virus provokes both the induction and the activation of 2–5A synthetase, as does interferon and poly(I) · poly(C) treatment. However, our data indicate that the intracellular products are different in the two situations: the species active on the nuclease were only detected in interferon- and poly(I) · poly(C)-treated mice. The absence of molecules able to activate the 2–5A-dependent nuclease in virus-infected mice might well be one of the reasons why the interferon system is ineffective in rabies virus infection.
Url:
DOI: 10.1016/0042-6822(85)90116-3
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ISTEX:2DA08B6B0C4336D39B4DDE3BE46872EA36FEA904Le document en format XML
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synthesis</term><term>Rabies</term><term>Rabies mice</term><term>Rabies virus</term><term>Rabies virus infection</term><term>Radioimmunoassay</term><term>Spleen</term><term>Synthetase</term><term>Viral</term><term>Virus infection</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Intracellular levels of 2′,5′-adenyladenosine oligonucleotides were analyzed in different organs of mice during the course of λ rabies virus infection. Phosphorylated and nonphosphorylated 2′,5′-adenyladenosine oligonucleotides were measured by radioimmunoassay and analyzed further by HPLC. As the infection progressed, concentrations of phosphorylated 2′,5′-adenyladenosine oligonucleotides increased strongly, reaching their maxima late in the infection. In contrast, concentrations of the nonphosphorylated 2′,5′-adenyladenosine oligonucleotides decreased. A similar phenomenon was observed in spleens analyzed at intervals after treatment of noninfected mice with interferon and poly(l) · poly(C) and to λ lesser extent after treatment with poly(I) · poly(C) alone, but not after treatment with interferon alone. The products which accumulated during virus infection were primarily phosphorylated dimers whereas during combined interferon and poly(I) · poly(C) treatment, the entire range of phosphorylated molecules from dimer to pentamer was present. These data show that infection of mice with rabies virus provokes both the induction and the activation of 2–5A synthetase, as does interferon and poly(I) · poly(C) treatment. However, our data indicate that the intracellular products are different in the two situations: the species active on the nuclease were only detected in interferon- and poly(I) · poly(C)-treated mice. 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Phosphorylated and nonphosphorylated 2′,5′-adenyladenosine oligonucleotides were measured by radioimmunoassay and analyzed further by HPLC. As the infection progressed, concentrations of phosphorylated 2′,5′-adenyladenosine oligonucleotides increased strongly, reaching their maxima late in the infection. In contrast, concentrations of the nonphosphorylated 2′,5′-adenyladenosine oligonucleotides decreased. A similar phenomenon was observed in spleens analyzed at intervals after treatment of noninfected mice with interferon and poly(l) · poly(C) and to λ lesser extent after treatment with poly(I) · poly(C) alone, but not after treatment with interferon alone. The products which accumulated during virus infection were primarily phosphorylated dimers whereas during combined interferon and poly(I) · poly(C) treatment, the entire range of phosphorylated molecules from dimer to pentamer was present. These data show that infection of mice with rabies virus provokes both the induction and the activation of 2–5A synthetase, as does interferon and poly(I) · poly(C) treatment. However, our data indicate that the intracellular products are different in the two situations: the species active on the nuclease were only detected in interferon- and poly(I) · poly(C)-treated mice. The absence of molecules able to activate the 2–5A-dependent nuclease in virus-infected mice might well be one of the reasons why the interferon system is ineffective in rabies virus infection.</abstract><qualityIndicators><score>8.45</score><pdfWordCount>3786</pdfWordCount><pdfCharCount>28450</pdfCharCount><pdfVersion>1.3</pdfVersion><pdfPageCount>10</pdfPageCount><pdfPageSize>504 x 720 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractWordCount>222</abstractWordCount><abstractCharCount>1638</abstractCharCount><keywordCount>0</keywordCount></qualityIndicators><title>Comparison of the effects of rabies virus infection and of combined interferon and poly(I) · poly(C) treatment on the levels of 2′,5′-adenyladenosine oligonucleotides in different organs of mice</title><pmid><json:string>4060581</json:string></pmid><pii><json:string>0042-6822(85)90116-3</json:string></pii><genre><json:string>research-article</json:string></genre><serie><title>Proc. Natl. Acad. Sci. 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Rickenberg</json:string></persName><placeName><json:string>France</json:string></placeName><ref_url></ref_url><ref_bibl><json:string>Williams et ab, 1979</json:string><json:string>Nilsen et al, 1982b</json:string><json:string>[1251]</json:string><json:string>Johnson and Mercer, 1984</json:string><json:string>Marcovistz et al, 1984</json:string><json:string>Hovanessian et al, 1981</json:string><json:string>Hovanessian and Wood, 1980</json:string><json:string>Hovanessian et al</json:string><json:string>Kerr et d, 1983</json:string><json:string>Hovanessian and Riviere, 1980</json:string><json:string>Williams et al, 1979</json:string><json:string>Nilsen et aL, 1982a</json:string><json:string>Laurence et al, 1984</json:string><json:string>Nilsen et al, 1981</json:string><json:string>Kerr et ah, 1983</json:string><json:string>Williams and Kerr, 1978</json:string><json:string>Epstein et ah, 1983</json:string><json:string>Nilsen et al., 1982a</json:string><json:string>Cailla et al, 1982</json:string><json:string>Kerr and Brown, 1978</json:string><json:string>Etienne-Smekens et al, 1983</json:string><json:string>Hersh et al, 1984</json:string><json:string>Silverman et aL, 1982</json:string><json:string>Clemens and Williams, 1978</json:string><json:string>Krust et aL, 1982</json:string><json:string>Baglioni et al, 1978</json:string><json:string>LD& into the footpad (Marcovistz et cd, 1984</json:string><json:string>Krust et al, 1982</json:string></ref_bibl><bibl></bibl></unitex></namedEntities><ark><json:string>ark:/67375/6H6-KPXMKMM6-X</json:string></ark><categories><wos><json:string>1 - science</json:string><json:string>2 - virology</json:string></wos><scienceMetrix><json:string>1 - health sciences</json:string><json:string>2 - biomedical research</json:string><json:string>3 - virology</json:string></scienceMetrix><scopus><json:string>1 - Life Sciences</json:string><json:string>2 - Immunology and Microbiology</json:string><json:string>3 - Virology</json:string></scopus><inist><json:string>1 - sciences appliquees, technologies et medecines</json:string><json:string>2 - sciences biologiques et medicales</json:string><json:string>3 - sciences medicales</json:string></inist></categories><publicationDate>1985</publicationDate><copyrightDate>1985</copyrightDate><doi><json:string>10.1016/0042-6822(85)90116-3</json:string></doi><id>2DA08B6B0C4336D39B4DDE3BE46872EA36FEA904</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/ark:/67375/6H6-KPXMKMM6-X/fulltext.pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/ark:/67375/6H6-KPXMKMM6-X/bundle.zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/ark:/67375/6H6-KPXMKMM6-X/fulltext.tei"><teiHeader><fileDesc><titleStmt><title level="a">Comparison of the effects of rabies virus infection and of combined interferon and poly(I) · poly(C) treatment on the levels of 2′,5′-adenyladenosine oligonucleotides in different organs of mice</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher scheme="https://scientific-publisher.data.istex.fr">ELSEVIER</publisher><availability><licence><p>elsevier</p></licence></availability><p scheme="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-HKKZVM7B-M"></p><date>1985</date></publicationStmt><notesStmt><note type="research-article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</note><note type="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a">Comparison of the effects of rabies virus infection and of combined interferon and poly(I) · poly(C) treatment on the levels of 2′,5′-adenyladenosine oligonucleotides in different organs of mice</title><author xml:id="author-0000"><persName><forename type="first">Liliane</forename><surname>Laurence</surname></persName><note type="biography">To whom requests for reprints should be addressed.</note><affiliation>To whom requests for reprints should be addressed.</affiliation><affiliation>Centre d'Immunologie INSERM-CNRS, de Marseille-Luminy, Case 906, 13288 Marseille Cedex 09, UK</affiliation></author><author xml:id="author-0001"><persName><forename type="first">Danièle</forename><surname>Roux</surname></persName><affiliation>Centre d'Immunologie INSERM-CNRS, de Marseille-Luminy, Case 906, 13288 Marseille Cedex 09, UK</affiliation></author><author xml:id="author-0002"><persName><forename type="first">Hélène</forename><surname>Cailla</surname></persName><affiliation>Centre d'Immunologie INSERM-CNRS, de Marseille-Luminy, Case 906, 13288 Marseille Cedex 09, UK</affiliation></author><author xml:id="author-0003"><persName><forename type="first">Yves</forename><surname>Riviere</surname></persName><affiliation>Institut Pasteur, Unité d'Oncologie Virale, 25, Rue du Dr. Roux, 75724 Paris Cedex 15, France</affiliation></author><author xml:id="author-0004"><persName><forename type="first">Rugimar</forename><surname>Marcovistz</surname></persName><affiliation>Institut Pasteur, Unité d'Oncologie Virale, 25, Rue du Dr. Roux, 75724 Paris Cedex 15, France</affiliation></author><author xml:id="author-0005"><persName><forename type="first">Ara</forename><surname>Hovanessian</surname></persName><affiliation>Institut Pasteur, Unité d'Oncologie Virale, 25, Rue du Dr. Roux, 75724 Paris Cedex 15, France</affiliation></author><idno type="istex">2DA08B6B0C4336D39B4DDE3BE46872EA36FEA904</idno><idno type="ark">ark:/67375/6H6-KPXMKMM6-X</idno><idno type="DOI">10.1016/0042-6822(85)90116-3</idno><idno type="PII">0042-6822(85)90116-3</idno></analytic><monogr><title level="j">Virology</title><title level="j" type="abbrev">YVIRO</title><idno type="pISSN">0042-6822</idno><idno type="PII">S0042-6822(00)X0330-3</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1985"></date><biblScope unit="volume">143</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="290">290</biblScope><biblScope unit="page" to="299">299</biblScope></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>1985</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Abstract: Intracellular levels of 2′,5′-adenyladenosine oligonucleotides were analyzed in different organs of mice during the course of λ rabies virus infection. Phosphorylated and nonphosphorylated 2′,5′-adenyladenosine oligonucleotides were measured by radioimmunoassay and analyzed further by HPLC. As the infection progressed, concentrations of phosphorylated 2′,5′-adenyladenosine oligonucleotides increased strongly, reaching their maxima late in the infection. In contrast, concentrations of the nonphosphorylated 2′,5′-adenyladenosine oligonucleotides decreased. A similar phenomenon was observed in spleens analyzed at intervals after treatment of noninfected mice with interferon and poly(l) · poly(C) and to λ lesser extent after treatment with poly(I) · poly(C) alone, but not after treatment with interferon alone. The products which accumulated during virus infection were primarily phosphorylated dimers whereas during combined interferon and poly(I) · poly(C) treatment, the entire range of phosphorylated molecules from dimer to pentamer was present. These data show that infection of mice with rabies virus provokes both the induction and the activation of 2–5A synthetase, as does interferon and poly(I) · poly(C) treatment. However, our data indicate that the intracellular products are different in the two situations: the species active on the nuclease were only detected in interferon- and poly(I) · poly(C)-treated mice. The absence of molecules able to activate the 2–5A-dependent nuclease in virus-infected mice might well be one of the reasons why the interferon system is ineffective in rabies virus infection.</p></abstract></profileDesc><revisionDesc><change when="1985">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/6H6-KPXMKMM6-X/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Elsevier, elements deleted: tail"><istex:xmlDeclaration>version="1.0" encoding="utf-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//ES//DTD journal article DTD version 4.5.2//EN//XML" URI="art452.dtd" name="istex:docType"></istex:docType><istex:document><converted-article version="4.5.2" docsubtype="fla"><item-info><jid>YVIRO</jid><aid>85901163</aid><ce:pii>0042-6822(85)90116-3</ce:pii><ce:doi>10.1016/0042-6822(85)90116-3</ce:doi><ce:copyright type="unknown" year="1985"></ce:copyright></item-info><head><ce:title>Comparison of the effects of rabies virus infection and of combined interferon and poly(I) · poly(C) treatment on the levels of 2′,5′-adenyladenosine oligonucleotides in different organs of mice</ce:title><ce:author-group><ce:author><ce:given-name>Liliane</ce:given-name><ce:surname>Laurence</ce:surname><ce:cross-ref refid="COR1"><ce:sup>1</ce:sup></ce:cross-ref><ce:cross-ref refid="AFF1"><ce:sup>∗∗</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Danièle</ce:given-name><ce:surname>Roux</ce:surname><ce:cross-ref refid="AFF1"><ce:sup>∗∗</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Hélène</ce:given-name><ce:surname>Cailla</ce:surname><ce:cross-ref refid="AFF1"><ce:sup>∗∗</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Yves</ce:given-name><ce:surname>Riviere</ce:surname><ce:cross-ref refid="AFF2"><ce:sup>∗</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Rugimar</ce:given-name><ce:surname>Marcovistz</ce:surname><ce:cross-ref refid="AFF2"><ce:sup>∗</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Ara</ce:given-name><ce:surname>Hovanessian</ce:surname><ce:cross-ref refid="AFF2"><ce:sup>∗</ce:sup></ce:cross-ref></ce:author><ce:affiliation id="AFF1"><ce:label>a</ce:label><ce:textfn>Centre d'Immunologie INSERM-CNRS, de Marseille-Luminy, Case 906, 13288 Marseille Cedex 09, UK</ce:textfn></ce:affiliation><ce:affiliation id="AFF2"><ce:label>b</ce:label><ce:textfn>Institut Pasteur, Unité d'Oncologie Virale, 25, Rue du Dr. Roux, 75724 Paris Cedex 15, France</ce:textfn></ce:affiliation><ce:correspondence id="COR1"><ce:label>1</ce:label><ce:text>To whom requests for reprints should be addressed.</ce:text></ce:correspondence></ce:author-group><ce:date-received day="2" month="10" year="1984"></ce:date-received><ce:date-accepted day="14" month="1" year="1985"></ce:date-accepted><ce:abstract><ce:section-title>Abstract</ce:section-title><ce:abstract-sec><ce:simple-para>Intracellular levels of 2′,5′-adenyladenosine oligonucleotides were analyzed in different organs of mice during the course of λ rabies virus infection. Phosphorylated and nonphosphorylated 2′,5′-adenyladenosine oligonucleotides were measured by radioimmunoassay and analyzed further by HPLC. As the infection progressed, concentrations of phosphorylated 2′,5′-adenyladenosine oligonucleotides increased strongly, reaching their maxima late in the infection. In contrast, concentrations of the nonphosphorylated 2′,5′-adenyladenosine oligonucleotides decreased. A similar phenomenon was observed in spleens analyzed at intervals after treatment of noninfected mice with interferon and poly(l) · poly(C) and to λ lesser extent after treatment with poly(I) · poly(C) alone, but not after treatment with interferon alone. The products which accumulated during virus infection were primarily phosphorylated dimers whereas during combined interferon and poly(I) · poly(C) treatment, the entire range of phosphorylated molecules from dimer to pentamer was present. These data show that infection of mice with rabies virus provokes both the induction and the activation of 2–5A synthetase, as does interferon and poly(I) · poly(C) treatment. However, our data indicate that the intracellular products are different in the two situations: the species active on the nuclease were only detected in interferon- and poly(I) · poly(C)-treated mice. The absence of molecules able to activate the 2–5A-dependent nuclease in virus-infected mice might well be one of the reasons why the interferon system is ineffective in rabies virus infection.</ce:simple-para></ce:abstract-sec></ce:abstract></head></converted-article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo><title>Comparison of the effects of rabies virus infection and of combined interferon and poly(I) · poly(C) treatment on the levels of 2′,5′-adenyladenosine oligonucleotides in different organs of mice</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Comparison of the effects of rabies virus infection and of combined interferon and poly(I) · poly(C) treatment on the levels of 2′,5′-adenyladenosine oligonucleotides in different organs of mice</title></titleInfo><name type="personal"><namePart type="given">Liliane</namePart><namePart type="family">Laurence</namePart><affiliation>Centre d'Immunologie INSERM-CNRS, de Marseille-Luminy, Case 906, 13288 Marseille Cedex 09, UK</affiliation><description>To whom requests for reprints should be addressed.</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Danièle</namePart><namePart type="family">Roux</namePart><affiliation>Centre d'Immunologie INSERM-CNRS, de Marseille-Luminy, Case 906, 13288 Marseille Cedex 09, UK</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Hélène</namePart><namePart type="family">Cailla</namePart><affiliation>Centre d'Immunologie INSERM-CNRS, de Marseille-Luminy, Case 906, 13288 Marseille Cedex 09, UK</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Yves</namePart><namePart type="family">Riviere</namePart><affiliation>Institut Pasteur, Unité d'Oncologie Virale, 25, Rue du Dr. Roux, 75724 Paris Cedex 15, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Rugimar</namePart><namePart type="family">Marcovistz</namePart><affiliation>Institut Pasteur, Unité d'Oncologie Virale, 25, Rue du Dr. Roux, 75724 Paris Cedex 15, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Ara</namePart><namePart type="family">Hovanessian</namePart><affiliation>Institut Pasteur, Unité d'Oncologie Virale, 25, Rue du Dr. Roux, 75724 Paris Cedex 15, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="Full-length article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">1985</dateIssued><copyrightDate encoding="w3cdtf">1985</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><abstract lang="en">Abstract: Intracellular levels of 2′,5′-adenyladenosine oligonucleotides were analyzed in different organs of mice during the course of λ rabies virus infection. Phosphorylated and nonphosphorylated 2′,5′-adenyladenosine oligonucleotides were measured by radioimmunoassay and analyzed further by HPLC. As the infection progressed, concentrations of phosphorylated 2′,5′-adenyladenosine oligonucleotides increased strongly, reaching their maxima late in the infection. In contrast, concentrations of the nonphosphorylated 2′,5′-adenyladenosine oligonucleotides decreased. A similar phenomenon was observed in spleens analyzed at intervals after treatment of noninfected mice with interferon and poly(l) · poly(C) and to λ lesser extent after treatment with poly(I) · poly(C) alone, but not after treatment with interferon alone. The products which accumulated during virus infection were primarily phosphorylated dimers whereas during combined interferon and poly(I) · poly(C) treatment, the entire range of phosphorylated molecules from dimer to pentamer was present. These data show that infection of mice with rabies virus provokes both the induction and the activation of 2–5A synthetase, as does interferon and poly(I) · poly(C) treatment. However, our data indicate that the intracellular products are different in the two situations: the species active on the nuclease were only detected in interferon- and poly(I) · poly(C)-treated mice. The absence of molecules able to activate the 2–5A-dependent nuclease in virus-infected mice might well be one of the reasons why the interferon system is ineffective in rabies virus infection.</abstract><relatedItem type="host"><titleInfo><title>Virology</title></titleInfo><titleInfo type="abbreviated"><title>YVIRO</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">1985</dateIssued></originInfo><identifier type="ISSN">0042-6822</identifier><identifier type="PII">S0042-6822(00)X0330-3</identifier><part><date>1985</date><detail type="volume"><number>143</number><caption>vol.</caption></detail><detail type="issue"><number>1</number><caption>no.</caption></detail><extent unit="issue-pages"><start>1</start><end>358</end></extent><extent unit="pages"><start>290</start><end>299</end></extent></part></relatedItem><identifier type="istex">2DA08B6B0C4336D39B4DDE3BE46872EA36FEA904</identifier><identifier type="ark">ark:/67375/6H6-KPXMKMM6-X</identifier><identifier type="DOI">10.1016/0042-6822(85)90116-3</identifier><identifier type="PII">0042-6822(85)90116-3</identifier><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-HKKZVM7B-M">elsevier</recordContentSource></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/ark:/67375/6H6-KPXMKMM6-X/record.json</uri></json:item></metadata></istex></record>Pour manipuler ce document sous Unix (Dilib)
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