Coexistent yellow nail syndrome and selective antibody deficiency.
Identifieur interne : 003E14 ( PubMed/Checkpoint ); précédent : 003E13; suivant : 003E15Coexistent yellow nail syndrome and selective antibody deficiency.
Auteurs : Aleksandra Bokszczanin [États-Unis] ; Arnold I. LevinsonSource :
- Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology [ 1081-1206 ] ; 2003.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Anticorps antibactériens (immunologie), Anticorps antibactériens (sang), Déficit en IgG (immunologie), Déficit en IgG (étiologie), Déficits immunitaires (immunologie), Déficits immunitaires (étiologie), Femelle, Haemophilus influenzae (immunologie), Humains, Immunoglobuline A (immunologie), Immunoglobuline A (sang), Immunoglobuline G (immunologie), Immunoglobuline G (sang), Immunoglobuline M (immunologie), Immunoglobuline M (sang), Infections de l'appareil respiratoire (immunologie), Infections de l'appareil respiratoire (étiologie), Infections à Haemophilus (immunologie), Infections à Haemophilus (microbiologie), Infections à pneumocoques (immunologie), Infections à pneumocoques (microbiologie), Onychopathies (immunologie), Onychopathies (étiologie), Polyosides bactériens (effets indésirables), Polyosides bactériens (immunologie), Production d'anticorps (immunologie).
- MESH :
- effets indésirables : Polyosides bactériens.
- immunologie : Anticorps antibactériens, Déficit en IgG, Déficits immunitaires, Haemophilus influenzae, Immunoglobuline A, Immunoglobuline G, Immunoglobuline M, Infections de l'appareil respiratoire, Infections à Haemophilus, Infections à pneumocoques, Onychopathies, Polyosides bactériens, Production d'anticorps.
- microbiologie : Infections à Haemophilus, Infections à pneumocoques.
- sang : Anticorps antibactériens, Immunoglobuline A, Immunoglobuline G, Immunoglobuline M.
- étiologie : Déficit en IgG, Déficits immunitaires, Infections de l'appareil respiratoire, Onychopathies.
- Adulte d'âge moyen, Femelle, Humains.
English descriptors
- KwdEn :
- Antibodies, Bacterial (blood), Antibodies, Bacterial (immunology), Antibody Formation (immunology), Female, Haemophilus Infections (immunology), Haemophilus Infections (microbiology), Haemophilus influenzae (immunology), Humans, IgG Deficiency (etiology), IgG Deficiency (immunology), Immunoglobulin A (blood), Immunoglobulin A (immunology), Immunoglobulin G (blood), Immunoglobulin G (immunology), Immunoglobulin M (blood), Immunoglobulin M (immunology), Immunologic Deficiency Syndromes (etiology), Immunologic Deficiency Syndromes (immunology), Middle Aged, Nail Diseases (etiology), Nail Diseases (immunology), Pneumococcal Infections (immunology), Pneumococcal Infections (microbiology), Polysaccharides, Bacterial (adverse effects), Polysaccharides, Bacterial (immunology), Respiratory Tract Infections (etiology), Respiratory Tract Infections (immunology).
- MESH :
- chemical , adverse effects : Polysaccharides, Bacterial.
- chemical , blood : Antibodies, Bacterial, Immunoglobulin A, Immunoglobulin G, Immunoglobulin M.
- chemical , immunology : Antibodies, Bacterial, Immunoglobulin A, Immunoglobulin G, Immunoglobulin M, Polysaccharides, Bacterial.
- etiology : IgG Deficiency, Immunologic Deficiency Syndromes, Nail Diseases, Respiratory Tract Infections.
- immunology : Antibody Formation, Haemophilus Infections, Haemophilus influenzae, IgG Deficiency, Immunologic Deficiency Syndromes, Nail Diseases, Pneumococcal Infections, Respiratory Tract Infections.
- microbiology : Haemophilus Infections, Pneumococcal Infections.
- Female, Humans, Middle Aged.
Abstract
Yellow nail syndrome (YNS) is a rare, often underdiagnosed condition of unknown origin. The clinical features of the syndrome include yellow nails, chronic sinusitis, bronchiectasis, pleural effusion, and lymphoedema. Despite the frequent occurrence of upper and lower respiratory tract infections in patients with YNS, comprehensive analysis of their humoral immunity has not been previously reported.
DOI: 10.1016/S1081-1206(10)61521-9
PubMed: 14692436
Affiliations:
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(blood)</term><term>Immunoglobulin M (immunology)</term><term>Immunologic Deficiency Syndromes (etiology)</term><term>Immunologic Deficiency Syndromes (immunology)</term><term>Middle Aged</term><term>Nail Diseases (etiology)</term><term>Nail Diseases (immunology)</term><term>Pneumococcal Infections (immunology)</term><term>Pneumococcal Infections (microbiology)</term><term>Polysaccharides, Bacterial (adverse effects)</term><term>Polysaccharides, Bacterial (immunology)</term><term>Respiratory Tract Infections (etiology)</term><term>Respiratory Tract Infections (immunology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Anticorps antibactériens (immunologie)</term><term>Anticorps antibactériens (sang)</term><term>Déficit en IgG (immunologie)</term><term>Déficit en IgG (étiologie)</term><term>Déficits immunitaires (immunologie)</term><term>Déficits immunitaires (étiologie)</term><term>Femelle</term><term>Haemophilus influenzae (immunologie)</term><term>Humains</term><term>Immunoglobuline A (immunologie)</term><term>Immunoglobuline A (sang)</term><term>Immunoglobuline G (immunologie)</term><term>Immunoglobuline G (sang)</term><term>Immunoglobuline M (immunologie)</term><term>Immunoglobuline M (sang)</term><term>Infections de l'appareil respiratoire (immunologie)</term><term>Infections de l'appareil respiratoire (étiologie)</term><term>Infections à Haemophilus (immunologie)</term><term>Infections à Haemophilus (microbiologie)</term><term>Infections à pneumocoques (immunologie)</term><term>Infections à pneumocoques (microbiologie)</term><term>Onychopathies (immunologie)</term><term>Onychopathies (étiologie)</term><term>Polyosides bactériens (effets indésirables)</term><term>Polyosides bactériens (immunologie)</term><term>Production d'anticorps (immunologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Polysaccharides, Bacterial</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antibodies, Bacterial</term><term>Immunoglobulin A</term><term>Immunoglobulin G</term><term>Immunoglobulin M</term></keywords><keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Antibodies, Bacterial</term><term>Immunoglobulin A</term><term>Immunoglobulin G</term><term>Immunoglobulin M</term><term>Polysaccharides, Bacterial</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Polyosides bactériens</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>IgG Deficiency</term><term>Immunologic Deficiency Syndromes</term><term>Nail Diseases</term><term>Respiratory Tract Infections</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Anticorps antibactériens</term><term>Déficit en IgG</term><term>Déficits immunitaires</term><term>Haemophilus influenzae</term><term>Immunoglobuline A</term><term>Immunoglobuline G</term><term>Immunoglobuline M</term><term>Infections de l'appareil respiratoire</term><term>Infections à Haemophilus</term><term>Infections à pneumocoques</term><term>Onychopathies</term><term>Polyosides bactériens</term><term>Production d'anticorps</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Antibody Formation</term><term>Haemophilus Infections</term><term>Haemophilus influenzae</term><term>IgG Deficiency</term><term>Immunologic Deficiency Syndromes</term><term>Nail Diseases</term><term>Pneumococcal Infections</term><term>Respiratory Tract Infections</term></keywords><keywords scheme="MESH" qualifier="microbiologie" xml:lang="fr"><term>Infections à Haemophilus</term><term>Infections à pneumocoques</term></keywords><keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Haemophilus Infections</term><term>Pneumococcal Infections</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Anticorps antibactériens</term><term>Immunoglobuline A</term><term>Immunoglobuline G</term><term>Immunoglobuline M</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Déficit en IgG</term><term>Déficits immunitaires</term><term>Infections de l'appareil respiratoire</term><term>Onychopathies</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Female</term><term>Humans</term><term>Middle Aged</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Femelle</term><term>Humains</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Yellow nail syndrome (YNS) is a rare, often underdiagnosed condition of unknown origin. The clinical features of the syndrome include yellow nails, chronic sinusitis, bronchiectasis, pleural effusion, and lymphoedema. Despite the frequent occurrence of upper and lower respiratory tract infections in patients with YNS, comprehensive analysis of their humoral immunity has not been previously reported.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">14692436</PMID><DateCreated><Year>2003</Year><Month>12</Month><Day>24</Day></DateCreated><DateCompleted><Year>2004</Year><Month>02</Month><Day>20</Day></DateCompleted><DateRevised><Year>2004</Year><Month>11</Month><Day>17</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">1081-1206</ISSN><JournalIssue CitedMedium="Print"><Volume>91</Volume><Issue>5</Issue><PubDate><Year>2003</Year><Month>Nov</Month></PubDate></JournalIssue><Title>Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology</Title><ISOAbbreviation>Ann. Allergy Asthma Immunol.</ISOAbbreviation></Journal><ArticleTitle>Coexistent yellow nail syndrome and selective antibody deficiency.</ArticleTitle><Pagination><MedlinePgn>496-500</MedlinePgn></Pagination><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Yellow nail syndrome (YNS) is a rare, often underdiagnosed condition of unknown origin. The clinical features of the syndrome include yellow nails, chronic sinusitis, bronchiectasis, pleural effusion, and lymphoedema. Despite the frequent occurrence of upper and lower respiratory tract infections in patients with YNS, comprehensive analysis of their humoral immunity has not been previously reported.</AbstractText><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To present the case of a patient with YNS whose recurrent upper and lower respiratory tract infections may have been caused by an underlying selective antibody deficiency that manifests as impaired IgG antibody response to polysaccharide antigens.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">The patient underwent cultures of purulent sputum for Streptococcus pneumoniae and Haemophilus influenzae, bronchial washings for H. influenzae, and nail scrapings for fungi. Her serum levels of IgG, IgA, IgM, IgG subclasses, and serum titers of IgG antitetanus toxoid, anti-H. influenzae, and anti-S. pneumoniae antibodies were measured.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Cultures of purulent sputum were positive on multiple occasions for S. pneumoniae and H. influenzae and bronchial washings were positive for H. influenzae. Nail scrapings were consistently negative for fungi. She had no reductions in serum levels of IgG, IgA, IgM, or IgG subclasses and had normal serum titers of IgG antitetanus toxoid antibodies. However, she demonstrated impaired IgG antibody responses following immunization with Pneumovax and an H. influenza B vaccine.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">This case report describes the first comprehensive analysis of humoral immune function in a patient with YNS. The finding of a selective antibody deficiency in our patient provides a potential explanation for the occurrence of respiratory infections in YNS. Accordingly, we recommend that functional antibody determinations and quantitative serum immunoglobulins be evaluated in patients diagnosed as having this unusual, enigmatic syndrome.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Bokszczanin</LastName><ForeName>Aleksandra</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania, School of Medicine, Philadelphia, Pennsylvania 19104-6160, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Levinson</LastName><ForeName>Arnold I</ForeName><Initials>AI</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Ann Allergy Asthma Immunol</MedlineTA><NlmUniqueID>9503580</NlmUniqueID><ISSNLinking>1081-1206</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000907">Antibodies, Bacterial</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007070">Immunoglobulin A</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007074">Immunoglobulin G</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007075">Immunoglobulin M</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D011135">Polysaccharides, Bacterial</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000907" MajorTopicYN="N">Antibodies, Bacterial</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000917" MajorTopicYN="N">Antibody Formation</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006192" MajorTopicYN="N">Haemophilus Infections</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006193" MajorTopicYN="N">Haemophilus influenzae</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017099" MajorTopicYN="N">IgG Deficiency</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007070" MajorTopicYN="N">Immunoglobulin A</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007074" MajorTopicYN="N">Immunoglobulin G</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007075" MajorTopicYN="N">Immunoglobulin M</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007153" MajorTopicYN="N">Immunologic Deficiency Syndromes</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009260" MajorTopicYN="N">Nail Diseases</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011008" MajorTopicYN="N">Pneumococcal Infections</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011135" MajorTopicYN="N">Polysaccharides, Bacterial</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012141" MajorTopicYN="N">Respiratory Tract Infections</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2003</Year><Month>12</Month><Day>25</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2004</Year><Month>2</Month><Day>21</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2003</Year><Month>12</Month><Day>25</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">14692436</ArticleId><ArticleId IdType="pii">S1081-1206(10)61521-9</ArticleId><ArticleId IdType="doi">10.1016/S1081-1206(10)61521-9</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>États-Unis</li></country></list><tree><noCountry><name sortKey="Levinson, Arnold I" sort="Levinson, Arnold I" uniqKey="Levinson A" first="Arnold I" last="Levinson">Arnold I. Levinson</name></noCountry><country name="États-Unis"><noRegion><name sortKey="Bokszczanin, Aleksandra" sort="Bokszczanin, Aleksandra" uniqKey="Bokszczanin A" first="Aleksandra" last="Bokszczanin">Aleksandra Bokszczanin</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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