LymphedemaV1, PascalFrancis, Checkpoint, bibRecord, 000456

One-sided limb lymphedema in a liver transplant recipient receiving Sirolimus

Identifieur interne : 000456 ( PascalFrancis/Checkpoint ); précédent : 000455; suivant : 000457

One-sided limb lymphedema in a liver transplant recipient receiving Sirolimus

Auteurs : M. Van Onna [Belgique] ; A. Geerts [Belgique] ; H. Van Vlierberghe [Belgique] ; F. Berrevoet [Belgique] ; B. De Hemptinne [Belgique] ; R. Troisi [Belgique] ; I. Colle [Belgique]

Source :

Acta gastro-enterologica belgica [ 0001-5644 ] ; 2007.

RBID : Pascal:08-0121554

Descripteurs français

Pascal (Inist)
- Sirolimus, Membre, Lymphoedème, Foie, Homotransplantation, Oedème, Toxicité, Transplantation, Antibactérien, Antibiotique, Anticancéreux, Immunodépresseur, Traitement.
Wicri :
- topic : Antibiotique.

English descriptors

KwdEn :
- Antibacterial agent, Antibiotic, Antineoplastic agent, Edema, Homotransplantation, Immunosuppressive agent, Limb, Liver, Lymphedema, Sirolimus, Toxicity, Transplantation, Treatment.

Abstract

Sirolimus (SRL) is associated with many side effects including hypercholesterolemia, anaemia, impaired wound healing and abnormal liver function tests. Limb lymphedema has only been reported several times in renal transplant recipients. We present a case of lower limb lymphedema that occurred in a 59-year-old liver transplant recipient after being on a SRL regimen for seven months. Extensive diagnostic investigations could not reveal signs of infection, venous obstruction or malignancy. After discontinuation of SRL, the lymphedema gradually resolved during the next three months. The pathologic mechanism behind this phenomenon is unknown, but antiangiogenetic and antiproliferative properties of SRL have been hold responsible. Further studies are necessary to explain this rare side effect.

Affiliations:

Belgique

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Le document en format XML

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</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Pathologie des vaisseaux lymphatiques</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Lymphatic vessel disease</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Linfático patología</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Chirurgie</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Surgery</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Cirugía</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Greffe</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Graft</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Injerto</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Lactone</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Lactone</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Lactona</s0>
<s5>41</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE"><s0>Macrocycle</s0>
<s5>42</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG"><s0>Macrocycle</s0>
<s5>42</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA"><s0>Macrociclo</s0>
<s5>42</s5>
</fC07>
<fC07 i1="07" i2="X" l="FRE"><s0>Macrolide</s0>
<s5>43</s5>
</fC07>
<fC07 i1="07" i2="X" l="ENG"><s0>Macrolide</s0>
<s5>43</s5>
</fC07>
<fC07 i1="07" i2="X" l="SPA"><s0>Macrólido</s0>
<s5>43</s5>
</fC07>
<fC07 i1="08" i2="X" l="FRE"><s0>Inhibiteur synthèse protéique</s0>
<s5>44</s5>
</fC07>
<fC07 i1="08" i2="X" l="ENG"><s0>Protein synthesis inhibitor</s0>
<s5>44</s5>
</fC07>
<fC07 i1="08" i2="X" l="SPA"><s0>Inhibidor síntesis proteica</s0>
<s5>44</s5>
</fC07>
<fC07 i1="09" i2="X" l="FRE"><s0>Inhibiteur mTOR</s0>
<s4>INC</s4>
<s5>86</s5>
</fC07>
<fN21><s1>070</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
<affiliations><list><country><li>Belgique</li>
</country>
</list>
<tree><country name="Belgique"><noRegion><name sortKey="Van Onna, M" sort="Van Onna, M" uniqKey="Van Onna M" first="M." last="Van Onna">M. Van Onna</name>
</noRegion>
<name sortKey="Berrevoet, F" sort="Berrevoet, F" uniqKey="Berrevoet F" first="F." last="Berrevoet">F. Berrevoet</name>
<name sortKey="Colle, I" sort="Colle, I" uniqKey="Colle I" first="I." last="Colle">I. Colle</name>
<name sortKey="De Hemptinne, B" sort="De Hemptinne, B" uniqKey="De Hemptinne B" first="B." last="De Hemptinne">B. De Hemptinne</name>
<name sortKey="Geerts, A" sort="Geerts, A" uniqKey="Geerts A" first="A." last="Geerts">A. Geerts</name>
<name sortKey="Troisi, R" sort="Troisi, R" uniqKey="Troisi R" first="R." last="Troisi">R. Troisi</name>
<name sortKey="Van Vlierberghe, H" sort="Van Vlierberghe, H" uniqKey="Van Vlierberghe H" first="H." last="Van Vlierberghe">H. Van Vlierberghe</name>
</country>
</tree>
</affiliations>
</record>

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   |texte=   One-sided limb lymphedema in a liver transplant recipient receiving Sirolimus
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This area was generated with Dilib version V0.6.31.
Data generation: Sat Nov 4 17:40:35 2017. Site generation: Tue Feb 13 16:42:16 2024

	Serveur d'exploration sur le lymphœdème
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Serveur d'exploration sur le lymphœdème

One-sided limb lymphedema in a liver transplant recipient receiving Sirolimus

One-sided limb lymphedema in a liver transplant recipient receiving Sirolimus

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