Quantifying the physical and socio-economic burden of filarial lymphoedema in Chikwawa District, Malawi
Identifieur interne : 000009 ( PascalFrancis/Checkpoint ); précédent : 000008; suivant : 000010Quantifying the physical and socio-economic burden of filarial lymphoedema in Chikwawa District, Malawi
Auteurs : Sarah Martindate [Royaume-Uni] ; Square Z. Mkwanda [Malawi] ; Emma Smith [Royaume-Uni] ; David Molyneux [Royaume-Uni] ; Michelle C. Stanton [Royaume-Uni] ; Louise A. Kelly-Hope [Royaume-Uni]Source :
- Transactions of the Royal Society of Tropical Medicine and Hygiene [ 0035-9203 ] ; 2014.
Descripteurs français
- Pascal (Inist)
- Wicri :
- geographic : Malawi.
- topic : Analyse quantitative.
English descriptors
- KwdEn :
Abstract
Background: Lymphatic filariasis (LF) is a disfiguring parasitic disease and one of the leading causes of disability in the world. This study aimed to assess the severity of lymphoedema, the physical restrictions and socio-economic impact on affected individuals living in an endemic community in Malawi. Methods: In a single health centre catchment area, a follow-up survey was conducted to assess 69 lymphoedema cases, and the impact of their condition in eight different areas of their lives. Differences were examined by sex, age and severity of disease. The overall level of disability was quantified and the impact of acute dermato-lymphangioadenitis (ADLA) attacks was examined. Results: Lymphoedema cases were most affected by pain/discomfort and anxiety/depression, which also had an economic impact. Male and older (>60 years) individuals reported more problems. Higher disability levels based on a quantified score were significantly associated with decreased walking distance and working hours. ADLA significantly increased pain/discomfort and reduced cognition, and also affected the individuals' self-care, social participation and ability to work. Conclusions: Filarial lymphoedema causes significant hardship, particularly in relation to ADLAs, and the scale of the problem needs to be better defined with new specific tools so that the best support and care can be provided to those in greatest need.
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Mkwanda</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>National Lymphatic Filariasis Elimination Programme, Ministry of Health</s1><s2>Lilongwe</s2><s3>MWI</s3><sZ>2 aut.</sZ></inist:fA14><country>Malawi</country><wicri:noRegion>Lilongwe</wicri:noRegion></affiliation></author><author><name sortKey="Smith, Emma" sort="Smith, Emma" uniqKey="Smith E" first="Emma" last="Smith">Emma Smith</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Centre for Neglected Tropical Diseases, Department of Parasitology, Liverpool School of Tropical Medicine</s1><s3>GBR</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Centre for Neglected Tropical Diseases, Department of Parasitology, Liverpool School of Tropical Medicine</wicri:noRegion></affiliation></author><author><name sortKey="Molyneux, David" sort="Molyneux, David" uniqKey="Molyneux D" first="David" last="Molyneux">David Molyneux</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Centre for Neglected Tropical Diseases, Department of Parasitology, Liverpool School of Tropical Medicine</s1><s3>GBR</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Centre for Neglected Tropical Diseases, Department of Parasitology, Liverpool School of Tropical Medicine</wicri:noRegion></affiliation></author><author><name sortKey="Stanton, Michelle C" sort="Stanton, Michelle C" uniqKey="Stanton M" first="Michelle C." last="Stanton">Michelle C. Stanton</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Centre for Neglected Tropical Diseases, Department of Parasitology, Liverpool School of Tropical Medicine</s1><s3>GBR</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Centre for Neglected Tropical Diseases, Department of Parasitology, Liverpool School of Tropical Medicine</wicri:noRegion></affiliation></author><author><name sortKey="Kelly Hope, Louise A" sort="Kelly Hope, Louise A" uniqKey="Kelly Hope L" first="Louise A." last="Kelly-Hope">Louise A. Kelly-Hope</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Centre for Neglected Tropical Diseases, Department of Parasitology, Liverpool School of Tropical Medicine</s1><s3>GBR</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Centre for Neglected Tropical Diseases, Department of Parasitology, Liverpool School of Tropical Medicine</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">Transactions of the Royal Society of Tropical Medicine and Hygiene</title><title level="j" type="abbreviated">Trans. r. soc. trop. med. hyg.</title><idno type="ISSN">0035-9203</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Transactions of the Royal Society of Tropical Medicine and Hygiene</title><title level="j" type="abbreviated">Trans. r. soc. trop. med. hyg.</title><idno type="ISSN">0035-9203</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Lymphatic filariasis</term><term>Lymphedema</term><term>Malawi</term><term>Quantitative analysis</term><term>Socioeconomic study</term><term>Staging</term><term>Tropical medicine</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Lymphoedème</term><term>Filariose lymphatique</term><term>Analyse quantitative</term><term>Etude socioéconomique</term><term>Malawi</term><term>Bilan d'extension</term><term>Médecine tropicale</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Malawi</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Analyse quantitative</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Background: Lymphatic filariasis (LF) is a disfiguring parasitic disease and one of the leading causes of disability in the world. This study aimed to assess the severity of lymphoedema, the physical restrictions and socio-economic impact on affected individuals living in an endemic community in Malawi. Methods: In a single health centre catchment area, a follow-up survey was conducted to assess 69 lymphoedema cases, and the impact of their condition in eight different areas of their lives. Differences were examined by sex, age and severity of disease. The overall level of disability was quantified and the impact of acute dermato-lymphangioadenitis (ADLA) attacks was examined. Results: Lymphoedema cases were most affected by pain/discomfort and anxiety/depression, which also had an economic impact. Male and older (>60 years) individuals reported more problems. Higher disability levels based on a quantified score were significantly associated with decreased walking distance and working hours. ADLA significantly increased pain/discomfort and reduced cognition, and also affected the individuals' self-care, social participation and ability to work. Conclusions: Filarial lymphoedema causes significant hardship, particularly in relation to ADLAs, and the scale of the problem needs to be better defined with new specific tools so that the best support and care can be provided to those in greatest need.</div></front></TEI><inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0035-9203</s0></fA01><fA02 i1="01"><s0>TRSTAZ</s0></fA02><fA03 i2="1"><s0>Trans. r. soc. trop. med. hyg.</s0></fA03><fA05><s2>108</s2></fA05><fA06><s2>12</s2></fA06><fA08 i1="01" i2="1" l="ENG"><s1>Quantifying the physical and socio-economic burden of filarial lymphoedema in Chikwawa District, Malawi</s1></fA08><fA11 i1="01" i2="1"><s1>MARTINDATE (Sarah)</s1></fA11><fA11 i1="02" i2="1"><s1>MKWANDA (Square Z.)</s1></fA11><fA11 i1="03" i2="1"><s1>SMITH (Emma)</s1></fA11><fA11 i1="04" i2="1"><s1>MOLYNEUX (David)</s1></fA11><fA11 i1="05" i2="1"><s1>STANTON (Michelle C.)</s1></fA11><fA11 i1="06" i2="1"><s1>KELLY-HOPE (Louise A.)</s1></fA11><fA14 i1="01"><s1>Centre for Neglected Tropical Diseases, Department of Parasitology, Liverpool School of Tropical Medicine</s1><s3>GBR</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></fA14><fA14 i1="02"><s1>National Lymphatic Filariasis Elimination Programme, Ministry of Health</s1><s2>Lilongwe</s2><s3>MWI</s3><sZ>2 aut.</sZ></fA14><fA20><s1>759-767</s1></fA20><fA21><s1>2014</s1></fA21><fA23 i1="01"><s0>ENG</s0></fA23><fA43 i1="01"><s1>INIST</s1><s2>3084</s2><s5>354000502525360040</s5></fA43><fA44><s0>0000</s0><s1>© 2015 INIST-CNRS. All rights reserved.</s1></fA44><fA45><s0>39 ref.</s0></fA45><fA47 i1="01" i2="1"><s0>15-0002420</s0></fA47><fA60><s1>P</s1></fA60><fA61><s0>A</s0></fA61><fA64 i1="01" i2="1"><s0>Transactions of the Royal Society of Tropical Medicine and Hygiene</s0></fA64><fA66 i1="01"><s0>GBR</s0></fA66><fC01 i1="01" l="ENG"><s0>Background: Lymphatic filariasis (LF) is a disfiguring parasitic disease and one of the leading causes of disability in the world. This study aimed to assess the severity of lymphoedema, the physical restrictions and socio-economic impact on affected individuals living in an endemic community in Malawi. Methods: In a single health centre catchment area, a follow-up survey was conducted to assess 69 lymphoedema cases, and the impact of their condition in eight different areas of their lives. Differences were examined by sex, age and severity of disease. The overall level of disability was quantified and the impact of acute dermato-lymphangioadenitis (ADLA) attacks was examined. Results: Lymphoedema cases were most affected by pain/discomfort and anxiety/depression, which also had an economic impact. Male and older (>60 years) individuals reported more problems. Higher disability levels based on a quantified score were significantly associated with decreased walking distance and working hours. ADLA significantly increased pain/discomfort and reduced cognition, and also affected the individuals' self-care, social participation and ability to work. Conclusions: Filarial lymphoedema causes significant hardship, particularly in relation to ADLAs, and the scale of the problem needs to be better defined with new specific tools so that the best support and care can be provided to those in greatest need.</s0></fC01><fC02 i1="01" i2="X"><s0>002B01</s0></fC02><fC02 i1="02" i2="X"><s0>002B12B04</s0></fC02><fC02 i1="03" i2="X"><s0>002B05E03B4D</s0></fC02><fC03 i1="01" i2="X" l="FRE"><s0>Lymphoedème</s0><s5>01</s5></fC03><fC03 i1="01" i2="X" l="ENG"><s0>Lymphedema</s0><s5>01</s5></fC03><fC03 i1="01" i2="X" l="SPA"><s0>Linfedema</s0><s5>01</s5></fC03><fC03 i1="02" i2="X" l="FRE"><s0>Filariose lymphatique</s0><s5>02</s5></fC03><fC03 i1="02" i2="X" l="ENG"><s0>Lymphatic filariasis</s0><s5>02</s5></fC03><fC03 i1="02" i2="X" l="SPA"><s0>Filariasis linfática</s0><s5>02</s5></fC03><fC03 i1="03" i2="X" l="FRE"><s0>Analyse quantitative</s0><s5>07</s5></fC03><fC03 i1="03" i2="X" l="ENG"><s0>Quantitative analysis</s0><s5>07</s5></fC03><fC03 i1="03" i2="X" l="SPA"><s0>Análisis cuantitativo</s0><s5>07</s5></fC03><fC03 i1="04" i2="X" l="FRE"><s0>Etude socioéconomique</s0><s5>08</s5></fC03><fC03 i1="04" i2="X" l="ENG"><s0>Socioeconomic study</s0><s5>08</s5></fC03><fC03 i1="04" i2="X" l="SPA"><s0>Estudio socioeconómico</s0><s5>08</s5></fC03><fC03 i1="05" i2="X" l="FRE"><s0>Malawi</s0><s2>NG</s2><s5>09</s5></fC03><fC03 i1="05" i2="X" l="ENG"><s0>Malawi</s0><s2>NG</s2><s5>09</s5></fC03><fC03 i1="05" i2="X" l="SPA"><s0>Malawi</s0><s2>NG</s2><s5>09</s5></fC03><fC03 i1="06" i2="X" l="FRE"><s0>Bilan d'extension</s0><s5>13</s5></fC03><fC03 i1="06" i2="X" l="ENG"><s0>Staging</s0><s5>13</s5></fC03><fC03 i1="06" i2="X" l="SPA"><s0>Balance de extensión</s0><s5>13</s5></fC03><fC03 i1="07" i2="X" l="FRE"><s0>Médecine tropicale</s0><s5>14</s5></fC03><fC03 i1="07" i2="X" l="ENG"><s0>Tropical medicine</s0><s5>14</s5></fC03><fC03 i1="07" i2="X" l="SPA"><s0>Medicina tropical</s0><s5>14</s5></fC03><fC07 i1="01" i2="X" l="FRE"><s0>Nématodose</s0></fC07><fC07 i1="01" i2="X" l="ENG"><s0>Nematode disease</s0></fC07><fC07 i1="01" i2="X" l="SPA"><s0>Nematodosis</s0></fC07><fC07 i1="02" i2="X" l="FRE"><s0>Helminthiase</s0></fC07><fC07 i1="02" i2="X" l="ENG"><s0>Helminthiasis</s0></fC07><fC07 i1="02" i2="X" l="SPA"><s0>Helmintiasis</s0></fC07><fC07 i1="03" i2="X" l="FRE"><s0>Parasitose</s0></fC07><fC07 i1="03" i2="X" l="ENG"><s0>Parasitosis</s0></fC07><fC07 i1="03" i2="X" l="SPA"><s0>Parasitosis</s0></fC07><fC07 i1="04" i2="X" l="FRE"><s0>Infection</s0></fC07><fC07 i1="04" i2="X" l="ENG"><s0>Infection</s0></fC07><fC07 i1="04" i2="X" l="SPA"><s0>Infección</s0></fC07><fC07 i1="05" i2="X" l="FRE"><s0>Afrique</s0><s2>NG</s2></fC07><fC07 i1="05" i2="X" l="ENG"><s0>Africa</s0><s2>NG</s2></fC07><fC07 i1="05" i2="X" l="SPA"><s0>Africa</s0><s2>NG</s2></fC07><fC07 i1="06" i2="X" l="FRE"><s0>Pathologie de l'appareil circulatoire</s0><s5>37</s5></fC07><fC07 i1="06" i2="X" l="ENG"><s0>Cardiovascular disease</s0><s5>37</s5></fC07><fC07 i1="06" i2="X" l="SPA"><s0>Aparato circulatorio patología</s0><s5>37</s5></fC07><fC07 i1="07" i2="X" l="FRE"><s0>Pathologie des vaisseaux lymphatiques</s0><s5>38</s5></fC07><fC07 i1="07" i2="X" l="ENG"><s0>Lymphatic vessel disease</s0><s5>38</s5></fC07><fC07 i1="07" i2="X" l="SPA"><s0>Linfático patología</s0><s5>38</s5></fC07><fN21><s1>005</s1></fN21><fN44 i1="01"><s1>OTO</s1></fN44><fN82><s1>OTO</s1></fN82></pA></standard></inist><affiliations><list><country><li>Malawi</li><li>Royaume-Uni</li></country></list><tree><country name="Royaume-Uni"><noRegion><name sortKey="Martindate, Sarah" sort="Martindate, Sarah" uniqKey="Martindate S" first="Sarah" last="Martindate">Sarah Martindate</name></noRegion><name sortKey="Kelly Hope, Louise A" sort="Kelly Hope, Louise A" uniqKey="Kelly Hope L" first="Louise A." last="Kelly-Hope">Louise A. Kelly-Hope</name><name sortKey="Molyneux, David" sort="Molyneux, David" uniqKey="Molyneux D" first="David" last="Molyneux">David Molyneux</name><name sortKey="Smith, Emma" sort="Smith, Emma" uniqKey="Smith E" first="Emma" last="Smith">Emma Smith</name><name sortKey="Stanton, Michelle C" sort="Stanton, Michelle C" uniqKey="Stanton M" first="Michelle C." last="Stanton">Michelle C. Stanton</name></country><country name="Malawi"><noRegion><name sortKey="Mkwanda, Square Z" sort="Mkwanda, Square Z" uniqKey="Mkwanda S" first="Square Z." last="Mkwanda">Square Z. Mkwanda</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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