Adverse reactions following mass drug administration with diethylcarbamazine in lymphatic filariasis endemic areas in the Northeast of Brazil.
Identifieur interne : 001D64 ( PubMed/Curation ); précédent : 001D63; suivant : 001D65Adverse reactions following mass drug administration with diethylcarbamazine in lymphatic filariasis endemic areas in the Northeast of Brazil.
Auteurs : Ana Wládia Lima [Brésil] ; Zulma Medeiros ; Zailde Carvalho Dos Santos ; Gertrudes Monteiro Da Costa ; Cynthia BragaSource :
- Revista da Sociedade Brasileira de Medicina Tropical [ 1678-9849 ] ; 2012.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Animaux, Brésil (épidémiologie), Diéthylcarbamazine (administration et posologie), Diéthylcarbamazine (effets indésirables), Femelle, Filaricides (administration et posologie), Filaricides (effets indésirables), Filariose lymphatique (traitement médicamenteux), Filariose lymphatique (épidémiologie), Humains, Jeune adulte, Maladies endémiques, Mâle, Prévalence, Études transversales.
- MESH :
- administration et posologie : Diéthylcarbamazine, Filaricides.
- effets indésirables : Diéthylcarbamazine, Filaricides.
- traitement médicamenteux : Filariose lymphatique.
- épidémiologie : Brésil, Filariose lymphatique.
- Adolescent, Adulte, Animaux, Femelle, Humains, Jeune adulte, Maladies endémiques, Mâle, Prévalence, Études transversales.
- Wicri :
- geographic : Brésil.
English descriptors
- KwdEn :
- Adolescent, Adult, Animals, Brazil (epidemiology), Cross-Sectional Studies, Diethylcarbamazine (administration & dosage), Diethylcarbamazine (adverse effects), Elephantiasis, Filarial (drug therapy), Elephantiasis, Filarial (epidemiology), Endemic Diseases, Female, Filaricides (administration & dosage), Filaricides (adverse effects), Humans, Male, Prevalence, Young Adult.
- MESH :
- chemical , administration & dosage : Diethylcarbamazine, Filaricides.
- chemical , adverse effects : Diethylcarbamazine, Filaricides.
- geographic , epidemiology : Brazil.
- drug therapy : Elephantiasis, Filarial.
- epidemiology : Elephantiasis, Filarial.
- Adolescent, Adult, Animals, Cross-Sectional Studies, Endemic Diseases, Female, Humans, Male, Prevalence, Young Adult.
Abstract
The Global Programme to Eliminate Lymphatic Filariasis was launched with the goal of eliminating this disease via the annual mass drug administration (MDA) of a single dose of antifilarial drugs. Adverse drug reactions following MDA are a major factor of poor treatment adherence in several countries. This study assessed the occurrence of adverse drug reactions (ADRs) following the first round of mass treatment in two communities treated with different dosages of diethylcarbamazine (DEC) in the City of Recife, Brazil.
PubMed: 23295880
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Gertrudes Monteiro Da" uniqKey="Costa G" first="Gertrudes Monteiro Da" last="Costa">Gertrudes Monteiro Da Costa</name></author><author><name sortKey="Braga, Cynthia" sort="Braga, Cynthia" uniqKey="Braga C" first="Cynthia" last="Braga">Cynthia Braga</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2012">2012</date><idno type="RBID">pubmed:23295880</idno><idno type="pmid">23295880</idno><idno type="wicri:Area/PubMed/Corpus">001D64</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001D64</idno><idno type="wicri:Area/PubMed/Curation">001D64</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001D64</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Adverse reactions following mass drug administration with diethylcarbamazine in lymphatic filariasis endemic areas in the Northeast of Brazil.</title><author><name sortKey="Lima, Ana Wladia" sort="Lima, Ana Wladia" uniqKey="Lima A" first="Ana Wládia" last="Lima">Ana Wládia Lima</name><affiliation wicri:level="1"><nlm:affiliation>Centro Acadêmico de Vitória, Universidade Federal de Pernambuco, Vitória de Santo Antão, PE. anwladia@bol.com.br</nlm:affiliation><country wicri:rule="url">Brésil</country></affiliation></author><author><name sortKey="Medeiros, Zulma" sort="Medeiros, Zulma" uniqKey="Medeiros Z" first="Zulma" last="Medeiros">Zulma Medeiros</name></author><author><name sortKey="Santos, Zailde Carvalho Dos" sort="Santos, Zailde Carvalho Dos" uniqKey="Santos Z" first="Zailde Carvalho Dos" last="Santos">Zailde Carvalho Dos Santos</name></author><author><name sortKey="Costa, Gertrudes Monteiro Da" sort="Costa, Gertrudes Monteiro Da" uniqKey="Costa G" first="Gertrudes Monteiro Da" last="Costa">Gertrudes Monteiro Da Costa</name></author><author><name sortKey="Braga, Cynthia" sort="Braga, Cynthia" uniqKey="Braga C" first="Cynthia" last="Braga">Cynthia Braga</name></author></analytic><series><title level="j">Revista da Sociedade Brasileira de Medicina Tropical</title><idno type="eISSN">1678-9849</idno><imprint><date when="2012" type="published">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Animals</term><term>Brazil (epidemiology)</term><term>Cross-Sectional Studies</term><term>Diethylcarbamazine (administration & dosage)</term><term>Diethylcarbamazine (adverse effects)</term><term>Elephantiasis, Filarial (drug therapy)</term><term>Elephantiasis, Filarial (epidemiology)</term><term>Endemic Diseases</term><term>Female</term><term>Filaricides (administration & dosage)</term><term>Filaricides (adverse effects)</term><term>Humans</term><term>Male</term><term>Prevalence</term><term>Young Adult</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Animaux</term><term>Brésil (épidémiologie)</term><term>Diéthylcarbamazine (administration et posologie)</term><term>Diéthylcarbamazine (effets indésirables)</term><term>Femelle</term><term>Filaricides (administration et posologie)</term><term>Filaricides (effets indésirables)</term><term>Filariose lymphatique (traitement médicamenteux)</term><term>Filariose lymphatique (épidémiologie)</term><term>Humains</term><term>Jeune adulte</term><term>Maladies endémiques</term><term>Mâle</term><term>Prévalence</term><term>Études transversales</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Diethylcarbamazine</term><term>Filaricides</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Diethylcarbamazine</term><term>Filaricides</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Brazil</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Diéthylcarbamazine</term><term>Filaricides</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Elephantiasis, Filarial</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Diéthylcarbamazine</term><term>Filaricides</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Elephantiasis, Filarial</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Filariose lymphatique</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Brésil</term><term>Filariose lymphatique</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Animals</term><term>Cross-Sectional Studies</term><term>Endemic Diseases</term><term>Female</term><term>Humans</term><term>Male</term><term>Prevalence</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Animaux</term><term>Femelle</term><term>Humains</term><term>Jeune adulte</term><term>Maladies endémiques</term><term>Mâle</term><term>Prévalence</term><term>Études transversales</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Brésil</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The Global Programme to Eliminate Lymphatic Filariasis was launched with the goal of eliminating this disease via the annual mass drug administration (MDA) of a single dose of antifilarial drugs. Adverse drug reactions following MDA are a major factor of poor treatment adherence in several countries. This study assessed the occurrence of adverse drug reactions (ADRs) following the first round of mass treatment in two communities treated with different dosages of diethylcarbamazine (DEC) in the City of Recife, Brazil.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">23295880</PMID><DateCreated><Year>2013</Year><Month>01</Month><Day>08</Day></DateCreated><DateCompleted><Year>2013</Year><Month>07</Month><Day>25</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1678-9849</ISSN><JournalIssue CitedMedium="Internet"><Volume>45</Volume><Issue>6</Issue><PubDate><Year>2012</Year><Month>Dec</Month></PubDate></JournalIssue><Title>Revista da Sociedade Brasileira de Medicina Tropical</Title><ISOAbbreviation>Rev. Soc. Bras. Med. Trop.</ISOAbbreviation></Journal><ArticleTitle>Adverse reactions following mass drug administration with diethylcarbamazine in lymphatic filariasis endemic areas in the Northeast of Brazil.</ArticleTitle><Pagination><MedlinePgn>745-50</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0037-86822012000600017</ELocationID><Abstract><AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">The Global Programme to Eliminate Lymphatic Filariasis was launched with the goal of eliminating this disease via the annual mass drug administration (MDA) of a single dose of antifilarial drugs. Adverse drug reactions following MDA are a major factor of poor treatment adherence in several countries. This study assessed the occurrence of adverse drug reactions (ADRs) following the first round of mass treatment in two communities treated with different dosages of diethylcarbamazine (DEC) in the City of Recife, Brazil.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Population-based cross-sectional surveys were conducted in a random sample of the population living in both communities (Areas I and II). The dose of DEC recommended by the WHO (6mg/kg) was calculated based on the individual's weight-for-age. In Area II, weight differences between the genders were also considered when determining dosage. Data were obtained through interviews conducted in the first 12 to 48h and on the 5th day after MDA during household visits.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">A total of 487 and 365 individuals were interviewed in Areas I and II, respectively. The prevalence of ADRs in Area I (23.6; 95%CI: 19.1-29.5) was higher than in Area II (16.2; 95%CI:11.9-21.5)(p=0.0078). The prevalence of ADRs among females was higher than in males in Area I (p=0.0021). In Area II, no significant difference between the genders was observed (p=0.1840). Age was not associated with ADRs in either area.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Adjusting MDA dosage schedules according to weight-for-age and sex may be may contribute to reduce the occurrence of adverse drug reactions in the population.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Lima</LastName><ForeName>Ana Wládia</ForeName><Initials>AW</Initials><AffiliationInfo><Affiliation>Centro Acadêmico de Vitória, Universidade Federal de Pernambuco, Vitória de Santo Antão, PE. anwladia@bol.com.br</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Medeiros</LastName><ForeName>Zulma</ForeName><Initials>Z</Initials></Author><Author ValidYN="Y"><LastName>Santos</LastName><ForeName>Zailde Carvalho Dos</ForeName><Initials>ZC</Initials></Author><Author ValidYN="Y"><LastName>Costa</LastName><ForeName>Gertrudes Monteiro da</ForeName><Initials>GM</Initials></Author><Author ValidYN="Y"><LastName>Braga</LastName><ForeName>Cynthia</ForeName><Initials>C</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Brazil</Country><MedlineTA>Rev Soc Bras Med Trop</MedlineTA><NlmUniqueID>7507456</NlmUniqueID><ISSNLinking>0037-8682</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D005369">Filaricides</NameOfSubstance></Chemical><Chemical><RegistryNumber>V867Q8X3ZD</RegistryNumber><NameOfSubstance UI="D004049">Diethylcarbamazine</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001938" MajorTopicYN="N" Type="Geographic">Brazil</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003430" MajorTopicYN="N">Cross-Sectional Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004049" MajorTopicYN="N">Diethylcarbamazine</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000009" MajorTopicYN="Y">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004605" MajorTopicYN="N">Elephantiasis, Filarial</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D019353" MajorTopicYN="N">Endemic Diseases</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005369" MajorTopicYN="N">Filaricides</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000009" MajorTopicYN="Y">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015995" MajorTopicYN="N">Prevalence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2012</Year><Month>02</Month><Day>14</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2012</Year><Month>10</Month><Day>23</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2013</Year><Month>1</Month><Day>9</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2013</Year><Month>1</Month><Day>9</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2013</Year><Month>7</Month><Day>26</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">23295880</ArticleId><ArticleId IdType="pii">S0037-86822012000600017</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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