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<fileDesc>
<titleStmt>
<title xml:lang="en">
<italic>Wuchereria bancrofti</italic>
: Unusual Presentation as Pancytopenia</title>
<author>
<name sortKey="Jain, Mili" sort="Jain, Mili" uniqKey="Jain M" first="Mili" last="Jain">Mili Jain</name>
<affiliation>
<nlm:aff id="aff1"> Assistant Professor, Department of Pathology,
<institution>King George’s Medical University</institution>
,
<addr-line>Lucknow, UP, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Shukla, Ayush" sort="Shukla, Ayush" uniqKey="Shukla A" first="Ayush" last="Shukla">Ayush Shukla</name>
<affiliation>
<nlm:aff id="aff2"> Senior Resident, Department of Clinical Hematology,
<institution>King George’s Medical University</institution>
,
<addr-line>Lucknow, UP, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Kumar, Ashutosh" sort="Kumar, Ashutosh" uniqKey="Kumar A" first="Ashutosh" last="Kumar">Ashutosh Kumar</name>
<affiliation>
<nlm:aff id="aff3"> Professor, Department of Pathology,
<institution>King George’s Medical University</institution>
,
<addr-line>Lucknow, UP, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Kushwaha, Rashmi" sort="Kushwaha, Rashmi" uniqKey="Kushwaha R" first="Rashmi" last="Kushwaha">Rashmi Kushwaha</name>
<affiliation>
<nlm:aff id="aff4"> Associate Professor, Department of Pathology,
<institution>King George’s Medical University</institution>
,
<addr-line>Lucknow, UP, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Singh, Uma Shankar" sort="Singh, Uma Shankar" uniqKey="Singh U" first="Uma Shankar" last="Singh">Uma Shankar Singh</name>
<affiliation>
<nlm:aff id="aff5"> Professor, Department of Pathology,
<institution>King George’s Medical University</institution>
,
<addr-line>Lucknow, UP, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">PMC</idno>
<idno type="pmid">27630856</idno>
<idno type="pmc">5020304</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020304</idno>
<idno type="RBID">PMC:5020304</idno>
<idno type="doi">10.7860/JCDR/2016/18960.8084</idno>
<date when="2016">2016</date>
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<title xml:lang="en" level="a" type="main">
<italic>Wuchereria bancrofti</italic>
: Unusual Presentation as Pancytopenia</title>
<author>
<name sortKey="Jain, Mili" sort="Jain, Mili" uniqKey="Jain M" first="Mili" last="Jain">Mili Jain</name>
<affiliation>
<nlm:aff id="aff1"> Assistant Professor, Department of Pathology,
<institution>King George’s Medical University</institution>
,
<addr-line>Lucknow, UP, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Shukla, Ayush" sort="Shukla, Ayush" uniqKey="Shukla A" first="Ayush" last="Shukla">Ayush Shukla</name>
<affiliation>
<nlm:aff id="aff2"> Senior Resident, Department of Clinical Hematology,
<institution>King George’s Medical University</institution>
,
<addr-line>Lucknow, UP, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Kumar, Ashutosh" sort="Kumar, Ashutosh" uniqKey="Kumar A" first="Ashutosh" last="Kumar">Ashutosh Kumar</name>
<affiliation>
<nlm:aff id="aff3"> Professor, Department of Pathology,
<institution>King George’s Medical University</institution>
,
<addr-line>Lucknow, UP, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Kushwaha, Rashmi" sort="Kushwaha, Rashmi" uniqKey="Kushwaha R" first="Rashmi" last="Kushwaha">Rashmi Kushwaha</name>
<affiliation>
<nlm:aff id="aff4"> Associate Professor, Department of Pathology,
<institution>King George’s Medical University</institution>
,
<addr-line>Lucknow, UP, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Singh, Uma Shankar" sort="Singh, Uma Shankar" uniqKey="Singh U" first="Uma Shankar" last="Singh">Uma Shankar Singh</name>
<affiliation>
<nlm:aff id="aff5"> Professor, Department of Pathology,
<institution>King George’s Medical University</institution>
,
<addr-line>Lucknow, UP, India</addr-line>
.</nlm:aff>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Journal of Clinical and Diagnostic Research : JCDR</title>
<idno type="ISSN">2249-782X</idno>
<idno type="eISSN">0973-709X</idno>
<imprint>
<date when="2016">2016</date>
</imprint>
</series>
</biblStruct>
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<textClass></textClass>
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</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<p>
<italic>Wuchereria bancrofti</italic>
is an endemic filarial nematode spread by a mosquito vector. The clinical manifestations vary from asymptomatic microfilaremeia to lymhoedema. We report two cases of microfilaria of
<italic>Wuchereria bancrofti</italic>
in bone marrow presenting as peripheral pancytopenia. The patient did not have any classical features of lymphoedema or elephantiasis. The diagnostic demonstration of microfilaria with unusual presentations has been done in cytology specimens from various sites. Microfilaria infection in association with peripheral blood pancytopenia has been rarely reported. An aetiopathological co-relation of these haematological manifestations of microfilaria needs further investigation.</p>
</div>
</front>
</TEI>
<pmc article-type="case-report">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">J Clin Diagn Res</journal-id>
<journal-id journal-id-type="iso-abbrev">J Clin Diagn Res</journal-id>
<journal-id journal-id-type="hwp">Journal of Clinical and Diagnostic Research</journal-id>
<journal-id journal-id-type="publisher-id">JCDR</journal-id>
<journal-title-group>
<journal-title>Journal of Clinical and Diagnostic Research : JCDR</journal-title>
</journal-title-group>
<issn pub-type="ppub">2249-782X</issn>
<issn pub-type="epub">0973-709X</issn>
<publisher>
<publisher-name>JCDR Research and Publications (P) Limited</publisher-name>
<publisher-loc>Delhi, India</publisher-loc>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">27630856</article-id>
<article-id pub-id-type="pmc">5020304</article-id>
<article-id pub-id-type="doi">10.7860/JCDR/2016/18960.8084</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Pathology Section</subject>
<subj-group subj-group-type="heading">
<subject>Case Report</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>
<italic>Wuchereria bancrofti</italic>
: Unusual Presentation as Pancytopenia</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Jain</surname>
<given-names>Mili</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
<xref ref-type="corresp" rid="cor1"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Shukla</surname>
<given-names>Ayush</given-names>
</name>
<xref ref-type="aff" rid="aff2">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Kumar</surname>
<given-names>Ashutosh</given-names>
</name>
<xref ref-type="aff" rid="aff3">3</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Kushwaha</surname>
<given-names>Rashmi</given-names>
</name>
<xref ref-type="aff" rid="aff4">4</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Singh</surname>
<given-names>Uma Shankar</given-names>
</name>
<xref ref-type="aff" rid="aff5">5</xref>
</contrib>
</contrib-group>
<aff id="aff1">
<label>1</label>
Assistant Professor, Department of Pathology,
<institution>King George’s Medical University</institution>
,
<addr-line>Lucknow, UP, India</addr-line>
.</aff>
<aff id="aff2">
<label>2</label>
Senior Resident, Department of Clinical Hematology,
<institution>King George’s Medical University</institution>
,
<addr-line>Lucknow, UP, India</addr-line>
.</aff>
<aff id="aff3">
<label>3</label>
Professor, Department of Pathology,
<institution>King George’s Medical University</institution>
,
<addr-line>Lucknow, UP, India</addr-line>
.</aff>
<aff id="aff4">
<label>4</label>
Associate Professor, Department of Pathology,
<institution>King George’s Medical University</institution>
,
<addr-line>Lucknow, UP, India</addr-line>
.</aff>
<aff id="aff5">
<label>5</label>
Professor, Department of Pathology,
<institution>King George’s Medical University</institution>
,
<addr-line>Lucknow, UP, India</addr-line>
.</aff>
<author-notes>
<corresp id="cor1">NAME, ADDRESS, E-MAIL ID OF THE CORRESPONDING AUTHOR: Dr. Mili Jain, Assistant Professor, Department of Pathology, King George’s Medical University, Lucknow, UP-226003, India. E-mail:
<email>milijain786@gmail.com</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub">
<month>7</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="epub">
<day>01</day>
<month>7</month>
<year>2016</year>
</pub-date>
<volume>10</volume>
<issue>7</issue>
<fpage>ED05</fpage>
<lpage>ED06</lpage>
<history>
<date date-type="received">
<day>19</day>
<month>1</month>
<year>2016</year>
</date>
<date date-type="rev-request">
<day>16</day>
<month>3</month>
<year>2016</year>
</date>
<date date-type="accepted">
<day>25</day>
<month>4</month>
<year>2016</year>
</date>
</history>
<permissions>
<copyright-statement>© 2016 Journal of Clinical and Diagnostic Research</copyright-statement>
<copyright-year>2016</copyright-year>
</permissions>
<abstract>
<p>
<italic>Wuchereria bancrofti</italic>
is an endemic filarial nematode spread by a mosquito vector. The clinical manifestations vary from asymptomatic microfilaremeia to lymhoedema. We report two cases of microfilaria of
<italic>Wuchereria bancrofti</italic>
in bone marrow presenting as peripheral pancytopenia. The patient did not have any classical features of lymphoedema or elephantiasis. The diagnostic demonstration of microfilaria with unusual presentations has been done in cytology specimens from various sites. Microfilaria infection in association with peripheral blood pancytopenia has been rarely reported. An aetiopathological co-relation of these haematological manifestations of microfilaria needs further investigation.</p>
</abstract>
<kwd-group>
<kwd>Bone marrow parasite</kwd>
<kwd>Maturation arrest</kwd>
<kwd>Microfilariae</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

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