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<fileDesc>
<titleStmt>
<title xml:lang="en">Lymph Node Fibrosis in a Case of Primary Lymphoedema- A Report of Two Cases</title>
<author>
<name sortKey="Masamatti, Smitha Surendra" sort="Masamatti, Smitha Surendra" uniqKey="Masamatti S" first="Smitha Surendra" last="Masamatti">Smitha Surendra Masamatti</name>
<affiliation>
<nlm:aff id="aff1"> Assistant Professor, Department of Pathology,
<institution>Sapthagiri Medical College and Hospital</institution>
,
<addr-line>Bangalore, Karnataka, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Narasimha, Aparna" sort="Narasimha, Aparna" uniqKey="Narasimha A" first="Aparna" last="Narasimha">Aparna Narasimha</name>
<affiliation>
<nlm:aff id="aff2"> Professor, Department of Pathology,
<institution>Sapthagiri Medical College and Hospital</institution>
,
<addr-line>Bangalore, Karnataka, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Janardhan, Jayalakshmi Valligari" sort="Janardhan, Jayalakshmi Valligari" uniqKey="Janardhan J" first="Jayalakshmi Valligari" last="Janardhan">Jayalakshmi Valligari Janardhan</name>
<affiliation>
<nlm:aff id="aff3"> Tutor, Department of Pathology,
<institution>Sapthagiri Medical College and Hospital</institution>
,
<addr-line>Bangalore, Karnataka, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Chowdappa, Vijaya" sort="Chowdappa, Vijaya" uniqKey="Chowdappa V" first="Vijaya" last="Chowdappa">Vijaya Chowdappa</name>
<affiliation>
<nlm:aff id="aff4"> Head of the Department, Department of Pathology,
<institution>Sapthagiri Medical College and Hospital</institution>
,
<addr-line>Bangalore, Karnataka, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
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<idno type="wicri:source">PMC</idno>
<idno type="pmid">27790446</idno>
<idno type="pmc">5071946</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071946</idno>
<idno type="RBID">PMC:5071946</idno>
<idno type="doi">10.7860/JCDR/2016/19528.8561</idno>
<date when="2016">2016</date>
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<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002052</idno>
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<title xml:lang="en" level="a" type="main">Lymph Node Fibrosis in a Case of Primary Lymphoedema- A Report of Two Cases</title>
<author>
<name sortKey="Masamatti, Smitha Surendra" sort="Masamatti, Smitha Surendra" uniqKey="Masamatti S" first="Smitha Surendra" last="Masamatti">Smitha Surendra Masamatti</name>
<affiliation>
<nlm:aff id="aff1"> Assistant Professor, Department of Pathology,
<institution>Sapthagiri Medical College and Hospital</institution>
,
<addr-line>Bangalore, Karnataka, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Narasimha, Aparna" sort="Narasimha, Aparna" uniqKey="Narasimha A" first="Aparna" last="Narasimha">Aparna Narasimha</name>
<affiliation>
<nlm:aff id="aff2"> Professor, Department of Pathology,
<institution>Sapthagiri Medical College and Hospital</institution>
,
<addr-line>Bangalore, Karnataka, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Janardhan, Jayalakshmi Valligari" sort="Janardhan, Jayalakshmi Valligari" uniqKey="Janardhan J" first="Jayalakshmi Valligari" last="Janardhan">Jayalakshmi Valligari Janardhan</name>
<affiliation>
<nlm:aff id="aff3"> Tutor, Department of Pathology,
<institution>Sapthagiri Medical College and Hospital</institution>
,
<addr-line>Bangalore, Karnataka, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Chowdappa, Vijaya" sort="Chowdappa, Vijaya" uniqKey="Chowdappa V" first="Vijaya" last="Chowdappa">Vijaya Chowdappa</name>
<affiliation>
<nlm:aff id="aff4"> Head of the Department, Department of Pathology,
<institution>Sapthagiri Medical College and Hospital</institution>
,
<addr-line>Bangalore, Karnataka, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Journal of Clinical and Diagnostic Research : JCDR</title>
<idno type="ISSN">2249-782X</idno>
<idno type="eISSN">0973-709X</idno>
<imprint>
<date when="2016">2016</date>
</imprint>
</series>
</biblStruct>
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<textClass></textClass>
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<front>
<div type="abstract" xml:lang="en">
<p>Lymphoedema can be classified into primary and secondary. Primary lymphoedema arise in patients where the cause is not known. Secondary lymphoedema are those in which the lymph system has been damaged by some well recognised pathological process, such as extensive malignancy, filariasis, radiation etc. The changes may occur either in the lymph node, or in lymph vessels or both. The clinical evolution and the prognosis of the oedema in the limb involved will depend on the extension and evolution of these lesions. The degree of fibrosis and its distribution in lymph node play an important role on the prognosis, clinical course and treatment of the patient. Hence pathologist should be aware of the microscopic distribution and patterns of lymph node fibrosis in primary lymphoedema. We hereby report two cases- a 50-year-old male diabetic patient and a 35-year-old male patient presenting with varicose veins, lymphoedema showing lymph node fibrosis.</p>
</div>
</front>
</TEI>
<pmc article-type="case-report">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">J Clin Diagn Res</journal-id>
<journal-id journal-id-type="iso-abbrev">J Clin Diagn Res</journal-id>
<journal-id journal-id-type="hwp">Journal of Clinical and Diagnostic Research</journal-id>
<journal-id journal-id-type="publisher-id">JCDR</journal-id>
<journal-title-group>
<journal-title>Journal of Clinical and Diagnostic Research : JCDR</journal-title>
</journal-title-group>
<issn pub-type="ppub">2249-782X</issn>
<issn pub-type="epub">0973-709X</issn>
<publisher>
<publisher-name>JCDR Research and Publications (P) Limited</publisher-name>
<publisher-loc>Delhi, India</publisher-loc>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">27790446</article-id>
<article-id pub-id-type="pmc">5071946</article-id>
<article-id pub-id-type="doi">10.7860/JCDR/2016/19528.8561</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Pathology Section</subject>
<subj-group subj-group-type="heading">
<subject>Case Report</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Lymph Node Fibrosis in a Case of Primary Lymphoedema- A Report of Two Cases</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Masamatti</surname>
<given-names>Smitha Surendra</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Narasimha</surname>
<given-names>Aparna</given-names>
</name>
<xref ref-type="aff" rid="aff2">2</xref>
<xref ref-type="corresp" rid="cor1"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Janardhan</surname>
<given-names>Jayalakshmi Valligari</given-names>
</name>
<xref ref-type="aff" rid="aff3">3</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Chowdappa</surname>
<given-names>Vijaya</given-names>
</name>
<xref ref-type="aff" rid="aff4">4</xref>
</contrib>
</contrib-group>
<aff id="aff1">
<label>1</label>
Assistant Professor, Department of Pathology,
<institution>Sapthagiri Medical College and Hospital</institution>
,
<addr-line>Bangalore, Karnataka, India</addr-line>
.</aff>
<aff id="aff2">
<label>2</label>
Professor, Department of Pathology,
<institution>Sapthagiri Medical College and Hospital</institution>
,
<addr-line>Bangalore, Karnataka, India</addr-line>
.</aff>
<aff id="aff3">
<label>3</label>
Tutor, Department of Pathology,
<institution>Sapthagiri Medical College and Hospital</institution>
,
<addr-line>Bangalore, Karnataka, India</addr-line>
.</aff>
<aff id="aff4">
<label>4</label>
Head of the Department, Department of Pathology,
<institution>Sapthagiri Medical College and Hospital</institution>
,
<addr-line>Bangalore, Karnataka, India</addr-line>
.</aff>
<author-notes>
<corresp id="cor1">NAME, ADDRESS, E-MAIL ID OF THE CORRESPONDING AUTHOR: Dr. Aparna Narasimha, No.22, Moyenvilla, Moyenville Road, Langford Town, Bangalore-560025, Karnataka, India. E-mail:
<email>Sonrichie14@gmail.com</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub">
<month>9</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="epub">
<day>01</day>
<month>9</month>
<year>2016</year>
</pub-date>
<volume>10</volume>
<issue>9</issue>
<fpage>ED08</fpage>
<lpage>ED09</lpage>
<history>
<date date-type="received">
<day>15</day>
<month>2</month>
<year>2016</year>
</date>
<date date-type="rev-request">
<day>24</day>
<month>5</month>
<year>2016</year>
</date>
<date date-type="accepted">
<day>04</day>
<month>7</month>
<year>2016</year>
</date>
</history>
<permissions>
<copyright-statement>© 2016 Journal of Clinical and Diagnostic Research</copyright-statement>
<copyright-year>2016</copyright-year>
</permissions>
<abstract>
<p>Lymphoedema can be classified into primary and secondary. Primary lymphoedema arise in patients where the cause is not known. Secondary lymphoedema are those in which the lymph system has been damaged by some well recognised pathological process, such as extensive malignancy, filariasis, radiation etc. The changes may occur either in the lymph node, or in lymph vessels or both. The clinical evolution and the prognosis of the oedema in the limb involved will depend on the extension and evolution of these lesions. The degree of fibrosis and its distribution in lymph node play an important role on the prognosis, clinical course and treatment of the patient. Hence pathologist should be aware of the microscopic distribution and patterns of lymph node fibrosis in primary lymphoedema. We hereby report two cases- a 50-year-old male diabetic patient and a 35-year-old male patient presenting with varicose veins, lymphoedema showing lymph node fibrosis.</p>
</abstract>
<kwd-group>
<kwd>Lymphodema</kwd>
<kwd>Lymph node fibrosis</kwd>
<kwd>Varicose veins</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

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