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Do patients with lymphoedema cholestasis syndrome 1/Aagenaes syndrome need dietary counselling outside cholestatic episodes?

Identifieur interne : 003924 ( Ncbi/Merge ); précédent : 003923; suivant : 003925

Do patients with lymphoedema cholestasis syndrome 1/Aagenaes syndrome need dietary counselling outside cholestatic episodes?

Auteurs : Monica Drivdal [Norvège] ; Elin Bj Rge L Ken ; Tor-Arne Hagve ; Ingunn Bergstad ; Ystein Aagenaes

Source :

RBID : pubmed:20170991

Descripteurs français

English descriptors

Abstract

Patients with lymphoedema cholestasis syndrome 1/Aagenaes Syndrome need a fat reduced diet when cholestatic. We wanted to assess the need for dietary counselling outside cholestatic episodes, and hypothetized that no counselling was needed.

DOI: 10.1016/j.clnu.2010.01.010
PubMed: 20170991

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pubmed:20170991

Le document en format XML

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<div type="abstract" xml:lang="en">Patients with lymphoedema cholestasis syndrome 1/Aagenaes Syndrome need a fat reduced diet when cholestatic. We wanted to assess the need for dietary counselling outside cholestatic episodes, and hypothetized that no counselling was needed.</div>
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<AbstractText Label="BACKGROUND & AIMS" NlmCategory="OBJECTIVE">Patients with lymphoedema cholestasis syndrome 1/Aagenaes Syndrome need a fat reduced diet when cholestatic. We wanted to assess the need for dietary counselling outside cholestatic episodes, and hypothetized that no counselling was needed.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Fifteen patients above 10 years of age without symptoms of cholestasis were compared with a sex and age matched control group. Diet from a four-day weighed record and blood samples were compared between the two groups and with general Norwegian recommendations.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The patients had a similar diet to the healthy controls, except for statistically significant lower intake of energy from total fat (p=0.04) and saturated fat (0.02), and fish (0.05). The patients met the dietary recommendations for macronutrients, except for saturated fat, monounsaturated fat, refined sugar and fibre. Supplements were needed to meet the micronutrient recommendations. Patients had a significantly lower serum level of alpha-tocopherol (0.01) compared with the control group, and the serum 25-OH D level was below reference ranges.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">The patients would benefit from counselling on fat quality, carbohydrates including fibre intake, and individual needs for vitamins D and E. To secure serum 25-OH D and alpha-tocopherol levels within reference ranges, regular examinations to determine the need for supplementary vitamins D and E are recommended.</AbstractText>
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