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Bilayered negative-pressure wound therapy preventing leg incision morbidity in coronary artery bypass graft patients: A randomized controlled trial.

Identifieur interne : 000412 ( PubMed/Corpus ); précédent : 000411; suivant : 000413

Bilayered negative-pressure wound therapy preventing leg incision morbidity in coronary artery bypass graft patients: A randomized controlled trial.

Auteurs : Yongchao Yu ; Zhigang Song ; Zhiyun Xu ; Xiaofei Ye ; Chunyu Xue ; Junhui Li ; Hongda Bi

Source :

RBID : pubmed:28099357

English descriptors

Abstract

The harvesting of great saphenous veins for coronary artery bypass graft (CABG) patients may result in significant complications, including lymphorrhagia, lymphoedema, incision infection, wound dehiscence, and skin flap necrosis. We investigated the function of a self-designed bilayered negative pressure wound therapy (b-NPWT) for reducing the above-mentioned complications using a clinical randomized controlled trial.

DOI: 10.1097/MD.0000000000005925
PubMed: 28099357

Links to Exploration step

pubmed:28099357

Le document en format XML

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<name sortKey="Yu, Yongchao" sort="Yu, Yongchao" uniqKey="Yu Y" first="Yongchao" last="Yu">Yongchao Yu</name>
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<nlm:affiliation>aDepartment of Cardiac Surgery bDepartment of Statistics, Faculty of Medical Services cDepartment of Plastic Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, China.</nlm:affiliation>
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<name sortKey="Song, Zhigang" sort="Song, Zhigang" uniqKey="Song Z" first="Zhigang" last="Song">Zhigang Song</name>
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<name sortKey="Xue, Chunyu" sort="Xue, Chunyu" uniqKey="Xue C" first="Chunyu" last="Xue">Chunyu Xue</name>
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<name sortKey="Li, Junhui" sort="Li, Junhui" uniqKey="Li J" first="Junhui" last="Li">Junhui Li</name>
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<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Negative-Pressure Wound Therapy (methods)</term>
<term>Pilot Projects</term>
<term>Postoperative Complications (prevention & control)</term>
<term>Saphenous Vein (transplantation)</term>
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<term>Negative-Pressure Wound Therapy</term>
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<term>Postoperative Complications</term>
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<term>Saphenous Vein</term>
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<term>Aged</term>
<term>Coronary Artery Bypass</term>
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<div type="abstract" xml:lang="en">The harvesting of great saphenous veins for coronary artery bypass graft (CABG) patients may result in significant complications, including lymphorrhagia, lymphoedema, incision infection, wound dehiscence, and skin flap necrosis. We investigated the function of a self-designed bilayered negative pressure wound therapy (b-NPWT) for reducing the above-mentioned complications using a clinical randomized controlled trial.</div>
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<Day>10</Day>
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<Volume>96</Volume>
<Issue>3</Issue>
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<Year>2017</Year>
<Month>Jan</Month>
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<Title>Medicine</Title>
<ISOAbbreviation>Medicine (Baltimore)</ISOAbbreviation>
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<ArticleTitle>Bilayered negative-pressure wound therapy preventing leg incision morbidity in coronary artery bypass graft patients: A randomized controlled trial.</ArticleTitle>
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<AbstractText Label="BACKGROUNDS" NlmCategory="BACKGROUND">The harvesting of great saphenous veins for coronary artery bypass graft (CABG) patients may result in significant complications, including lymphorrhagia, lymphoedema, incision infection, wound dehiscence, and skin flap necrosis. We investigated the function of a self-designed bilayered negative pressure wound therapy (b-NPWT) for reducing the above-mentioned complications using a clinical randomized controlled trial.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">A single-center, pilot randomized controlled trial was conducted. From December 2013 to March 2014, a total of 72 coronary heart disease patients (48 men and 24 women) received CABG therapy, with great saphenous veins were selected as grafts. Patients were equally randomized into a treatment and a control group. After the harvesting of the great saphenous veins and direct closure of the wound with sutures, b-NPWT was used for the thigh incision in the treatment group for 5 days (treatment thigh). Traditional surgical pads were applied to both the shank incisions of the treatment group patients (treatment shank) and the entire incisions of the control group (control thigh, control shank). Postoperative complications were recorded and statistically analyzed based on outcomes of thigh treatment, shank treatment, thigh control, and shank control groups.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The incidence rates of early complications, such as lymphorrhagia, lymphoedema, infection, wound dehiscence, and skin flap necrosis, of the vascular donor site in the thigh treatment group was significantly lower than those in the 3 other groups.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">The self-designed b-NPWT can effectively reduce postoperative complications, such as lymphedema, incision infection, wound dehiscence, and skin flap necrosis, in CABG patients who underwent great saphenous veins harvesting.</AbstractText>
<AbstractText Label="TRIAL REGISTRATION" NlmCategory="BACKGROUND">ClinicalTrials.gov. The unique registration number is NCT02010996.</AbstractText>
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