Case Report: Kaposiform Hemangioendothelioma in Multiple Spinal Levels Without Skin Changes
Identifieur interne : 003362 ( Ncbi/Merge ); précédent : 003361; suivant : 003363Case Report: Kaposiform Hemangioendothelioma in Multiple Spinal Levels Without Skin Changes
Auteurs : Jennifer W. Lisle [États-Unis] ; Heather A. Bradeen [États-Unis] ; Alexandra N. Kalof [États-Unis]Source :
- Clinical Orthopaedics and Related Research [ 0009-921X ] ; 2009.
Abstract
Kaposiform hemangioendothelioma is a rare vascular tumor of childhood that is locally aggressive but has little metastatic potential and by itself is not known to be lethal. It most commonly presents as a superficial or deep soft tissue mass with associated cutaneous lesions. Kasabach-Merritt phenomenon, a condition characterized by profound thrombocytopenia and life-threatening hemorrhage, often is associated with kaposiform hemangioendothelioma. Six cases of kaposiform hemangioendothelioma have been reported in bone, two of which were located in extracraniofacial bones. We report a diagnostically challenging case of a 6-year-old girl with kaposiform hemangioendothelioma of the thoracolumbar spine without Kasabach-Merritt phenomenon or cutaneous lesions.
Url:
DOI: 10.1007/s11999-009-0838-2
PubMed: 19381744
PubMed Central: 2866913
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PMC:2866913Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>Kaposiform hemangioendothelioma is a rare vascular tumor of childhood that is locally aggressive but has little metastatic potential and by itself is not known to be lethal. It most commonly presents as a superficial or deep soft tissue mass with associated cutaneous lesions. Kasabach-Merritt phenomenon, a condition characterized by profound thrombocytopenia and life-threatening hemorrhage, often is associated with kaposiform hemangioendothelioma. Six cases of kaposiform hemangioendothelioma have been reported in bone, two of which were located in extracraniofacial bones. We report a diagnostically challenging case of a 6-year-old girl with kaposiform hemangioendothelioma of the thoracolumbar spine without Kasabach-Merritt phenomenon or cutaneous lesions.</p>
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Department of Orthopedics and Rehabilitation, University of Vermont/Fletcher Allen Health Care, 426C Stafford Hall, 95 Carrigan Avenue, Burlington, VT 05405-0084 USA</aff>
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Department of Pediatrics, Hematology/Oncology, University of Vermont/Fletcher Allen Health Care, Burlington, VT USA</aff>
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Department of Pathology, University of Vermont/Fletcher Allen Health Care, Burlington, VT USA</aff>
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<permissions><copyright-statement>© The Association of Bone and Joint Surgeons 2009</copyright-statement>
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<abstract><p>Kaposiform hemangioendothelioma is a rare vascular tumor of childhood that is locally aggressive but has little metastatic potential and by itself is not known to be lethal. It most commonly presents as a superficial or deep soft tissue mass with associated cutaneous lesions. Kasabach-Merritt phenomenon, a condition characterized by profound thrombocytopenia and life-threatening hemorrhage, often is associated with kaposiform hemangioendothelioma. Six cases of kaposiform hemangioendothelioma have been reported in bone, two of which were located in extracraniofacial bones. We report a diagnostically challenging case of a 6-year-old girl with kaposiform hemangioendothelioma of the thoracolumbar spine without Kasabach-Merritt phenomenon or cutaneous lesions.</p>
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