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Radical Hysterectomy Plus Concurrent Chemoradiation/Radiation Therapy Is Negatively Associated With Return to Work in Patients With Cervical Cancer.

Identifieur interne : 008839 ( Ncbi/Merge ); précédent : 008838; suivant : 008840

Radical Hysterectomy Plus Concurrent Chemoradiation/Radiation Therapy Is Negatively Associated With Return to Work in Patients With Cervical Cancer.

Auteurs : Keiichiro Nakamura [Japon] ; Hisashi Masuyama ; Naoyuki Ida ; Tomoko Haruma ; Tomoyuki Kusumoto ; Noriko Seki ; Yuji Hiramatsu

Source :

RBID : pubmed:27668396

Abstract

Cervical cancer is one of the most common malignant diseases in working-age women. This study investigated the influence of adverse effects of various treatment modalities on return to work in women with cervical cancer.

DOI: 10.1097/IGC.0000000000000840
PubMed: 27668396

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pubmed:27668396

Le document en format XML

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<title xml:lang="en">Radical Hysterectomy Plus Concurrent Chemoradiation/Radiation Therapy Is Negatively Associated With Return to Work in Patients With Cervical Cancer.</title>
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<name sortKey="Nakamura, Keiichiro" sort="Nakamura, Keiichiro" uniqKey="Nakamura K" first="Keiichiro" last="Nakamura">Keiichiro Nakamura</name>
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<nlm:affiliation>Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558</wicri:regionArea>
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<name sortKey="Masuyama, Hisashi" sort="Masuyama, Hisashi" uniqKey="Masuyama H" first="Hisashi" last="Masuyama">Hisashi Masuyama</name>
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<name sortKey="Ida, Naoyuki" sort="Ida, Naoyuki" uniqKey="Ida N" first="Naoyuki" last="Ida">Naoyuki Ida</name>
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<name sortKey="Haruma, Tomoko" sort="Haruma, Tomoko" uniqKey="Haruma T" first="Tomoko" last="Haruma">Tomoko Haruma</name>
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<name sortKey="Kusumoto, Tomoyuki" sort="Kusumoto, Tomoyuki" uniqKey="Kusumoto T" first="Tomoyuki" last="Kusumoto">Tomoyuki Kusumoto</name>
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<name sortKey="Seki, Noriko" sort="Seki, Noriko" uniqKey="Seki N" first="Noriko" last="Seki">Noriko Seki</name>
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<name sortKey="Hiramatsu, Yuji" sort="Hiramatsu, Yuji" uniqKey="Hiramatsu Y" first="Yuji" last="Hiramatsu">Yuji Hiramatsu</name>
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<name sortKey="Nakamura, Keiichiro" sort="Nakamura, Keiichiro" uniqKey="Nakamura K" first="Keiichiro" last="Nakamura">Keiichiro Nakamura</name>
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<name sortKey="Masuyama, Hisashi" sort="Masuyama, Hisashi" uniqKey="Masuyama H" first="Hisashi" last="Masuyama">Hisashi Masuyama</name>
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<name sortKey="Ida, Naoyuki" sort="Ida, Naoyuki" uniqKey="Ida N" first="Naoyuki" last="Ida">Naoyuki Ida</name>
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<name sortKey="Haruma, Tomoko" sort="Haruma, Tomoko" uniqKey="Haruma T" first="Tomoko" last="Haruma">Tomoko Haruma</name>
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<name sortKey="Kusumoto, Tomoyuki" sort="Kusumoto, Tomoyuki" uniqKey="Kusumoto T" first="Tomoyuki" last="Kusumoto">Tomoyuki Kusumoto</name>
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<name sortKey="Seki, Noriko" sort="Seki, Noriko" uniqKey="Seki N" first="Noriko" last="Seki">Noriko Seki</name>
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<name sortKey="Hiramatsu, Yuji" sort="Hiramatsu, Yuji" uniqKey="Hiramatsu Y" first="Yuji" last="Hiramatsu">Yuji Hiramatsu</name>
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<title level="j">International journal of gynecological cancer : official journal of the International Gynecological Cancer Society</title>
<idno type="eISSN">1525-1438</idno>
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<div type="abstract" xml:lang="en">Cervical cancer is one of the most common malignant diseases in working-age women. This study investigated the influence of adverse effects of various treatment modalities on return to work in women with cervical cancer.</div>
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<Month>09</Month>
<Day>26</Day>
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<Year>2016</Year>
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<ISSN IssnType="Electronic">1525-1438</ISSN>
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<Volume>27</Volume>
<Issue>1</Issue>
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<Year>2017</Year>
<Month>Jan</Month>
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<Title>International journal of gynecological cancer : official journal of the International Gynecological Cancer Society</Title>
<ISOAbbreviation>Int. J. Gynecol. Cancer</ISOAbbreviation>
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<ArticleTitle>Radical Hysterectomy Plus Concurrent Chemoradiation/Radiation Therapy Is Negatively Associated With Return to Work in Patients With Cervical Cancer.</ArticleTitle>
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<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">Cervical cancer is one of the most common malignant diseases in working-age women. This study investigated the influence of adverse effects of various treatment modalities on return to work in women with cervical cancer.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Questionnaires and clinical data from medical records of 97 patients with early stage (stages I and II) cervical cancer were collected and assessed by treatment received. The following treatment groups were analyzed for correlations between time to return to work and various adverse effects: radical hysterectomy (RH) alone, RH group (n = 29); concurrent chemoradiation therapy (CCRT)/radiation therapy (RT) alone, CCRT/RT group (n = 21); and RH + CCRT/RT group (n = 47). The χ test was used to determine the significance of the correlations.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The mean age at the time of diagnosis was 43.0 years and the average interval since treatment was 4.5 years. The RH + CCRT/RT group was the most strongly negatively associated with return to work in employed patients who had undergone CCRT/RT group of cervical cancer (P = 0.012). There was a significant association between failure to return to work and lower extremity lymphedema (P = 0.049). A more than-6-month interval between treatment and return to work and reduced personal income occurred in a significantly higher percentage of patients in the RH + CCRT group than in the CCRT/RT group (P = 0.034 and P = 0.034).</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Of the treatments assessed, RH + CCRT/RT has the greatest negative effect on return to work in women with cervical cancer.</AbstractText>
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