Lymphangiogenesis and Lymphangiogenic Growth Factors.
Identifieur interne : 001056 ( PubMed/Corpus ); précédent : 001055; suivant : 001057Lymphangiogenesis and Lymphangiogenic Growth Factors.
Auteurs : Pauliina Hartiala ; Anne M. SaarikkoSource :
- Journal of reconstructive microsurgery [ 1098-8947 ] ; 2016.
English descriptors
- KwdEn :
- Animals, Forkhead Transcription Factors (pharmacology), Humans, Inflammation (pathology), Intercellular Signaling Peptides and Proteins (pharmacology), Lymph Nodes (transplantation), Lymphangiogenesis (physiology), Lymphatic Metastasis (pathology), Lymphatic System (embryology), Lymphedema (drug therapy), Lymphedema (surgery), Microsurgery, Vascular Endothelial Growth Factors (pharmacology).
- MESH :
- chemical , pharmacology : Forkhead Transcription Factors, Intercellular Signaling Peptides and Proteins, Vascular Endothelial Growth Factors.
- drug therapy : Lymphedema.
- embryology : Lymphatic System.
- pathology : Inflammation, Lymphatic Metastasis.
- physiology : Lymphangiogenesis.
- surgery : Lymphedema.
- transplantation : Lymph Nodes.
- Animals, Humans, Microsurgery.
Abstract
Lymphedema is a progressive disease caused by damage to the lymphatic network. Recent development in the fields of preclinical growth factor research and lymphedema microsurgery promise new hope for lymphedema patients. In this article, we review the latest results on basic research and highlight the role of specific growth factors in normal lymphatic development and several disease states. Lymph node transfer, a new promising method in reconstructive lymphatic microsurgery, is also dependent on the lymphatic vascular regrowth and lymphangiogenic growth factors. We discuss the scientific basis of lymph node transfer and therapeutic potential of lymphangiogenic growth factors in the treatment of lymphedema.
DOI: 10.1055/s-0035-1544179
PubMed: 25665098
Links to Exploration step
pubmed:25665098Le document en format XML
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<author><name sortKey="Hartiala, Pauliina" sort="Hartiala, Pauliina" uniqKey="Hartiala P" first="Pauliina" last="Hartiala">Pauliina Hartiala</name>
<affiliation><nlm:affiliation>Department of Plastic and General Surgery, Turku University Central Hospital, Turku, Finland.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Saarikko, Anne M" sort="Saarikko, Anne M" uniqKey="Saarikko A" first="Anne M" last="Saarikko">Anne M. Saarikko</name>
<affiliation><nlm:affiliation>Department of Plastic and General Surgery, Turku University Central Hospital, Turku, Finland.</nlm:affiliation>
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<affiliation><nlm:affiliation>Department of Plastic and General Surgery, Turku University Central Hospital, Turku, Finland.</nlm:affiliation>
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<author><name sortKey="Saarikko, Anne M" sort="Saarikko, Anne M" uniqKey="Saarikko A" first="Anne M" last="Saarikko">Anne M. Saarikko</name>
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<series><title level="j">Journal of reconstructive microsurgery</title>
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<term>Intercellular Signaling Peptides and Proteins (pharmacology)</term>
<term>Lymph Nodes (transplantation)</term>
<term>Lymphangiogenesis (physiology)</term>
<term>Lymphatic Metastasis (pathology)</term>
<term>Lymphatic System (embryology)</term>
<term>Lymphedema (drug therapy)</term>
<term>Lymphedema (surgery)</term>
<term>Microsurgery</term>
<term>Vascular Endothelial Growth Factors (pharmacology)</term>
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<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Forkhead Transcription Factors</term>
<term>Intercellular Signaling Peptides and Proteins</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Lymphedema</term>
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<keywords scheme="MESH" qualifier="embryology" xml:lang="en"><term>Lymphatic System</term>
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<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Inflammation</term>
<term>Lymphatic Metastasis</term>
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<front><div type="abstract" xml:lang="en">Lymphedema is a progressive disease caused by damage to the lymphatic network. Recent development in the fields of preclinical growth factor research and lymphedema microsurgery promise new hope for lymphedema patients. In this article, we review the latest results on basic research and highlight the role of specific growth factors in normal lymphatic development and several disease states. Lymph node transfer, a new promising method in reconstructive lymphatic microsurgery, is also dependent on the lymphatic vascular regrowth and lymphangiogenic growth factors. We discuss the scientific basis of lymph node transfer and therapeutic potential of lymphangiogenic growth factors in the treatment of lymphedema.</div>
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<Title>Journal of reconstructive microsurgery</Title>
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<Abstract><AbstractText>Lymphedema is a progressive disease caused by damage to the lymphatic network. Recent development in the fields of preclinical growth factor research and lymphedema microsurgery promise new hope for lymphedema patients. In this article, we review the latest results on basic research and highlight the role of specific growth factors in normal lymphatic development and several disease states. Lymph node transfer, a new promising method in reconstructive lymphatic microsurgery, is also dependent on the lymphatic vascular regrowth and lymphangiogenic growth factors. We discuss the scientific basis of lymph node transfer and therapeutic potential of lymphangiogenic growth factors in the treatment of lymphedema.</AbstractText>
<CopyrightInformation>Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.</CopyrightInformation>
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