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Management of stage IV rectal cancer: Palliative options

Identifieur interne : 004202 ( Ncbi/Merge ); précédent : 004201; suivant : 004203

Management of stage IV rectal cancer: Palliative options

Auteurs : Sean M. Ronnekleiv-Kelly ; Gregory D. Kennedy

Source :

RBID : PMC:3051134

Abstract

Approximately 30% of patients with rectal cancer present with metastatic disease. Many of these patients have symptoms of bleeding or obstruction. Several treatment options are available to deal with the various complications that may afflict these patients. Endorectal stenting, laser ablation, and operative resection are a few of the options available to the patient with a malignant large bowel obstruction. A thorough understanding of treatment options will ensure the patient is offered the most effective therapy with the least amount of associated morbidity. In this review, we describe various options for palliation of symptoms in patients with metastatic rectal cancer. Additionally, we briefly discuss treatment for asymptomatic patients with metastatic disease.


Url:
DOI: 10.3748/wjg.v17.i7.835
PubMed: 21412493
PubMed Central: 3051134

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PMC:3051134

Le document en format XML

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<p>Approximately 30% of patients with rectal cancer present with metastatic disease. Many of these patients have symptoms of bleeding or obstruction. Several treatment options are available to deal with the various complications that may afflict these patients. Endorectal stenting, laser ablation, and operative resection are a few of the options available to the patient with a malignant large bowel obstruction. A thorough understanding of treatment options will ensure the patient is offered the most effective therapy with the least amount of associated morbidity. In this review, we describe various options for palliation of symptoms in patients with metastatic rectal cancer. Additionally, we briefly discuss treatment for asymptomatic patients with metastatic disease.</p>
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<aff>Sean M Ronnekleiv-Kelly, Gregory D Kennedy, Department of Surgery, Section of Colon and Rectal Surgery, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, G4/701A CSC, Madison, WI 53792, United States</aff>
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<p>Author contributions: Ronnekleiv-Kelly SM and Kennedy GD wrote the manuscript.</p>
<p>Correspondence to: Gregory D Kennedy, MD, PhD, Department of Surgery, Section of Colon and Rectal Surgery, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, G4/701A CSC, Madison, WI 53792, United States.
<email>kennedyg@surgery.wisc.edu</email>
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<p>Telephone: +1-608-2632521 Fax: +1-608-2637652</p>
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<abstract>
<p>Approximately 30% of patients with rectal cancer present with metastatic disease. Many of these patients have symptoms of bleeding or obstruction. Several treatment options are available to deal with the various complications that may afflict these patients. Endorectal stenting, laser ablation, and operative resection are a few of the options available to the patient with a malignant large bowel obstruction. A thorough understanding of treatment options will ensure the patient is offered the most effective therapy with the least amount of associated morbidity. In this review, we describe various options for palliation of symptoms in patients with metastatic rectal cancer. Additionally, we briefly discuss treatment for asymptomatic patients with metastatic disease.</p>
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