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Acute obstructive parasternal lymphedema produced in rats without surgery.

Identifieur interne : 005C53 ( PubMed/Curation ); précédent : 005C52; suivant : 005C54

Acute obstructive parasternal lymphedema produced in rats without surgery.

Auteurs : S. Levine ; A. Saltzman

Source :

Lymphology [ 0024-7766 ] ; 1990.

RBID : pubmed:2127616

Descripteurs français

KwdFr :
- Animaux, Déformabilité érythrocytaire, Femelle, Glutaraldéhyde (pharmacologie), Lymphoedème (anatomopathologie), Lymphoedème (étiologie), Maladies du thorax (anatomopathologie), Maladies du thorax (étiologie), Mâle, Noeuds lymphatiques (anatomopathologie), Rats, Rats de lignée LEW, Tissu conjonctif (anatomopathologie), Érythrocytes.
MESH :
- anatomopathologie : Lymphoedème, Maladies du thorax, Noeuds lymphatiques, Tissu conjonctif.
- pharmacologie : Glutaraldéhyde.
- étiologie : Lymphoedème, Maladies du thorax.
- Animaux, Déformabilité érythrocytaire, Femelle, Mâle, Rats, Rats de lignée LEW, Érythrocytes.

English descriptors

KwdEn :
- Animals, Connective Tissue (pathology), Erythrocyte Deformability, Erythrocytes, Female, Glutaral (pharmacology), Lymph Nodes (pathology), Lymphedema (etiology), Lymphedema (pathology), Male, Rats, Rats, Inbred Lew, Thoracic Diseases (etiology), Thoracic Diseases (pathology).
MESH :
- chemical , pharmacology : Glutaral.
- etiology : Lymphedema, Thoracic Diseases.
- pathology : Connective Tissue, Lymph Nodes, Lymphedema, Thoracic Diseases.
- Animals, Erythrocyte Deformability, Erythrocytes, Female, Male, Rats, Rats, Inbred Lew.

Abstract

Although rat red blood cells (RBC) were altered by pretreatment with glutaraldehyde, they nonetheless were well absorbed into mediastinal lymphatics of Lewis rats after intraperitoneal injection. Unlike normal RBC, they did not pass freely through the draining mediastinal lymph nodes. Instead, clumps of free and phagocytosed glutaraldehyde-treated RBC distended and obstructed the afferent lymphatics and the sinuses of draining lymph nodes. The lymphatic obstruction caused edema in a clearly defined compartment of fatty connective tissue between the muscle layers of the ventral chest wall. The obstructive lymphedema interfered with the immunizing effect of small doses of sheep RBC injected intraperitoneally. This study emphasizes the potential utility of the rat's mediastinal lymphatics for studies of lymphatic leakage and obstruction.

PubMed: 2127616

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S. Levine

<affiliation><nlm:affiliation>Department of Pathology, New York Medical College, Valhalla.</nlm:affiliation>
<wicri:noCountry code="subField">Valhalla</wicri:noCountry>
</affiliation>

Le document en format XML

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<term>Maladies du thorax (étiologie)</term>
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<term>Noeuds lymphatiques (anatomopathologie)</term>
<term>Rats</term>
<term>Rats de lignée LEW</term>
<term>Tissu conjonctif (anatomopathologie)</term>
<term>Érythrocytes</term>
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<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Glutaral</term>
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<term>Maladies du thorax</term>
<term>Noeuds lymphatiques</term>
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<term>Maladies du thorax</term>
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<term>Erythrocyte Deformability</term>
<term>Erythrocytes</term>
<term>Female</term>
<term>Male</term>
<term>Rats</term>
<term>Rats, Inbred Lew</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Déformabilité érythrocytaire</term>
<term>Femelle</term>
<term>Mâle</term>
<term>Rats</term>
<term>Rats de lignée LEW</term>
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<front><div type="abstract" xml:lang="en">Although rat red blood cells (RBC) were altered by pretreatment with glutaraldehyde, they nonetheless were well absorbed into mediastinal lymphatics of Lewis rats after intraperitoneal injection. Unlike normal RBC, they did not pass freely through the draining mediastinal lymph nodes. Instead, clumps of free and phagocytosed glutaraldehyde-treated RBC distended and obstructed the afferent lymphatics and the sinuses of draining lymph nodes. The lymphatic obstruction caused edema in a clearly defined compartment of fatty connective tissue between the muscle layers of the ventral chest wall. The obstructive lymphedema interfered with the immunizing effect of small doses of sheep RBC injected intraperitoneally. This study emphasizes the potential utility of the rat's mediastinal lymphatics for studies of lymphatic leakage and obstruction.</div>
</front>
</TEI>
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<Title>Lymphology</Title>
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<Abstract><AbstractText>Although rat red blood cells (RBC) were altered by pretreatment with glutaraldehyde, they nonetheless were well absorbed into mediastinal lymphatics of Lewis rats after intraperitoneal injection. Unlike normal RBC, they did not pass freely through the draining mediastinal lymph nodes. Instead, clumps of free and phagocytosed glutaraldehyde-treated RBC distended and obstructed the afferent lymphatics and the sinuses of draining lymph nodes. The lymphatic obstruction caused edema in a clearly defined compartment of fatty connective tissue between the muscle layers of the ventral chest wall. The obstructive lymphedema interfered with the immunizing effect of small doses of sheep RBC injected intraperitoneally. This study emphasizes the potential utility of the rat's mediastinal lymphatics for studies of lymphatic leakage and obstruction.</AbstractText>
</Abstract>
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Acute obstructive parasternal lymphedema produced in rats without surgery.

Acute obstructive parasternal lymphedema produced in rats without surgery.

Source :

Descripteurs français

English descriptors

Abstract

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Links to Exploration step

Curation

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Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki