Comparison of quality of life, satisfaction with surgery and shoulder-arm morbidity in breast cancer survivors submitted to breast-conserving therapy or mastectomy followed by immediate breast reconstruction
Identifieur interne : 003D59 ( Pmc/Curation ); précédent : 003D58; suivant : 003D60Comparison of quality of life, satisfaction with surgery and shoulder-arm morbidity in breast cancer survivors submitted to breast-conserving therapy or mastectomy followed by immediate breast reconstruction
Auteurs : Renata Freitas-Silva [Brésil] ; Délio Marques Conde [Brésil] ; Ruffo De Freitas-Júnior [Brésil] ; Edson Zangiacomi Martinez [Brésil]Source :
- Clinics [ 1807-5932 ] ; 2010.
Abstract
This study was designed to compare the prevalence of shoulder-arm morbidity, patient satisfaction with surgery and the quality of life of women submitted to breast-conserving therapy or modified radical mastectomy and immediate breast reconstruction.
This study was a cross-sectional study of women who underwent breast-conserving therapy (n = 44) or modified radical mastectomy and immediate breast reconstruction (n = 26). Quality of life was evaluated with the SF-36 Health Survey Questionnaire.
No differences were found in the prevalence of lymphedema. The movements that were most commonly affected by these procedures were abduction, flexion and external rotation. When the two groups were compared, however, we only found a statistically significant difference for the prevalence of restricted internal rotation, which occurred in 32% of women in the breast-conserving therapy group and 12% of those in the modified radical mastectomy and immediate breast reconstruction group (OR: 7.23; p = 0.03 following adjustment for potential confounding factors). No difference in quality of life or satisfaction with surgery was found between the two groups.
These data suggest that the type of surgery did not affect the occurrence of lymphedema. Breast-conserving therapy, however, increased the risk of shoulder movement limitation. No differences were found between the two surgical techniques with respect to quality of life or satisfaction with surgery.
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DOI: 10.1590/S1807-59322010000800009
PubMed: 20835555
PubMed Central: 2933125
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Comparison of quality of life, satisfaction with surgery and shoulder-arm morbidity in breast cancer survivors submitted to breast-conserving therapy or mastectomy followed by immediate breast reconstruction</title><author><name sortKey="Freitas Silva, Renata" sort="Freitas Silva, Renata" uniqKey="Freitas Silva R" first="Renata" last="Freitas-Silva">Renata Freitas-Silva</name><affiliation wicri:level="1"><nlm:aff id="af1-cln_65p781">Department of Gynecology and Obstetrics, Universidade Federal de Goiás (UFG), Goiânia/GO, Brasil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Gynecology and Obstetrics, Universidade Federal de Goiás (UFG), Goiânia/GO</wicri:regionArea></affiliation></author><author><name sortKey="Conde, Delio Marques" sort="Conde, Delio Marques" uniqKey="Conde D" first="Délio Marques" last="Conde">Délio Marques Conde</name><affiliation wicri:level="1"><nlm:aff id="af2-cln_65p781">Breast Service, Hospital Materno Infantil (HMI), Goiânia/GO, Brasil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Breast Service, Hospital Materno Infantil (HMI), Goiânia/GO</wicri:regionArea></affiliation></author><author><name sortKey="De Freitas Junior, Ruffo" sort="De Freitas Junior, Ruffo" uniqKey="De Freitas Junior R" first="Ruffo" last="De Freitas-Júnior">Ruffo De Freitas-Júnior</name><affiliation wicri:level="1"><nlm:aff id="af1-cln_65p781">Department of Gynecology and Obstetrics, Universidade Federal de Goiás (UFG), Goiânia/GO, Brasil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Gynecology and Obstetrics, Universidade Federal de Goiás (UFG), Goiânia/GO</wicri:regionArea></affiliation></author><author><name sortKey="Martinez, Edson Zangiacomi" sort="Martinez, Edson Zangiacomi" uniqKey="Martinez E" first="Edson Zangiacomi" last="Martinez">Edson Zangiacomi Martinez</name><affiliation wicri:level="1"><nlm:aff id="af3-cln_65p781">Department of Social Medicine, Universidade de São Paulo (USP), Ribeirão Preto/SP, Brasil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Social Medicine, Universidade de São Paulo (USP), Ribeirão Preto/SP</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">20835555</idno><idno type="pmc">2933125</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933125</idno><idno type="RBID">PMC:2933125</idno><idno type="doi">10.1590/S1807-59322010000800009</idno><date when="2010">2010</date><idno type="wicri:Area/Pmc/Corpus">003D60</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003D60</idno><idno type="wicri:Area/Pmc/Curation">003D59</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">003D59</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Comparison of quality of life, satisfaction with surgery and shoulder-arm morbidity in breast cancer survivors submitted to breast-conserving therapy or mastectomy followed by immediate breast reconstruction</title><author><name sortKey="Freitas Silva, Renata" sort="Freitas Silva, Renata" uniqKey="Freitas Silva R" first="Renata" last="Freitas-Silva">Renata Freitas-Silva</name><affiliation wicri:level="1"><nlm:aff id="af1-cln_65p781">Department of Gynecology and Obstetrics, Universidade Federal de Goiás (UFG), Goiânia/GO, Brasil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Gynecology and Obstetrics, Universidade Federal de Goiás (UFG), Goiânia/GO</wicri:regionArea></affiliation></author><author><name sortKey="Conde, Delio Marques" sort="Conde, Delio Marques" uniqKey="Conde D" first="Délio Marques" last="Conde">Délio Marques Conde</name><affiliation wicri:level="1"><nlm:aff id="af2-cln_65p781">Breast Service, Hospital Materno Infantil (HMI), Goiânia/GO, Brasil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Breast Service, Hospital Materno Infantil (HMI), Goiânia/GO</wicri:regionArea></affiliation></author><author><name sortKey="De Freitas Junior, Ruffo" sort="De Freitas Junior, Ruffo" uniqKey="De Freitas Junior R" first="Ruffo" last="De Freitas-Júnior">Ruffo De Freitas-Júnior</name><affiliation wicri:level="1"><nlm:aff id="af1-cln_65p781">Department of Gynecology and Obstetrics, Universidade Federal de Goiás (UFG), Goiânia/GO, Brasil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Gynecology and Obstetrics, Universidade Federal de Goiás (UFG), Goiânia/GO</wicri:regionArea></affiliation></author><author><name sortKey="Martinez, Edson Zangiacomi" sort="Martinez, Edson Zangiacomi" uniqKey="Martinez E" first="Edson Zangiacomi" last="Martinez">Edson Zangiacomi Martinez</name><affiliation wicri:level="1"><nlm:aff id="af3-cln_65p781">Department of Social Medicine, Universidade de São Paulo (USP), Ribeirão Preto/SP, Brasil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Social Medicine, Universidade de São Paulo (USP), Ribeirão Preto/SP</wicri:regionArea></affiliation></author></analytic><series><title level="j">Clinics</title><idno type="ISSN">1807-5932</idno><idno type="eISSN">1980-5322</idno><imprint><date when="2010">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>OBJECTIVES:</title><p>This study was designed to compare the prevalence of shoulder-arm morbidity, patient satisfaction with surgery and the quality of life of women submitted to breast-conserving therapy or modified radical mastectomy and immediate breast reconstruction.</p></sec><sec><title>METHODS:</title><p>This study was a cross-sectional study of women who underwent breast-conserving therapy (n = 44) or modified radical mastectomy and immediate breast reconstruction (n = 26). Quality of life was evaluated with the SF-36 Health Survey Questionnaire.</p></sec><sec><title>RESULTS:</title><p>No differences were found in the prevalence of lymphedema. The movements that were most commonly affected by these procedures were abduction, flexion and external rotation. When the two groups were compared, however, we only found a statistically significant difference for the prevalence of restricted internal rotation, which occurred in 32% of women in the breast-conserving therapy group and 12% of those in the modified radical mastectomy and immediate breast reconstruction group (OR: 7.23; p = 0.03 following adjustment for potential confounding factors). No difference in quality of life or satisfaction with surgery was found between the two groups.</p></sec><sec><title>CONCLUSIONS:</title><p>These data suggest that the type of surgery did not affect the occurrence of lymphedema. Breast-conserving therapy, however, increased the risk of shoulder movement limitation. 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Clinics (Sao Paulo)</journal-id><journal-title-group><journal-title>Clinics</journal-title></journal-title-group><issn pub-type="ppub">1807-5932</issn><issn pub-type="epub">1980-5322</issn><publisher><publisher-name>Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">20835555</article-id><article-id pub-id-type="pmc">2933125</article-id><article-id pub-id-type="doi">10.1590/S1807-59322010000800009</article-id><article-id pub-id-type="publisher-id">cln_65p781</article-id><article-categories><subj-group subj-group-type="heading"><subject>Clinical Science</subject></subj-group></article-categories><title-group><article-title>Comparison of quality of life, satisfaction with surgery and shoulder-arm morbidity in breast cancer survivors submitted to breast-conserving therapy or mastectomy followed by immediate breast reconstruction</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Freitas-Silva</surname><given-names>Renata</given-names></name><xref ref-type="aff" rid="af1-cln_65p781">1</xref></contrib><contrib contrib-type="author"><name><surname>Conde</surname><given-names>Délio Marques</given-names></name><xref ref-type="aff" rid="af2-cln_65p781">2</xref><xref ref-type="corresp" rid="c1-cln_65p781"></xref></contrib><contrib contrib-type="author"><name><surname>de Freitas-Júnior</surname><given-names>Ruffo</given-names></name><xref ref-type="aff" rid="af1-cln_65p781">1</xref></contrib><contrib contrib-type="author"><name><surname>Martinez</surname><given-names>Edson Zangiacomi</given-names></name><xref ref-type="aff" rid="af3-cln_65p781">3</xref></contrib><aff id="af1-cln_65p781"><label>1</label>Department of Gynecology and Obstetrics, Universidade Federal de Goiás (UFG), Goiânia/GO, Brasil</aff><aff id="af2-cln_65p781"><label>2</label>Breast Service, Hospital Materno Infantil (HMI), Goiânia/GO, Brasil</aff><aff id="af3-cln_65p781"><label>3</label>Department of Social Medicine, Universidade de São Paulo (USP), Ribeirão Preto/SP, Brasil</aff></contrib-group><author-notes><corresp id="c1-cln_65p781">E-mail: <email>condedelio@uol.com.br</email> Tel.: <phone>55 62 3209-6151</phone></corresp></author-notes><pub-date pub-type="ppub"><month>8</month><year>2010</year></pub-date><volume>65</volume><issue>8</issue><fpage seq="b">781</fpage><lpage>787</lpage><history><date date-type="received"><day>8</day><month>3</month><year>2010</year></date><date date-type="rev-recd"><day>14</day><month>4</month><year>2010</year></date><date date-type="accepted"><day>11</day><month>5</month><year>2010</year></date></history><permissions><copyright-statement>Copyright © 2010 Hospital das Clínicas da FMUSP</copyright-statement><copyright-year>2010</copyright-year><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc/3.0/"><license-p><pmc-comment>CREATIVE COMMONS</pmc-comment>This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by-nc/3.0/">http://creativecommons.org/licenses/by-nc/3.0/</ext-link>) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions><abstract><sec><title>OBJECTIVES:</title><p>This study was designed to compare the prevalence of shoulder-arm morbidity, patient satisfaction with surgery and the quality of life of women submitted to breast-conserving therapy or modified radical mastectomy and immediate breast reconstruction.</p></sec><sec><title>METHODS:</title><p>This study was a cross-sectional study of women who underwent breast-conserving therapy (n = 44) or modified radical mastectomy and immediate breast reconstruction (n = 26). Quality of life was evaluated with the SF-36 Health Survey Questionnaire.</p></sec><sec><title>RESULTS:</title><p>No differences were found in the prevalence of lymphedema. The movements that were most commonly affected by these procedures were abduction, flexion and external rotation. When the two groups were compared, however, we only found a statistically significant difference for the prevalence of restricted internal rotation, which occurred in 32% of women in the breast-conserving therapy group and 12% of those in the modified radical mastectomy and immediate breast reconstruction group (OR: 7.23; p = 0.03 following adjustment for potential confounding factors). No difference in quality of life or satisfaction with surgery was found between the two groups.</p></sec><sec><title>CONCLUSIONS:</title><p>These data suggest that the type of surgery did not affect the occurrence of lymphedema. Breast-conserving therapy, however, increased the risk of shoulder movement limitation. No differences were found between the two surgical techniques with respect to quality of life or satisfaction with surgery.</p></sec></abstract><kwd-group><kwd>Breast cancer</kwd><kwd>Quality of life</kwd><kwd>Lymphedema</kwd><kwd>Shoulder-arm morbidity, Aesthetic outcome</kwd></kwd-group><counts><page-count count="7"></page-count></counts></article-meta></front><floats-group><table-wrap id="t1-cln_65p781" position="float"><label>Table 1</label><caption><p>Questions used to investigate patient satisfaction with breast cancer surgery.</p></caption><table frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom" rowspan="1" colspan="1">Questions</td><td colspan="7" align="center" valign="bottom" rowspan="1">Answers</td></tr></thead><tbody><tr><td align="left" valign="top" rowspan="1" colspan="1">1. How would you evaluate the aesthetic results of your breast cancer surgery?</td><td align="center" valign="top" rowspan="1" colspan="1">1 dreadful</td><td align="center" valign="top" rowspan="1" colspan="1">2</td><td align="center" valign="top" rowspan="1" colspan="1">3</td><td align="center" valign="top" rowspan="1" colspan="1">4</td><td align="center" valign="top" rowspan="1" colspan="1">5</td><td align="center" valign="top" rowspan="1" colspan="1">6</td><td align="center" valign="top" rowspan="1" colspan="1">7 excellent</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="center" valign="top" rowspan="1" colspan="1">not at all</td><td colspan="2" align="center" valign="top" rowspan="1">slightly</td><td colspan="2" align="center" valign="top" rowspan="1">moderately</td><td colspan="2" align="center" valign="top" rowspan="1">very much so</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">2. In your opinion, did breast cancer surgery result in a substantial change to your physical appearance?</td><td align="center" valign="top" rowspan="1" colspan="1">1</td><td colspan="2" align="center" valign="top" rowspan="1">2</td><td colspan="2" align="center" valign="top" rowspan="1">3</td><td colspan="2" align="center" valign="top" rowspan="1">4</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">3. Has your physical appearance caused you any emotional stress in your relationship with your partner, family or close friends?</td><td align="center" valign="top" rowspan="1" colspan="1">1</td><td colspan="2" align="center" valign="top" rowspan="1">2</td><td colspan="2" align="center" valign="top" rowspan="1">3</td><td colspan="2" align="center" valign="top" rowspan="1">4</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">4. Is your everyday life still impaired as a result of the breast cancer surgery?</td><td align="center" valign="top" rowspan="1" colspan="1">1</td><td colspan="2" align="center" valign="top" rowspan="1">2</td><td colspan="2" align="center" valign="top" rowspan="1">3</td><td colspan="2" align="center" valign="top" rowspan="1">4</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">5. Do you regret your choice of breast cancer surgery (BCT or MRM+IBR)?</td><td align="center" valign="top" rowspan="1" colspan="1">1</td><td colspan="2" align="center" valign="top" rowspan="1">2</td><td colspan="2" align="center" valign="top" rowspan="1">3</td><td colspan="2" align="center" valign="top" rowspan="1">4</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">6. Do you fear a recurrence of breast cancer?</td><td align="center" valign="top" rowspan="1" colspan="1">1</td><td colspan="2" align="center" valign="top" rowspan="1">2</td><td colspan="2" align="center" valign="top" rowspan="1">3</td><td colspan="2" align="center" valign="top" rowspan="1">4</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">7. In hindsight, would you opt for a different surgical treatment of breast cancer?</td><td align="center" valign="top" rowspan="1" colspan="1">Yes</td><td colspan="2" align="center" valign="top" rowspan="1">-</td><td colspan="2" align="center" valign="top" rowspan="1">-</td><td colspan="2" align="center" valign="top" rowspan="1">No</td></tr></tbody></table></table-wrap><table-wrap id="t2-cln_65p781" position="float"><label>Table 2</label><caption><p>Sociodemographic and clinical features of women with breast cancer submitted to MRM+IBR(n = 26) or BCT (n = 44).</p></caption><table frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom" rowspan="1" colspan="1">Characteristic</td><td align="center" valign="bottom" rowspan="1" colspan="1">MRM+IBR</td><td align="center" valign="bottom" rowspan="1" colspan="1">BCT</td><td align="center" valign="bottom" rowspan="1" colspan="1">p-value</td></tr></thead><tbody><tr><td align="left" valign="top" rowspan="1" colspan="1">Age (years)<xref ref-type="table-fn" rid="tfn2-cln_65p781">*</xref></td><td align="char" char="(" valign="top" rowspan="1" colspan="1">47.6 (7.4)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">50.2 (7.3)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">0.16<xref ref-type="table-fn" rid="tfn4-cln_65p781">1</xref></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Education level (years of schooling)<xref ref-type="table-fn" rid="tfn2-cln_65p781">*</xref></td><td align="char" char="(" valign="top" rowspan="1" colspan="1">7.6 (3.3)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">6.3 (3.5)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">0.14<xref ref-type="table-fn" rid="tfn4-cln_65p781">1</xref></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Race/ethnicity<xref ref-type="table-fn" rid="tfn3-cln_65p781">#</xref></td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="char" char="(" valign="top" rowspan="1" colspan="1">0.28<xref ref-type="table-fn" rid="tfn5-cln_65p781">2</xref></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> White</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">7 (27)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">15 (34)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> Other</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">19 (73)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">29 (66)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Marital status<xref ref-type="table-fn" rid="tfn3-cln_65p781">#</xref></td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="char" char="(" valign="top" rowspan="1" colspan="1">0.83<xref ref-type="table-fn" rid="tfn5-cln_65p781">2</xref></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> Single</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">5 (19)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">8 (18)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> Married</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">10 (38)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">21 (48)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> Cohabiting</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">4 (15)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">7 (16)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> Separated/divorced</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">3 (12)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">2 (5)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Smoker<xref ref-type="table-fn" rid="tfn3-cln_65p781">#</xref></td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="char" char="(" valign="top" rowspan="1" colspan="1">0.53<xref ref-type="table-fn" rid="tfn5-cln_65p781">2</xref></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> yes</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">0 (0)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">2 (5)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> no</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">26 (100)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">42 (95)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Monthly family income ($US)<xref ref-type="table-fn" rid="tfn2-cln_65p781">*</xref></td><td align="char" char="(" valign="top" rowspan="1" colspan="1">430.45 (241.75)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">490.31 (432.22)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">0.49<xref ref-type="table-fn" rid="tfn4-cln_65p781">1</xref></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Employment status<xref ref-type="table-fn" rid="tfn3-cln_65p781">#</xref></td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="char" char="(" valign="top" rowspan="1" colspan="1">1.00<xref ref-type="table-fn" rid="tfn5-cln_65p781">2</xref></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> In paid employment</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">7 (27)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">11 (25)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> Housewife</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">16 (62)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">28 (64)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> Retired</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">3 (12)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">5 (11)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Body index mass (kg/m<xref ref-type="table-fn" rid="tfn5-cln_65p781">2</xref>)<xref ref-type="table-fn" rid="tfn3-cln_65p781">#</xref></td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="char" char="(" valign="top" rowspan="1" colspan="1">0.17<xref ref-type="table-fn" rid="tfn5-cln_65p781">2</xref></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> <25</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">12 (48)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">13 (30)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> 25–30</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">10 (40)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">18 (41)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> ≥30</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">3 (12)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">13 (30)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Menopausal status<xref ref-type="table-fn" rid="tfn3-cln_65p781">#</xref></td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="char" char="(" valign="top" rowspan="1" colspan="1">0.41<xref ref-type="table-fn" rid="tfn5-cln_65p781">2</xref></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> Premenopausal</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">4 (15)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">3 (7)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> Postmenopausal</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">22 (85)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">41 (93)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr></tbody></table><table-wrap-foot><fn id="tfn2-cln_65p781"><label>*</label><p>Values expressed as means (± SD)</p></fn><fn id="tfn3-cln_65p781"><label>#</label><p>Values expressed as N (%)</p></fn><fn id="tfn4-cln_65p781"><label>1</label><p>Student's <italic>t</italic> test</p></fn><fn id="tfn5-cln_65p781"><label>2</label><p>Fisher's exact test</p></fn></table-wrap-foot></table-wrap><table-wrap id="t3-cln_65p781" position="float"><label>Table 3</label><caption><p>Disease and treatment-related features of women with breast cancer submitted to MRM+IBR (n = 26) or BCT (n = 44).</p></caption><table frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom" rowspan="1" colspan="1">Characteristics</td><td align="center" valign="bottom" rowspan="1" colspan="1">MRM+IBR</td><td align="center" valign="bottom" rowspan="1" colspan="1">BCT</td><td align="center" valign="bottom" rowspan="1" colspan="1">p-value</td></tr></thead><tbody><tr><td align="left" valign="top" rowspan="1" colspan="1">Age at surgery (years)<xref ref-type="table-fn" rid="tfn7-cln_65p781">*</xref></td><td align="char" char="(" valign="top" rowspan="1" colspan="1">45.0 (7.4)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">46.9 (7.0)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">0.29<xref ref-type="table-fn" rid="tfn9-cln_65p781">1</xref></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Time since surgery (months)<xref ref-type="table-fn" rid="tfn7-cln_65p781">*</xref></td><td align="char" char="(" valign="top" rowspan="1" colspan="1">31.5 (26.7)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">44.3 (29.5)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">0.07<xref ref-type="table-fn" rid="tfn9-cln_65p781">1</xref></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Histology<xref ref-type="table-fn" rid="tfn8-cln_65p781">#</xref></td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="char" char="(" valign="top" rowspan="1" colspan="1">0.34<xref ref-type="table-fn" rid="tfn10-cln_65p781">2</xref></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> Invasive ductal carcinoma</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">22 (85)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">39 (89)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> Invasive lobular carcinoma</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">4 (15)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">3 (7)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> Others</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">0 (0)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">2 (5)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Number of lymph nodes removed <xref ref-type="table-fn" rid="tfn7-cln_65p781">*</xref></td><td align="char" char="(" valign="top" rowspan="1" colspan="1">17.2 (4.4)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">15.4 (6.5)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">0.16<xref ref-type="table-fn" rid="tfn9-cln_65p781">1</xref></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Number of affected lymph nodes<xref ref-type="table-fn" rid="tfn7-cln_65p781">*</xref></td><td align="char" char="(" valign="top" rowspan="1" colspan="1">1.8 (3.6)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">2.4 (6.1)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">0.62<xref ref-type="table-fn" rid="tfn9-cln_65p781">1</xref></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Stage<xref ref-type="table-fn" rid="tfn8-cln_65p781">#</xref></td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="char" char="(" valign="top" rowspan="1" colspan="1">0.02<xref ref-type="table-fn" rid="tfn10-cln_65p781">2</xref></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> I</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">3 (12)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">17 (39)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> II</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">19 (73)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">25 (57)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> III</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">4 (15)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">2 (5)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Radiotherapy<xref ref-type="table-fn" rid="tfn8-cln_65p781">#</xref></td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="char" char="(" valign="top" rowspan="1" colspan="1"><0.01<xref ref-type="table-fn" rid="tfn10-cln_65p781">2</xref></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> Yes</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">10 (38)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">44 (100)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> No</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">16 (62)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">0 (0)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Adjuvant chemotherapy<xref ref-type="table-fn" rid="tfn8-cln_65p781">#</xref></td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="char" char="(" valign="top" rowspan="1" colspan="1">0.13<xref ref-type="table-fn" rid="tfn10-cln_65p781">2</xref></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> Yes</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">14 (54)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">32 (73)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> No</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">12 (46)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">12 (27)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Tamoxifen<xref ref-type="table-fn" rid="tfn8-cln_65p781">#</xref></td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="char" char="(" valign="top" rowspan="1" colspan="1">0.53<xref ref-type="table-fn" rid="tfn10-cln_65p781">2</xref></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> Yes</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">20 (77)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">37 (84)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"> No</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">6 (23)</td><td align="char" char="(" valign="top" rowspan="1" colspan="1">7 (16)</td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr></tbody></table><table-wrap-foot><fn id="tfn7-cln_65p781"><label>*</label><p>Values expressed as means (±SD)</p></fn><fn id="tfn8-cln_65p781"><label>#</label><p>Values expressed as N (%)</p></fn><fn id="tfn9-cln_65p781"><label>1</label><p>Student's <italic>t</italic> test</p></fn><fn id="tfn10-cln_65p781"><label>2</label><p>Fisher's exact test</p></fn></table-wrap-foot></table-wrap><table-wrap id="t4-cln_65p781" position="float"><label>Table 4</label><caption><p>Prevalence of lymphedema and restriction of shoulder movement in breast cancer survivors submitted to MRM+IBR (n = 26) or BCT (n = 44).</p></caption><table frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom" rowspan="1" colspan="1">Variables</td><td align="center" valign="bottom" rowspan="1" colspan="1">Group</td><td align="center" valign="bottom" rowspan="1" colspan="1">n (%)</td><td align="center" valign="bottom" rowspan="1" colspan="1">Adjusted OR<xref ref-type="table-fn" rid="tfn12-cln_65p781">a</xref> (95% CI)</td><td align="center" valign="bottom" rowspan="1" colspan="1">Adjusted p-value<xref ref-type="table-fn" rid="tfn12-cln_65p781">a</xref></td></tr></thead><tbody><tr><td align="left" valign="top" rowspan="1" colspan="1">Lymphedema</td><td align="left" valign="top" rowspan="1" colspan="1">MRM+IBRBCT</td><td align="center" valign="top" rowspan="1" colspan="1">3 (12)8 (18)</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.51 (0.02–10.1)</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.66</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Abduction</td><td align="left" valign="top" rowspan="1" colspan="1">MRM+IBRBCT</td><td align="center" valign="top" rowspan="1" colspan="1">18 (69)24 (55)</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.17 (0.08–3.37)</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.25</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Flexion</td><td align="left" valign="top" rowspan="1" colspan="1">MRM+IBRBCT</td><td align="center" valign="top" rowspan="1" colspan="1">17 (65)33 (35)</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.50 (0.02–9.91)</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.65</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Extension</td><td align="left" valign="top" rowspan="1" colspan="1">MRM+IBRBCT</td><td align="center" valign="top" rowspan="1" colspan="1">1 (4)9 (30)</td><td align="char" char="." valign="top" rowspan="1" colspan="1">3.88 (0.05–291)</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.12</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Internal rotation</td><td align="left" valign="top" rowspan="1" colspan="1">MRM+IBRBCT</td><td align="center" valign="top" rowspan="1" colspan="1">3 (12)14 (32)</td><td align="char" char="." valign="top" rowspan="1" colspan="1">7.23 (1.28–17.1)</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.03</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">External rotation</td><td align="left" valign="top" rowspan="1" colspan="1">MRM+IBRBCT</td><td align="center" valign="top" rowspan="1" colspan="1">15 (58)16 (36)</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.20 (0.03–1.70)</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.14</td></tr></tbody></table><table-wrap-foot><fn id="tfn12-cln_65p781"><label>a</label><p>Adjusted for age, BMI, time since surgery, clinical stage, chemotherapy, radiotherapy, number of lymph nodes removed, presence of affected lymph nodes and current use of tamoxifen, using unconditional logistic regression models.</p></fn></table-wrap-foot></table-wrap><table-wrap id="t5-cln_65p781" position="float"><label>Table 5</label><caption><p>Comparison between the median scores of patient satisfaction with surgery in women with breast cancer submitted to MRM+IBR (n = 26) or BCT (n = 44).</p></caption><table frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom" rowspan="1" colspan="1">Variables</td><td align="center" valign="bottom" rowspan="1" colspan="1">Group</td><td align="center" valign="bottom" rowspan="1" colspan="1">Median</td><td align="center" valign="bottom" rowspan="1" colspan="1">Percentiles</td><td align="center" valign="bottom" rowspan="1" colspan="1">Crude</td><td align="center" valign="bottom" rowspan="1" colspan="1">Adjusted</td></tr><tr><td align="left" valign="bottom" rowspan="1" colspan="1"></td><td align="center" valign="bottom" rowspan="1" colspan="1"></td><td align="center" valign="bottom" rowspan="1" colspan="1"></td><td align="center" valign="bottom" rowspan="1" colspan="1">25–75%</td><td align="center" valign="bottom" rowspan="1" colspan="1">p-value</td><td align="center" valign="bottom" rowspan="1" colspan="1">p-value<xref ref-type="table-fn" rid="tfn14-cln_65p781">*</xref></td></tr></thead><tbody><tr><td align="left" valign="top" rowspan="1" colspan="1">Aesthetic outcome</td><td align="left" valign="top" rowspan="1" colspan="1">MRM+IBR</td><td align="char" char="." valign="top" rowspan="1" colspan="1">66.7</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">66.7–83.3</td><td align="char" char="." valign="top" rowspan="1" colspan="1">1.0</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.88</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1">BCT</td><td align="char" char="." valign="top" rowspan="1" colspan="1">75.0</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">50.0–83.3</td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Change in physical appearance</td><td align="left" valign="top" rowspan="1" colspan="1">MRM+IBR</td><td align="char" char="." valign="top" rowspan="1" colspan="1">33.3</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">0–66.7</td><td align="char" char="." valign="top" rowspan="1" colspan="1">1.0</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.95</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1">BCT</td><td align="char" char="." valign="top" rowspan="1" colspan="1">33.3</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">0–66.7</td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Disturbed by appearance</td><td align="left" valign="top" rowspan="1" colspan="1">MRM+IBR</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">0–0</td><td align="char" char="." valign="top" rowspan="1" colspan="1">1.0</td><td align="char" char="." valign="top" rowspan="1" colspan="1">1.0</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1">BCT</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">0–33.3</td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Impairment to daily life</td><td align="left" valign="top" rowspan="1" colspan="1">MRM+IBR</td><td align="char" char="." valign="top" rowspan="1" colspan="1">33.3</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">0–66.7</td><td align="char" char="." valign="top" rowspan="1" colspan="1">1.0</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.50</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1">BCT</td><td align="char" char="." valign="top" rowspan="1" colspan="1">33.3</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">0–66.7</td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Regret</td><td align="left" valign="top" rowspan="1" colspan="1">MRM+IBR</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">0–0</td><td align="char" char="." valign="top" rowspan="1" colspan="1">1.0</td><td align="char" char="." valign="top" rowspan="1" colspan="1">1.0</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1">BCT</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">0–0</td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Fear of recurrence</td><td align="left" valign="top" rowspan="1" colspan="1">MRM+IBR</td><td align="char" char="." valign="top" rowspan="1" colspan="1">66.7</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">33.3–100</td><td align="char" char="." valign="top" rowspan="1" colspan="1">1.0</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.70</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1">BCT</td><td align="char" char="." valign="top" rowspan="1" colspan="1">66.7</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">33.3–100</td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr></tbody></table><table-wrap-foot><fn id="tfn14-cln_65p781"><label>*</label><p>Comparison between medians using least absolute value regression with adjustment for age, BMI, time since surgery, clinical stage, chemotherapy, radiotherapy, lymphedema, number of removed lymph nodes, presence of affected lymph nodes and current use of tamoxifen.</p></fn></table-wrap-foot></table-wrap><table-wrap id="t6-cln_65p781" position="float"><label>Table 6</label><caption><p>Comparison between the median SF-36 scores for women with breast cancer submitted to MRM+IBR (n = 26) or BCT (n = 44).</p></caption><table frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom" rowspan="1" colspan="1">SF-36 domains</td><td align="center" valign="bottom" rowspan="1" colspan="1">Group</td><td align="center" valign="bottom" rowspan="1" colspan="1">Median</td><td align="center" valign="bottom" rowspan="1" colspan="1">Percentiles</td><td align="center" valign="bottom" rowspan="1" colspan="1">Crude</td><td align="center" valign="bottom" rowspan="1" colspan="1">Adjusted</td></tr><tr><td align="left" valign="bottom" rowspan="1" colspan="1"></td><td align="center" valign="bottom" rowspan="1" colspan="1"></td><td align="center" valign="bottom" rowspan="1" colspan="1"></td><td align="center" valign="bottom" rowspan="1" colspan="1">25–75%</td><td align="center" valign="bottom" rowspan="1" colspan="1">p-value</td><td align="center" valign="bottom" rowspan="1" colspan="1">p-value<xref ref-type="table-fn" rid="tfn16-cln_65p781">*</xref></td></tr></thead><tbody><tr><td align="left" valign="top" rowspan="1" colspan="1">Physical functioning</td><td align="left" valign="top" rowspan="1" colspan="1">MRM+IBR</td><td align="char" char="." valign="top" rowspan="1" colspan="1">72.5</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">65.0–85.0</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.23</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.16</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1">BCT</td><td align="char" char="." valign="top" rowspan="1" colspan="1">62.5</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">40.0–80.0</td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Physical role functioning</td><td align="left" valign="top" rowspan="1" colspan="1">MRM+IBR</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">0–50.0</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.28</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.55</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1">BCT</td><td align="char" char="." valign="top" rowspan="1" colspan="1">25.0</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">0–75.0</td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Emotional role functioning</td><td align="left" valign="top" rowspan="1" colspan="1">MRM+IBR</td><td align="char" char="." valign="top" rowspan="1" colspan="1">100</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">33.3–100</td><td align="char" char="." valign="top" rowspan="1" colspan="1">1.0</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.44</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1">BCT</td><td align="char" char="." valign="top" rowspan="1" colspan="1">100</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">0–100</td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Bodily pain</td><td align="left" valign="top" rowspan="1" colspan="1">MRM+IBR</td><td align="char" char="." valign="top" rowspan="1" colspan="1">51.0</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">30.0–64.5</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.87</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.48</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1">BCT</td><td align="char" char="." valign="top" rowspan="1" colspan="1">51.5</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">34.2–72.0</td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Vitality</td><td align="left" valign="top" rowspan="1" colspan="1">MRM+IBR</td><td align="char" char="." valign="top" rowspan="1" colspan="1">72.5</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">50.0–90.0</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.38</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.56</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1">BCT</td><td align="char" char="." valign="top" rowspan="1" colspan="1">67.5</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">51.2–78.8</td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Mental health</td><td align="left" valign="top" rowspan="1" colspan="1">MRM+IBR</td><td align="char" char="." valign="top" rowspan="1" colspan="1">72.0</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">52.0–81.0</td><td align="char" char="." valign="top" rowspan="1" colspan="1">1.0</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.95</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1">BCT</td><td align="char" char="." valign="top" rowspan="1" colspan="1">74.0</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">57.0–84.0</td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Social role functioning</td><td align="left" valign="top" rowspan="1" colspan="1">MRM+IBR</td><td align="char" char="." valign="top" rowspan="1" colspan="1">100</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">59.3–100</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.47</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.94</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1">BCT</td><td align="char" char="." valign="top" rowspan="1" colspan="1">87.5</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">37.5–100</td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">General health perceptions</td><td align="left" valign="top" rowspan="1" colspan="1">MRM+IBR</td><td align="char" char="." valign="top" rowspan="1" colspan="1">63.5</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">60.0–72.7</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.37</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.95</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1">BCT</td><td align="char" char="." valign="top" rowspan="1" colspan="1">60.0</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">45.5–77.0</td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Physical component summary</td><td align="left" valign="top" rowspan="1" colspan="1">MRM+IBR</td><td align="char" char="." valign="top" rowspan="1" colspan="1">40.7</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">34.1–49.4</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.88</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.76</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1">BCT</td><td align="char" char="." valign="top" rowspan="1" colspan="1">41.4</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">34.0–48.1</td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1">Mental component summary</td><td align="left" valign="top" rowspan="1" colspan="1">MRM+IBR</td><td align="char" char="." valign="top" rowspan="1" colspan="1">51.2</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">45.2–58.1</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.99</td><td align="char" char="." valign="top" rowspan="1" colspan="1">0.58</td></tr><tr><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1">BCT</td><td align="char" char="." valign="top" rowspan="1" colspan="1">51.1</td><td align="char" char="--" valign="top" rowspan="1" colspan="1">38.3–59.2</td><td align="left" valign="top" rowspan="1" colspan="1"></td><td align="left" valign="top" rowspan="1" colspan="1"></td></tr></tbody></table><table-wrap-foot><fn id="tfn16-cln_65p781"><label>*</label><p>Comparison between medians using least absolute value regression with adjustment for age, BMI, duration of surgery, clinical stage, chemotherapy, radiotherapy, lymphedema, number of removed lymph nodes, presence of affected lymph nodes and current use of tamoxifen.</p></fn></table-wrap-foot></table-wrap></floats-group></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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