Risk Factors for Podoconiosis: Kamwenge District, Western Uganda, September 2015.
Identifieur interne : 000131 ( PubMed/Checkpoint ); précédent : 000130; suivant : 000132Risk Factors for Podoconiosis: Kamwenge District, Western Uganda, September 2015.
Auteurs : Christine Kihembo [Ouganda] ; Ben Masiira [Ouganda] ; William Z. Lali [Ouganda] ; Gabriel K. Matwale [Ouganda] ; Joseph K B. Matovu [Ouganda] ; Frank Kaharuza [Ouganda] ; Alex R. Ario [Ouganda] ; Immaculate Nabukenya [Ouganda] ; Issa Makumbi [Ouganda] ; Monica Musenero [Ouganda] ; Bao-Ping Zhu [Ouganda] ; Miriam Nanyunja [Ouganda]Source :
- The American journal of tropical medicine and hygiene [ 1476-1645 ] ; 2017.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Chaussures, Comportement en matière de santé, Facteurs de risque, Femelle, Filariose lymphatique (diagnostic), Filariose lymphatique (épidémiologie), Humains, Hygiène, Jeune adulte, Maladies négligées (diagnostic), Maladies négligées (épidémiologie), Mâle, Ouganda (épidémiologie), Prévalence, Sol (parasitologie), Sujet âgé, Sujet âgé de 80 ans ou plus, Taille d'échantillon, Éléphantiasis (diagnostic), Éléphantiasis (épidémiologie), Études cas-témoins.
- MESH :
- diagnostic : Filariose lymphatique, Maladies négligées, Éléphantiasis.
- parasitologie : Sol.
- épidémiologie : Filariose lymphatique, Maladies négligées, Ouganda, Éléphantiasis.
- Adolescent, Adulte, Adulte d'âge moyen, Chaussures, Comportement en matière de santé, Facteurs de risque, Femelle, Humains, Hygiène, Jeune adulte, Mâle, Prévalence, Sujet âgé, Sujet âgé de 80 ans ou plus, Taille d'échantillon, Études cas-témoins.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Aged, 80 and over, Case-Control Studies, Elephantiasis (diagnosis), Elephantiasis (epidemiology), Elephantiasis, Filarial (diagnosis), Elephantiasis, Filarial (epidemiology), Female, Health Behavior, Humans, Hygiene, Male, Middle Aged, Neglected Diseases (diagnosis), Neglected Diseases (epidemiology), Prevalence, Risk Factors, Sample Size, Shoes, Soil (parasitology), Uganda (epidemiology), Young Adult.
- MESH :
- chemical , parasitology : Soil.
- diagnosis : Elephantiasis, Elephantiasis, Filarial, Neglected Diseases.
- epidemiology : Elephantiasis, Elephantiasis, Filarial, Neglected Diseases, Uganda.
- Adolescent, Adult, Aged, Aged, 80 and over, Case-Control Studies, Female, Health Behavior, Humans, Hygiene, Male, Middle Aged, Prevalence, Risk Factors, Sample Size, Shoes, Young Adult.
Abstract
AbstractPodoconiosis, a noninfectious elephantiasis, is a disabling neglected tropical disease. In August 2015, an elephantiasis case-cluster was reported in Kamwenge District, western Uganda. We investigated to identify the disease's nature and risk factors. We defined a suspected podoconiosis case as onset in a Kamwenge resident of bilateral asymmetrical lower limb swelling lasting ≥ 1 month, plus ≥ 1 of the following associated symptoms: skin itching, burning sensation, plantar edema, lymph ooze, prominent skin markings, rigid toes, or mossy papillomata. A probable case was a suspected case with negative microfilaria antigen immunochromatographic card test (ruling out filarial elephantiasis). We conducted active case-finding. In a case-control investigation, we tested the hypothesis that the disease was caused by prolonged foot skin exposure to irritant soils, using 40 probable case-persons and 80 asymptomatic village control-persons, individually matched by age and sex. We collected soil samples to characterize irritants. We identified 52 suspected (including 40 probable) cases with onset from 1980 to 2015. Prevalence rates increased with age; annual incidence (by reported onset of disease) was stable over time at 2.9/100,000. We found that 93% (37/40) of cases and 68% (54/80) of controls never wore shoes at work (Mantel-Haenszel odds ratio [ORMH] = 7.7; 95% [confidence interval] CI = 2.0-30); 80% (32/40) of cases and 49% (39/80) of controls never wore shoes at home (ORMH = 5.2; 95% CI = 1.8-15); and 70% (27/39) of cases and 44% (35/79) of controls washed feet at day end (versus immediately after work) (OR = 11; 95% CI = 2.1-56). Soil samples were characterized as rich black-red volcanic clays. In conclusion, this reported elephantiasis is podoconiosis associated with prolonged foot exposure to volcanic soil. We recommended foot hygiene and universal use of protective shoes.
DOI: 10.4269/ajtmh.16-0932
PubMed: 28719274
Affiliations:
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<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Case-Control Studies</term>
<term>Elephantiasis (diagnosis)</term>
<term>Elephantiasis (epidemiology)</term>
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<term>Facteurs de risque</term>
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<term>Filariose lymphatique (épidémiologie)</term>
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<term>Éléphantiasis</term>
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<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Case-Control Studies</term>
<term>Female</term>
<term>Health Behavior</term>
<term>Humans</term>
<term>Hygiene</term>
<term>Male</term>
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<term>Prevalence</term>
<term>Risk Factors</term>
<term>Sample Size</term>
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<term>Adulte d'âge moyen</term>
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<term>Comportement en matière de santé</term>
<term>Facteurs de risque</term>
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<term>Prévalence</term>
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<front><div type="abstract" xml:lang="en">AbstractPodoconiosis, a noninfectious elephantiasis, is a disabling neglected tropical disease. In August 2015, an elephantiasis case-cluster was reported in Kamwenge District, western Uganda. We investigated to identify the disease's nature and risk factors. We defined a suspected podoconiosis case as onset in a Kamwenge resident of bilateral asymmetrical lower limb swelling lasting ≥ 1 month, plus ≥ 1 of the following associated symptoms: skin itching, burning sensation, plantar edema, lymph ooze, prominent skin markings, rigid toes, or mossy papillomata. A probable case was a suspected case with negative microfilaria antigen immunochromatographic card test (ruling out filarial elephantiasis). We conducted active case-finding. In a case-control investigation, we tested the hypothesis that the disease was caused by prolonged foot skin exposure to irritant soils, using 40 probable case-persons and 80 asymptomatic village control-persons, individually matched by age and sex. We collected soil samples to characterize irritants. We identified 52 suspected (including 40 probable) cases with onset from 1980 to 2015. Prevalence rates increased with age; annual incidence (by reported onset of disease) was stable over time at 2.9/100,000. We found that 93% (37/40) of cases and 68% (54/80) of controls never wore shoes at work (Mantel-Haenszel odds ratio [ORMH] = 7.7; 95% [confidence interval] CI = 2.0-30); 80% (32/40) of cases and 49% (39/80) of controls never wore shoes at home (ORMH = 5.2; 95% CI = 1.8-15); and 70% (27/39) of cases and 44% (35/79) of controls washed feet at day end (versus immediately after work) (OR = 11; 95% CI = 2.1-56). Soil samples were characterized as rich black-red volcanic clays. In conclusion, this reported elephantiasis is podoconiosis associated with prolonged foot exposure to volcanic soil. We recommended foot hygiene and universal use of protective shoes.</div>
</front>
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</Journal>
<ArticleTitle>Risk Factors for Podoconiosis: Kamwenge District, Western Uganda, September 2015.</ArticleTitle>
<Pagination><MedlinePgn>1490-1496</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.4269/ajtmh.16-0932</ELocationID>
<Abstract><AbstractText>AbstractPodoconiosis, a noninfectious elephantiasis, is a disabling neglected tropical disease. In August 2015, an elephantiasis case-cluster was reported in Kamwenge District, western Uganda. We investigated to identify the disease's nature and risk factors. We defined a suspected podoconiosis case as onset in a Kamwenge resident of bilateral asymmetrical lower limb swelling lasting ≥ 1 month, plus ≥ 1 of the following associated symptoms: skin itching, burning sensation, plantar edema, lymph ooze, prominent skin markings, rigid toes, or mossy papillomata. A probable case was a suspected case with negative microfilaria antigen immunochromatographic card test (ruling out filarial elephantiasis). We conducted active case-finding. In a case-control investigation, we tested the hypothesis that the disease was caused by prolonged foot skin exposure to irritant soils, using 40 probable case-persons and 80 asymptomatic village control-persons, individually matched by age and sex. We collected soil samples to characterize irritants. We identified 52 suspected (including 40 probable) cases with onset from 1980 to 2015. Prevalence rates increased with age; annual incidence (by reported onset of disease) was stable over time at 2.9/100,000. We found that 93% (37/40) of cases and 68% (54/80) of controls never wore shoes at work (Mantel-Haenszel odds ratio [ORMH] = 7.7; 95% [confidence interval] CI = 2.0-30); 80% (32/40) of cases and 49% (39/80) of controls never wore shoes at home (ORMH = 5.2; 95% CI = 1.8-15); and 70% (27/39) of cases and 44% (35/79) of controls washed feet at day end (versus immediately after work) (OR = 11; 95% CI = 2.1-56). Soil samples were characterized as rich black-red volcanic clays. In conclusion, this reported elephantiasis is podoconiosis associated with prolonged foot exposure to volcanic soil. We recommended foot hygiene and universal use of protective shoes.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Kihembo</LastName>
<ForeName>Christine</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Epidemiology and Surveillance Division, Ministry of Health, Kampala, Uganda.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Uganda Public Health Fellowship Program, Field Epidemiology Track, Kampala, Uganda.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Masiira</LastName>
<ForeName>Ben</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Epidemiology and Surveillance Division, Ministry of Health, Kampala, Uganda.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Uganda Public Health Fellowship Program, Field Epidemiology Track, Kampala, Uganda.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lali</LastName>
<ForeName>William Z</ForeName>
<Initials>WZ</Initials>
<AffiliationInfo><Affiliation>World Health Organization Uganda Country Office, Kampala, Uganda.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Matwale</LastName>
<ForeName>Gabriel K</ForeName>
<Initials>GK</Initials>
<AffiliationInfo><Affiliation>Vector Control Division, Ministry of Health, Kampala, Uganda.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Matovu</LastName>
<ForeName>Joseph K B</ForeName>
<Initials>JKB</Initials>
<AffiliationInfo><Affiliation>Makerere University School of Public Health, Kampala, Uganda.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kaharuza</LastName>
<ForeName>Frank</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Makerere University School of Public Health, Kampala, Uganda.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ario</LastName>
<ForeName>Alex R</ForeName>
<Initials>AR</Initials>
<AffiliationInfo><Affiliation>Uganda Public Health Fellowship Program, Field Epidemiology Track, Kampala, Uganda.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Nabukenya</LastName>
<ForeName>Immaculate</ForeName>
<Initials>I</Initials>
<AffiliationInfo><Affiliation>Epidemiology and Surveillance Division, Ministry of Health, Kampala, Uganda.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Makumbi</LastName>
<ForeName>Issa</ForeName>
<Initials>I</Initials>
<AffiliationInfo><Affiliation>Public Health Emergency Operations Centre, Ministry of Health, Kampala, Uganda.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Musenero</LastName>
<ForeName>Monica</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Epidemiology and Surveillance Division, Ministry of Health, Kampala, Uganda.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zhu</LastName>
<ForeName>Bao-Ping</ForeName>
<Initials>BP</Initials>
<AffiliationInfo><Affiliation>U.S. Centers for Disease Control and Prevention, Kampala, Uganda.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Nanyunja</LastName>
<ForeName>Miriam</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>World Health Organization Uganda Country Office, Kampala, Uganda.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Am J Trop Med Hyg</MedlineTA>
<NlmUniqueID>0370507</NlmUniqueID>
<ISSNLinking>0002-9637</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D012987">Soil</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>AIM</CitationSubset>
<CitationSubset>IM</CitationSubset>
<CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Rev Soc Bras Med Trop. 2014 May-Jun;47(3):359-66</RefSource>
<PMID Version="1">25075488</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trop Med Int Health. 2006 Jul;11(7):1136-44</RefSource>
<PMID Version="1">16827714</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trans R Soc Trop Med Hyg. 2007 Dec;101(12):1175-80</RefSource>
<PMID Version="1">17976670</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Int Health. 2011 Sep;3(3):176-81</RefSource>
<PMID Version="1">24038367</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Acta Trop. 2001 Feb 23;78(2):171-6</RefSource>
<PMID Version="1">11230827</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Bull World Health Organ. 2015 Oct 1;93(10):712-718</RefSource>
<PMID Version="1">26600613</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>PLoS One. 2013 Jul 09;8(7):e68330</RefSource>
<PMID Version="1">23874587</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>PLoS Negl Trop Dis. 2013 Dec 05;7(12):e2554</RefSource>
<PMID Version="1">24340109</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Ann Trop Med Parasitol. 2008 Sep;102(6):529-40</RefSource>
<PMID Version="1">18782492</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Trop Med Hyg. 2015 Jan;92(1):148-58</RefSource>
<PMID Version="1">25404069</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Parasit Vectors. 2014 Aug 27;7:397</RefSource>
<PMID Version="1">25164687</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Sci Total Environ. 2002 May 27;291(1-3):1-32</RefSource>
<PMID Version="1">12150429</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Lymphology. 2010 Dec;43(4):168-77</RefSource>
<PMID Version="1">21446572</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trans R Soc Trop Med Hyg. 2007 Jun;101(6):621-3</RefSource>
<PMID Version="1">17316723</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trans R Soc Trop Med Hyg. 2007 Jan;101(1):91-6</RefSource>
<PMID Version="1">16884751</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trans R Soc Trop Med Hyg. 2008 May;102(5):439-44</RefSource>
<PMID Version="1">18339411</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trans R Soc Trop Med Hyg. 2014 Dec;108(12):751-8</RefSource>
<PMID Version="1">25282001</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Ann Trop Med Parasitol. 2009 Jul;103(5):377-82</RefSource>
<PMID Version="1">19583908</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Vector Borne Dis. 2015 Jun;52(2):111-5</RefSource>
<PMID Version="1">26119541</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>PLoS Negl Trop Dis. 2012;6(7):e1744</RefSource>
<PMID Version="1">22816005</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trans R Soc Trop Med Hyg. 2010 Jan;104(1):42-7</RefSource>
<PMID Version="1">19717176</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Southeast Asian J Trop Med Public Health. 1999 Mar;30(1):47-51</RefSource>
<PMID Version="1">10695788</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Lancet. 2012 Mar 17;379(9820):1004</RefSource>
<PMID Version="1">22423883</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trop Geogr Med. 1974 Sep;26(3):225-30</RefSource>
<PMID Version="1">4439458</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Parasitol Today. 1997 Oct;13(10):401-4</RefSource>
<PMID Version="1">15275155</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trop Med Int Health. 2012 Jun;17(6):722-6</RefSource>
<PMID Version="1">22487446</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>N Engl J Med. 2012 Mar 29;366(13):1200-8</RefSource>
<PMID Version="1">22455414</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trans R Soc Trop Med Hyg. 1976;70(4):288-95</RefSource>
<PMID Version="1">1006757</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Parasitol Res. 2012 Sep;111(3):1379-83</RefSource>
<PMID Version="1">22392137</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trans R Soc Trop Med Hyg. 2014 Sep;108(9):528-9</RefSource>
<PMID Version="1">25059525</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>PLoS Negl Trop Dis. 2011 Jun;5(6):e1184</RefSource>
<PMID Version="1">21666795</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Trop Med Hyg. 2008 Jan;78(1):28-34</RefSource>
<PMID Version="1">18187781</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Neth J Med. 2012 Jun;70(5):210-4</RefSource>
<PMID Version="1">22744921</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trop Doct. 1992 Jul;22(3):109-12</RefSource>
<PMID Version="1">1641880</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Int Health. 2015 Sep;7(5):306-16</RefSource>
<PMID Version="1">26185194</PMID>
</CommentsCorrections>
</CommentsCorrectionsList>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016022" MajorTopicYN="N">Case-Control Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004604" MajorTopicYN="N">Elephantiasis</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004605" MajorTopicYN="N">Elephantiasis, Filarial</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015438" MajorTopicYN="N">Health Behavior</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006920" MajorTopicYN="N">Hygiene</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D058069" MajorTopicYN="N">Neglected Diseases</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015995" MajorTopicYN="N">Prevalence</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012307" MajorTopicYN="N">Risk Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018401" MajorTopicYN="N">Sample Size</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012775" MajorTopicYN="N">Shoes</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012987" MajorTopicYN="N">Soil</DescriptorName>
<QualifierName UI="Q000469" MajorTopicYN="N">parasitology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014454" MajorTopicYN="N">Uganda</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="pmc-release"><Year>2018</Year>
<Month>06</Month>
<Day>07</Day>
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<Hour>6</Hour>
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<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">28719274</ArticleId>
<ArticleId IdType="doi">10.4269/ajtmh.16-0932</ArticleId>
<ArticleId IdType="pmc">PMC5462591</ArticleId>
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<affiliations><list><country><li>Ouganda</li>
</country>
</list>
<tree><country name="Ouganda"><noRegion><name sortKey="Kihembo, Christine" sort="Kihembo, Christine" uniqKey="Kihembo C" first="Christine" last="Kihembo">Christine Kihembo</name>
</noRegion>
<name sortKey="Ario, Alex R" sort="Ario, Alex R" uniqKey="Ario A" first="Alex R" last="Ario">Alex R. Ario</name>
<name sortKey="Kaharuza, Frank" sort="Kaharuza, Frank" uniqKey="Kaharuza F" first="Frank" last="Kaharuza">Frank Kaharuza</name>
<name sortKey="Lali, William Z" sort="Lali, William Z" uniqKey="Lali W" first="William Z" last="Lali">William Z. Lali</name>
<name sortKey="Makumbi, Issa" sort="Makumbi, Issa" uniqKey="Makumbi I" first="Issa" last="Makumbi">Issa Makumbi</name>
<name sortKey="Masiira, Ben" sort="Masiira, Ben" uniqKey="Masiira B" first="Ben" last="Masiira">Ben Masiira</name>
<name sortKey="Matovu, Joseph K B" sort="Matovu, Joseph K B" uniqKey="Matovu J" first="Joseph K B" last="Matovu">Joseph K B. Matovu</name>
<name sortKey="Matwale, Gabriel K" sort="Matwale, Gabriel K" uniqKey="Matwale G" first="Gabriel K" last="Matwale">Gabriel K. Matwale</name>
<name sortKey="Musenero, Monica" sort="Musenero, Monica" uniqKey="Musenero M" first="Monica" last="Musenero">Monica Musenero</name>
<name sortKey="Nabukenya, Immaculate" sort="Nabukenya, Immaculate" uniqKey="Nabukenya I" first="Immaculate" last="Nabukenya">Immaculate Nabukenya</name>
<name sortKey="Nanyunja, Miriam" sort="Nanyunja, Miriam" uniqKey="Nanyunja M" first="Miriam" last="Nanyunja">Miriam Nanyunja</name>
<name sortKey="Zhu, Bao Ping" sort="Zhu, Bao Ping" uniqKey="Zhu B" first="Bao-Ping" last="Zhu">Bao-Ping Zhu</name>
</country>
</tree>
</affiliations>
</record>
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