Management of stage IV rectal cancer: Palliative options
Identifieur interne : 002E67 ( Pmc/Checkpoint ); précédent : 002E66; suivant : 002E68Management of stage IV rectal cancer: Palliative options
Auteurs : Sean M. Ronnekleiv-Kelly ; Gregory D. KennedySource :
- World Journal of Gastroenterology : WJG [ 1007-9327 ] ; 2011.
Abstract
Approximately 30% of patients with rectal cancer present with metastatic disease. Many of these patients have symptoms of bleeding or obstruction. Several treatment options are available to deal with the various complications that may afflict these patients. Endorectal stenting, laser ablation, and operative resection are a few of the options available to the patient with a malignant large bowel obstruction. A thorough understanding of treatment options will ensure the patient is offered the most effective therapy with the least amount of associated morbidity. In this review, we describe various options for palliation of symptoms in patients with metastatic rectal cancer. Additionally, we briefly discuss treatment for asymptomatic patients with metastatic disease.
Url:
DOI: 10.3748/wjg.v17.i7.835
PubMed: 21412493
PubMed Central: 3051134
Affiliations:
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PMC:3051134Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>Approximately 30% of patients with rectal cancer present with metastatic disease. Many of these patients have symptoms of bleeding or obstruction. Several treatment options are available to deal with the various complications that may afflict these patients. Endorectal stenting, laser ablation, and operative resection are a few of the options available to the patient with a malignant large bowel obstruction. A thorough understanding of treatment options will ensure the patient is offered the most effective therapy with the least amount of associated morbidity. In this review, we describe various options for palliation of symptoms in patients with metastatic rectal cancer. Additionally, we briefly discuss treatment for asymptomatic patients with metastatic disease.</p>
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<pmc article-type="review-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">World J Gastroenterol</journal-id>
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<publisher><publisher-name>Baishideng Publishing Group Co., Limited</publisher-name>
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<contrib-group><contrib contrib-type="author"><name><surname>Ronnekleiv-Kelly</surname>
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<contrib contrib-type="author"><name><surname>Kennedy</surname>
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<aff>Sean M Ronnekleiv-Kelly, Gregory D Kennedy, Department of Surgery, Section of Colon and Rectal Surgery, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, G4/701A CSC, Madison, WI 53792, United States</aff>
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<author-notes><fn><p>Author contributions: Ronnekleiv-Kelly SM and Kennedy GD wrote the manuscript.</p>
<p>Correspondence to: Gregory D Kennedy, MD, PhD, Department of Surgery, Section of Colon and Rectal Surgery, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, G4/701A CSC, Madison, WI 53792, United States. <email>kennedyg@surgery.wisc.edu</email>
</p>
<p>Telephone: +1-608-2632521 Fax: +1-608-2637652</p>
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<volume>17</volume>
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<lpage>847</lpage>
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<year>2010</year>
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<permissions><copyright-statement>©2011 Baishideng Publishing Group Co., Limited. All rights reserved.</copyright-statement>
<copyright-year>2011</copyright-year>
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<abstract><p>Approximately 30% of patients with rectal cancer present with metastatic disease. Many of these patients have symptoms of bleeding or obstruction. Several treatment options are available to deal with the various complications that may afflict these patients. Endorectal stenting, laser ablation, and operative resection are a few of the options available to the patient with a malignant large bowel obstruction. A thorough understanding of treatment options will ensure the patient is offered the most effective therapy with the least amount of associated morbidity. In this review, we describe various options for palliation of symptoms in patients with metastatic rectal cancer. Additionally, we briefly discuss treatment for asymptomatic patients with metastatic disease.</p>
</abstract>
<kwd-group><kwd>Palliative therapy</kwd>
<kwd>Rectal cancer</kwd>
<kwd>Malignant bleeding</kwd>
<kwd>Malignant obstruction</kwd>
<kwd>Endorectal stenting</kwd>
<kwd>Laser ablation</kwd>
</kwd-group>
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