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The relationship of body mass index with quality of life among endometrial cancer survivors: a study from the population-based PROFILES registry.

Identifieur interne : 001D63 ( PubMed/Curation ); précédent : 001D62; suivant : 001D64

The relationship of body mass index with quality of life among endometrial cancer survivors: a study from the population-based PROFILES registry.

Auteurs : Charlotte S. Oldenburg [Pays-Bas] ; Dorry Boll ; Kim A H. Nicolaije ; M Caroline Vos ; Johanna M A. Pijnenborg ; Jan-Willem Coebergh ; Sandra Beijer ; Lonneke V. Van De Poll-Franse ; Nicole P M. Ezendam

Source :

RBID : pubmed:23296262

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Abstract

The aim of the study was to assess the association of body mass index (BMI) and Health-Related Quality of Life (HRQoL), and the relative importance of BMI in explaining variation in QoL among stage I or II endometrial cancer (EC), independent of comorbidities, socio-demographic and clinical characteristics.

DOI: 10.1016/j.ygyno.2012.12.041
PubMed: 23296262

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pubmed:23296262

Le document en format XML

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<title xml:lang="en">The relationship of body mass index with quality of life among endometrial cancer survivors: a study from the population-based PROFILES registry.</title>
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<name sortKey="Oldenburg, Charlotte S" sort="Oldenburg, Charlotte S" uniqKey="Oldenburg C" first="Charlotte S" last="Oldenburg">Charlotte S. Oldenburg</name>
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<nlm:affiliation>Comprehensive Cancer Center South, Eindhoven Cancer Registry, Eindhoven, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Comprehensive Cancer Center South, Eindhoven Cancer Registry, Eindhoven</wicri:regionArea>
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<name sortKey="Boll, Dorry" sort="Boll, Dorry" uniqKey="Boll D" first="Dorry" last="Boll">Dorry Boll</name>
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<name sortKey="Nicolaije, Kim A H" sort="Nicolaije, Kim A H" uniqKey="Nicolaije K" first="Kim A H" last="Nicolaije">Kim A H. Nicolaije</name>
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<name sortKey="Vos, M Caroline" sort="Vos, M Caroline" uniqKey="Vos M" first="M Caroline" last="Vos">M Caroline Vos</name>
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<name sortKey="Pijnenborg, Johanna M A" sort="Pijnenborg, Johanna M A" uniqKey="Pijnenborg J" first="Johanna M A" last="Pijnenborg">Johanna M A. Pijnenborg</name>
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<name sortKey="Coebergh, Jan Willem" sort="Coebergh, Jan Willem" uniqKey="Coebergh J" first="Jan-Willem" last="Coebergh">Jan-Willem Coebergh</name>
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<name sortKey="Beijer, Sandra" sort="Beijer, Sandra" uniqKey="Beijer S" first="Sandra" last="Beijer">Sandra Beijer</name>
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<name sortKey="Van De Poll Franse, Lonneke V" sort="Van De Poll Franse, Lonneke V" uniqKey="Van De Poll Franse L" first="Lonneke V" last="Van De Poll-Franse">Lonneke V. Van De Poll-Franse</name>
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<title level="j">Gynecologic oncology</title>
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<term>Adult</term>
<term>Aged</term>
<term>Body Mass Index</term>
<term>Cross-Sectional Studies</term>
<term>Endometrial Neoplasms (pathology)</term>
<term>Endometrial Neoplasms (psychology)</term>
<term>Female</term>
<term>Humans</term>
<term>Middle Aged</term>
<term>Neoplasm Staging</term>
<term>Quality of Life</term>
<term>Registries</term>
<term>Survivors</term>
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<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Enregistrements</term>
<term>Femelle</term>
<term>Humains</term>
<term>Indice de masse corporelle</term>
<term>Qualité de vie</term>
<term>Stade de la tumeur</term>
<term>Sujet âgé</term>
<term>Survivants</term>
<term>Tumeurs de l'endomètre (anatomopathologie)</term>
<term>Tumeurs de l'endomètre (psychologie)</term>
<term>Études transversales</term>
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<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr">
<term>Tumeurs de l'endomètre</term>
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<keywords scheme="MESH" qualifier="pathology" xml:lang="en">
<term>Endometrial Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="psychologie" xml:lang="fr">
<term>Tumeurs de l'endomètre</term>
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<term>Endometrial Neoplasms</term>
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<term>Aged</term>
<term>Body Mass Index</term>
<term>Cross-Sectional Studies</term>
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<term>Humans</term>
<term>Middle Aged</term>
<term>Neoplasm Staging</term>
<term>Quality of Life</term>
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<term>Survivors</term>
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<term>Adulte d'âge moyen</term>
<term>Enregistrements</term>
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<term>Indice de masse corporelle</term>
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<front>
<div type="abstract" xml:lang="en">The aim of the study was to assess the association of body mass index (BMI) and Health-Related Quality of Life (HRQoL), and the relative importance of BMI in explaining variation in QoL among stage I or II endometrial cancer (EC), independent of comorbidities, socio-demographic and clinical characteristics.</div>
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<DateCreated>
<Year>2013</Year>
<Month>03</Month>
<Day>25</Day>
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<DateCompleted>
<Year>2013</Year>
<Month>05</Month>
<Day>13</Day>
</DateCompleted>
<DateRevised>
<Year>2013</Year>
<Month>03</Month>
<Day>25</Day>
</DateRevised>
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<ISSN IssnType="Electronic">1095-6859</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>129</Volume>
<Issue>1</Issue>
<PubDate>
<Year>2013</Year>
<Month>Apr</Month>
</PubDate>
</JournalIssue>
<Title>Gynecologic oncology</Title>
<ISOAbbreviation>Gynecol. Oncol.</ISOAbbreviation>
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<ArticleTitle>The relationship of body mass index with quality of life among endometrial cancer survivors: a study from the population-based PROFILES registry.</ArticleTitle>
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<MedlinePgn>216-21</MedlinePgn>
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<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.ygyno.2012.12.041</ELocationID>
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<Abstract>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">The aim of the study was to assess the association of body mass index (BMI) and Health-Related Quality of Life (HRQoL), and the relative importance of BMI in explaining variation in QoL among stage I or II endometrial cancer (EC), independent of comorbidities, socio-demographic and clinical characteristics.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">A population-based, cross-sectional survey was conducted in 2008 among endometrial cancer survivors diagnosed between 1999 and 2007 sampled from the Eindhoven Cancer Registry. The HRQoL (SF-36), EC specific HRQoL (EORTC-QLQ-EN24), comorbidities (SCQ) and fatigue (FAS) questionnaire were completed by 666 endometrioid EC survivors. Multivariate regression analyses were used to assess the associations of HRQoL with BMI reported at time of questionnaire completion and to assess the percentage of variance in HRQoL outcomes explained by BMI (R(2)), (controlled for socio-demographic and clinical characteristics and comorbidity).</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Of all women, 432 (67.6%) were pre-obese (BMI 25-30) or obese (BMI >30). Increased BMI was associated with decreased physical function, decreased vitality, more lymphoedema symptoms, decreased sexual/vaginal problems, less taste change and more fatigue symptoms. BMI added significantly to the explained variance of physical function (4.3%), physical limitations in daily life (role physical; 0.7%), bodily pain (1.5%), vitality (1.6%), emotional limitations in daily life (role emotional; 0.9%), lymphoedema symptoms (5.2%), sexual/vaginal problems (3.2%), urologic problems (0.7%), and fatigue (1.4%).</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">BMI was related to several HRQoL outcomes. Therefore BMI needs to be taken into account in HRQoL studies. Moreover, future research should assess if interventions to decrease BMI in obese EC survivors might improve HRQoL.</AbstractText>
<CopyrightInformation>Copyright © 2013 Elsevier Inc. All rights reserved.</CopyrightInformation>
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<LastName>Oldenburg</LastName>
<ForeName>Charlotte S</ForeName>
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<DescriptorName UI="D011788" MajorTopicYN="Y">Quality of Life</DescriptorName>
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