LymphedemaV1, PascalFrancis, Curation, bibRecord, 000549

One-sided limb lymphedema in a liver transplant recipient receiving Sirolimus

Identifieur interne : 000549 ( PascalFrancis/Curation ); précédent : 000548; suivant : 000550

One-sided limb lymphedema in a liver transplant recipient receiving Sirolimus

Auteurs : M. Van Onna [Belgique] ; A. Geerts [Belgique] ; H. Van Vlierberghe [Belgique] ; F. Berrevoet [Belgique] ; B. De Hemptinne [Belgique] ; R. Troisi [Belgique] ; I. Colle [Belgique]

Source :

Acta gastro-enterologica belgica [ 0001-5644 ] ; 2007.

RBID : Pascal:08-0121554

Descripteurs français

Pascal (Inist)
- Sirolimus, Membre, Lymphoedème, Foie, Homotransplantation, Oedème, Toxicité, Transplantation, Antibactérien, Antibiotique, Anticancéreux, Immunodépresseur, Traitement.
Wicri :
- topic : Antibiotique.

English descriptors

KwdEn :
- Antibacterial agent, Antibiotic, Antineoplastic agent, Edema, Homotransplantation, Immunosuppressive agent, Limb, Liver, Lymphedema, Sirolimus, Toxicity, Transplantation, Treatment.

Abstract

Sirolimus (SRL) is associated with many side effects including hypercholesterolemia, anaemia, impaired wound healing and abnormal liver function tests. Limb lymphedema has only been reported several times in renal transplant recipients. We present a case of lower limb lymphedema that occurred in a 59-year-old liver transplant recipient after being on a SRL regimen for seven months. Extensive diagnostic investigations could not reveal signs of infection, venous obstruction or malignancy. After discontinuation of SRL, the lymphedema gradually resolved during the next three months. The pathologic mechanism behind this phenomenon is unknown, but antiangiogenetic and antiproliferative properties of SRL have been hold responsible. Further studies are necessary to explain this rare side effect.

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A08	`01`	`1`	`ENG`	`@1 One-sided limb lymphedema in a liver transplant recipient receiving Sirolimus`
A11	`01`	`1`		`@1 VAN ONNA (M.)`
A11	`02`	`1`		`@1 GEERTS (A.)`
A11	`03`	`1`		`@1 VAN VLIERBERGHE (H.)`
A11	`04`	`1`		`@1 BERREVOET (F.)`
A11	`05`	`1`		`@1 DE HEMPTINNE (B.)`
A11	`06`	`1`		`@1 TROISI (R.)`
A11	`07`	`1`		`@1 COLLE (I.)`
A14	`01`			`@1 Department of Gastroenterology and Hepatology, Ghent University Hospital @3 BEL @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 7 aut.`
A14	`02`			`@1 Department of Hepatobiliary Surgery and Liver Transplantation, Ghent University Hospital @3 BEL @Z 4 aut. @Z 5 aut. @Z 6 aut.`
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C01	`01`		`ENG`	@0 Sirolimus (SRL) is associated with many side effects including hypercholesterolemia, anaemia, impaired wound healing and abnormal liver function tests. Limb lymphedema has only been reported several times in renal transplant recipients. We present a case of lower limb lymphedema that occurred in a 59-year-old liver transplant recipient after being on a SRL regimen for seven months. Extensive diagnostic investigations could not reveal signs of infection, venous obstruction or malignancy. After discontinuation of SRL, the lymphedema gradually resolved during the next three months. The pathologic mechanism behind this phenomenon is unknown, but antiangiogenetic and antiproliferative properties of SRL have been hold responsible. Further studies are necessary to explain this rare side effect.
C02	`01`	`X`		`@0 002B12B04`
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C03	`01`	`X`	`FRE`	`@0 Sirolimus @2 NK @2 FR @5 04`
C03	`01`	`X`	`ENG`	`@0 Sirolimus @2 NK @2 FR @5 04`
C03	`01`	`X`	`SPA`	`@0 Sirolimús @2 NK @2 FR @5 04`
C03	`02`	`X`	`FRE`	`@0 Membre @5 07`
C03	`02`	`X`	`ENG`	`@0 Limb @5 07`
C03	`02`	`X`	`SPA`	`@0 Miembro @5 07`
C03	`03`	`X`	`FRE`	`@0 Lymphoedème @5 08`
C03	`03`	`X`	`ENG`	`@0 Lymphedema @5 08`
C03	`03`	`X`	`SPA`	`@0 Linfedema @5 08`
C03	`04`	`X`	`FRE`	`@0 Foie @5 09`
C03	`04`	`X`	`ENG`	`@0 Liver @5 09`
C03	`04`	`X`	`SPA`	`@0 Hígado @5 09`
C03	`05`	`X`	`FRE`	`@0 Homotransplantation @5 13`
C03	`05`	`X`	`ENG`	`@0 Homotransplantation @5 13`
C03	`05`	`X`	`SPA`	`@0 Homotrasplante @5 13`
C03	`06`	`X`	`FRE`	`@0 Oedème @5 14`
C03	`06`	`X`	`ENG`	`@0 Edema @5 14`
C03	`06`	`X`	`SPA`	`@0 Edema @5 14`
C03	`07`	`X`	`FRE`	`@0 Toxicité @5 15`
C03	`07`	`X`	`ENG`	`@0 Toxicity @5 15`
C03	`07`	`X`	`SPA`	`@0 Toxicidad @5 15`
C03	`08`	`X`	`FRE`	`@0 Transplantation @5 16`
C03	`08`	`X`	`ENG`	`@0 Transplantation @5 16`
C03	`08`	`X`	`SPA`	`@0 Trasplantación @5 16`
C03	`09`	`X`	`FRE`	`@0 Antibactérien @5 30`
C03	`09`	`X`	`ENG`	`@0 Antibacterial agent @5 30`
C03	`09`	`X`	`SPA`	`@0 Antibacteriano @5 30`
C03	`10`	`X`	`FRE`	`@0 Antibiotique @5 31`
C03	`10`	`X`	`ENG`	`@0 Antibiotic @5 31`
C03	`10`	`X`	`SPA`	`@0 Antibiótico @5 31`
C03	`11`	`X`	`FRE`	`@0 Anticancéreux @5 32`
C03	`11`	`X`	`ENG`	`@0 Antineoplastic agent @5 32`
C03	`11`	`X`	`SPA`	`@0 Anticanceroso @5 32`
C03	`12`	`X`	`FRE`	`@0 Immunodépresseur @5 33`
C03	`12`	`X`	`ENG`	`@0 Immunosuppressive agent @5 33`
C03	`12`	`X`	`SPA`	`@0 Inmunodepresor @5 33`
C03	`13`	`X`	`FRE`	`@0 Traitement @5 34`
C03	`13`	`X`	`ENG`	`@0 Treatment @5 34`
C03	`13`	`X`	`SPA`	`@0 Tratamiento @5 34`
C07	`01`	`X`	`FRE`	`@0 Pathologie de l'appareil circulatoire @5 37`
C07	`01`	`X`	`ENG`	`@0 Cardiovascular disease @5 37`
C07	`01`	`X`	`SPA`	`@0 Aparato circulatorio patología @5 37`
C07	`02`	`X`	`FRE`	`@0 Pathologie des vaisseaux lymphatiques @5 38`
C07	`02`	`X`	`ENG`	`@0 Lymphatic vessel disease @5 38`
C07	`02`	`X`	`SPA`	`@0 Linfático patología @5 38`
C07	`03`	`X`	`FRE`	`@0 Chirurgie @5 39`
C07	`03`	`X`	`ENG`	`@0 Surgery @5 39`
C07	`03`	`X`	`SPA`	`@0 Cirugía @5 39`
C07	`04`	`X`	`FRE`	`@0 Greffe @5 40`
C07	`04`	`X`	`ENG`	`@0 Graft @5 40`
C07	`04`	`X`	`SPA`	`@0 Injerto @5 40`
C07	`05`	`X`	`FRE`	`@0 Lactone @5 41`
C07	`05`	`X`	`ENG`	`@0 Lactone @5 41`
C07	`05`	`X`	`SPA`	`@0 Lactona @5 41`
C07	`06`	`X`	`FRE`	`@0 Macrocycle @5 42`
C07	`06`	`X`	`ENG`	`@0 Macrocycle @5 42`
C07	`06`	`X`	`SPA`	`@0 Macrociclo @5 42`
C07	`07`	`X`	`FRE`	`@0 Macrolide @5 43`
C07	`07`	`X`	`ENG`	`@0 Macrolide @5 43`
C07	`07`	`X`	`SPA`	`@0 Macrólido @5 43`
C07	`08`	`X`	`FRE`	`@0 Inhibiteur synthèse protéique @5 44`
C07	`08`	`X`	`ENG`	`@0 Protein synthesis inhibitor @5 44`
C07	`08`	`X`	`SPA`	`@0 Inhibidor síntesis proteica @5 44`
C07	`09`	`X`	`FRE`	`@0 Inhibiteur mTOR @4 INC @5 86`
N21				`@1 070`
N44	`01`			`@1 OTO`
N82				`@1 OTO`

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Pascal:08-0121554

Le document en format XML

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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">One-sided limb lymphedema in a liver transplant recipient receiving Sirolimus</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antibacterial agent</term>
<term>Antibiotic</term>
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<term>Edema</term>
<term>Homotransplantation</term>
<term>Immunosuppressive agent</term>
<term>Limb</term>
<term>Liver</term>
<term>Lymphedema</term>
<term>Sirolimus</term>
<term>Toxicity</term>
<term>Transplantation</term>
<term>Treatment</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Sirolimus</term>
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<term>Toxicité</term>
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<front><div type="abstract" xml:lang="en">Sirolimus (SRL) is associated with many side effects including hypercholesterolemia, anaemia, impaired wound healing and abnormal liver function tests. Limb lymphedema has only been reported several times in renal transplant recipients. We present a case of lower limb lymphedema that occurred in a 59-year-old liver transplant recipient after being on a SRL regimen for seven months. Extensive diagnostic investigations could not reveal signs of infection, venous obstruction or malignancy. After discontinuation of SRL, the lymphedema gradually resolved during the next three months. The pathologic mechanism behind this phenomenon is unknown, but antiangiogenetic and antiproliferative properties of SRL have been hold responsible. Further studies are necessary to explain this rare side effect.</div>
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<fC01 i1="01" l="ENG"><s0>Sirolimus (SRL) is associated with many side effects including hypercholesterolemia, anaemia, impaired wound healing and abnormal liver function tests. Limb lymphedema has only been reported several times in renal transplant recipients. We present a case of lower limb lymphedema that occurred in a 59-year-old liver transplant recipient after being on a SRL regimen for seven months. Extensive diagnostic investigations could not reveal signs of infection, venous obstruction or malignancy. After discontinuation of SRL, the lymphedema gradually resolved during the next three months. The pathologic mechanism behind this phenomenon is unknown, but antiangiogenetic and antiproliferative properties of SRL have been hold responsible. Further studies are necessary to explain this rare side effect.</s0>
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<fC02 i1="02" i2="X"><s0>002B02S02</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Sirolimus</s0>
<s2>NK</s2>
<s2>FR</s2>
<s5>04</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Sirolimus</s0>
<s2>NK</s2>
<s2>FR</s2>
<s5>04</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Sirolimús</s0>
<s2>NK</s2>
<s2>FR</s2>
<s5>04</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Membre</s0>
<s5>07</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Limb</s0>
<s5>07</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Miembro</s0>
<s5>07</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Lymphoedème</s0>
<s5>08</s5>
</fC03>
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<s5>08</s5>
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<fC03 i1="03" i2="X" l="SPA"><s0>Linfedema</s0>
<s5>08</s5>
</fC03>
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<s5>09</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Liver</s0>
<s5>09</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Hígado</s0>
<s5>09</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Homotransplantation</s0>
<s5>13</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Homotransplantation</s0>
<s5>13</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Homotrasplante</s0>
<s5>13</s5>
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<fC03 i1="06" i2="X" l="FRE"><s0>Oedème</s0>
<s5>14</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Edema</s0>
<s5>14</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Edema</s0>
<s5>14</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Toxicité</s0>
<s5>15</s5>
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<fC03 i1="07" i2="X" l="ENG"><s0>Toxicity</s0>
<s5>15</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Toxicidad</s0>
<s5>15</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE"><s0>Transplantation</s0>
<s5>16</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>Transplantation</s0>
<s5>16</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>Trasplantación</s0>
<s5>16</s5>
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<fC03 i1="09" i2="X" l="FRE"><s0>Antibactérien</s0>
<s5>30</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG"><s0>Antibacterial agent</s0>
<s5>30</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA"><s0>Antibacteriano</s0>
<s5>30</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE"><s0>Antibiotique</s0>
<s5>31</s5>
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<fC03 i1="10" i2="X" l="ENG"><s0>Antibiotic</s0>
<s5>31</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA"><s0>Antibiótico</s0>
<s5>31</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE"><s0>Anticancéreux</s0>
<s5>32</s5>
</fC03>
<fC03 i1="11" i2="X" l="ENG"><s0>Antineoplastic agent</s0>
<s5>32</s5>
</fC03>
<fC03 i1="11" i2="X" l="SPA"><s0>Anticanceroso</s0>
<s5>32</s5>
</fC03>
<fC03 i1="12" i2="X" l="FRE"><s0>Immunodépresseur</s0>
<s5>33</s5>
</fC03>
<fC03 i1="12" i2="X" l="ENG"><s0>Immunosuppressive agent</s0>
<s5>33</s5>
</fC03>
<fC03 i1="12" i2="X" l="SPA"><s0>Inmunodepresor</s0>
<s5>33</s5>
</fC03>
<fC03 i1="13" i2="X" l="FRE"><s0>Traitement</s0>
<s5>34</s5>
</fC03>
<fC03 i1="13" i2="X" l="ENG"><s0>Treatment</s0>
<s5>34</s5>
</fC03>
<fC03 i1="13" i2="X" l="SPA"><s0>Tratamiento</s0>
<s5>34</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Pathologie de l'appareil circulatoire</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Cardiovascular disease</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Aparato circulatorio patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Pathologie des vaisseaux lymphatiques</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Lymphatic vessel disease</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Linfático patología</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Chirurgie</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Surgery</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Cirugía</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Greffe</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Graft</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Injerto</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Lactone</s0>
<s5>41</s5>
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<fC07 i1="05" i2="X" l="ENG"><s0>Lactone</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Lactona</s0>
<s5>41</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE"><s0>Macrocycle</s0>
<s5>42</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG"><s0>Macrocycle</s0>
<s5>42</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA"><s0>Macrociclo</s0>
<s5>42</s5>
</fC07>
<fC07 i1="07" i2="X" l="FRE"><s0>Macrolide</s0>
<s5>43</s5>
</fC07>
<fC07 i1="07" i2="X" l="ENG"><s0>Macrolide</s0>
<s5>43</s5>
</fC07>
<fC07 i1="07" i2="X" l="SPA"><s0>Macrólido</s0>
<s5>43</s5>
</fC07>
<fC07 i1="08" i2="X" l="FRE"><s0>Inhibiteur synthèse protéique</s0>
<s5>44</s5>
</fC07>
<fC07 i1="08" i2="X" l="ENG"><s0>Protein synthesis inhibitor</s0>
<s5>44</s5>
</fC07>
<fC07 i1="08" i2="X" l="SPA"><s0>Inhibidor síntesis proteica</s0>
<s5>44</s5>
</fC07>
<fC07 i1="09" i2="X" l="FRE"><s0>Inhibiteur mTOR</s0>
<s4>INC</s4>
<s5>86</s5>
</fC07>
<fN21><s1>070</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
</record>

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   |wiki=    Wicri/Sante
   |area=    LymphedemaV1
   |flux=    PascalFrancis
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   |type=    RBID
   |clé=     Pascal:08-0121554
   |texte=   One-sided limb lymphedema in a liver transplant recipient receiving Sirolimus
}}

This area was generated with Dilib version V0.6.31.
Data generation: Sat Nov 4 17:40:35 2017. Site generation: Tue Feb 13 16:42:16 2024

	Serveur d'exploration sur le lymphœdème
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur le lymphœdème

One-sided limb lymphedema in a liver transplant recipient receiving Sirolimus

One-sided limb lymphedema in a liver transplant recipient receiving Sirolimus

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Descripteurs français

English descriptors

Abstract

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