Retroperitoneal amyloidosis as the presenting manifestation of Waldenstrom's macroglobulinaemia
Identifieur interne : 005858 ( Ncbi/Merge ); précédent : 005857; suivant : 005859Retroperitoneal amyloidosis as the presenting manifestation of Waldenstrom's macroglobulinaemia
Auteurs : Domingo Franco-Palacios [États-Unis] ; Maher Tama [États-Unis] ; Suprotim Samaddar [États-Unis] ; Jay Yang [États-Unis]Source :
- BMJ Case Reports [ 1757-790X ] ; 2013.
Abstract
Retroperitoneal amyloidosis has been described in a few case reports and is typically a secondary manifestation of inflammation or malignancy. We present the case of a 69-year-old man who presented with a large pleural effusion and an incidental retroperitoneal mass in the CT imaging. Further investigation confirmed the diagnosis of amyloid amyloidosis involving the retroperitoneum as well as a concurrent Waldenstrom's macroglobulinaemia. Chemotherapy consistent of drugs active against both the lymphoid and plasma cell components of the disease is the proposed therapy for Waldenstrom's macroglobulinaemia in those patients amenable to receive chemotherapy and can make a difference in the survival.
Url:
DOI: 10.1136/bcr-2013-009329
PubMed: 23616327
PubMed Central: 3645597
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PMC:3645597Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>Retroperitoneal amyloidosis has been described in a few case reports and is typically a secondary manifestation of inflammation or malignancy. We present the case of a 69-year-old man who presented with a large pleural effusion and an incidental retroperitoneal mass in the CT imaging. Further investigation confirmed the diagnosis of amyloid amyloidosis involving the retroperitoneum as well as a concurrent Waldenstrom's macroglobulinaemia. Chemotherapy consistent of drugs active against both the lymphoid and plasma cell components of the disease is the proposed therapy for Waldenstrom's macroglobulinaemia in those patients amenable to receive chemotherapy and can make a difference in the survival.</p>
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<abstract><p>Retroperitoneal amyloidosis has been described in a few case reports and is typically a secondary manifestation of inflammation or malignancy. We present the case of a 69-year-old man who presented with a large pleural effusion and an incidental retroperitoneal mass in the CT imaging. Further investigation confirmed the diagnosis of amyloid amyloidosis involving the retroperitoneum as well as a concurrent Waldenstrom's macroglobulinaemia. Chemotherapy consistent of drugs active against both the lymphoid and plasma cell components of the disease is the proposed therapy for Waldenstrom's macroglobulinaemia in those patients amenable to receive chemotherapy and can make a difference in the survival.</p>
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