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Lymphatic filariasis morbidity mapping: a comprehensive examination of lymphoedema burden in Chikwawa district, Malawi

Identifieur interne : 000953 ( PascalFrancis/Curation ); précédent : 000952; suivant : 000954

Lymphatic filariasis morbidity mapping: a comprehensive examination of lymphoedema burden in Chikwawa district, Malawi

Auteurs : Emma L. Smith [Royaume-Uni] ; Square Z. Mkwanda [Malawi] ; Sarah Mortindate [Royaume-Uni] ; Louise A. Kelly-Hope [Royaume-Uni] ; Michelle C. Stanton [Royaume-Uni]

Source :

RBID : Pascal:15-0002418

Descripteurs français

English descriptors

Abstract

Background: Managing lymphatic filariasis (LF) morbidity and reducing disability is one of the two primary goals of the Global Programme to Eliminate Lymphatic Filariasis. However, in order to achieve this, the geographical distribution of LF morbidity needs to be better estimated. Methods: All cases of lymphoedema within a single health centre catchment area (pop. 42 000) in the southern region of Malawi were examined. Maps of lymphoedema burden were produced and trends in patient demo-graphics, severity of lymphoedema (Dreyer staging) and health-seeking behaviour were explored. The number of lymphoedema cases was compared with records maintained by the Ministry of Health, Malawi. Results: A total of 69 lymphoedema cases were identified (32 per 10 000 population), of which 48 (70%) were female and 21 (30%) mate. The majority of cases (51/69) had Dreyer stage 2-3, and almost all (65/69) had experienced acute attacks as a result of their lymphoedema. This burden was much greater than that estimated by Ministry of Health (33 cases). Conclusions: Current case detection methods underestimate the burden of lymphoedema in Malawi. There is a continued need to develop new LF morbidity identification and surveillance approaches to ensure that future morbidity management strategies are effectively targeted.
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A11 01  1    @1 SMITH (Emma L.)
A11 02  1    @1 MKWANDA (Square Z.)
A11 03  1    @1 MORTINDATE (Sarah)
A11 04  1    @1 KELLY-HOPE (Louise A.)
A11 05  1    @1 STANTON (Michelle C.)
A14 01      @1 Centre for Neglected Tropical Diseases, Department of Parasitology, Liverpool School of Tropical Medicine @2 Liverpool, L3 5QA @3 GBR @Z 1 aut. @Z 3 aut. @Z 4 aut. @Z 5 aut.
A14 02      @1 National Lymphatic Filariasis Elimination Programme, Ministry of Health @2 Lilongwe @3 MWI @Z 2 aut.
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C01 01    ENG  @0 Background: Managing lymphatic filariasis (LF) morbidity and reducing disability is one of the two primary goals of the Global Programme to Eliminate Lymphatic Filariasis. However, in order to achieve this, the geographical distribution of LF morbidity needs to be better estimated. Methods: All cases of lymphoedema within a single health centre catchment area (pop. 42 000) in the southern region of Malawi were examined. Maps of lymphoedema burden were produced and trends in patient demo-graphics, severity of lymphoedema (Dreyer staging) and health-seeking behaviour were explored. The number of lymphoedema cases was compared with records maintained by the Ministry of Health, Malawi. Results: A total of 69 lymphoedema cases were identified (32 per 10 000 population), of which 48 (70%) were female and 21 (30%) mate. The majority of cases (51/69) had Dreyer stage 2-3, and almost all (65/69) had experienced acute attacks as a result of their lymphoedema. This burden was much greater than that estimated by Ministry of Health (33 cases). Conclusions: Current case detection methods underestimate the burden of lymphoedema in Malawi. There is a continued need to develop new LF morbidity identification and surveillance approaches to ensure that future morbidity management strategies are effectively targeted.
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C07 01  X  ENG  @0 Nematode disease
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C07 02  X  FRE  @0 Helminthiase
C07 02  X  ENG  @0 Helminthiasis
C07 02  X  SPA  @0 Helmintiasis
C07 03  X  FRE  @0 Parasitose
C07 03  X  ENG  @0 Parasitosis
C07 03  X  SPA  @0 Parasitosis
C07 04  X  FRE  @0 Infection
C07 04  X  ENG  @0 Infection
C07 04  X  SPA  @0 Infección
C07 05  X  FRE  @0 Afrique @2 NG
C07 05  X  ENG  @0 Africa @2 NG
C07 05  X  SPA  @0 Africa @2 NG
C07 06  X  FRE  @0 Pathologie des vaisseaux lymphatiques @5 37
C07 06  X  ENG  @0 Lymphatic vessel disease @5 37
C07 06  X  SPA  @0 Linfático patología @5 37
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N21       @1 005
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<term>Cartography</term>
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<term>Morbidity</term>
<term>Prognosis</term>
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<term>Filariose lymphatique</term>
<term>Lymphoedème</term>
<term>Cartographie</term>
<term>Morbidité</term>
<term>Malawi</term>
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<term>Médecine tropicale</term>
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<div type="abstract" xml:lang="en">Background: Managing lymphatic filariasis (LF) morbidity and reducing disability is one of the two primary goals of the Global Programme to Eliminate Lymphatic Filariasis. However, in order to achieve this, the geographical distribution of LF morbidity needs to be better estimated. Methods: All cases of lymphoedema within a single health centre catchment area (pop. 42 000) in the southern region of Malawi were examined. Maps of lymphoedema burden were produced and trends in patient demo-graphics, severity of lymphoedema (Dreyer staging) and health-seeking behaviour were explored. The number of lymphoedema cases was compared with records maintained by the Ministry of Health, Malawi. Results: A total of 69 lymphoedema cases were identified (32 per 10 000 population), of which 48 (70%) were female and 21 (30%) mate. The majority of cases (51/69) had Dreyer stage 2-3, and almost all (65/69) had experienced acute attacks as a result of their lymphoedema. This burden was much greater than that estimated by Ministry of Health (33 cases). Conclusions: Current case detection methods underestimate the burden of lymphoedema in Malawi. There is a continued need to develop new LF morbidity identification and surveillance approaches to ensure that future morbidity management strategies are effectively targeted.</div>
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<s0>Background: Managing lymphatic filariasis (LF) morbidity and reducing disability is one of the two primary goals of the Global Programme to Eliminate Lymphatic Filariasis. However, in order to achieve this, the geographical distribution of LF morbidity needs to be better estimated. Methods: All cases of lymphoedema within a single health centre catchment area (pop. 42 000) in the southern region of Malawi were examined. Maps of lymphoedema burden were produced and trends in patient demo-graphics, severity of lymphoedema (Dreyer staging) and health-seeking behaviour were explored. The number of lymphoedema cases was compared with records maintained by the Ministry of Health, Malawi. Results: A total of 69 lymphoedema cases were identified (32 per 10 000 population), of which 48 (70%) were female and 21 (30%) mate. The majority of cases (51/69) had Dreyer stage 2-3, and almost all (65/69) had experienced acute attacks as a result of their lymphoedema. This burden was much greater than that estimated by Ministry of Health (33 cases). Conclusions: Current case detection methods underestimate the burden of lymphoedema in Malawi. There is a continued need to develop new LF morbidity identification and surveillance approaches to ensure that future morbidity management strategies are effectively targeted.</s0>
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<s0>Balance de extensión</s0>
<s5>09</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE">
<s0>Médecine tropicale</s0>
<s5>13</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG">
<s0>Tropical medicine</s0>
<s5>13</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA">
<s0>Medicina tropical</s0>
<s5>13</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE">
<s0>Pronostic</s0>
<s5>30</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG">
<s0>Prognosis</s0>
<s5>30</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA">
<s0>Pronóstico</s0>
<s5>30</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE">
<s0>Nématodose</s0>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>Nematode disease</s0>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>Nematodosis</s0>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Helminthiase</s0>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Helminthiasis</s0>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Helmintiasis</s0>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Parasitose</s0>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Parasitosis</s0>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Parasitosis</s0>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Infection</s0>
</fC07>
<fC07 i1="04" i2="X" l="ENG">
<s0>Infection</s0>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Infección</s0>
</fC07>
<fC07 i1="05" i2="X" l="FRE">
<s0>Afrique</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="05" i2="X" l="ENG">
<s0>Africa</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="05" i2="X" l="SPA">
<s0>Africa</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="06" i2="X" l="FRE">
<s0>Pathologie des vaisseaux lymphatiques</s0>
<s5>37</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG">
<s0>Lymphatic vessel disease</s0>
<s5>37</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA">
<s0>Linfático patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="07" i2="X" l="FRE">
<s0>Pathologie de l'appareil circulatoire</s0>
<s5>38</s5>
</fC07>
<fC07 i1="07" i2="X" l="ENG">
<s0>Cardiovascular disease</s0>
<s5>38</s5>
</fC07>
<fC07 i1="07" i2="X" l="SPA">
<s0>Aparato circulatorio patología</s0>
<s5>38</s5>
</fC07>
<fN21>
<s1>005</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
</record>

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