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Case Report: Kaposiform Hemangioendothelioma in Multiple Spinal Levels Without Skin Changes

Identifieur interne : 000A10 ( Pmc/Curation ); précédent : 000A09; suivant : 000A11

Case Report: Kaposiform Hemangioendothelioma in Multiple Spinal Levels Without Skin Changes

Auteurs : Jennifer W. Lisle [États-Unis] ; Heather A. Bradeen [États-Unis] ; Alexandra N. Kalof [États-Unis]

Source :

RBID : PMC:2866913

Abstract

Kaposiform hemangioendothelioma is a rare vascular tumor of childhood that is locally aggressive but has little metastatic potential and by itself is not known to be lethal. It most commonly presents as a superficial or deep soft tissue mass with associated cutaneous lesions. Kasabach-Merritt phenomenon, a condition characterized by profound thrombocytopenia and life-threatening hemorrhage, often is associated with kaposiform hemangioendothelioma. Six cases of kaposiform hemangioendothelioma have been reported in bone, two of which were located in extracraniofacial bones. We report a diagnostically challenging case of a 6-year-old girl with kaposiform hemangioendothelioma of the thoracolumbar spine without Kasabach-Merritt phenomenon or cutaneous lesions.


Url:
DOI: 10.1007/s11999-009-0838-2
PubMed: 19381744
PubMed Central: 2866913

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PMC:2866913

Le document en format XML

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<p>Kaposiform hemangioendothelioma is a rare vascular tumor of childhood that is locally aggressive but has little metastatic potential and by itself is not known to be lethal. It most commonly presents as a superficial or deep soft tissue mass with associated cutaneous lesions. Kasabach-Merritt phenomenon, a condition characterized by profound thrombocytopenia and life-threatening hemorrhage, often is associated with kaposiform hemangioendothelioma. Six cases of kaposiform hemangioendothelioma have been reported in bone, two of which were located in extracraniofacial bones. We report a diagnostically challenging case of a 6-year-old girl with kaposiform hemangioendothelioma of the thoracolumbar spine without Kasabach-Merritt phenomenon or cutaneous lesions.</p>
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Department of Orthopedics and Rehabilitation, University of Vermont/Fletcher Allen Health Care, 426C Stafford Hall, 95 Carrigan Avenue, Burlington, VT 05405-0084 USA</aff>
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Department of Pediatrics, Hematology/Oncology, University of Vermont/Fletcher Allen Health Care, Burlington, VT USA</aff>
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<abstract>
<p>Kaposiform hemangioendothelioma is a rare vascular tumor of childhood that is locally aggressive but has little metastatic potential and by itself is not known to be lethal. It most commonly presents as a superficial or deep soft tissue mass with associated cutaneous lesions. Kasabach-Merritt phenomenon, a condition characterized by profound thrombocytopenia and life-threatening hemorrhage, often is associated with kaposiform hemangioendothelioma. Six cases of kaposiform hemangioendothelioma have been reported in bone, two of which were located in extracraniofacial bones. We report a diagnostically challenging case of a 6-year-old girl with kaposiform hemangioendothelioma of the thoracolumbar spine without Kasabach-Merritt phenomenon or cutaneous lesions.</p>
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