Perceptive solutions to anti-filarial chemotherapy of lymphatic filariasis from the plethora of nanomedical sciences.
Identifieur interne : 001943 ( PubMed/Corpus ); précédent : 001942; suivant : 001944Perceptive solutions to anti-filarial chemotherapy of lymphatic filariasis from the plethora of nanomedical sciences.
Auteurs : Mohammad Ali ; Mohammad Afzal ; Ujjwal Kaushik ; Shailja Mishra Bhattacharya ; Farhan Jalees Ahmad ; Amit Kumar DindaSource :
- Journal of drug targeting [ 1029-2330 ] ; 2014.
English descriptors
- KwdEn :
- MESH :
- chemical , pharmacokinetics : Filaricides.
- drug therapy : Elephantiasis, Filarial.
- methods : Drug Delivery Systems.
- chemical , pharmacology : Filaricides.
- chemical , therapeutic use : Filaricides.
- Animals, Humans.
Abstract
Growing interest in the application of nanotechnology to treat lymphatic filariasis (LF) implies that the imminent medical arsenal of this interesting technology is attractive for health authorities. Currently, they are completely dependent on friendly oral mass drug (anti-filarials) administration to eliminate this morbid disease and are now looking for new alternatives to bring about further improvements.
DOI: 10.3109/1061186X.2013.832766
PubMed: 24004100
Links to Exploration step
pubmed:24004100Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Perceptive solutions to anti-filarial chemotherapy of lymphatic filariasis from the plethora of nanomedical sciences.</title><author><name sortKey="Ali, Mohammad" sort="Ali, Mohammad" uniqKey="Ali M" first="Mohammad" last="Ali">Mohammad Ali</name><affiliation><nlm:affiliation>Nanomedicine Lab, Faculty of Engineering & Interdisciplinary Sciences, Hamdard Nanobiotechnology Center for Advance Research, Hamdard University (Jamia Hamdard) , New Delhi -- 110062 , India .</nlm:affiliation></affiliation></author><author><name sortKey="Afzal, Mohammad" sort="Afzal, Mohammad" uniqKey="Afzal M" first="Mohammad" last="Afzal">Mohammad Afzal</name></author><author><name sortKey="Kaushik, Ujjwal" sort="Kaushik, Ujjwal" uniqKey="Kaushik U" first="Ujjwal" last="Kaushik">Ujjwal Kaushik</name></author><author><name sortKey="Bhattacharya, Shailja Mishra" sort="Bhattacharya, Shailja Mishra" uniqKey="Bhattacharya S" first="Shailja Mishra" last="Bhattacharya">Shailja Mishra Bhattacharya</name></author><author><name sortKey="Ahmad, Farhan Jalees" sort="Ahmad, Farhan Jalees" uniqKey="Ahmad F" first="Farhan Jalees" last="Ahmad">Farhan Jalees Ahmad</name></author><author><name sortKey="Dinda, Amit Kumar" sort="Dinda, Amit Kumar" uniqKey="Dinda A" first="Amit Kumar" last="Dinda">Amit Kumar Dinda</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="RBID">pubmed:24004100</idno><idno type="pmid">24004100</idno><idno type="doi">10.3109/1061186X.2013.832766</idno><idno type="wicri:Area/PubMed/Corpus">001943</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001943</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Perceptive solutions to anti-filarial chemotherapy of lymphatic filariasis from the plethora of nanomedical sciences.</title><author><name sortKey="Ali, Mohammad" sort="Ali, Mohammad" uniqKey="Ali M" first="Mohammad" last="Ali">Mohammad Ali</name><affiliation><nlm:affiliation>Nanomedicine Lab, Faculty of Engineering & Interdisciplinary Sciences, Hamdard Nanobiotechnology Center for Advance Research, Hamdard University (Jamia Hamdard) , New Delhi -- 110062 , India .</nlm:affiliation></affiliation></author><author><name sortKey="Afzal, Mohammad" sort="Afzal, Mohammad" uniqKey="Afzal M" first="Mohammad" last="Afzal">Mohammad Afzal</name></author><author><name sortKey="Kaushik, Ujjwal" sort="Kaushik, Ujjwal" uniqKey="Kaushik U" first="Ujjwal" last="Kaushik">Ujjwal Kaushik</name></author><author><name sortKey="Bhattacharya, Shailja Mishra" sort="Bhattacharya, Shailja Mishra" uniqKey="Bhattacharya S" first="Shailja Mishra" last="Bhattacharya">Shailja Mishra Bhattacharya</name></author><author><name sortKey="Ahmad, Farhan Jalees" sort="Ahmad, Farhan Jalees" uniqKey="Ahmad F" first="Farhan Jalees" last="Ahmad">Farhan Jalees Ahmad</name></author><author><name sortKey="Dinda, Amit Kumar" sort="Dinda, Amit Kumar" uniqKey="Dinda A" first="Amit Kumar" last="Dinda">Amit Kumar Dinda</name></author></analytic><series><title level="j">Journal of drug targeting</title><idno type="eISSN">1029-2330</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Drug Delivery Systems (methods)</term><term>Elephantiasis, Filarial (drug therapy)</term><term>Filaricides (pharmacokinetics)</term><term>Filaricides (pharmacology)</term><term>Filaricides (therapeutic use)</term><term>Humans</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacokinetics" xml:lang="en"><term>Filaricides</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Elephantiasis, Filarial</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Drug Delivery Systems</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Filaricides</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Filaricides</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Humans</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Growing interest in the application of nanotechnology to treat lymphatic filariasis (LF) implies that the imminent medical arsenal of this interesting technology is attractive for health authorities. Currently, they are completely dependent on friendly oral mass drug (anti-filarials) administration to eliminate this morbid disease and are now looking for new alternatives to bring about further improvements.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">24004100</PMID><DateCreated><Year>2013</Year><Month>12</Month><Day>09</Day></DateCreated><DateCompleted><Year>2014</Year><Month>07</Month><Day>21</Day></DateCompleted><DateRevised><Year>2013</Year><Month>12</Month><Day>09</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1029-2330</ISSN><JournalIssue CitedMedium="Internet"><Volume>22</Volume><Issue>1</Issue><PubDate><Year>2014</Year><Month>Jan</Month></PubDate></JournalIssue><Title>Journal of drug targeting</Title><ISOAbbreviation>J Drug Target</ISOAbbreviation></Journal><ArticleTitle>Perceptive solutions to anti-filarial chemotherapy of lymphatic filariasis from the plethora of nanomedical sciences.</ArticleTitle><Pagination><MedlinePgn>1-13</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.3109/1061186X.2013.832766</ELocationID><Abstract><AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">Growing interest in the application of nanotechnology to treat lymphatic filariasis (LF) implies that the imminent medical arsenal of this interesting technology is attractive for health authorities. Currently, they are completely dependent on friendly oral mass drug (anti-filarials) administration to eliminate this morbid disease and are now looking for new alternatives to bring about further improvements.</AbstractText><AbstractText Label="AREAS COVERED" NlmCategory="METHODS">A plethora of issues affecting the oral bioavailability of the mainstay human lymphatic filarial drugs, leading to meager pharmacokinetics and pharmacodynamics issues in anti-filarial chemotherapy are identified. Various important nanomedical drug delivery systems are highlighted and their solutions provided. A conceptual resolution to strictly arrest the transmission of LF in endemic areas is also presented.</AbstractText><AbstractText Label="FUTURE PERSPECTIVES" NlmCategory="CONCLUSIONS">Unless the solutions for pharmacokinetic tribulations and the measurement of factual pharmacodynamic endpoints for the existing anti-filarial drugs are evaluated using relevant approaches, health authorities will not be able to devise optimal treatment regimens for affected patients. Contemporary therapeutic paradigms need to be shifted toward the upcoming schemes of nanopharmaceutical sciences, which have enormous potential to advance the community-directed management of this tropical disease by improving the pharmacokinetic and pharmacodynamic properties of the filaricidal agents.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ali</LastName><ForeName>Mohammad</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Nanomedicine Lab, Faculty of Engineering & Interdisciplinary Sciences, Hamdard Nanobiotechnology Center for Advance Research, Hamdard University (Jamia Hamdard) , New Delhi -- 110062 , India .</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Afzal</LastName><ForeName>Mohammad</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Kaushik</LastName><ForeName>Ujjwal</ForeName><Initials>U</Initials></Author><Author ValidYN="Y"><LastName>Bhattacharya</LastName><ForeName>Shailja Mishra</ForeName><Initials>SM</Initials></Author><Author ValidYN="Y"><LastName>Ahmad</LastName><ForeName>Farhan Jalees</ForeName><Initials>FJ</Initials></Author><Author ValidYN="Y"><LastName>Dinda</LastName><ForeName>Amit Kumar</ForeName><Initials>AK</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2013</Year><Month>09</Month><Day>05</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>J Drug Target</MedlineTA><NlmUniqueID>9312476</NlmUniqueID><ISSNLinking>1026-7158</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D005369">Filaricides</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016503" MajorTopicYN="N">Drug Delivery Systems</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004605" MajorTopicYN="N">Elephantiasis, Filarial</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005369" MajorTopicYN="N">Filaricides</DescriptorName><QualifierName UI="Q000493" MajorTopicYN="N">pharmacokinetics</QualifierName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2013</Year><Month>9</Month><Day>6</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2013</Year><Month>9</Month><Day>6</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2014</Year><Month>7</Month><Day>22</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">24004100</ArticleId><ArticleId IdType="doi">10.3109/1061186X.2013.832766</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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